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Interactions between compounds and specific gene/protein targets.
| BIMP_ID | Target Name | Gene | Organism | Action | Source URL |
|---|---|---|---|---|---|
|
ABCC2
|
Homo sapiens (human)
|
ABCC2 protein affects the transport of etoposide
|
https://ctdbase.org/detail.go?type=gene&acc=1244
|
||
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ABCC2
|
Homo sapiens (human)
|
Probenecid promotes the reaction [ABCC2 protein affects the transport of etoposide]
|
https://ctdbase.org/detail.go?type=gene&acc=1244
|
||
|
ABCC2
|
Cyprinus carpio (common carp)
|
Ibuprofen results in increased expression of ABCC2 mRNA
|
https://ctdbase.org/detail.go?type=gene&acc=1244
|
||
|
ABCC2
|
Rattus norvegicus (Norway rat)
|
Indole-3-carbinol results in increased expression of ABCC2 mRNA
|
https://ctdbase.org/detail.go?type=gene&acc=1244
|
||
|
ABCC2
|
Mus musculus (house mouse)
|
Glyburide results in increased expression of ABCC2 mRNA
|
https://ctdbase.org/detail.go?type=gene&acc=1244
|
||
|
ABCC2
|
Rattus norvegicus (Norway rat)
|
Glyburide results in increased expression of ABCC2 mRNA
|
https://ctdbase.org/detail.go?type=gene&acc=1244
|
||
|
ABCC2
|
Rattus norvegicus (Norway rat)
|
[diethylnitrosamine co-treated with kojic acid co-treated with diethylnitrosamine] results in increased expression of ABCC2 mrna|[diethylnitrosamine co-treated with kojic acid] results in decreased expression of ABCC2 mRNA
|
https://ctdbase.org/detail.go?type=gene&acc=1244
|
||
|
ABCC2
|
Homo sapiens (human)
|
2-(4-morpholinyl)-8-phenyl-4H-1-benzopyran-4-one inhibits the reaction [erucin results in increased expression of ABCC2 mrna]
|
https://ctdbase.org/detail.go?type=gene&acc=1244
|
||
|
ABCC2
|
Homo sapiens (human)
|
Loratadine inhibits the reaction [ABCC2 protein results in increased export of fosinopril]
|
https://ctdbase.org/detail.go?type=gene&acc=1244
|
||
|
ABCC2
|
Homo sapiens (human)
|
Indomethacin inhibits the reaction [methoxsalen results in decreased activity of ABCC2 protein]|[methoxsalen results in decreased activity of ABCC2 protein] which results in decreased export of and results in increased abundance of daunorubicin|methoxsalen results in decreased activity of ABCC2 protein|indomethacin inhibits the reaction [[methoxsalen results in decreased activity of ABCC2 protein] which results in decreased export of and results in increased abundance of daunorubicin]|methoxsalen results in decreased expression of ABCC2 mRNA
|
https://ctdbase.org/detail.go?type=gene&acc=1244
|
||
|
ABCC2
|
Homo sapiens (human)
|
|
https://www.dgidb.org/genes/hgnc:53
|
||
|
ABCC2
|
Homo sapiens (human)
|
3',4',7-trihydroxyisoflavone inhibits the reaction [epirubicin results in increased expression of ABCC2 mrna]
|
https://ctdbase.org/detail.go?type=gene&acc=1244
|
||
|
ABCC2
|
Homo sapiens (human)
|
Epirubicin analog results in increased expression of ABCC2 mRNA
|
https://ctdbase.org/detail.go?type=gene&acc=1244
|
||
|
ABCC2
|
Homo sapiens (human)
|
Epirubicin results in increased expression of ABCC2 mRNA
|
https://ctdbase.org/detail.go?type=gene&acc=1244
|
||
|
ABCC2
|
Homo sapiens (human)
|
Formononetin inhibits the reaction [epirubicin results in increased expression of ABCC2 mrna]
|
https://ctdbase.org/detail.go?type=gene&acc=1244
|
||
|
ABCC2
|
Homo sapiens (human)
|
Mitotane results in increased expression of ABCC2 mRNA
|
https://ctdbase.org/detail.go?type=gene&acc=1244
|
||
|
ABCC2
|
Sus scrofa (pig)
|
Deoxynivalenol results in increased expression of ABCC2 mRNA
|
https://ctdbase.org/detail.go?type=gene&acc=1244
|
||
|
ABCC2
|
Homo sapiens (human)
|
ABCC2 protein results in increased transport of notoginsenoside R1
|
https://ctdbase.org/detail.go?type=gene&acc=1244
|
||
|
ABCC2
|
Homo sapiens (human)
|
Polyphenols inhibits the reaction [ABCC2 protein affects the export of ochratoxin a]|biochanin A inhibits the reaction [ABCC2 protein affects the export of ochratoxin a]|resveratrol inhibits the reaction [ABCC2 protein affects the export of ochratoxin a]|chrysin inhibits the reaction [ABCC2 protein affects the export of ochratoxin a]|quercetin inhibits the reaction [ABCC2 protein affects the export of ochratoxin a]|genistein inhibits the reaction [ABCC2 protein affects the export of ochratoxin a]|polyphenols metabolite inhibits the reaction [ABCC2 protein affects the export of ochratoxin A]|ABCC2 protein affects the export of ochratoxin A
|
https://ctdbase.org/detail.go?type=gene&acc=1244
|
||
|
ABCC2
|
Homo sapiens (human)
|
ABCC2 protein affects the transport of ochratoxin A
|
https://ctdbase.org/detail.go?type=gene&acc=1244
|
||
|
ABCC2
|
Homo sapiens (human)
|
Ochratoxin A results in decreased expression of ABCC2 mRNA
|
https://ctdbase.org/detail.go?type=gene&acc=1244
|
||
|
ABCC2
|
Mus musculus (house mouse)
|
ABCC2 protein affects the transport of ochratoxin A
|
https://ctdbase.org/detail.go?type=gene&acc=1244
|
||
|
ABCC2
|
Rattus norvegicus (Norway rat)
|
Ochratoxin A results in decreased expression of ABCC2 mRNA
|
https://ctdbase.org/detail.go?type=gene&acc=1244
|
||
|
ABCC2
|
Rattus norvegicus (Norway rat)
|
Ochratoxin A results in increased expression of ABCC2 mRNA
|
https://ctdbase.org/detail.go?type=gene&acc=1244
|
||
|
ABCC2
|
Homo sapiens (human)
|
[verlukast results in decreased activity of ABCC2 protein] which results in decreased transport of hypaconitine
|
https://ctdbase.org/detail.go?type=gene&acc=1244
|
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