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Interactions between compounds and specific gene/protein targets.
| BIMP_ID | Target Name | Gene | Organism | Action | Source URL |
|---|---|---|---|---|---|
|
ABCC2
|
Fundulus lima (killifish)
|
Nifedipine inhibits the reaction [cadmium chloride results in decreased activity of ABCC2 protein]|nifedipine inhibits the reaction [mercuric chloride results in decreased activity of ABCC2 protein]
|
https://ctdbase.org/detail.go?type=gene&acc=1244
|
||
|
ABCC2
|
Rattus norvegicus (Norway rat)
|
Nifedipine results in increased expression of ABCC2 mRNA
|
https://ctdbase.org/detail.go?type=gene&acc=1244
|
||
|
ABCC2
|
Homo sapiens (human)
|
ABCC2 protein affects the export of resveratrol
|
https://ctdbase.org/detail.go?type=gene&acc=1244
|
||
|
ABCC2
|
Homo sapiens (human)
|
Resveratrol inhibits the reaction [ABCC2 protein affects the export of ochratoxin A]
|
https://ctdbase.org/detail.go?type=gene&acc=1244
|
||
|
ABCC2
|
Homo sapiens (human)
|
Resveratrol inhibits the reaction [genistein promotes the reaction [RXRA protein binds to ABCC2 promoter]]
|
https://ctdbase.org/detail.go?type=gene&acc=1244
|
||
|
ABCC2
|
Homo sapiens (human)
|
Resveratrol inhibits the reaction [genistein results in increased expression of ABCC2 mrna]|resveratrol inhibits the reaction [genistein results in increased expression of ABCC2 protein]
|
https://ctdbase.org/detail.go?type=gene&acc=1244
|
||
|
ABCC2
|
Homo sapiens (human)
|
Resveratrol results in decreased expression of ABCC2 mrna|resveratrol results in decreased expression of ABCC2 protein
|
https://ctdbase.org/detail.go?type=gene&acc=1244
|
||
|
ABCC2
|
Rattus norvegicus (Norway rat)
|
[probenecid results in decreased activity of ABCC2 protein] which results in decreased secretion of resveratrol metabolite|[verlukast results in decreased activity of ABCC2 protein] which results in decreased secretion of resveratrol metabolite
|
https://ctdbase.org/detail.go?type=gene&acc=1244
|
||
|
ABCC2
|
Rattus norvegicus (Norway rat)
|
Resveratrol inhibits the reaction [1-naphthylisothiocyanate results in decreased expression of ABCC2 protein]|resveratrol inhibits the reaction [1-naphthylisothiocyanate results in decreased expression of ABCC2 mrna]
|
https://ctdbase.org/detail.go?type=gene&acc=1244
|
||
|
ABCC2
|
Homo sapiens (human)
|
Resveratrol inhibits the reaction [ABCC2 protein results in increased transport of methotrexate]
|
https://ctdbase.org/detail.go?type=gene&acc=1244
|
||
|
ABCC2
|
Homo sapiens (human)
|
[[chlorpyrifos co-treated with decamethrin co-treated with polymarcine co-treated with glyphosate] results in decreased susceptibility to temozolomide] which results in increased expression of ABCC2 mrna|[[chlorpyrifos co-treated with decamethrin co-treated with polymarcine co-treated with glyphosate] results in decreased susceptibility to cisplatin] which results in increased expression of ABCC2 mrna|[[chlorpyrifos co-treated with decamethrin co-treated with polymarcine co-treated with glyphosate] results in decreased susceptibility to fluorouracil] which results in increased expression of ABCC2 mRNA
|
https://ctdbase.org/detail.go?type=gene&acc=1244
|
||
|
ABCC2
|
Homo sapiens (human)
|
ABCC2 protein affects the susceptibility to fluorouracil
|
https://ctdbase.org/detail.go?type=gene&acc=1244
|
||
|
ABCC2
|
Homo sapiens (human)
|
[[chlorpyrifos co-treated with decamethrin co-treated with polymarcine co-treated with glyphosate] results in decreased susceptibility to fluorouracil] which results in increased expression of ABCC2 mRNA
|
https://ctdbase.org/detail.go?type=gene&acc=1244
|
||
|
ABCC2
|
Homo sapiens (human)
|
|
https://www.dgidb.org/genes/hgnc:53
|
||
|
ABCC2
|
Homo sapiens (human)
|
ABCC2 protein results in increased transport of ethacrynic acid
|
https://ctdbase.org/detail.go?type=gene&acc=1244
|
||
|
ABCC2
|
Homo sapiens (human)
|
Indomethacin inhibits the reaction [[5-methoxypsoralen results in decreased activity of ABCC2 protein] which results in decreased export of and results in increased abundance of daunorubicin]|indomethacin inhibits the reaction [methoxsalen results in decreased activity of ABCC2 protein]|indomethacin inhibits the reaction [[methoxsalen results in decreased activity of ABCC2 protein] which results in decreased export of and results in increased abundance of daunorubicin]|indomethacin inhibits the reaction [5-methoxypsoralen results in decreased activity of ABCC2 protein]
|
https://ctdbase.org/detail.go?type=gene&acc=1244
|
||
|
ABCC2
|
Homo sapiens (human)
|
Indomethacin inhibits the reaction [ABCC2 protein affects the export of 5-carboxyfluorescein diacetate]
|
https://ctdbase.org/detail.go?type=gene&acc=1244
|
||
|
ABCC2
|
Homo sapiens (human)
|
Indomethacin promotes the reaction [ABCC2 protein affects the transport of estradiol-17 beta-glucuronide]
|
https://ctdbase.org/detail.go?type=gene&acc=1244
|
||
|
ABCC2
|
Homo sapiens (human)
|
Indomethacin results in decreased activity of ABCC2 protein
|
https://ctdbase.org/detail.go?type=gene&acc=1244
|
||
|
ABCC2
|
Rattus norvegicus (Norway rat)
|
Indomethacin results in decreased activity of ABCC2 protein
|
https://ctdbase.org/detail.go?type=gene&acc=1244
|
||
|
ABCC2
|
Rattus norvegicus (Norway rat)
|
Indomethacin results in decreased expression of ABCC2 protein|indomethacin results in decreased expression of ABCC2 mRNA
|
https://ctdbase.org/detail.go?type=gene&acc=1244
|
||
|
ABCC2
|
Rattus norvegicus (Norway rat)
|
Gentamicins results in increased expression of ABCC2 mRNA
|
https://ctdbase.org/detail.go?type=gene&acc=1244
|
||
|
ABCC2
|
Rattus norvegicus (Norway rat)
|
Gentamicins results in increased expression of ABCC2 protein
|
https://ctdbase.org/detail.go?type=gene&acc=1244
|
||
|
ABCC2
|
Homo sapiens (human)
|
Fluoxetine results in increased expression of ABCC2 mRNA
|
https://ctdbase.org/detail.go?type=gene&acc=1244
|
||
|
ABCC2
|
Homo sapiens (human)
|
Sodium dodecyl sulfate results in increased expression of ABCC2 mRNA
|
https://ctdbase.org/detail.go?type=gene&acc=1244
|
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