Molecular Targets : Dataset Browser

BIMP_ID	Target Name	Gene	Organism	Action	Source URL
BIMP068606	ABCC2	ABCC2	Homo sapiens (human)	5-methoxypsoralen results in decreased expression of ABCC2 mrna\|indomethacin inhibits the reaction [[5-methoxypsoralen results in decreased activity of ABCC2 protein] which results in decreased export of and results in increased abundance of daunorubicin]\|5-methoxypsoralen results in decreased activity of ABCC2 protein\|[5-methoxypsoralen results in decreased activity of ABCC2 protein] which results in decreased export of and results in increased abundance of daunorubicin\|indomethacin inhibits the reaction [5-methoxypsoralen results in decreased activity of ABCC2 protein]	https://ctdbase.org/detail.go?type=gene&acc=1244
BIMP070301	ABCC2	ABCC2	Homo sapiens (human)	Verapamil inhibits the reaction [ABCC2 protein affects the export of 5-carboxyfluorescein diacetate]	https://ctdbase.org/detail.go?type=gene&acc=1244
BIMP070301	ABCC2	ABCC2	Rattus	Verapamil results in decreased activity of ABCC2 protein	https://ctdbase.org/detail.go?type=gene&acc=1244
BIMP070955	ABCC2	ABCC2	Homo sapiens (human)	Butyraldehyde results in decreased expression of ABCC2 mRNA	https://ctdbase.org/detail.go?type=gene&acc=1244
BIMP071142	ABCC2	ABCC2	Homo sapiens (human)	Chloroquine results in decreased expression of ABCC2 protein\|chloroquine results in decreased expression of ABCC2 mRNA	https://ctdbase.org/detail.go?type=gene&acc=1244
BIMP069573	ABCC2	ABCC2	Homo sapiens (human)	[verlukast results in decreased activity of ABCC2 protein] which results in decreased transport of benzoylmesaconine	https://ctdbase.org/detail.go?type=gene&acc=1244
BIMP070286	ABCC2	ABCC2	Homo sapiens (human)	Caffeine results in increased phosphorylation of ABCC2 protein	https://ctdbase.org/detail.go?type=gene&acc=1244
BIMP070286	ABCC2	ABCC2	Mus musculus (house mouse)	[caffeine co-treated with coclaurine co-treated with aegeline co-treated with higenamine co-treated with yohimbine co-treated with hydrolyzable tannins] results in increased expression of ABCC2 mRNA	https://ctdbase.org/detail.go?type=gene&acc=1244
BIMP072381	ABCC2	ABCC2	Homo sapiens (human)	Coumarin results in decreased phosphorylation of ABCC2 protein	https://ctdbase.org/detail.go?type=gene&acc=1244
BIMP072264	ABCC2	ABCC2	Homo sapiens (human)	Ursodeoxycholic acid results in increased expression of ABCC2	https://ctdbase.org/detail.go?type=gene&acc=1244
BIMP072264	ABCC2	ABCC2	Homo sapiens (human)	Ursodeoxycholic acid results in increased expression of ABCC2 protein	https://ctdbase.org/detail.go?type=gene&acc=1244
BIMP072264	ABCC2	ABCC2	Mus musculus (house mouse)	NFE2L2 affects the reaction [ursodeoxycholic acid results in increased expression of ABCC2 protein]\|nfe2l2 affects the reaction [ursodeoxycholic acid results in increased expression of ABCC2 mrna]	https://ctdbase.org/detail.go?type=gene&acc=1244
BIMP072264	ABCC2	ABCC2	Mus musculus (house mouse)	Ursodeoxycholic acid results in increased expression of ABCC2 mRNA	https://ctdbase.org/detail.go?type=gene&acc=1244
BIMP072264	ABCC2	ABCC2	Mus musculus (house mouse)	Ursodeoxycholic acid results in increased expression of ABCC2 protein	https://ctdbase.org/detail.go?type=gene&acc=1244
BIMP072264	ABCC2	ABCC2	Rattus norvegicus (Norway rat)	ABCC2 affects the reaction [ursodeoxycholic acid results in increased secretion of nitric oxide]	https://ctdbase.org/detail.go?type=gene&acc=1244
BIMP072264	ABCC2	ABCC2	Rattus norvegicus (Norway rat)	Ursodeoxycholic acid inhibits the reaction [ethinyl estradiol results in decreased expression of ABCC2 mrna]\|n-(2-(4-bromocinnamylamino)ethyl)-5-isoquinolinesulfonamide inhibits the reaction [ursodeoxycholic acid inhibits the reaction [ethinyl estradiol results in decreased expression of ABCC2 mrna]]	https://ctdbase.org/detail.go?type=gene&acc=1244
BIMP072264	ABCC2	ABCC2	Rattus norvegicus (Norway rat)	Ursodeoxycholic acid affects the expression of ABCC2 mrna\|ursodeoxycholic acid affects the expression of ABCC2 protein	https://ctdbase.org/detail.go?type=gene&acc=1244
BIMP072264	ABCC2	ABCC2	Rattus norvegicus (Norway rat)	Ursodeoxycholic acid inhibits the reaction [1-naphthylisothiocyanate results in decreased expression of ABCC2 mrna]	https://ctdbase.org/detail.go?type=gene&acc=1244
BIMP072264	ABCC2	ABCC2	Rattus norvegicus (Norway rat)	Ursodeoxycholic acid inhibits the reaction [1-naphthylisothiocyanate results in decreased expression of ABCC2 protein]	https://ctdbase.org/detail.go?type=gene&acc=1244
BIMP072264	ABCC2	ABCC2	Rattus norvegicus (Norway rat)	Ursodeoxycholic acid results in increased activity of ABCC2 protein\|ursodeoxycholic acid inhibits the reaction [ethinyl estradiol results in decreased activity of ABCC2 protein]	https://ctdbase.org/detail.go?type=gene&acc=1244
BIMP072264	ABCC2	ABCC2	Rattus norvegicus (Norway rat)	Ursodeoxycholic acid promotes the reaction [ABCC2 protein results in increased export of S-(2,4-dinitrophenyl)glutathione]\|ursodeoxycholic acid results in increased expression of ABCC2 mrna\|ursodeoxycholic acid results in increased expression of ABCC2 protein	https://ctdbase.org/detail.go?type=gene&acc=1244
BIMP072286	ABCC2	ABCC2	Homo sapiens (human)	Benzonidazole results in increased expression of ABCC2 protein\|nfe2l2 protein affects the reaction [benzonidazole results in increased expression of ABCC2 mrna]\|benzonidazole results in increased expression of ABCC2 mrna\|nfe2l2 protein affects the reaction [benzonidazole results in increased expression of ABCC2 protein]	https://ctdbase.org/detail.go?type=gene&acc=1244
BIMP072300	ABCC2	ABCC2	Mus musculus (house mouse)	ABCC2 protein affects the transport of doxorubicin	https://ctdbase.org/detail.go?type=gene&acc=1244
BIMP072300	ABCC2	ABCC2	Rattus norvegicus (Norway rat)	ABCC2 protein results in decreased susceptibility to doxorubicin	https://ctdbase.org/detail.go?type=gene&acc=1244
BIMP078516	ABCC2	ABCC2	Homo sapiens (human)		https://www.dgidb.org/genes/hgnc:53

BIMP068606

ABCC2

Homo sapiens (human)

5-methoxypsoralen results in decreased expression of ABCC2 mrna|indomethacin inhibits the reaction [[5-methoxypsoralen results in decreased activity of ABCC2 protein] which results in decreased export of and results in increased abundance of daunorubicin]|5-methoxypsoralen results in decreased activity of ABCC2 protein|[5-methoxypsoralen results in decreased activity of ABCC2 protein] which results in decreased export of and results in increased abundance of daunorubicin|indomethacin inhibits the reaction [5-methoxypsoralen results in decreased activity of ABCC2 protein]