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Interactions between compounds and specific gene/protein targets.
| BIMP_ID | Target Name | Gene | Organism | Action | Source URL |
|---|---|---|---|---|---|
|
ABCC2
|
Rattus norvegicus (Norway rat)
|
Bilirubin results in decreased activity of ABCC2 protein
|
https://ctdbase.org/detail.go?type=gene&acc=1244
|
||
|
ABCC2
|
Homo sapiens (human)
|
ABCC2 protein affects the transport of bilirubin
|
https://ctdbase.org/detail.go?type=gene&acc=1244
|
||
|
ABCC2
|
Mus musculus (house mouse)
|
[luteolin co-treated with cisplatin] results in increased expression of ABCC2 protein|luteolin inhibits the reaction [cisplatin results in increased expression of ABCC2 protein]
|
https://ctdbase.org/detail.go?type=gene&acc=1244
|
||
|
ABCC2
|
Homo sapiens (human)
|
Calcitriol results in increased expression of ABCC2 mRNA
|
https://ctdbase.org/detail.go?type=gene&acc=1244
|
||
|
ABCC2
|
Rattus norvegicus (Norway rat)
|
Calcitriol results in increased activity of ABCC2 protein|calcitriol results in increased expression of ABCC2 protein
|
https://ctdbase.org/detail.go?type=gene&acc=1244
|
||
|
ABCC2
|
Mus musculus (house mouse)
|
Piperonyl butoxide results in increased expression of ABCC2 mRNA
|
https://ctdbase.org/detail.go?type=gene&acc=1244
|
||
|
ABCC2
|
Rattus norvegicus (Norway rat)
|
[ethinyl estradiol co-treated with spironolactone] results in increased expression of ABCC2 protein
|
https://ctdbase.org/detail.go?type=gene&acc=1244
|
||
|
ABCC2
|
Rattus norvegicus (Norway rat)
|
Ketoconazole inhibits the reaction [spironolactone results in increased expression of ABCC2 mrna]|[spironolactone results in increased expression of ABCC2 protein] which results in increased transport of S-(2,4-dinitrophenyl)glutathione
|
https://ctdbase.org/detail.go?type=gene&acc=1244
|
||
|
ABCC2
|
Rattus norvegicus (Norway rat)
|
Spironolactone results in increased expression of ABCC2 mRNA
|
https://ctdbase.org/detail.go?type=gene&acc=1244
|
||
|
ABCC2
|
Rattus norvegicus (Norway rat)
|
Spironolactone results in increased expression of ABCC2 protein
|
https://ctdbase.org/detail.go?type=gene&acc=1244
|
||
|
ABCC2
|
Homo sapiens (human)
|
ABCC2 protein affects the metabolism of adenosine triphosphate
|
https://ctdbase.org/detail.go?type=gene&acc=1244
|
||
|
ABCC2
|
Homo sapiens (human)
|
Adenosine triphosphate affects the activity of ABCC2 protein|[adenosine triphosphate affects the activity of ABCC2 protein] which results in increased transport of acetaminophen metabolite
|
https://ctdbase.org/detail.go?type=gene&acc=1244
|
||
|
ABCC2
|
Homo sapiens (human)
|
Adenosine triphosphate affects the reaction [ABCC2 protein results in increased transport of mercury]
|
https://ctdbase.org/detail.go?type=gene&acc=1244
|
||
|
ABCC2
|
Homo sapiens (human)
|
[adenosine triphosphate co-treated with ABCC2 protein] results in increased uptake of estradiol-17 beta-glucuronide|verlukast inhibits the reaction [[adenosine triphosphate co-treated with ABCC2 protein] results in increased uptake of estradiol-17 beta-glucuronide]
|
https://ctdbase.org/detail.go?type=gene&acc=1244
|
||
|
ABCC2
|
Mus musculus (house mouse)
|
Adenosine triphosphate promotes the reaction [ABCC2 protein results in increased transport of S-1,2-dichlorovinyl-N-acetylcysteine]
|
https://ctdbase.org/detail.go?type=gene&acc=1244
|
||
|
ABCC2
|
Rattus norvegicus (Norway rat)
|
Adenosine triphosphate promotes the reaction [ABCC2 protein results in increased secretion of fluo-3]
|
https://ctdbase.org/detail.go?type=gene&acc=1244
|
||
|
ABCC2
|
Rattus norvegicus (Norway rat)
|
Adenosine triphosphate promotes the reaction [ABCC2 protein results in increased transport of temocaprilat]
|
https://ctdbase.org/detail.go?type=gene&acc=1244
|
||
|
ABCC2
|
Homo sapiens (human)
|
Penicillin G promotes the reaction [ABCC2 protein affects the transport of estradiol-17 beta-glucuronide]
|
https://ctdbase.org/detail.go?type=gene&acc=1244
|
||
|
ABCC2
|
Rattus norvegicus (Norway rat)
|
Penicillin G results in increased activity of ABCC2 protein
|
https://ctdbase.org/detail.go?type=gene&acc=1244
|
||
|
ABCC2
|
Homo sapiens (human)
|
Benzo(a)pyrene results in decreased expression of ABCC2 mRNA
|
https://ctdbase.org/detail.go?type=gene&acc=1244
|
||
|
ABCC2
|
Homo sapiens (human)
|
Benzo(a)pyrene results in increased expression of ABCC2 mRNA
|
https://ctdbase.org/detail.go?type=gene&acc=1244
|
||
|
ABCC2
|
Homo sapiens (human)
|
Benzo(a)pyrene results in increased methylation of ABCC2 intron|benzo(a)pyrene results in increased methylation of ABCC2 exon|benzo(a)pyrene results in increased methylation of ABCC2 promoter
|
https://ctdbase.org/detail.go?type=gene&acc=1244
|
||
|
ABCC2
|
Mus musculus (house mouse)
|
ABCC2 protein results in increased transport of benzo(a)pyrene|abcc2 protein results in increased transport of benzo(a)pyrene metabolite
|
https://ctdbase.org/detail.go?type=gene&acc=1244
|
||
|
ABCC2
|
Mus musculus (house mouse)
|
Benzo(a)pyrene results in increased expression of ABCC2 mRNA
|
https://ctdbase.org/detail.go?type=gene&acc=1244
|
||
|
ABCC2
|
Oreochromis niloticus (Nile tilapia)
|
Benzo(a)pyrene results in increased expression of ABCC2 mRNA
|
https://ctdbase.org/detail.go?type=gene&acc=1244
|
No matching records found on this page.