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Interactions between compounds and specific gene/protein targets.
| BIMP_ID | Target Name | Gene | Organism | Action | Source URL |
|---|---|---|---|---|---|
|
ABCC2
|
Homo sapiens (human)
|
Probenecid inhibits the reaction [ABCC2 protein affects the export of 6-carboxyfluorescein]
|
https://ctdbase.org/detail.go?type=gene&acc=1244
|
||
|
ABCC2
|
Homo sapiens (human)
|
Probenecid inhibits the reaction [ABCC2 protein results in increased export of 5(6)-carboxy-2',7'-dichlorofluorescein analog]
|
https://ctdbase.org/detail.go?type=gene&acc=1244
|
||
|
ABCC2
|
Homo sapiens (human)
|
Probenecid promotes the reaction [ABCC2 protein affects the transport of etoposide]|probenecid promotes the reaction [ABCC2 protein affects the transport of docetaxel]|probenecid promotes the reaction [ABCC2 protein affects the transport of paclitaxel]|probenecid promotes the reaction [ABCC2 protein affects the transport of vinblastine]|probenecid promotes the reaction [ABCC2 protein results in decreased susceptibility to paclitaxel]
|
https://ctdbase.org/detail.go?type=gene&acc=1244
|
||
|
ABCC2
|
Rattus norvegicus (Norway rat)
|
ABCC2 protein results in increased export of probenecid
|
https://ctdbase.org/detail.go?type=gene&acc=1244
|
||
|
ABCC2
|
Rattus norvegicus (Norway rat)
|
Probenecid results in decreased activity of ABCC2 protein|[probenecid results in decreased activity of ABCC2 protein] which results in decreased secretion of resveratrol metabolite
|
https://ctdbase.org/detail.go?type=gene&acc=1244
|
||
|
ABCC2
|
Rattus norvegicus (Norway rat)
|
[probenecid results in decreased activity of ABCC2 protein] which results in decreased secretion of rosuvastatin calcium
|
https://ctdbase.org/detail.go?type=gene&acc=1244
|
||
|
ABCC2
|
Rattus norvegicus (Norway rat)
|
Probenecid results in increased activity of ABCC2 protein
|
https://ctdbase.org/detail.go?type=gene&acc=1244
|
||
|
ABCC2
|
Mus musculus (house mouse)
|
[liquiritin co-treated with 1-naphthylisothiocyanate] results in decreased expression of ABCC2 mRNA
|
https://ctdbase.org/detail.go?type=gene&acc=1244
|
||
|
ABCC2
|
Homo sapiens (human)
|
Probenecid promotes the reaction [ABCC2 protein affects the transport of estradiol-17 beta-glucuronide]
|
https://ctdbase.org/detail.go?type=gene&acc=1244
|
||
|
ABCC2
|
Homo sapiens (human)
|
Probenecid results in increased activity of ABCC2 protein
|
https://ctdbase.org/detail.go?type=gene&acc=1244
|
||
|
ABCC2
|
Cyprinus carpio (common carp)
|
Propranolol results in increased expression of ABCC2 mRNA
|
https://ctdbase.org/detail.go?type=gene&acc=1244
|
||
|
ABCC2
|
Canis lupus familiaris (dog)
|
ABCC2 protein affects the transport of leukotriene C4
|
https://ctdbase.org/detail.go?type=gene&acc=1244
|
||
|
ABCC2
|
Homo sapiens (human)
|
ABCC2 protein affects the transport of leukotriene C4
|
https://ctdbase.org/detail.go?type=gene&acc=1244
|
||
|
ABCC2
|
Homo sapiens (human)
|
Verlukast inhibits the reaction [ABCC2 protein results in increased transport of leukotriene C4]
|
https://ctdbase.org/detail.go?type=gene&acc=1244
|
||
|
ABCC2
|
Oryctolagus cuniculus (rabbit)
|
ABCC2 protein affects the transport of leukotriene c4|leukotriene C4 inhibits the reaction [ABCC2 protein affects the transport of estradiol-17 beta-glucuronide]
|
https://ctdbase.org/detail.go?type=gene&acc=1244
|
||
|
ABCC2
|
Rattus norvegicus (Norway rat)
|
ABCC2 protein affects the transport of leukotriene C4
|
https://ctdbase.org/detail.go?type=gene&acc=1244
|
||
|
ABCC2
|
Rattus norvegicus (Norway rat)
|
ABCC2 protein modified form results in increased transport of leukotriene C4
|
https://ctdbase.org/detail.go?type=gene&acc=1244
|
||
|
ABCC2
|
Homo sapiens (human)
|
Coniferaldehyde results in increased expression of ABCC2 mRNA
|
https://ctdbase.org/detail.go?type=gene&acc=1244
|
||
|
ABCC2
|
Homo sapiens (human)
|
Quercetin inhibits the reaction [ABCC2 protein affects the export of ochratoxin A]
|
https://ctdbase.org/detail.go?type=gene&acc=1244
|
||
|
ABCC2
|
Rattus norvegicus (Norway rat)
|
Quercetin inhibits the reaction [sodium arsenite results in increased expression of ABCC2 mrna]
|
https://ctdbase.org/detail.go?type=gene&acc=1244
|
||
|
ABCC2
|
Homo sapiens (human)
|
Biochanin A inhibits the reaction [ABCC2 protein affects the export of ochratoxin A]
|
https://ctdbase.org/detail.go?type=gene&acc=1244
|
||
|
ABCC2
|
Homo sapiens (human)
|
Formononetin inhibits the reaction [epirubicin results in increased expression of ABCC2 mrna]|formononetin results in decreased expression of ABCC2 mrna|acetylcysteine inhibits the reaction [formononetin results in decreased expression of ABCC2 mrna]
|
https://ctdbase.org/detail.go?type=gene&acc=1244
|
||
|
ABCC2
|
Rattus norvegicus (Norway rat)
|
Formononetin promotes the reaction [cisplatin results in increased expression of ABCC2 mrna]
|
https://ctdbase.org/detail.go?type=gene&acc=1244
|
||
|
ABCC2
|
Rattus norvegicus (Norway rat)
|
ABCC2 protein affects the transport of bilirubin
|
https://ctdbase.org/detail.go?type=gene&acc=1244
|
||
|
ABCC2
|
Rattus norvegicus (Norway rat)
|
Bilirubin analog inhibits the reaction [tert-butylhydroperoxide affects the localization of and results in decreased activity of ABCC2 protein]
|
https://ctdbase.org/detail.go?type=gene&acc=1244
|
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