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Interactions between compounds and specific gene/protein targets.
| BIMP_ID | Target Name | Gene | Organism | Action | Source URL |
|---|---|---|---|---|---|
|
ABCC2
|
Homo sapiens (human)
|
Triclosan results in increased expression of ABCC2 mRNA
|
https://ctdbase.org/detail.go?type=gene&acc=1244
|
||
|
ABCC2
|
Homo sapiens (human)
|
Demethoxycurcumin results in decreased activity of ABCC2 protein
|
https://ctdbase.org/detail.go?type=gene&acc=1244
|
||
|
ABCC2
|
Homo sapiens (human)
|
Baohuoside I results in decreased expression of ABCC2 mrna|baohuoside I results in decreased expression of ABCC2 protein
|
https://ctdbase.org/detail.go?type=gene&acc=1244
|
||
|
ABCC2
|
Mus musculus (house mouse)
|
Mifepristone results in increased expression of ABCC2 mRNA
|
https://ctdbase.org/detail.go?type=gene&acc=1244
|
||
|
ABCC2
|
Danio rerio (zebrafish)
|
Tetracycline affects the expression of ABCC2 mRNA
|
https://ctdbase.org/detail.go?type=gene&acc=1244
|
||
|
ABCC2
|
Rattus norvegicus (Norway rat)
|
Tetracycline results in decreased expression of ABCC2 mRNA
|
https://ctdbase.org/detail.go?type=gene&acc=1244
|
||
|
ABCC2
|
Homo sapiens (human)
|
Ascorbic acid inhibits the reaction [3',4',7-trihydroxyisoflavone results in decreased expression of ABCC2 mrna]
|
https://ctdbase.org/detail.go?type=gene&acc=1244
|
||
|
ABCC2
|
Homo sapiens (human)
|
Ascorbic acid inhibits the reaction [4-hydroxy-2-nonenal inhibits the reaction [ABCC2 protein results in increased transport of 5(6)-carboxy-2',7'-dichlorofluorescein]]|ascorbic acid promotes the reaction [ABCC2 protein results in increased transport of 5(6)-carboxy-2',7'-dichlorofluorescein]
|
https://ctdbase.org/detail.go?type=gene&acc=1244
|
||
|
ABCC2
|
Rattus norvegicus (Norway rat)
|
Ascorbic acid inhibits the reaction [fructose results in decreased expression of ABCC2 protein]|ascorbic acid inhibits the reaction [fructose results in decreased expression of ABCC2 mrna]
|
https://ctdbase.org/detail.go?type=gene&acc=1244
|
||
|
ABCC2
|
Homo sapiens (human)
|
[pirinixic acid binds to and results in increased activity of PPARA protein] which results in increased expression of ABCC2 mRNA
|
https://ctdbase.org/detail.go?type=gene&acc=1244
|
||
|
ABCC2
|
Rattus norvegicus (Norway rat)
|
Pirinixic acid results in decreased expression of ABCC2 mRNA
|
https://ctdbase.org/detail.go?type=gene&acc=1244
|
||
|
ABCC2
|
Canis lupus familiaris (dog)
|
ABCC2 protein affects the transport of estradiol
|
https://ctdbase.org/detail.go?type=gene&acc=1244
|
||
|
ABCC2
|
Homo sapiens (human)
|
Estradiol results in increased expression of ABCC2 mrna|estradiol results in increased expression of ABCC2 protein
|
https://ctdbase.org/detail.go?type=gene&acc=1244
|
||
|
ABCC2
|
Mus musculus (house mouse)
|
Estradiol results in decreased expression of ABCC2 mrna|estradiol results in decreased expression of ABCC2 protein
|
https://ctdbase.org/detail.go?type=gene&acc=1244
|
||
|
ABCC2
|
Rattus norvegicus (Norway rat)
|
Estradiol affects the localization of and affects the activity of ABCC2 protein
|
https://ctdbase.org/detail.go?type=gene&acc=1244
|
||
|
ABCC2
|
Rattus norvegicus (Norway rat)
|
Estradiol results in decreased expression of ABCC2 mRNA
|
https://ctdbase.org/detail.go?type=gene&acc=1244
|
||
|
ABCC2
|
Homo sapiens (human)
|
ABCC2 protein results in increased uptake of estradiol|raloxifene-4'-beta-glucuronide inhibits the reaction [ABCC2 protein results in increased uptake of estradiol]
|
https://ctdbase.org/detail.go?type=gene&acc=1244
|
||
|
ABCC2
|
Homo sapiens (human)
|
Dexamethasone results in increased expression of ABCC2 mRNA
|
https://ctdbase.org/detail.go?type=gene&acc=1244
|
||
|
ABCC2
|
Rattus norvegicus (Norway rat)
|
Dexamethasone results in decreased expression of ABCC2 mRNA
|
https://ctdbase.org/detail.go?type=gene&acc=1244
|
||
|
ABCC2
|
Rattus norvegicus (Norway rat)
|
Dexamethasone results in increased expression of ABCC2 mRNA
|
https://ctdbase.org/detail.go?type=gene&acc=1244
|
||
|
ABCC2
|
Rattus norvegicus (Norway rat)
|
Dexamethasone results in increased expression of ABCC2 protein
|
https://ctdbase.org/detail.go?type=gene&acc=1244
|
||
|
ABCC2
|
Rattus norvegicus (Norway rat)
|
Testosterone inhibits the reaction [dexamethasone results in increased expression of ABCC2 mrna]
|
https://ctdbase.org/detail.go?type=gene&acc=1244
|
||
|
ABCC2
|
Rattus norvegicus (Norway rat)
|
ABCC2 protein affects the abundance of 4-(N-methyl-N-nitrosamino)-1-(3-pyridyl)-1-butanone metabolite
|
https://ctdbase.org/detail.go?type=gene&acc=1244
|
||
|
ABCC2
|
Homo sapiens (human)
|
Colforsin results in increased expression of ABCC2 mRNA
|
https://ctdbase.org/detail.go?type=gene&acc=1244
|
||
|
ABCC2
|
Homo sapiens (human)
|
Colforsin results in increased expression of ABCC2 protein
|
https://ctdbase.org/detail.go?type=gene&acc=1244
|
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