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Interactions between compounds and specific gene/protein targets.
| BIMP_ID | Target Name | Gene | Organism | Action | Source URL |
|---|---|---|---|---|---|
|
ABCC2
|
Mus musculus (house mouse)
|
ABCC2 protein affects the susceptibility to hypaconitine
|
https://ctdbase.org/detail.go?type=gene&acc=1244
|
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|
ABCC2
|
Homo sapiens (human)
|
ABCC2 protein results in increased transport of ginsenoside re
|
https://ctdbase.org/detail.go?type=gene&acc=1244
|
||
|
ABCC2
|
Rattus norvegicus (Norway rat)
|
[isoniazid co-treated with rifampin co-treated with pyrazinamide co-treated with ethambutol] affects the expression of ABCC2 protein
|
https://ctdbase.org/detail.go?type=gene&acc=1244
|
||
|
ABCC2
|
Rattus norvegicus (Norway rat)
|
Isoniazid results in decreased expression of ABCC2 mRNA
|
https://ctdbase.org/detail.go?type=gene&acc=1244
|
||
|
ABCC2
|
Rattus norvegicus (Norway rat)
|
[lipopolysaccharides co-treated with isoniazid] results in decreased expression of ABCC2 mRNA
|
https://ctdbase.org/detail.go?type=gene&acc=1244
|
||
|
ABCC2
|
Mus musculus (house mouse)
|
[methionine deficiency co-treated with choline deficiency] results in increased expression of ABCC2 mrna|[lep gene mutant form co-treated with methionine deficiency co-treated with choline deficiency] results in increased expression of ABCC2 mRNA
|
https://ctdbase.org/detail.go?type=gene&acc=1244
|
||
|
ABCC2
|
Rattus norvegicus (Norway rat)
|
[methionine deficiency co-treated with choline deficiency] results in increased expression of ABCC2 protein
|
https://ctdbase.org/detail.go?type=gene&acc=1244
|
||
|
ABCC2
|
Homo sapiens (human)
|
Clotrimazole results in increased expression of ABCC2 mrna|clotrimazole results in increased expression of ABCC2 protein
|
https://ctdbase.org/detail.go?type=gene&acc=1244
|
||
|
ABCC2
|
Homo sapiens (human)
|
ABCC2 protein affects the export of estrone sulfate
|
https://ctdbase.org/detail.go?type=gene&acc=1244
|
||
|
ABCC2
|
Rattus norvegicus (Norway rat)
|
Estrone sulfate results in increased activity of ABCC2 protein modified form|estrone sulfate results in increased activity of ABCC2 protein
|
https://ctdbase.org/detail.go?type=gene&acc=1244
|
||
|
ABCC2
|
Homo sapiens (human)
|
Diclofenac results in decreased activity of ABCC2 protein
|
https://ctdbase.org/detail.go?type=gene&acc=1244
|
||
|
ABCC2
|
Homo sapiens (human)
|
Diclofenac results in increased expression of ABCC2 mRNA
|
https://ctdbase.org/detail.go?type=gene&acc=1244
|
||
|
ABCC2
|
Rattus norvegicus (Norway rat)
|
ABCC2 protein results in increased transport of and results in increased metabolism of and results in increased susceptibility to diclofenac
|
https://ctdbase.org/detail.go?type=gene&acc=1244
|
||
|
ABCC2
|
Homo sapiens (human)
|
Indomethacin inhibits the reaction [[5-methoxypsoralen results in decreased activity of ABCC2 protein] which results in decreased export of and results in increased abundance of daunorubicin]|[methoxsalen results in decreased activity of ABCC2 protein] which results in decreased export of and results in increased abundance of daunorubicin|indomethacin inhibits the reaction [[methoxsalen results in decreased activity of ABCC2 protein] which results in decreased export of and results in increased abundance of daunorubicin]|[5-methoxypsoralen results in decreased activity of ABCC2 protein] which results in decreased export of and results in increased abundance of daunorubicin
|
https://ctdbase.org/detail.go?type=gene&acc=1244
|
||
|
ABCC2
|
Homo sapiens (human)
|
ABCC2 affects the susceptibility to daunorubicin
|
https://ctdbase.org/detail.go?type=gene&acc=1244
|
||
|
ABCC2
|
Mus musculus (house mouse)
|
Clofibrate results in increased expression of ABCC2 mRNA
|
https://ctdbase.org/detail.go?type=gene&acc=1244
|
||
|
ABCC2
|
Rattus norvegicus (Norway rat)
|
Clofibrate results in decreased expression of ABCC2 mRNA
|
https://ctdbase.org/detail.go?type=gene&acc=1244
|
||
|
ABCC2
|
Rattus norvegicus (Norway rat)
|
Geraniol inhibits the reaction [fructose results in decreased expression of ABCC2 mrna]|fructose results in decreased expression of ABCC2 protein|ascorbic acid inhibits the reaction [fructose results in decreased expression of ABCC2 protein]|geraniol inhibits the reaction [fructose results in decreased expression of ABCC2 protein]|fructose results in decreased expression of ABCC2 mrna|ascorbic acid inhibits the reaction [fructose results in decreased expression of ABCC2 mrna]
|
https://ctdbase.org/detail.go?type=gene&acc=1244
|
||
|
ABCC2
|
Homo sapiens (human)
|
|
https://www.dgidb.org/genes/hgnc:53
|
||
|
ABCC2
|
Mus musculus (house mouse)
|
Ciprofloxacin results in decreased expression of ABCC2 mRNA
|
https://ctdbase.org/detail.go?type=gene&acc=1244
|
||
|
ABCC2
|
Danio rerio (zebrafish)
|
Valproic acid affects the expression of ABCC2 mRNA
|
https://ctdbase.org/detail.go?type=gene&acc=1244
|
||
|
ABCC2
|
Homo sapiens (human)
|
Valproic acid results in increased expression of ABCC2 protein|valproic acid results in decreased expression of ABCC2 mrna|valproic acid results in increased methylation of ABCC2 gene
|
https://ctdbase.org/detail.go?type=gene&acc=1244
|
||
|
ABCC2
|
Homo sapiens (human)
|
Valproic acid results in increased expression of ABCC2 mRNA
|
https://ctdbase.org/detail.go?type=gene&acc=1244
|
||
|
ABCC2
|
Mus musculus (house mouse)
|
Valproic acid results in increased expression of ABCC2 mRNA
|
https://ctdbase.org/detail.go?type=gene&acc=1244
|
||
|
ABCC2
|
Rattus norvegicus (Norway rat)
|
[carbon tetrachloride co-treated with valproic acid] affects the expression of ABCC2 mRNA
|
https://ctdbase.org/detail.go?type=gene&acc=1244
|
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