SCFBio, IIT Delhi
Hauz Khas, New Delhi
BIMP
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SCFBio, IIT Delhi
Interactions between compounds and specific gene/protein targets.
| BIMP_ID | Target Name | Gene | Organism | Action | Source URL |
|---|---|---|---|---|---|
|
ABCC1
|
Homo sapiens (human)
|
Caffeine results in increased phosphorylation of ABCC1 protein
|
https://ctdbase.org/detail.go?type=gene&acc=4363
|
||
|
ABCC1
|
Homo sapiens (human)
|
|
https://www.dgidb.org/genes/hgnc:51
|
||
|
ABCC1
|
Homo sapiens (human)
|
Chloroquine results in decreased expression of ABCC1 protein|chloroquine results in decreased expression of ABCC1 mRNA
|
https://ctdbase.org/detail.go?type=gene&acc=4363
|
||
|
ABCC1
|
Homo sapiens (human)
|
Butyraldehyde results in decreased expression of ABCC1 mRNA
|
https://ctdbase.org/detail.go?type=gene&acc=4363
|
||
|
ABCC1
|
Homo sapiens (human)
|
5-methoxypsoralen results in increased expression of ABCC1 mRNA
|
https://ctdbase.org/detail.go?type=gene&acc=4363
|
||
|
ABCC1
|
Homo sapiens (human)
|
[MYCN protein affects the expression of ABCC1 mrna] which affects the susceptibility to doxorubicin
|
https://ctdbase.org/detail.go?type=gene&acc=4363
|
||
|
ABCC1
|
Homo sapiens (human)
|
[[resveratrol co-treated with doxorubicin] results in decreased expression of ABCC1 mrna] which results in increased uptake of doxorubicin|[resveratrol co-treated with doxorubicin] results in decreased expression of ABCC1 mRNA
|
https://ctdbase.org/detail.go?type=gene&acc=4363
|
||
|
ABCC1
|
Homo sapiens (human)
|
Verapamil inhibits the reaction [ABCC1 protein results in decreased susceptibility to doxorubicin]
|
https://ctdbase.org/detail.go?type=gene&acc=4363
|
||
|
ABCC1
|
Homo sapiens (human)
|
Verlukast inhibits the reaction [ABCC1 protein results in decreased susceptibility to doxorubicin]
|
https://ctdbase.org/detail.go?type=gene&acc=4363
|
||
|
ABCC1
|
Homo sapiens (human)
|
ABCC1 affects the susceptibility to doxorubicin
|
https://ctdbase.org/detail.go?type=gene&acc=4363
|
||
|
ABCC1
|
Homo sapiens (human)
|
ABCC1 mRNA affects the susceptibility to doxorubicin|[resveratrol results in decreased expression of ABCC1] which results in increased uptake of doxorubicin
|
https://ctdbase.org/detail.go?type=gene&acc=4363
|
||
|
ABCC1
|
Homo sapiens (human)
|
ABCC1 protein affects the susceptibility to doxorubicin
|
https://ctdbase.org/detail.go?type=gene&acc=4363
|
||
|
ABCC1
|
Homo sapiens (human)
|
ABCC1 protein mutant form affects the transport of doxorubicin|abcc1 protein affects the transport of doxorubicin
|
https://ctdbase.org/detail.go?type=gene&acc=4363
|
||
|
ABCC1
|
Homo sapiens (human)
|
ABCC1 protein results in decreased susceptibility to doxorubicin
|
https://ctdbase.org/detail.go?type=gene&acc=4363
|
||
|
ABCC1
|
Mus musculus (house mouse)
|
ABCC1 gene mutant form promotes the reaction [doxorubicin results in increased expression of GCLC protein]|doxorubicin promotes the reaction [ABCC1 gene mutant form results in decreased expression of SOD3 mrna]|abcc1 gene mutant form promotes the reaction [doxorubicin results in increased expression of GCLM protein]|abcc1 gene mutant form results in increased susceptibility to doxorubicin|abcc1 gene mutant form promotes the reaction [doxorubicin results in increased cleavage of PARP1 protein]|doxorubicin promotes the reaction [ABCC1 gene mutant form results in decreased expression of SOD3 protein]|abcc1 gene results in decreased susceptibility to doxorubicin|abcc1 gene mutant form promotes the reaction [doxorubicin results in increased cleavage of CASP3 protein]
|
https://ctdbase.org/detail.go?type=gene&acc=4363
|
||
|
ABCC1
|
Mus musculus (house mouse)
|
ABCC1 protein results in decreased susceptibility to doxorubicin
|
https://ctdbase.org/detail.go?type=gene&acc=4363
|
||
|
ABCC1
|
Mus musculus (house mouse)
|
ABCC1 results in decreased susceptibility to doxorubicin
|
https://ctdbase.org/detail.go?type=gene&acc=4363
|
||
|
ABCC1
|
Mus musculus (house mouse)
|
[copper (N-2-hydroxyacetophenone)glycinate results in decreased expression of ABCC1 protein] which results in increased susceptibility to doxorubicin
|
https://ctdbase.org/detail.go?type=gene&acc=4363
|
||
|
ABCC1
|
Mus musculus (house mouse)
|
Doxorubicin results in increased expression of ABCC1 mrna|doxorubicin inhibits the reaction [lovastatin results in increased expression of ABCC1 mrna]
|
https://ctdbase.org/detail.go?type=gene&acc=4363
|
||
|
ABCC1
|
Rattus norvegicus (Norway rat)
|
ABCC1 protein results in decreased susceptibility to doxorubicin
|
https://ctdbase.org/detail.go?type=gene&acc=4363
|
||
|
ABCC1
|
Homo sapiens (human)
|
ABCC1 affects the susceptibility to doxorubicin
|
https://ctdbase.org/detail.go?type=gene&acc=4363
|
||
|
ABCC1
|
Homo sapiens (human)
|
ABCC1 protein results in increased susceptibility to doxorubicin|buthionine sulfoximine ethyl ester promotes the reaction [ABCC1 protein results in increased susceptibility to doxorubicin]
|
https://ctdbase.org/detail.go?type=gene&acc=4363
|
||
|
ABCC1
|
Homo sapiens (human)
|
ABCC1 results in decreased susceptibility to doxorubicin
|
https://ctdbase.org/detail.go?type=gene&acc=4363
|
||
|
ABCC1
|
Homo sapiens (human)
|
Ursodeoxycholic acid inhibits the reaction [ABCC1 protein results in increased export of 2',7'-bis-(carboxypropyl)-5(6)-carboxyfluorescein]
|
https://ctdbase.org/detail.go?type=gene&acc=4363
|
||
|
ABCC1
|
Rattus
|
Ursodeoxycholic acid affects the expression of ABCC1 mRNA
|
https://ctdbase.org/detail.go?type=gene&acc=4363
|
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