Molecular Targets : Dataset Browser

BIMP_ID	Target Name	Gene	Organism	Action	Source URL
BIMP073059	ABCC1	ABCC1	Homo sapiens (human)	Verlukast inhibits the reaction [ABCC1 protein results in decreased susceptibility to etoposide]	https://ctdbase.org/detail.go?type=gene&acc=4363
BIMP073059	ABCC1	ABCC1	Macaca fascicularis (crab-eating macaque)	ABCC1 protein results in decreased susceptibility to etoposide	https://ctdbase.org/detail.go?type=gene&acc=4363
BIMP073059	ABCC1	ABCC1	Mus musculus (house mouse)	Verapamil inhibits the reaction [ABCC1 protein results in decreased uptake of etoposide]\|etoposide results in increased expression of ABCC1 mrna\|abcc1 protein results in decreased uptake of etoposide\|glucose inhibits the reaction [sodium azide inhibits the reaction [ABCC1 protein results in decreased uptake of etoposide]]\|sodium azide inhibits the reaction [ABCC1 protein results in decreased uptake of etoposide]\|verapamil inhibits the reaction [ABCC1 protein results in decreased susceptibility to etoposide]\|abcc1 protein results in decreased susceptibility to etoposide	https://ctdbase.org/detail.go?type=gene&acc=4363
BIMP073059	ABCC1	ABCC1	Mus musculus (house mouse)	ABCC1 results in decreased susceptibility to etoposide	https://ctdbase.org/detail.go?type=gene&acc=4363
BIMP073059	ABCC1	ABCC1	Homo sapiens (human)	Verapamil inhibits the reaction [[ABCC1 protein co-treated with MGMT protein mutant form] results in decreased susceptibility to etoposide]\|[abcc1 protein co-treated with MGMT protein mutant form] results in decreased susceptibility to etoposide	https://ctdbase.org/detail.go?type=gene&acc=4363
BIMP072708	ABCC1	ABCC1	Homo sapiens (human)	Sodium dodecyl sulfate inhibits the reaction [ABCC1 protein results in increased export of 2',7'-bis-(carboxypropyl)-5(6)-carboxyfluorescein]	https://ctdbase.org/detail.go?type=gene&acc=4363
BIMP068482	ABCC1	ABCC1	Danio rerio (zebrafish)	[ethanol co-treated with benzo(a)pyrene] results in increased expression of ABCC1 mRNA	https://ctdbase.org/detail.go?type=gene&acc=4363
BIMP068482	ABCC1	ABCC1	Homo sapiens (human)	Benzo(a)pyrene affects the methylation of ABCC1 intron	https://ctdbase.org/detail.go?type=gene&acc=4363
BIMP068482	ABCC1	ABCC1	Homo sapiens (human)	Benzo(a)pyrene results in increased expression of ABCC1 mRNA	https://ctdbase.org/detail.go?type=gene&acc=4363
BIMP068482	ABCC1	ABCC1	Homo sapiens (human)	Benzo(a)pyrene results in increased methylation of ABCC1 3' UTR	https://ctdbase.org/detail.go?type=gene&acc=4363
BIMP070301	ABCC1	ABCC1	Bos taurus (cattle)	Verapamil results in decreased activity of ABCC1 protein	https://ctdbase.org/detail.go?type=gene&acc=4363
BIMP070301	ABCC1	ABCC1	Homo sapiens (human)	Verapamil affects the activity of ABCC1 protein	https://ctdbase.org/detail.go?type=gene&acc=4363
BIMP070301	ABCC1	ABCC1	Homo sapiens (human)	Verapamil inhibits the reaction [ABCC1 protein affects the export of 5-carboxyfluorescein diacetate]	https://ctdbase.org/detail.go?type=gene&acc=4363
BIMP070301	ABCC1	ABCC1	Homo sapiens (human)	Verapamil inhibits the reaction [ABCC1 protein affects the export of daunorubicin]\|verapamil promotes the reaction [ABCC1 protein affects the export of glutathione]	https://ctdbase.org/detail.go?type=gene&acc=4363
BIMP070301	ABCC1	ABCC1	Homo sapiens (human)	Verapamil inhibits the reaction [ABCC1 protein results in decreased susceptibility to doxorubicin]\|verapamil inhibits the reaction [ABCC1 protein results in decreased susceptibility to vincristine]	https://ctdbase.org/detail.go?type=gene&acc=4363
BIMP070301	ABCC1	ABCC1	Homo sapiens (human)	Verapamil inhibits the reaction [ABCC1 protein results in increased export of 2',7'-bis-(carboxypropyl)-5(6)-carboxyfluorescein]	https://ctdbase.org/detail.go?type=gene&acc=4363
BIMP070301	ABCC1	ABCC1	Homo sapiens (human)	Verapamil promotes the reaction [ABCC1 protein affects the transport of glutathione]	https://ctdbase.org/detail.go?type=gene&acc=4363
BIMP070301	ABCC1	ABCC1	Homo sapiens (human)	Verapamil promotes the reaction [ABCC1 protein results in increased uptake of glutathione]	https://ctdbase.org/detail.go?type=gene&acc=4363
BIMP070301	ABCC1	ABCC1	Homo sapiens (human)	Verapamil results in decreased activity of ABCC1 protein	https://ctdbase.org/detail.go?type=gene&acc=4363
BIMP070301	ABCC1	ABCC1	Mus musculus (house mouse)	Verapamil inhibits the reaction [ABCC1 protein results in decreased uptake of daunorubicin]\|verapamil inhibits the reaction [ABCC1 protein results in decreased susceptibility to etoposide]\|verapamil inhibits the reaction [ABCC1 protein results in decreased uptake of etoposide]	https://ctdbase.org/detail.go?type=gene&acc=4363
BIMP070301	ABCC1	ABCC1	Homo sapiens (human)	Verapamil inhibits the reaction [ABCC1 protein results in increased export of calcein AM]\|ABCC1 protein results in increased susceptibility to verapamil\|abcc1 protein promotes the reaction [verapamil results in decreased abundance of glutathione]	https://ctdbase.org/detail.go?type=gene&acc=4363
BIMP070301	ABCC1	ABCC1	Homo sapiens (human)	Verapamil inhibits the reaction [[ABCC1 protein co-treated with MGMT protein mutant form] results in decreased susceptibility to etoposide]	https://ctdbase.org/detail.go?type=gene&acc=4363
BIMP070822	ABCC1	ABCC1	Homo sapiens (human)	Cannabinol results in decreased activity of ABCC1 protein	https://ctdbase.org/detail.go?type=gene&acc=4363
BIMP069148	ABCC1	ABCC1	Homo sapiens (human)	ABCC1 protein results in decreased susceptibility to camptothecin analog	https://ctdbase.org/detail.go?type=gene&acc=4363
BIMP069148	ABCC1	ABCC1	Homo sapiens (human)	Camptothecin inhibits the reaction [ABCC1 results in decreased susceptibility to daunorubicin]	https://ctdbase.org/detail.go?type=gene&acc=4363

BIMP073059

ABCC1

Homo sapiens (human)

Verlukast inhibits the reaction [ABCC1 protein results in decreased susceptibility to etoposide]