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SCFBio, IIT Delhi Hauz Khas, New Delhi

Molecular Targets

Interactions between compounds and specific gene/protein targets.

Total Rows 750,454
Pages 30,019
BIMP_ID Target Name Gene Organism Action Source URL
ABCC1
Homo sapiens (human)
Indomethacin results in decreased expression of ABCC1 mRNA
https://ctdbase.org/detail.go?type=gene&acc=4363
ABCC1
Mus musculus (house mouse)
Indomethacin results in decreased activity of ABCC1 protein
https://ctdbase.org/detail.go?type=gene&acc=4363
ABCC1
Oryctolagus cuniculus (rabbit)
Indomethacin inhibits the reaction [ABCC1 protein results in increased export of fluorescein]|indomethacin inhibits the reaction [ABCC1 protein results in increased export of vincristine]
https://ctdbase.org/detail.go?type=gene&acc=4363
ABCC1
Rattus norvegicus (Norway rat)
Indomethacin results in decreased activity of ABCC1 protein|[indomethacin results in decreased activity of ABCC1 protein] which results in increased uptake of vincristine
https://ctdbase.org/detail.go?type=gene&acc=4363
ABCC1
Homo sapiens (human)
Indomethacin inhibits the reaction [ABCC1 protein results in increased transport of leukotriene c4]|indomethacin inhibits the reaction [ABCC1 protein results in increased transport of eugenol]
https://ctdbase.org/detail.go?type=gene&acc=4363
ABCC1
Homo sapiens (human)
Zidovudine results in increased expression of ABCC1 mRNA
https://ctdbase.org/detail.go?type=gene&acc=4363
ABCC1
Homo sapiens (human)
[[chlorpyrifos co-treated with decamethrin co-treated with polymarcine co-treated with glyphosate] results in decreased susceptibility to temozolomide] which results in increased expression of ABCC1 mrna|[[chlorpyrifos co-treated with decamethrin co-treated with polymarcine co-treated with glyphosate] results in decreased susceptibility to fluorouracil] which results in increased expression of ABCC1 mrna|[[chlorpyrifos co-treated with decamethrin co-treated with polymarcine co-treated with glyphosate] results in decreased susceptibility to cisplatin] which results in increased expression of ABCC1 mRNA
https://ctdbase.org/detail.go?type=gene&acc=4363
ABCC1
Homo sapiens (human)
ABCC1 protein affects the susceptibility to [fluorouracil co-treated with epirubicin co-treated with cyclophosphamide]
https://ctdbase.org/detail.go?type=gene&acc=4363
ABCC1
Homo sapiens (human)
[[chlorpyrifos co-treated with decamethrin co-treated with polymarcine co-treated with glyphosate] results in decreased susceptibility to fluorouracil] which results in increased expression of ABCC1 mRNA
https://ctdbase.org/detail.go?type=gene&acc=4363
ABCC1
Homo sapiens (human)
ABCC1 protein results in increased transport of eugenol|indomethacin inhibits the reaction [ABCC1 protein results in increased transport of eugenol]
https://ctdbase.org/detail.go?type=gene&acc=4363
ABCC1
Homo sapiens (human)
ABCC1 protein results in decreased susceptibility to ethacrynic acid|gstp1 protein promotes the reaction [ABCC1 protein results in decreased susceptibility to ethacrynic acid]
https://ctdbase.org/detail.go?type=gene&acc=4363
ABCC1
Homo sapiens (human)
Glyburide results in decreased activity of ABCC1 protein
https://ctdbase.org/detail.go?type=gene&acc=4363
ABCC1
Homo sapiens (human)
Hypericin results in increased expression of ABCC1 protein
https://ctdbase.org/detail.go?type=gene&acc=4363
ABCC1
Homo sapiens (human)
https://www.dgidb.org/genes/hgnc:51
ABCC1
Rattus norvegicus (Norway rat)
Indole-3-carbinol affects the expression of ABCC1 mRNA
https://ctdbase.org/detail.go?type=gene&acc=4363
ABCC1
Rattus norvegicus (Norway rat)
Indole-3-carbinol results in increased expression of ABCC1 mRNA
https://ctdbase.org/detail.go?type=gene&acc=4363
ABCC1
Bos taurus (cattle)
ABCC1 protein results in decreased susceptibility to etoposide
https://ctdbase.org/detail.go?type=gene&acc=4363
ABCC1
Canis lupus familiaris (dog)
ABCC1 protein results in decreased susceptibility to etoposide
https://ctdbase.org/detail.go?type=gene&acc=4363
ABCC1
Homo sapiens (human)
ABCC1 protein affects the susceptibility to etoposide
https://ctdbase.org/detail.go?type=gene&acc=4363
ABCC1
Homo sapiens (human)
ABCC1 protein results in decreased susceptibility to etoposide
https://ctdbase.org/detail.go?type=gene&acc=4363
ABCC1
Homo sapiens (human)
ABCC1 results in decreased susceptibility to etoposide
https://ctdbase.org/detail.go?type=gene&acc=4363
ABCC1
Homo sapiens (human)
GSTP1 protein promotes the reaction [ABCC1 protein results in decreased susceptibility to etoposide]|[gclc protein co-treated with GCLM protein] promotes the reaction [ABCC1 protein results in decreased susceptibility to etoposide]
https://ctdbase.org/detail.go?type=gene&acc=4363
ABCC1
Homo sapiens (human)
Silymarin inhibits the reaction [ABCC1 protein results in decreased susceptibility to etoposide]|naringenin inhibits the reaction [ABCC1 protein results in decreased susceptibility to etoposide]|hesperetin inhibits the reaction [ABCC1 protein results in decreased susceptibility to etoposide]|resveratrol inhibits the reaction [ABCC1 protein results in decreased susceptibility to etoposide]
https://ctdbase.org/detail.go?type=gene&acc=4363
ABCC1
Homo sapiens (human)
[MYCN protein affects the expression of ABCC1 mrna] which affects the susceptibility to etoposide
https://ctdbase.org/detail.go?type=gene&acc=4363
ABCC1
Homo sapiens (human)
Tocopherols inhibits the reaction [ABCC1 protein affects the export of etoposide]
https://ctdbase.org/detail.go?type=gene&acc=4363
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