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SCFBio, IIT Delhi Hauz Khas, New Delhi

Molecular Targets

Interactions between compounds and specific gene/protein targets.

Total Rows 750,454
Pages 30,019
BIMP_ID Target Name Gene Organism Action Source URL
ABCC1
Rattus norvegicus (Norway rat)
Ursodeoxycholic acid results in increased expression of ABCC1 mRNA
https://ctdbase.org/detail.go?type=gene&acc=4363
ABCC1
Homo sapiens (human)
Epigallocatechin gallate affects the reaction [doxorubicin affects the expression of ABCC1 protein]
https://ctdbase.org/detail.go?type=gene&acc=4363
ABCC1
Homo sapiens (human)
[estradiol results in increased expression of ABCC1 mrna] which results in increased susceptibility to doxorubicin
https://ctdbase.org/detail.go?type=gene&acc=4363
ABCC1
Homo sapiens (human)
Acetylcysteine promotes the reaction [ABCC1 protein results in decreased susceptibility to doxorubicin]|buthionine sulfoximine analog inhibits the reaction [acetylcysteine promotes the reaction [ABCC1 protein results in decreased susceptibility to doxorubicin]]
https://ctdbase.org/detail.go?type=gene&acc=4363
ABCC1
Homo sapiens (human)
Coumarin results in decreased phosphorylation of ABCC1 protein
https://ctdbase.org/detail.go?type=gene&acc=4363
ABCC1
Macaca fascicularis (crab-eating macaque)
ABCC1 protein results in decreased susceptibility to doxorubicin
https://ctdbase.org/detail.go?type=gene&acc=4363
ABCC1
Homo sapiens (human)
Haloperidol inhibits the reaction [ABCC1 protein results in decreased susceptibility to doxorubicin]
https://ctdbase.org/detail.go?type=gene&acc=4363
ABCC1
Homo sapiens (human)
Heparin affects the reaction [ABCC1 protein affects the transport of doxorubicin]
https://ctdbase.org/detail.go?type=gene&acc=4363
ABCC1
Homo sapiens (human)
Indomethacin inhibits the reaction [ABCC1 protein results in decreased susceptibility to doxorubicin]
https://ctdbase.org/detail.go?type=gene&acc=4363
ABCC1
Homo sapiens (human)
GCLC protein inhibits the reaction [ABCC1 protein results in decreased susceptibility to doxorubicin]
https://ctdbase.org/detail.go?type=gene&acc=4363
ABCC1
Homo sapiens (human)
[glycyrrhetinic acid affects the activity of ABCC1 protein] which affects the susceptibility to doxorubicin
https://ctdbase.org/detail.go?type=gene&acc=4363
ABCC1
Homo sapiens (human)
Doxorubicin results in increased expression of ABCC1 protein|doxorubicin promotes the reaction [JUN protein binds to ABCC1 promoter]
https://ctdbase.org/detail.go?type=gene&acc=4363
ABCC1
Homo sapiens (human)
[doxorubicin results in decreased expression of ABCC1 mrna] which results in increased susceptibility to indomethacin
https://ctdbase.org/detail.go?type=gene&acc=4363
ABCC1
Homo sapiens (human)
Doxorubicin results in increased expression of ABCC1 mRNA
https://ctdbase.org/detail.go?type=gene&acc=4363
ABCC1
Homo sapiens (human)
[bortezomib co-treated with doxorubicin] results in decreased expression of ABCC1 protein|[pentoxifylline co-treated with doxorubicin] results in decreased expression of ABCC1 protein|doxorubicin results in decreased expression of ABCC1 protein
https://ctdbase.org/detail.go?type=gene&acc=4363
ABCC1
Homo sapiens (human)
HIF1A protein affects the reaction [[doxorubicin co-treated with IL6 protein] results in increased expression of ABCC1 protein]|[doxorubicin co-treated with IL6 protein] results in increased expression of ABCC1 protein
https://ctdbase.org/detail.go?type=gene&acc=4363
ABCC1
Homo sapiens (human)
Doxorubicin inhibits the reaction [ABCC1 protein affects the transport of vincristine]
https://ctdbase.org/detail.go?type=gene&acc=4363
ABCC1
Homo sapiens (human)
ABCC1 protein results in decreased susceptibility to resveratrol|resveratrol inhibits the reaction [ABCC1 protein results in increased export of S-(2,4-dinitrophenyl)glutathione]|resveratrol promotes the reaction [ABCC1 protein results in increased hydrolysis of adenosine triphosphate]|resveratrol inhibits the reaction [ABCC1 protein results in decreased susceptibility to etoposide]
https://ctdbase.org/detail.go?type=gene&acc=4363
ABCC1
Homo sapiens (human)
[[resveratrol co-treated with doxorubicin] results in decreased expression of ABCC1 mrna] which results in increased uptake of doxorubicin|[resveratrol co-treated with doxorubicin] results in decreased expression of ABCC1 mRNA
https://ctdbase.org/detail.go?type=gene&acc=4363
ABCC1
Homo sapiens (human)
Resveratrol results in decreased expression of ABCC1
https://ctdbase.org/detail.go?type=gene&acc=4363
ABCC1
Homo sapiens (human)
[resveratrol results in decreased expression of ABCC1] which results in increased uptake of doxorubicin
https://ctdbase.org/detail.go?type=gene&acc=4363
ABCC1
Homo sapiens (human)
https://www.dgidb.org/genes/hgnc:51
ABCC1
Homo sapiens (human)
https://www.dgidb.org/genes/hgnc:51
ABCC1
Homo sapiens (human)
N-(2-cyclohexyloxy-4-nitrophenyl)methanesulfonamide results in increased expression of ABCC1 mRNA
https://ctdbase.org/detail.go?type=gene&acc=4363
ABCC1
Homo sapiens (human)
https://www.dgidb.org/genes/hgnc:51
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