SCFBio, IIT Delhi
Hauz Khas, New Delhi
BIMP
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SCFBio, IIT Delhi
Interactions between compounds and specific gene/protein targets.
| BIMP_ID | Target Name | Gene | Organism | Action | Source URL |
|---|---|---|---|---|---|
|
ABCC1
|
Homo sapiens (human)
|
Quercetin results in increased phosphorylation of ABCC1 protein
|
https://ctdbase.org/detail.go?type=gene&acc=4363
|
||
|
ABCC1
|
Mus musculus (house mouse)
|
Quercetin inhibits the reaction [lipopolysaccharides results in increased expression of ABCC1 mrna]|quercetin results in increased expression of ABCC1 mRNA
|
https://ctdbase.org/detail.go?type=gene&acc=4363
|
||
|
ABCC1
|
Homo sapiens (human)
|
Benzyloxycarbonylleucyl-leucyl-leucine aldehyde results in decreased degradation of and results in increased expression of ABCC1 protein mutant form
|
https://ctdbase.org/detail.go?type=gene&acc=4363
|
||
|
ABCC1
|
Mus musculus (house mouse)
|
Dexamethasone inhibits the reaction [lipopolysaccharides results in increased expression of ABCC1 mrna]|dexamethasone results in increased expression of ABCC1 mRNA
|
https://ctdbase.org/detail.go?type=gene&acc=4363
|
||
|
ABCC1
|
Rattus norvegicus (Norway rat)
|
Dexamethasone inhibits the reaction [lipopolysaccharides results in increased expression of ABCC1 mrna]
|
https://ctdbase.org/detail.go?type=gene&acc=4363
|
||
|
ABCC1
|
Gallus gallus (chicken)
|
Estradiol results in decreased expression of ABCC1 mrna|estrogens results in decreased expression of ABCC1 mRNA
|
https://ctdbase.org/detail.go?type=gene&acc=4363
|
||
|
ABCC1
|
Homo sapiens (human)
|
Estradiol results in increased expression of ABCC1 mRNA
|
https://ctdbase.org/detail.go?type=gene&acc=4363
|
||
|
ABCC1
|
Homo sapiens (human)
|
[estradiol results in increased expression of ABCC1 mrna] which results in increased susceptibility to cisplatin|[estradiol results in increased expression of ABCC1 mrna] which results in increased susceptibility to doxorubicin
|
https://ctdbase.org/detail.go?type=gene&acc=4363
|
||
|
ABCC1
|
Homo sapiens (human)
|
ABCC1 protein results in decreased susceptibility to mitomycin
|
https://ctdbase.org/detail.go?type=gene&acc=4363
|
||
|
ABCC1
|
Homo sapiens (human)
|
[4-(2-(5,6,7,8-tetrahydro-5,5,8,8-tetramethyl-2-naphthalenyl)-1-propenyl)benzoic acid co-treated with chir 99021 co-treated with 3-(4-pyridyl)-1H-indole co-treated with hydrocortisone co-treated with EGF protein co-treated with FGF9 protein] results in decreased expression of ABCC1 mRNA
|
https://ctdbase.org/detail.go?type=gene&acc=4363
|
||
|
ABCC1
|
Homo sapiens (human)
|
Estradiol results in increased expression of ABCC1 protein
|
https://ctdbase.org/detail.go?type=gene&acc=4363
|
||
|
ABCC1
|
Rattus norvegicus (Norway rat)
|
Estradiol results in decreased expression of ABCC1 mRNA
|
https://ctdbase.org/detail.go?type=gene&acc=4363
|
||
|
ABCC1
|
Homo sapiens (human)
|
Acetylcysteine inhibits the reaction [3',4',7-trihydroxyisoflavone results in decreased expression of ABCC1 mrna]
|
https://ctdbase.org/detail.go?type=gene&acc=4363
|
||
|
ABCC1
|
Homo sapiens (human)
|
Acetylcysteine inhibits the reaction [formononetin results in decreased expression of ABCC1 mrna]
|
https://ctdbase.org/detail.go?type=gene&acc=4363
|
||
|
ABCC1
|
Homo sapiens (human)
|
Acetylcysteine inhibits the reaction [sulindac results in increased expression of ABCC1 protein]
|
https://ctdbase.org/detail.go?type=gene&acc=4363
|
||
|
ABCC1
|
Homo sapiens (human)
|
Acetylcysteine promotes the reaction [ABCC1 protein results in decreased susceptibility to doxorubicin]|buthionine sulfoximine analog inhibits the reaction [acetylcysteine promotes the reaction [ABCC1 protein results in decreased susceptibility to doxorubicin]]
|
https://ctdbase.org/detail.go?type=gene&acc=4363
|
||
|
ABCC1
|
Danio rerio (zebrafish)
|
[alpha-naphthoflavone co-treated with cadmium sulfate] results in decreased expression of ABCC1 mrna|alpha-naphthoflavone results in increased expression of ABCC1 mRNA
|
https://ctdbase.org/detail.go?type=gene&acc=4363
|
||
|
ABCC1
|
Homo sapiens (human)
|
Allyl sulfide results in decreased expression of ABCC1 mRNA
|
https://ctdbase.org/detail.go?type=gene&acc=4363
|
||
|
ABCC1
|
Danio rerio (zebrafish)
|
Glutathione affects the reaction [arsenic affects the activity of ABCC1 protein]|glutathione promotes the reaction [arsenic results in decreased expression of ABCC1 mrna]
|
https://ctdbase.org/detail.go?type=gene&acc=4363
|
||
|
ABCC1
|
Homo sapiens (human)
|
ABCC1 protein affects the export of glutathione|pak 104P promotes the reaction [ABCC1 protein affects the export of glutathione]|verapamil promotes the reaction [ABCC1 protein affects the export of glutathione]
|
https://ctdbase.org/detail.go?type=gene&acc=4363
|
||
|
ABCC1
|
Homo sapiens (human)
|
ABCC1 protein affects the reaction [chrysin results in increased transport of glutathione]
|
https://ctdbase.org/detail.go?type=gene&acc=4363
|
||
|
ABCC1
|
Homo sapiens (human)
|
ABCC1 protein affects the transport of [arsenite co-treated with glutathione]
|
https://ctdbase.org/detail.go?type=gene&acc=4363
|
||
|
ABCC1
|
Homo sapiens (human)
|
Verapamil promotes the reaction [ABCC1 protein affects the transport of glutathione]|abcc1 protein affects the transport of glutathione
|
https://ctdbase.org/detail.go?type=gene&acc=4363
|
||
|
ABCC1
|
Homo sapiens (human)
|
ABCC1 protein affects the transport of glutathione analog
|
https://ctdbase.org/detail.go?type=gene&acc=4363
|
||
|
ABCC1
|
Homo sapiens (human)
|
Buthionine sulfoximine ethyl ester promotes the reaction [ABCC1 protein results in increased export of glutathione]|gclc protein inhibits the reaction [buthionine sulfoximine ethyl ester promotes the reaction [ABCC1 protein results in increased export of glutathione]]|abcc1 protein results in increased export of glutathione
|
https://ctdbase.org/detail.go?type=gene&acc=4363
|
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