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Interactions between compounds and specific gene/protein targets.
| BIMP_ID | Target Name | Gene | Organism | Action | Source URL |
|---|---|---|---|---|---|
|
ABCC1
|
Homo sapiens (human)
|
Probenecid results in decreased activity of ABCC1 protein
|
https://ctdbase.org/detail.go?type=gene&acc=4363
|
||
|
ABCC1
|
Homo sapiens (human)
|
[probenecid results in decreased activity of ABCC1 protein] which results in decreased export of 10-nitro-oleic acid metabolite
|
https://ctdbase.org/detail.go?type=gene&acc=4363
|
||
|
ABCC1
|
Mus musculus (house mouse)
|
Probenecid results in decreased activity of ABCC1 protein
|
https://ctdbase.org/detail.go?type=gene&acc=4363
|
||
|
ABCC1
|
Oryctolagus cuniculus (rabbit)
|
Probenecid inhibits the reaction [ABCC1 protein results in increased export of leukotriene c4]|probenecid inhibits the reaction [ABCC1 protein results in increased export of fluorescein]|probenecid inhibits the reaction [ABCC1 protein results in increased export of vincristine]
|
https://ctdbase.org/detail.go?type=gene&acc=4363
|
||
|
ABCC1
|
Rattus norvegicus (Norway rat)
|
[probenecid results in decreased activity of ABCC1 protein] which results in increased uptake of vincristine|probenecid results in decreased activity of ABCC1 protein
|
https://ctdbase.org/detail.go?type=gene&acc=4363
|
||
|
ABCC1
|
Homo sapiens (human)
|
Probenecid results in decreased activity of ABCC1 protein
|
https://ctdbase.org/detail.go?type=gene&acc=4363
|
||
|
ABCC1
|
Homo sapiens (human)
|
Glutathione promotes the reaction [ABCC1 protein affects the transport of bilirubin]|adenosine triphosphate promotes the reaction [ABCC1 protein affects the transport of bilirubin]|verlukast inhibits the reaction [ABCC1 protein affects the transport of bilirubin]|abcc1 protein affects the transport of bilirubin|bilirubin inhibits the reaction [ABCC1 protein affects the transport of leukotriene C4]
|
https://ctdbase.org/detail.go?type=gene&acc=4363
|
||
|
ABCC1
|
Homo sapiens (human)
|
Biochanin A results in decreased activity of ABCC1 protein
|
https://ctdbase.org/detail.go?type=gene&acc=4363
|
||
|
ABCC1
|
Homo sapiens (human)
|
Formononetin results in decreased expression of ABCC1 mrna|acetylcysteine inhibits the reaction [formononetin results in decreased expression of ABCC1 mrna]|formononetin inhibits the reaction [epirubicin results in increased expression of ABCC1 mrna]
|
https://ctdbase.org/detail.go?type=gene&acc=4363
|
||
|
ABCC1
|
Homo sapiens (human)
|
Formononetin affects the activity of ABCC1 protein
|
https://ctdbase.org/detail.go?type=gene&acc=4363
|
||
|
ABCC1
|
Homo sapiens (human)
|
Apigenin inhibits the reaction [ABCC1 protein results in increased uptake of leukotriene c4]|glutathione promotes the reaction [apigenin inhibits the reaction [ABCC1 protein results in increased uptake of leukotriene c4]]|[glutathione co-treated with apigenin] affects the reaction [ABCC1 protein results in increased uptake of estradiol-17 beta-glucuronide]
|
https://ctdbase.org/detail.go?type=gene&acc=4363
|
||
|
ABCC1
|
Homo sapiens (human)
|
Apigenin promotes the reaction [ABCC1 protein results in increased uptake of glutathione]
|
https://ctdbase.org/detail.go?type=gene&acc=4363
|
||
|
ABCC1
|
Homo sapiens (human)
|
Apigenin results in decreased activity of ABCC1 protein
|
https://ctdbase.org/detail.go?type=gene&acc=4363
|
||
|
ABCC1
|
Homo sapiens (human)
|
[testosterone co-treated with calcitriol] results in increased expression of ABCC1 mrna|calcitriol results in increased expression of ABCC1 mRNA
|
https://ctdbase.org/detail.go?type=gene&acc=4363
|
||
|
ABCC1
|
Homo sapiens (human)
|
Luteolin results in decreased activity of ABCC1 protein
|
https://ctdbase.org/detail.go?type=gene&acc=4363
|
||
|
ABCC1
|
Homo sapiens (human)
|
Quercetin inhibits the reaction [ABCC1 protein results in increased export of S-(2,4-dinitrophenyl)glutathione]|quercetin inhibits the reaction [ABCC1 protein results in increased export of fluorexon]|quercetin affects the reaction [ABCC1 protein results in increased hydrolysis of adenosine triphosphate]|abcc1 protein results in increased susceptibility to quercetin
|
https://ctdbase.org/detail.go?type=gene&acc=4363
|
||
|
ABCC1
|
Homo sapiens (human)
|
[docetaxel co-treated with epigallocatechin gallate co-treated with quercetin] results in decreased expression of ABCC1 protein
|
https://ctdbase.org/detail.go?type=gene&acc=4363
|
||
|
ABCC1
|
Homo sapiens (human)
|
Mefloquine inhibits the reaction [quercetin results in increased activity of ABCC1 protein]|verlukast inhibits the reaction [quercetin results in increased activity of ABCC1 protein]
|
https://ctdbase.org/detail.go?type=gene&acc=4363
|
||
|
ABCC1
|
Homo sapiens (human)
|
Quercetin affects the reaction [ABCC1 protein results in increased uptake of estradiol-17 beta-glucuronide]|quercetin inhibits the reaction [ABCC1 protein results in increased uptake of leukotriene c4]|quercetin promotes the reaction [ABCC1 protein results in decreased susceptibility to vincristine]
|
https://ctdbase.org/detail.go?type=gene&acc=4363
|
||
|
ABCC1
|
Homo sapiens (human)
|
Quercetin inhibits the reaction [ABCC1 protein affects the export of S-(2,4-dinitrophenyl)glutathione]
|
https://ctdbase.org/detail.go?type=gene&acc=4363
|
||
|
ABCC1
|
Homo sapiens (human)
|
Quercetin promotes the reaction [ABCC1 protein results in increased uptake of glutathione]
|
https://ctdbase.org/detail.go?type=gene&acc=4363
|
||
|
ABCC1
|
Homo sapiens (human)
|
Quercetin results in decreased activity of ABCC1 protein
|
https://ctdbase.org/detail.go?type=gene&acc=4363
|
||
|
ABCC1
|
Homo sapiens (human)
|
Quercetin results in decreased expression of ABCC1 protein
|
https://ctdbase.org/detail.go?type=gene&acc=4363
|
||
|
ABCC1
|
Homo sapiens (human)
|
Quercetin results in increased expression of ABCC1 mRNA
|
https://ctdbase.org/detail.go?type=gene&acc=4363
|
||
|
ABCC1
|
Homo sapiens (human)
|
Quercetin results in increased expression of ABCC1 protein
|
https://ctdbase.org/detail.go?type=gene&acc=4363
|
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