Molecular Targets : Dataset Browser

BIMP_ID	Target Name	Gene	Organism	Action	Source URL
BIMP090994	ABCC1	ABCC1	Mus musculus (house mouse)	ABCC1 protein results in increased hydrolysis of adenosine triphosphate\|daunorubicin promotes the reaction [ABCC1 protein results in increased hydrolysis of adenosine triphosphate]\|vanadates inhibits the reaction [ABCC1 protein results in increased hydrolysis of adenosine triphosphate]	https://ctdbase.org/detail.go?type=gene&acc=4363
BIMP090994	ABCC1	ABCC1	Homo sapiens (human)	[adenosine triphosphate binds to ABCC1 protein] inhibits the reaction [leukotriene C4 binds to ABCC1 protein]	https://ctdbase.org/detail.go?type=gene&acc=4363
BIMP090589	ABCC1	ABCC1	Homo sapiens (human)		https://www.dgidb.org/genes/hgnc:51
BIMP082212	ABCC1	ABCC1	Homo sapiens (human)	Flavonoids analog results in decreased activity of ABCC1 protein	https://ctdbase.org/detail.go?type=gene&acc=4363
BIMP082212	ABCC1	ABCC1	Homo sapiens (human)	Flavonoids results in decreased activity of ABCC1 protein	https://ctdbase.org/detail.go?type=gene&acc=4363
BIMP082212	ABCC1	ABCC1	Homo sapiens (human)	Flavonoids results in decreased expression of ABCC1 protein\|flavonoids results in decreased expression of ABCC1 mRNA	https://ctdbase.org/detail.go?type=gene&acc=4363
BIMP082185	ABCC1	ABCC1	Homo sapiens (human)	Chrysoeriol results in decreased activity of ABCC1 protein	https://ctdbase.org/detail.go?type=gene&acc=4363
BIMP082138	ABCC1	ABCC1	Canis lupus familiaris (dog)	ABCC1 protein affects the transport of leukotriene C4	https://ctdbase.org/detail.go?type=gene&acc=4363
BIMP082138	ABCC1	ABCC1	Homo sapiens (human)	Estradiol-17 beta-glucuronide inhibits the reaction [ABCC1 protein affects the transport of leukotriene C4]\|ABCC1 protein affects the transport of leukotriene C4	https://ctdbase.org/detail.go?type=gene&acc=4363
BIMP082138	ABCC1	ABCC1	Homo sapiens (human)	ABCC1 protein mutant form results in decreased transport of leukotriene C4	https://ctdbase.org/detail.go?type=gene&acc=4363
BIMP082138	ABCC1	ABCC1	Homo sapiens (human)	Apigenin inhibits the reaction [ABCC1 protein results in increased uptake of leukotriene C4]\|ABCC1 protein results in increased uptake of leukotriene c4\|glutathione promotes the reaction [genistein affects the reaction [ABCC1 protein results in increased uptake of leukotriene c4]]\|kaempferol inhibits the reaction [ABCC1 protein results in increased uptake of leukotriene c4]\|quercetin inhibits the reaction [ABCC1 protein results in increased uptake of leukotriene c4]\|naringenin affects the reaction [ABCC1 protein results in increased uptake of leukotriene c4]\|glutathione promotes the reaction [apigenin inhibits the reaction [ABCC1 protein results in increased uptake of leukotriene c4]]\|genistein affects the reaction [ABCC1 protein results in increased uptake of leukotriene c4]\|glutathione promotes the reaction [naringenin affects the reaction [ABCC1 protein results in increased uptake of leukotriene c4]]\|myricetin inhibits the reaction [ABCC1 protein results in increased uptake of leukotriene C4]	https://ctdbase.org/detail.go?type=gene&acc=4363
BIMP082138	ABCC1	ABCC1	Homo sapiens (human)	Adenosine triphosphate promotes the reaction [ABCC1 protein affects the transport of leukotriene C4]	https://ctdbase.org/detail.go?type=gene&acc=4363
BIMP082138	ABCC1	ABCC1	Homo sapiens (human)	Bilirubin inhibits the reaction [ABCC1 protein affects the transport of leukotriene C4]	https://ctdbase.org/detail.go?type=gene&acc=4363
BIMP082138	ABCC1	ABCC1	Homo sapiens (human)	Glutathione disulfide promotes the reaction [leukotriene C4 analog binds to ABCC1 protein]\|leukotriene C4 analog binds to ABCC1 protein	https://ctdbase.org/detail.go?type=gene&acc=4363
BIMP082138	ABCC1	ABCC1	Homo sapiens (human)	[nimustine results in increased expression of ABCC1 protein] which results in increased transport of leukotriene C4	https://ctdbase.org/detail.go?type=gene&acc=4363
BIMP082138	ABCC1	ABCC1	Macaca fascicularis (crab-eating macaque)	ABCC1 protein affects the transport of leukotriene C4	https://ctdbase.org/detail.go?type=gene&acc=4363
BIMP082138	ABCC1	ABCC1	Oryctolagus cuniculus (rabbit)	Probenecid inhibits the reaction [ABCC1 protein results in increased export of leukotriene C4]\|[IL6 protein co-treated with TNF protein co-treated with IL1B protein] promotes the reaction [ABCC1 protein results in increased export of leukotriene C4]\|[IL6 protein results in increased expression of ABCC1 protein] which results in increased export of leukotriene C4\|ABCC1 protein results in increased export of leukotriene c4\|sodium azide inhibits the reaction [ABCC1 protein results in increased export of leukotriene C4]\|[TNF protein results in increased expression of ABCC1 protein] which results in increased export of leukotriene C4	https://ctdbase.org/detail.go?type=gene&acc=4363
BIMP082138	ABCC1	ABCC1	Homo sapiens (human)	ABCC1 protein binds to and results in increased transport of leukotriene C4\|[4-phenylbutyric acid results in increased activity of ABCC1 protein mutant form] which results in increased transport of leukotriene C4	https://ctdbase.org/detail.go?type=gene&acc=4363
BIMP082138	ABCC1	ABCC1	Homo sapiens (human)	ABCC1 protein results in increased transport of leukotriene c4\|indomethacin inhibits the reaction [ABCC1 protein results in increased transport of leukotriene C4]	https://ctdbase.org/detail.go?type=gene&acc=4363
BIMP082138	ABCC1	ABCC1	Homo sapiens (human)	[adenosine triphosphate binds to ABCC1 protein] inhibits the reaction [leukotriene C4 binds to ABCC1 protein]	https://ctdbase.org/detail.go?type=gene&acc=4363
BIMP081709	ABCC1	ABCC1	Homo sapiens (human)	Silymarin inhibits the reaction [ABCC1 protein results in increased export of S-(2,4-dinitrophenyl)glutathione]\|silymarin inhibits the reaction [ABCC1 protein results in increased export of fluorexon]\|silymarin inhibits the reaction [ABCC1 protein results in increased hydrolysis of adenosine triphosphate]\|silymarin inhibits the reaction [ABCC1 protein results in decreased susceptibility to etoposide]	https://ctdbase.org/detail.go?type=gene&acc=4363
BIMP080548	ABCC1	ABCC1	Homo sapiens (human)		https://www.dgidb.org/genes/hgnc:51
BIMP080548	ABCC1	ABCC1	Homo sapiens (human)	Probenecid affects the activity of ABCC1 protein	https://ctdbase.org/detail.go?type=gene&acc=4363
BIMP080548	ABCC1	ABCC1	Homo sapiens (human)	Probenecid affects the reaction [ABCC1 protein results in increased transport of valproic acid]	https://ctdbase.org/detail.go?type=gene&acc=4363
BIMP080548	ABCC1	ABCC1	Homo sapiens (human)	Probenecid inhibits the reaction [ABCC1 protein results in increased export of 2',7'-bis-(carboxypropyl)-5(6)-carboxyfluorescein]	https://ctdbase.org/detail.go?type=gene&acc=4363

BIMP090994

ABCC1

Mus musculus (house mouse)

ABCC1 protein results in increased hydrolysis of adenosine triphosphate|daunorubicin promotes the reaction [ABCC1 protein results in increased hydrolysis of adenosine triphosphate]|vanadates inhibits the reaction [ABCC1 protein results in increased hydrolysis of adenosine triphosphate]

https://ctdbase.org/detail.go?type=gene&acc=4363

BIMP090994

ABCC1

Homo sapiens (human)

[adenosine triphosphate binds to ABCC1 protein] inhibits the reaction [leukotriene C4 binds to ABCC1 protein]

https://ctdbase.org/detail.go?type=gene&acc=4363

BIMP090589

ABCC1

Homo sapiens (human)

https://www.dgidb.org/genes/hgnc:51

BIMP082212

ABCC1

Homo sapiens (human)

Flavonoids analog results in decreased activity of ABCC1 protein

https://ctdbase.org/detail.go?type=gene&acc=4363

BIMP082212

ABCC1

Homo sapiens (human)

Flavonoids results in decreased activity of ABCC1 protein

https://ctdbase.org/detail.go?type=gene&acc=4363

BIMP082212

ABCC1

Homo sapiens (human)

Flavonoids results in decreased expression of ABCC1 protein|flavonoids results in decreased expression of ABCC1 mRNA

https://ctdbase.org/detail.go?type=gene&acc=4363

BIMP082185

ABCC1

Homo sapiens (human)

Chrysoeriol results in decreased activity of ABCC1 protein

https://ctdbase.org/detail.go?type=gene&acc=4363

BIMP082138

ABCC1

Canis lupus familiaris (dog)

ABCC1 protein affects the transport of leukotriene C4

https://ctdbase.org/detail.go?type=gene&acc=4363

BIMP082138

ABCC1

Homo sapiens (human)

Estradiol-17 beta-glucuronide inhibits the reaction [ABCC1 protein affects the transport of leukotriene C4]|ABCC1 protein affects the transport of leukotriene C4

https://ctdbase.org/detail.go?type=gene&acc=4363

BIMP082138

ABCC1

Homo sapiens (human)

ABCC1 protein mutant form results in decreased transport of leukotriene C4

https://ctdbase.org/detail.go?type=gene&acc=4363

BIMP082138

ABCC1

Homo sapiens (human)

Apigenin inhibits the reaction [ABCC1 protein results in increased uptake of leukotriene C4]|ABCC1 protein results in increased uptake of leukotriene c4|glutathione promotes the reaction [genistein affects the reaction [ABCC1 protein results in increased uptake of leukotriene c4]]|kaempferol inhibits the reaction [ABCC1 protein results in increased uptake of leukotriene c4]|quercetin inhibits the reaction [ABCC1 protein results in increased uptake of leukotriene c4]|naringenin affects the reaction [ABCC1 protein results in increased uptake of leukotriene c4]|glutathione promotes the reaction [apigenin inhibits the reaction [ABCC1 protein results in increased uptake of leukotriene c4]]|genistein affects the reaction [ABCC1 protein results in increased uptake of leukotriene c4]|glutathione promotes the reaction [naringenin affects the reaction [ABCC1 protein results in increased uptake of leukotriene c4]]|myricetin inhibits the reaction [ABCC1 protein results in increased uptake of leukotriene C4]

https://ctdbase.org/detail.go?type=gene&acc=4363

BIMP082138

ABCC1

Homo sapiens (human)

Adenosine triphosphate promotes the reaction [ABCC1 protein affects the transport of leukotriene C4]

https://ctdbase.org/detail.go?type=gene&acc=4363

BIMP082138

ABCC1

Homo sapiens (human)

Bilirubin inhibits the reaction [ABCC1 protein affects the transport of leukotriene C4]

https://ctdbase.org/detail.go?type=gene&acc=4363

BIMP082138

ABCC1

Homo sapiens (human)

Glutathione disulfide promotes the reaction [leukotriene C4 analog binds to ABCC1 protein]|leukotriene C4 analog binds to ABCC1 protein

https://ctdbase.org/detail.go?type=gene&acc=4363

BIMP082138

ABCC1

Homo sapiens (human)

[nimustine results in increased expression of ABCC1 protein] which results in increased transport of leukotriene C4

https://ctdbase.org/detail.go?type=gene&acc=4363

BIMP082138

ABCC1

Macaca fascicularis (crab-eating macaque)

ABCC1 protein affects the transport of leukotriene C4

https://ctdbase.org/detail.go?type=gene&acc=4363

BIMP082138

ABCC1

Oryctolagus cuniculus (rabbit)

Probenecid inhibits the reaction [ABCC1 protein results in increased export of leukotriene C4]|[IL6 protein co-treated with TNF protein co-treated with IL1B protein] promotes the reaction [ABCC1 protein results in increased export of leukotriene C4]|[IL6 protein results in increased expression of ABCC1 protein] which results in increased export of leukotriene C4|ABCC1 protein results in increased export of leukotriene c4|sodium azide inhibits the reaction [ABCC1 protein results in increased export of leukotriene C4]|[TNF protein results in increased expression of ABCC1 protein] which results in increased export of leukotriene C4

https://ctdbase.org/detail.go?type=gene&acc=4363

BIMP082138

ABCC1

Homo sapiens (human)

ABCC1 protein binds to and results in increased transport of leukotriene C4|[4-phenylbutyric acid results in increased activity of ABCC1 protein mutant form] which results in increased transport of leukotriene C4

https://ctdbase.org/detail.go?type=gene&acc=4363

BIMP082138

ABCC1

Homo sapiens (human)

ABCC1 protein results in increased transport of leukotriene c4|indomethacin inhibits the reaction [ABCC1 protein results in increased transport of leukotriene C4]

https://ctdbase.org/detail.go?type=gene&acc=4363

BIMP082138

ABCC1

Homo sapiens (human)

[adenosine triphosphate binds to ABCC1 protein] inhibits the reaction [leukotriene C4 binds to ABCC1 protein]

https://ctdbase.org/detail.go?type=gene&acc=4363

BIMP081709

ABCC1

Homo sapiens (human)

Silymarin inhibits the reaction [ABCC1 protein results in increased export of S-(2,4-dinitrophenyl)glutathione]|silymarin inhibits the reaction [ABCC1 protein results in increased export of fluorexon]|silymarin inhibits the reaction [ABCC1 protein results in increased hydrolysis of adenosine triphosphate]|silymarin inhibits the reaction [ABCC1 protein results in decreased susceptibility to etoposide]

https://ctdbase.org/detail.go?type=gene&acc=4363

BIMP080548

ABCC1

Homo sapiens (human)

https://www.dgidb.org/genes/hgnc:51

BIMP080548

ABCC1

Homo sapiens (human)

Probenecid affects the activity of ABCC1 protein

https://ctdbase.org/detail.go?type=gene&acc=4363

BIMP080548

ABCC1

Homo sapiens (human)

Probenecid affects the reaction [ABCC1 protein results in increased transport of valproic acid]

https://ctdbase.org/detail.go?type=gene&acc=4363

BIMP080548

ABCC1

Homo sapiens (human)

Probenecid inhibits the reaction [ABCC1 protein results in increased export of 2',7'-bis-(carboxypropyl)-5(6)-carboxyfluorescein]

https://ctdbase.org/detail.go?type=gene&acc=4363