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SCFBio, IIT Delhi Hauz Khas, New Delhi

Molecular Targets

Interactions between compounds and specific gene/protein targets.

Total Rows 750,454
Pages 30,019
BIMP_ID Target Name Gene Organism Action Source URL
ABCC1
Homo sapiens (human)
Genistein promotes the reaction [ABCC1 protein results in increased uptake of glutathione]|verapamil promotes the reaction [ABCC1 protein results in increased uptake of glutathione]|naringenin promotes the reaction [ABCC1 protein results in increased uptake of glutathione]|apigenin promotes the reaction [ABCC1 protein results in increased uptake of glutathione]|quercetin promotes the reaction [ABCC1 protein results in increased uptake of glutathione]|abcc1 protein results in increased uptake of glutathione
https://ctdbase.org/detail.go?type=gene&acc=4363
ABCC1
Homo sapiens (human)
[buthionine sulfoximine results in decreased abundance of glutathione] inhibits the reaction [ABCC1 results in decreased susceptibility to arsenite]|glutathione promotes the reaction [ABCC1 results in increased transport of methylarsine analog]|[buthionine sulfoximine results in decreased abundance of glutathione] inhibits the reaction [ABCC1 results in decreased susceptibility to monomethylarsonous acid analog]|vincristine inhibits the reaction [glutathione promotes the reaction [ABCC1 results in increased transport of methylarsine analog]]|glutathione disulfide inhibits the reaction [glutathione promotes the reaction [ABCC1 results in increased transport of methylarsine analog]]|estradiol-17 beta-glucuronide inhibits the reaction [glutathione promotes the reaction [ABCC1 results in increased transport of methylarsine analog]]
https://ctdbase.org/detail.go?type=gene&acc=4363
ABCC1
Homo sapiens (human)
[glutathione binds to 10-nitro-oleic acid] promotes the reaction [ABCC1 protein results in increased export of 10-nitro-oleic acid metabolite]
https://ctdbase.org/detail.go?type=gene&acc=4363
ABCC1
Homo sapiens (human)
Glutathione binds to and affects the folding of and affects the activity of ABCC1 protein
https://ctdbase.org/detail.go?type=gene&acc=4363
ABCC1
Homo sapiens (human)
Glutathione promotes the reaction [genistein affects the reaction [ABCC1 protein results in increased uptake of leukotriene c4]]|glutathione promotes the reaction [apigenin inhibits the reaction [ABCC1 protein results in increased uptake of leukotriene c4]]|[glutathione co-treated with apigenin] affects the reaction [ABCC1 protein results in increased uptake of estradiol-17 beta-glucuronide]|[glutathione co-treated with naringenin] inhibits the reaction [ABCC1 protein results in increased uptake of estradiol-17 beta-glucuronide]|glutathione promotes the reaction [naringenin results in increased activity of ABCC1 protein]|glutathione promotes the reaction [naringenin affects the reaction [ABCC1 protein results in increased uptake of leukotriene C4]]
https://ctdbase.org/detail.go?type=gene&acc=4363
ABCC1
Homo sapiens (human)
Glutathione inhibits the reaction [titanium dioxide results in increased expression of ABCC1 mrna]
https://ctdbase.org/detail.go?type=gene&acc=4363
ABCC1
Homo sapiens (human)
Glutathione promotes the reaction [ABCC1 protein affects the export of 4-nitroquinoline-1-oxide analog]
https://ctdbase.org/detail.go?type=gene&acc=4363
ABCC1
Homo sapiens (human)
Glutathione promotes the reaction [ABCC1 protein affects the transport of bilirubin]
https://ctdbase.org/detail.go?type=gene&acc=4363
ABCC1
Homo sapiens (human)
Glutathione results in increased stability of and results in decreased degradation of and affects the localization of ABCC1 protein mutant form
https://ctdbase.org/detail.go?type=gene&acc=4363
ABCC1
Mus musculus (house mouse)
ABCC1 protein affects the export of glutathione
https://ctdbase.org/detail.go?type=gene&acc=4363
ABCC1
Mus musculus (house mouse)
ABCC1 protein affects the reaction [AGT protein results in decreased abundance of glutathione]
https://ctdbase.org/detail.go?type=gene&acc=4363
ABCC1
Mus musculus (house mouse)
ABCC1 protein promotes the reaction [nitric oxide results in increased secretion of glutathione]
https://ctdbase.org/detail.go?type=gene&acc=4363
ABCC1
Rattus norvegicus (Norway rat)
[verlukast results in decreased activity of ABCC1 protein] inhibits the reaction [arsenates results in increased export of glutathione]
https://ctdbase.org/detail.go?type=gene&acc=4363
ABCC1
Homo sapiens (human)
ABCC1 protein affects the export of glutathione
https://ctdbase.org/detail.go?type=gene&acc=4363
ABCC1
Homo sapiens (human)
ABCC1 protein promotes the reaction [verapamil results in decreased abundance of glutathione]|abcc1 protein promotes the reaction [5-oxo-hexahydroquinoline analog results in decreased abundance of glutathione]
https://ctdbase.org/detail.go?type=gene&acc=4363
ABCC1
Homo sapiens (human)
ABCC1 protein results in increased export of glutathione
https://ctdbase.org/detail.go?type=gene&acc=4363
ABCC1
Homo sapiens (human)
https://www.dgidb.org/genes/hgnc:51
ABCC1
Homo sapiens (human)
ABCC1 protein affects the susceptibility to vinblastine
https://ctdbase.org/detail.go?type=gene&acc=4363
ABCC1
Homo sapiens (human)
ABCC1 protein results in decreased susceptibility to vinblastine
https://ctdbase.org/detail.go?type=gene&acc=4363
ABCC1
Rattus norvegicus (Norway rat)
ABCC1 protein results in decreased susceptibility to vinblastine
https://ctdbase.org/detail.go?type=gene&acc=4363
ABCC1
Homo sapiens (human)
Glutathione affects the reaction [ABCC1 protein results in increased secretion of arsenic trioxide]|glutathione affects the reaction [ABCC1 protein results in increased secretion of antimony potassium tartrate]
https://ctdbase.org/detail.go?type=gene&acc=4363
ABCC1
Homo sapiens (human)
[matairesinol affects the activity of ABCC1 protein] which results in increased abundance of fluorexon
https://ctdbase.org/detail.go?type=gene&acc=4363
ABCC1
Homo sapiens (human)
Deoxycholic acid inhibits the reaction [ABCC1 protein results in increased export of 2',7'-bis-(carboxypropyl)-5(6)-carboxyfluorescein]
https://ctdbase.org/detail.go?type=gene&acc=4363
ABCC1
Homo sapiens (human)
[glycochenodeoxycholic acid co-treated with deoxycholic acid co-treated with chenodeoxycholic acid co-treated with glycodeoxycholic acid co-treated with glycocholic acid co-treated with tartrazine] results in increased expression of ABCC1 mrna|[glycochenodeoxycholic acid co-treated with deoxycholic acid co-treated with chenodeoxycholic acid co-treated with glycodeoxycholic acid co-treated with glycocholic acid co-treated with acetaminophen] results in increased expression of ABCC1 mRNA
https://ctdbase.org/detail.go?type=gene&acc=4363
ABCC1
Homo sapiens (human)
Cholic acid inhibits the reaction [ABCC1 protein results in increased export of 2',7'-bis-(carboxypropyl)-5(6)-carboxyfluorescein]
https://ctdbase.org/detail.go?type=gene&acc=4363
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