SCFBio, IIT Delhi
Hauz Khas, New Delhi
BIMP
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SCFBio, IIT Delhi
Interactions between compounds and specific gene/protein targets.
| BIMP_ID | Target Name | Gene | Organism | Action | Source URL |
|---|---|---|---|---|---|
|
ABCC1
|
Homo sapiens (human)
|
ABCC1 results in decreased susceptibility to vincristine
|
https://ctdbase.org/detail.go?type=gene&acc=4363
|
||
|
ABCC1
|
Homo sapiens (human)
|
Buthionine sulfoximine inhibits the reaction [ABCC1 protein results in decreased susceptibility to vincristine]|zafirlukast inhibits the reaction [ABCC1 protein results in decreased susceptibility to vincristine]|verlukast inhibits the reaction [ABCC1 protein results in decreased susceptibility to vincristine]
|
https://ctdbase.org/detail.go?type=gene&acc=4363
|
||
|
ABCC1
|
Homo sapiens (human)
|
Cyclosporine inhibits the reaction [ABCC1 protein results in decreased susceptibility to vincristine]|verapamil inhibits the reaction [ABCC1 protein results in decreased susceptibility to vincristine]
|
https://ctdbase.org/detail.go?type=gene&acc=4363
|
||
|
ABCC1
|
Homo sapiens (human)
|
Vincristine inhibits the reaction [ABCC1 protein affects the transport of fluorexon]|doxorubicin inhibits the reaction [ABCC1 protein affects the transport of vincristine]
|
https://ctdbase.org/detail.go?type=gene&acc=4363
|
||
|
ABCC1
|
Homo sapiens (human)
|
GSTP1 protein promotes the reaction [ABCC1 protein results in decreased susceptibility to vincristine]
|
https://ctdbase.org/detail.go?type=gene&acc=4363
|
||
|
ABCC1
|
Homo sapiens (human)
|
[MYCN protein affects the expression of ABCC1 mrna] which affects the susceptibility to vincristine
|
https://ctdbase.org/detail.go?type=gene&acc=4363
|
||
|
ABCC1
|
Homo sapiens (human)
|
Quercetin promotes the reaction [ABCC1 protein results in decreased susceptibility to vincristine]
|
https://ctdbase.org/detail.go?type=gene&acc=4363
|
||
|
ABCC1
|
Homo sapiens (human)
|
Vincristine inhibits the reaction [glutathione promotes the reaction [ABCC1 results in increased transport of methylarsine analog]]
|
https://ctdbase.org/detail.go?type=gene&acc=4363
|
||
|
ABCC1
|
Homo sapiens (human)
|
[vincristine results in decreased susceptibility to vincristine] which results in increased expression of ABCC1 mRNA
|
https://ctdbase.org/detail.go?type=gene&acc=4363
|
||
|
ABCC1
|
Macaca fascicularis (crab-eating macaque)
|
ABCC1 protein results in decreased susceptibility to vincristine
|
https://ctdbase.org/detail.go?type=gene&acc=4363
|
||
|
ABCC1
|
Mus musculus (house mouse)
|
ABCC1 protein results in decreased susceptibility to vincristine
|
https://ctdbase.org/detail.go?type=gene&acc=4363
|
||
|
ABCC1
|
Mus musculus (house mouse)
|
ABCC1 results in decreased susceptibility to vincristine
|
https://ctdbase.org/detail.go?type=gene&acc=4363
|
||
|
ABCC1
|
Oryctolagus cuniculus (rabbit)
|
Indomethacin inhibits the reaction [ABCC1 protein results in increased export of vincristine]|cyclosporine inhibits the reaction [ABCC1 protein results in increased export of vincristine]|abcc1 protein results in increased export of vincristine|probenecid inhibits the reaction [ABCC1 protein results in increased export of vincristine]
|
https://ctdbase.org/detail.go?type=gene&acc=4363
|
||
|
ABCC1
|
Rattus norvegicus (Norway rat)
|
[verlukast results in decreased activity of ABCC1 protein] which results in increased uptake of vincristine|[probenecid results in decreased activity of ABCC1 protein] which results in increased uptake of vincristine|[sulfinpyrazone results in decreased activity of ABCC1 protein] which results in increased uptake of vincristine|[indomethacin results in decreased activity of ABCC1 protein] which results in increased uptake of vincristine|[genistein results in decreased activity of ABCC1 protein] which results in increased uptake of vincristine
|
https://ctdbase.org/detail.go?type=gene&acc=4363
|
||
|
ABCC1
|
Rattus norvegicus (Norway rat)
|
Vincristine results in increased expression of ABCC1 mRNA
|
https://ctdbase.org/detail.go?type=gene&acc=4363
|
||
|
ABCC1
|
Homo sapiens (human)
|
|
https://www.dgidb.org/genes/hgnc:51
|
||
|
ABCC1
|
Homo sapiens (human)
|
ABCC1 protein affects the transport of [arsenite co-treated with glutathione]
|
https://ctdbase.org/detail.go?type=gene&acc=4363
|
||
|
ABCC1
|
Homo sapiens (human)
|
ABCC1 protein results in decreased susceptibility to arsenite
|
https://ctdbase.org/detail.go?type=gene&acc=4363
|
||
|
ABCC1
|
Homo sapiens (human)
|
Monomethylarsonous acid analog inhibits the reaction [ABCC1 protein results in increased transport of arsenite analog]|abcc1 protein results in increased transport of arsenite analog
|
https://ctdbase.org/detail.go?type=gene&acc=4363
|
||
|
ABCC1
|
Homo sapiens (human)
|
ABCC1 results in increased transport of arsenite|buthionine sulfoximine inhibits the reaction [ABCC1 results in decreased susceptibility to arsenite]|[buthionine sulfoximine results in decreased abundance of glutathione] inhibits the reaction [ABCC1 results in decreased susceptibility to arsenite]|abcc1 results in decreased susceptibility to arsenite
|
https://ctdbase.org/detail.go?type=gene&acc=4363
|
||
|
ABCC1
|
Mus musculus (house mouse)
|
Arsenite results in decreased expression of ABCC1 protein
|
https://ctdbase.org/detail.go?type=gene&acc=4363
|
||
|
ABCC1
|
Mus musculus (house mouse)
|
Sulforaphane results in increased expression of ABCC1 mrna|nfe2l2 gene mutant form inhibits the reaction [sulforaphane results in increased expression of and results in increased activity of ABCC1 protein]|nfe2l2 gene mutant form inhibits the reaction [sulforaphane results in increased expression of ABCC1 mrna]|sulforaphane results in increased expression of and results in increased activity of ABCC1 protein
|
https://ctdbase.org/detail.go?type=gene&acc=4363
|
||
|
ABCC1
|
Moina macrocopa
|
Methoprene results in increased expression of ABCC1 mRNA
|
https://ctdbase.org/detail.go?type=gene&acc=4363
|
||
|
ABCC1
|
Homo sapiens (human)
|
Bisdemethoxycurcumin results in decreased activity of ABCC1 protein
|
https://ctdbase.org/detail.go?type=gene&acc=4363
|
||
|
ABCC1
|
Homo sapiens (human)
|
Curcumin III results in decreased activity of ABCC1 protein
|
https://ctdbase.org/detail.go?type=gene&acc=4363
|
No matching records found on this page.