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Interactions between compounds and specific gene/protein targets.
| BIMP_ID | Target Name | Gene | Organism | Action | Source URL |
|---|---|---|---|---|---|
|
ABCC1
|
Homo sapiens (human)
|
3',4',7-trihydroxyisoflavone inhibits the reaction [epirubicin results in increased expression of ABCC1 mrna]|3',4',7-trihydroxyisoflavone results in decreased expression of ABCC1 mrna|acetylcysteine inhibits the reaction [3',4',7-trihydroxyisoflavone results in decreased expression of ABCC1 mrna]|ascorbic acid inhibits the reaction [3',4',7-trihydroxyisoflavone results in decreased expression of ABCC1 mrna]|cat protein inhibits the reaction [3',4',7-trihydroxyisoflavone results in decreased expression of ABCC1 mrna]
|
https://ctdbase.org/detail.go?type=gene&acc=4363
|
||
|
ABCC1
|
Homo sapiens (human)
|
|
https://www.dgidb.org/genes/hgnc:51
|
||
|
ABCC1
|
Homo sapiens (human)
|
Genistein affects the activity of ABCC1 protein
|
https://ctdbase.org/detail.go?type=gene&acc=4363
|
||
|
ABCC1
|
Homo sapiens (human)
|
Glutathione promotes the reaction [genistein affects the reaction [ABCC1 protein results in increased uptake of leukotriene c4]]|genistein affects the reaction [ABCC1 protein results in increased uptake of leukotriene C4]
|
https://ctdbase.org/detail.go?type=gene&acc=4363
|
||
|
ABCC1
|
Homo sapiens (human)
|
Genistein analog results in decreased activity of ABCC1 protein
|
https://ctdbase.org/detail.go?type=gene&acc=4363
|
||
|
ABCC1
|
Homo sapiens (human)
|
Genistein promotes the reaction [ABCC1 protein results in increased uptake of glutathione]
|
https://ctdbase.org/detail.go?type=gene&acc=4363
|
||
|
ABCC1
|
Homo sapiens (human)
|
Genistein results in decreased activity of ABCC1 protein
|
https://ctdbase.org/detail.go?type=gene&acc=4363
|
||
|
ABCC1
|
Rattus norvegicus (Norway rat)
|
Genistein results in decreased activity of ABCC1 protein|[genistein results in decreased activity of ABCC1 protein] which results in increased uptake of vincristine
|
https://ctdbase.org/detail.go?type=gene&acc=4363
|
||
|
ABCC1
|
Homo sapiens (human)
|
Epsilon-viniferin inhibits the reaction [ABCC1 protein results in increased transport of 2',7'-bis-(carboxypropyl)-5(6)-carboxyfluorescein]|epsilon-viniferin results in decreased activity of ABCC1 protein
|
https://ctdbase.org/detail.go?type=gene&acc=4363
|
||
|
ABCC1
|
Homo sapiens (human)
|
Cycloartenyl ferulate inhibits the reaction [paraquat results in decreased expression of ABCC1 protein]|abcc1 protein promotes the reaction [cycloartenyl ferulate results in increased transport of and results in decreased abundance of paraquat]
|
https://ctdbase.org/detail.go?type=gene&acc=4363
|
||
|
ABCC1
|
Mus musculus (house mouse)
|
Tocotrienol, delta results in increased expression of ABCC1 mrna|tocotrienol, delta inhibits the reaction [lipopolysaccharides results in increased expression of ABCC1 mrna]
|
https://ctdbase.org/detail.go?type=gene&acc=4363
|
||
|
ABCC1
|
Homo sapiens (human)
|
Caffeic acid phenethyl ester metabolite results in decreased activity of ABCC1 protein
|
https://ctdbase.org/detail.go?type=gene&acc=4363
|
||
|
ABCC1
|
Homo sapiens (human)
|
3-methylquercetin results in decreased activity of ABCC1 protein
|
https://ctdbase.org/detail.go?type=gene&acc=4363
|
||
|
ABCC1
|
Homo sapiens (human)
|
Morin results in decreased activity of ABCC1 protein
|
https://ctdbase.org/detail.go?type=gene&acc=4363
|
||
|
ABCC1
|
Homo sapiens (human)
|
Daidzein promotes the reaction [ABCC1 protein results in increased hydrolysis of adenosine triphosphate]
|
https://ctdbase.org/detail.go?type=gene&acc=4363
|
||
|
ABCC1
|
Homo sapiens (human)
|
Myricetin inhibits the reaction [ABCC1 protein affects the export of and results in decreased susceptibility to vincristine]|myricetin inhibits the reaction [ABCC1 protein affects the export of vincristine]|myricetin inhibits the reaction [ABCC1 protein results in decreased susceptibility to vincristine]
|
https://ctdbase.org/detail.go?type=gene&acc=4363
|
||
|
ABCC1
|
Homo sapiens (human)
|
Myricetin inhibits the reaction [ABCC1 protein results in increased uptake of leukotriene C4]
|
https://ctdbase.org/detail.go?type=gene&acc=4363
|
||
|
ABCC1
|
Homo sapiens (human)
|
Myricetin results in decreased activity of ABCC1 protein
|
https://ctdbase.org/detail.go?type=gene&acc=4363
|
||
|
ABCC1
|
Homo sapiens (human)
|
Robinetin results in decreased activity of ABCC1 protein|robinetin inhibits the reaction [ABCC1 protein affects the export of fluorexon]
|
https://ctdbase.org/detail.go?type=gene&acc=4363
|
||
|
ABCC1
|
Homo sapiens (human)
|
Robinin affects the activity of ABCC1 protein
|
https://ctdbase.org/detail.go?type=gene&acc=4363
|
||
|
ABCC1
|
Homo sapiens (human)
|
Afromosin affects the activity of ABCC1 protein
|
https://ctdbase.org/detail.go?type=gene&acc=4363
|
||
|
ABCC1
|
Homo sapiens (human)
|
Verlukast inhibits the reaction [ABCC1 protein results in increased transport of zearalenone]|zearalenone inhibits the reaction [ABCC1 protein results in increased transport of calcein AM]|ABCC1 protein results in increased transport of zearalenone
|
https://ctdbase.org/detail.go?type=gene&acc=4363
|
||
|
ABCC1
|
Homo sapiens (human)
|
Zearalenone results in increased expression of ABCC1 protein
|
https://ctdbase.org/detail.go?type=gene&acc=4363
|
||
|
ABCC1
|
Rattus norvegicus (Norway rat)
|
Zearalenone affects the expression of ABCC1 mrna|zearalenone affects the expression of ABCC1 protein
|
https://ctdbase.org/detail.go?type=gene&acc=4363
|
||
|
ABCC1
|
Rattus norvegicus (Norway rat)
|
Zearalenone results in decreased expression of ABCC1 mrna|zearalenone results in decreased expression of ABCC1 protein
|
https://ctdbase.org/detail.go?type=gene&acc=4363
|
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