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SCFBio, IIT Delhi Hauz Khas, New Delhi

Molecular Targets

Interactions between compounds and specific gene/protein targets.

Total Rows 750,454
Pages 30,019
BIMP_ID Target Name Gene Organism Action Source URL
ABCC1
Mus musculus (house mouse)
Ethinyl estradiol affects the expression of ABCC1 mRNA
https://ctdbase.org/detail.go?type=gene&acc=4363
ABCC1
Mus musculus (house mouse)
Ethinyl estradiol results in increased expression of ABCC1 mrna|[tetrachlorodibenzodioxin co-treated with ethinyl estradiol] results in increased expression of ABCC1 mRNA
https://ctdbase.org/detail.go?type=gene&acc=4363
ABCC1
Danio rerio (zebrafish)
Dinitrochlorobenzene inhibits the reaction [arsenic results in decreased expression of ABCC1 mrna]
https://ctdbase.org/detail.go?type=gene&acc=4363
ABCC1
Homo sapiens (human)
Adenosine diphosphate binds to ABCC1 protein|vanadates promotes the reaction [adenosine diphosphate binds to ABCC1 protein]|adenosine diphosphate binds to ABCC1 protein mutant form|estradiol-17 beta-glucuronide inhibits the reaction [adenosine diphosphate binds to ABCC1 protein mutant form]|estradiol-17 beta-glucuronide inhibits the reaction [adenosine diphosphate binds to ABCC1 protein]
https://ctdbase.org/detail.go?type=gene&acc=4363
ABCC1
Homo sapiens (human)
ABCC1 protein results in decreased susceptibility to irinotecan
https://ctdbase.org/detail.go?type=gene&acc=4363
ABCC1
Homo sapiens (human)
Irinotecan analog results in decreased expression of ABCC1 mRNA
https://ctdbase.org/detail.go?type=gene&acc=4363
ABCC1
Homo sapiens (human)
[selenomethylselenocysteine co-treated with irinotecan] results in decreased expression of ABCC1
https://ctdbase.org/detail.go?type=gene&acc=4363
ABCC1
Homo sapiens (human)
ABCC1 gene SNP affects the susceptibility to zileuton
https://ctdbase.org/detail.go?type=gene&acc=4363
ABCC1
Homo sapiens (human)
https://www.dgidb.org/genes/hgnc:51
ABCC1
Homo sapiens (human)
[testosterone co-treated with calcitriol] results in increased expression of ABCC1 mrna|testosterone results in increased expression of ABCC1 mRNA
https://ctdbase.org/detail.go?type=gene&acc=4363
ABCC1
Mus musculus (house mouse)
[[ABCC1 gene mutant form results in increased susceptibility to testosterone deficiency] which results in decreased hydroxylation of testosterone] which results in decreased chemical synthesis of 6 beta-hydroxytestosterone|[[abcc1 gene mutant form results in increased susceptibility to testosterone deficiency] which results in decreased hydroxylation of testosterone] which results in decreased chemical synthesis of 15-hydroxytestosterone|[abcc1 gene mutant form results in increased hydroxylation of testosterone] which results in increased chemical synthesis of 16-hydroxytestosterone|[abcc1 gene mutant form results in increased susceptibility to testosterone deficiency] which results in increased expression of ABCC2 mrna|abcc1 gene mutant form inhibits the reaction [testosterone deficiency results in increased expression of ABCC4 mrna]|[abcc1 gene mutant form results in increased susceptibility to testosterone deficiency] which results in increased expression of SULT1B1 mrna|abcc1 gene mutant form results in increased hydroxylation of testosterone|abcc1 gene mutant form results in increased susceptibility to testosterone deficiency|testosterone deficiency inhibits the reaction [ABCC1 gene mutant form results in decreased expression of NFE2L2 mrna]|[abcc1 gene mutant form results in increased susceptibility to testosterone deficiency] which results in decreased expression of UGT2B5 mrna|[abcc1 gene mutant form results in increased susceptibility to testosterone deficiency] which results in decreased hydroxylation of testosterone|abcc1 gene mutant form inhibits the reaction [testosterone deficiency results in increased expression of ABCC2 mrna]
https://ctdbase.org/detail.go?type=gene&acc=4363
ABCC1
Mus musculus (house mouse)
ABCC1 protein affects the glucuronidation of testosterone
https://ctdbase.org/detail.go?type=gene&acc=4363
ABCC1
Homo sapiens (human)
Cyclosporine inhibits the reaction [ABCC1 protein affects the export of 5-carboxyfluorescein diacetate]
https://ctdbase.org/detail.go?type=gene&acc=4363
ABCC1
Homo sapiens (human)
Cyclosporine inhibits the reaction [ABCC1 protein results in decreased susceptibility to vincristine]
https://ctdbase.org/detail.go?type=gene&acc=4363
ABCC1
Homo sapiens (human)
Cyclosporine results in increased expression of ABCC1 mRNA
https://ctdbase.org/detail.go?type=gene&acc=4363
ABCC1
Oryctolagus cuniculus (rabbit)
Cyclosporine inhibits the reaction [ABCC1 protein results in increased export of vincristine]
https://ctdbase.org/detail.go?type=gene&acc=4363
ABCC1
Homo sapiens (human)
https://www.dgidb.org/genes/hgnc:51
ABCC1
Bos taurus (cattle)
ABCC1 protein results in decreased susceptibility to vincristine
https://ctdbase.org/detail.go?type=gene&acc=4363
ABCC1
Canis lupus familiaris (dog)
ABCC1 protein results in decreased susceptibility to vincristine
https://ctdbase.org/detail.go?type=gene&acc=4363
ABCC1
Homo sapiens (human)
ABCC1 gene SNP results in increased susceptibility to vincristine
https://ctdbase.org/detail.go?type=gene&acc=4363
ABCC1
Homo sapiens (human)
Myricetin inhibits the reaction [ABCC1 protein affects the export of and results in decreased susceptibility to vincristine]|abcc1 protein affects the export of and results in decreased susceptibility to vincristine|myricetin inhibits the reaction [ABCC1 protein affects the export of vincristine]|myricetin inhibits the reaction [ABCC1 protein results in decreased susceptibility to vincristine]|abcc1 protein affects the export of vincristine
https://ctdbase.org/detail.go?type=gene&acc=4363
ABCC1
Homo sapiens (human)
ABCC1 protein affects the susceptibility to vincristine
https://ctdbase.org/detail.go?type=gene&acc=4363
ABCC1
Homo sapiens (human)
ABCC1 protein affects the transport of vincristine
https://ctdbase.org/detail.go?type=gene&acc=4363
ABCC1
Homo sapiens (human)
ABCC1 protein mutant form affects the transport of vincristine
https://ctdbase.org/detail.go?type=gene&acc=4363
ABCC1
Homo sapiens (human)
ABCC1 protein results in decreased susceptibility to vincristine
https://ctdbase.org/detail.go?type=gene&acc=4363
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