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Interactions between compounds and specific gene/protein targets.
| BIMP_ID | Target Name | Gene | Organism | Action | Source URL |
|---|---|---|---|---|---|
|
Abcb1b
|
Rattus norvegicus (Norway rat)
|
Indole-3-carbinol affects the expression of ABCB1B mRNA
|
https://ctdbase.org/detail.go?type=gene&acc=18669
|
||
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Abcb1b
|
Rattus norvegicus (Norway rat)
|
[indole-3-carbinol co-treated with diethylnitrosamine] results in increased expression of ABCB1B mRNA
|
https://ctdbase.org/detail.go?type=gene&acc=18669
|
||
|
Abcb1b
|
Rattus norvegicus (Norway rat)
|
Ochratoxin A results in increased expression of ABCB1B mRNA
|
https://ctdbase.org/detail.go?type=gene&acc=18669
|
||
|
Abcb1b
|
Mus musculus (house mouse)
|
ABCB1B protein affects the susceptibility to quinidine
|
https://ctdbase.org/detail.go?type=gene&acc=18669
|
||
|
Abcb1b
|
Rattus norvegicus (Norway rat)
|
Quinidine affects the activity of ABCB1B protein
|
https://ctdbase.org/detail.go?type=gene&acc=18669
|
||
|
Abcb1b
|
Mus musculus (house mouse)
|
ABCB1B protein affects the susceptibility to loratadine
|
https://ctdbase.org/detail.go?type=gene&acc=18669
|
||
|
Abcb1b
|
Mus musculus (house mouse)
|
2-(4-morpholinyl)-8-phenyl-4H-1-benzopyran-4-one promotes the reaction [curcumin results in decreased expression of ABCB1B protein]|2-(4-morpholinyl)-8-phenyl-4H-1-benzopyran-4-one inhibits the reaction [[NFKB1 protein binds to RELA protein] which results in increased expression of ABCB1B mrna]|2-(4-morpholinyl)-8-phenyl-4H-1-benzopyran-4-one results in decreased expression of ABCB1B protein
|
https://ctdbase.org/detail.go?type=gene&acc=18669
|
||
|
Abcb1b
|
Rattus norvegicus (Norway rat)
|
Berberine results in increased expression of ABCB1B mRNA
|
https://ctdbase.org/detail.go?type=gene&acc=18669
|
||
|
Abcb1b
|
Mus musculus (house mouse)
|
ABCB1B protein affects the susceptibility to verapamil
|
https://ctdbase.org/detail.go?type=gene&acc=18669
|
||
|
Abcb1b
|
Rattus norvegicus (Norway rat)
|
Verapamil results in decreased activity of ABCB1B protein
|
https://ctdbase.org/detail.go?type=gene&acc=18669
|
||
|
Abcb1b
|
Mus musculus (house mouse)
|
Benzo(a)pyrene affects the expression of ABCB1B mRNA
|
https://ctdbase.org/detail.go?type=gene&acc=18669
|
||
|
Abcb1b
|
Mus musculus (house mouse)
|
Benzo(a)pyrene results in increased expression of ABCB1B mRNA
|
https://ctdbase.org/detail.go?type=gene&acc=18669
|
||
|
Abcb1b
|
Rattus norvegicus (Norway rat)
|
Benzo(a)pyrene promotes the reaction [TNF protein results in increased expression of ABCB1B mrna]|benzo(a)pyrene results in increased expression of ABCB1B mrna|tnf protein promotes the reaction [benzo(a)pyrene results in increased expression of ABCB1B mrna]
|
https://ctdbase.org/detail.go?type=gene&acc=18669
|
||
|
Abcb1b
|
Mus musculus (house mouse)
|
Resveratrol results in increased expression of ABCB1B protein
|
https://ctdbase.org/detail.go?type=gene&acc=18669
|
||
|
ABCB1LA
|
Gallus gallus (chicken)
|
Dexamethasone results in decreased expression of ABCB1LA mRNA
|
https://ctdbase.org/detail.go?type=gene&acc=420534
|
||
|
ABCB4
|
Rattus norvegicus (Norway rat)
|
Dexamethasone results in increased expression of ABCB4 mRNA
|
https://ctdbase.org/detail.go?type=gene&acc=5244
|
||
|
ABCB4
|
Homo sapiens (human)
|
|
https://www.dgidb.org/genes/hgnc:45
|
||
|
ABCB4
|
Homo sapiens (human)
|
Estradiol results in decreased expression of ABCB4 mRNA
|
https://ctdbase.org/detail.go?type=gene&acc=5244
|
||
|
ABCB4
|
Oryzias latipes (Japanese medaka)
|
Estradiol results in decreased expression of ABCB4 mRNA
|
https://ctdbase.org/detail.go?type=gene&acc=5244
|
||
|
ABCB4
|
Homo sapiens (human)
|
Cyclosporine results in decreased expression of ABCB4 mRNA
|
https://ctdbase.org/detail.go?type=gene&acc=5244
|
||
|
ABCB4
|
Homo sapiens (human)
|
Cyclosporine results in increased expression of ABCB4 mRNA
|
https://ctdbase.org/detail.go?type=gene&acc=5244
|
||
|
ABCB4
|
Homo sapiens (human)
|
[glycochenodeoxycholic acid co-treated with deoxycholic acid co-treated with chenodeoxycholic acid co-treated with glycodeoxycholic acid co-treated with glycocholic acid co-treated with cyclosporine] results in decreased expression of ABCB4 mRNA
|
https://ctdbase.org/detail.go?type=gene&acc=5244
|
||
|
ABCB4
|
Mus musculus (house mouse)
|
Cyclosporine results in decreased expression of ABCB4 mRNA
|
https://ctdbase.org/detail.go?type=gene&acc=5244
|
||
|
ABCB4
|
Homo sapiens (human)
|
Cyclosporine affects the localization of ABCB4 protein mutant form|cyclosporine affects the metabolism of and affects the folding of ABCB4 protein mutant form
|
https://ctdbase.org/detail.go?type=gene&acc=5244
|
||
|
ABCB4
|
Rattus norvegicus (Norway rat)
|
Oxycodone results in increased expression of ABCB4 mRNA
|
https://ctdbase.org/detail.go?type=gene&acc=5244
|
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