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SCFBio, IIT Delhi Hauz Khas, New Delhi

Molecular Targets

Interactions between compounds and specific gene/protein targets.

Total Rows 750,454
Pages 30,019
BIMP_ID Target Name Gene Organism Action Source URL
Abcb1b
Rattus norvegicus (Norway rat)
Indole-3-carbinol affects the expression of ABCB1B mRNA
https://ctdbase.org/detail.go?type=gene&acc=18669
Abcb1b
Rattus norvegicus (Norway rat)
[indole-3-carbinol co-treated with diethylnitrosamine] results in increased expression of ABCB1B mRNA
https://ctdbase.org/detail.go?type=gene&acc=18669
Abcb1b
Rattus norvegicus (Norway rat)
Ochratoxin A results in increased expression of ABCB1B mRNA
https://ctdbase.org/detail.go?type=gene&acc=18669
Abcb1b
Mus musculus (house mouse)
ABCB1B protein affects the susceptibility to quinidine
https://ctdbase.org/detail.go?type=gene&acc=18669
Abcb1b
Rattus norvegicus (Norway rat)
Quinidine affects the activity of ABCB1B protein
https://ctdbase.org/detail.go?type=gene&acc=18669
Abcb1b
Mus musculus (house mouse)
ABCB1B protein affects the susceptibility to loratadine
https://ctdbase.org/detail.go?type=gene&acc=18669
Abcb1b
Mus musculus (house mouse)
2-(4-morpholinyl)-8-phenyl-4H-1-benzopyran-4-one promotes the reaction [curcumin results in decreased expression of ABCB1B protein]|2-(4-morpholinyl)-8-phenyl-4H-1-benzopyran-4-one inhibits the reaction [[NFKB1 protein binds to RELA protein] which results in increased expression of ABCB1B mrna]|2-(4-morpholinyl)-8-phenyl-4H-1-benzopyran-4-one results in decreased expression of ABCB1B protein
https://ctdbase.org/detail.go?type=gene&acc=18669
Abcb1b
Rattus norvegicus (Norway rat)
Berberine results in increased expression of ABCB1B mRNA
https://ctdbase.org/detail.go?type=gene&acc=18669
Abcb1b
Mus musculus (house mouse)
ABCB1B protein affects the susceptibility to verapamil
https://ctdbase.org/detail.go?type=gene&acc=18669
Abcb1b
Rattus norvegicus (Norway rat)
Verapamil results in decreased activity of ABCB1B protein
https://ctdbase.org/detail.go?type=gene&acc=18669
Abcb1b
Mus musculus (house mouse)
Benzo(a)pyrene affects the expression of ABCB1B mRNA
https://ctdbase.org/detail.go?type=gene&acc=18669
Abcb1b
Mus musculus (house mouse)
Benzo(a)pyrene results in increased expression of ABCB1B mRNA
https://ctdbase.org/detail.go?type=gene&acc=18669
Abcb1b
Rattus norvegicus (Norway rat)
Benzo(a)pyrene promotes the reaction [TNF protein results in increased expression of ABCB1B mrna]|benzo(a)pyrene results in increased expression of ABCB1B mrna|tnf protein promotes the reaction [benzo(a)pyrene results in increased expression of ABCB1B mrna]
https://ctdbase.org/detail.go?type=gene&acc=18669
Abcb1b
Mus musculus (house mouse)
Resveratrol results in increased expression of ABCB1B protein
https://ctdbase.org/detail.go?type=gene&acc=18669
ABCB1LA
Gallus gallus (chicken)
Dexamethasone results in decreased expression of ABCB1LA mRNA
https://ctdbase.org/detail.go?type=gene&acc=420534
ABCB4
Rattus norvegicus (Norway rat)
Dexamethasone results in increased expression of ABCB4 mRNA
https://ctdbase.org/detail.go?type=gene&acc=5244
ABCB4
Homo sapiens (human)
https://www.dgidb.org/genes/hgnc:45
ABCB4
Homo sapiens (human)
Estradiol results in decreased expression of ABCB4 mRNA
https://ctdbase.org/detail.go?type=gene&acc=5244
ABCB4
Oryzias latipes (Japanese medaka)
Estradiol results in decreased expression of ABCB4 mRNA
https://ctdbase.org/detail.go?type=gene&acc=5244
ABCB4
Homo sapiens (human)
Cyclosporine results in decreased expression of ABCB4 mRNA
https://ctdbase.org/detail.go?type=gene&acc=5244
ABCB4
Homo sapiens (human)
Cyclosporine results in increased expression of ABCB4 mRNA
https://ctdbase.org/detail.go?type=gene&acc=5244
ABCB4
Homo sapiens (human)
[glycochenodeoxycholic acid co-treated with deoxycholic acid co-treated with chenodeoxycholic acid co-treated with glycodeoxycholic acid co-treated with glycocholic acid co-treated with cyclosporine] results in decreased expression of ABCB4 mRNA
https://ctdbase.org/detail.go?type=gene&acc=5244
ABCB4
Mus musculus (house mouse)
Cyclosporine results in decreased expression of ABCB4 mRNA
https://ctdbase.org/detail.go?type=gene&acc=5244
ABCB4
Homo sapiens (human)
Cyclosporine affects the localization of ABCB4 protein mutant form|cyclosporine affects the metabolism of and affects the folding of ABCB4 protein mutant form
https://ctdbase.org/detail.go?type=gene&acc=5244
ABCB4
Rattus norvegicus (Norway rat)
Oxycodone results in increased expression of ABCB4 mRNA
https://ctdbase.org/detail.go?type=gene&acc=5244
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