Interactions
Organism
Gene Name
| S.No | BIMP ID | Organism | Action | References |
|---|---|---|---|---|
| 1 | BIMP090429 | Mus musculus (house mouse) | Dexamethasone results in increased expression of ABCB4 mRNA | |
| 2 | BIMP089937 | Mus musculus (house mouse) | Pirinixic acid results in increased expression of ABCB4 mRNA | |
| 3 | BIMP089374 | Mus musculus (house mouse) | Triclosan results in increased expression of ABCB4 mRNA | |
| 4 | BIMP090444 | Mus musculus (house mouse) | - |
No ref
|
| 5 | BIMP090535 | Mus musculus (house mouse) | Estradiol results in decreased expression of ABCB4 mRNA | |
| 6 | BIMP090535 | Mus musculus (house mouse) | Estradiol results in decreased expression of ABCB4 mRNA | |
| 7 | BIMP091061 | Mus musculus (house mouse) | [benzo(a)pyrene co-treated with ethinyl estradiol] results in increased expression of ABCB4 mRNA | |
| 8 | BIMP091061 | Mus musculus (house mouse) | [ethinyl estradiol co-treated with cholic acids] affects the expression of ABCB4 mRNA | |
| 9 | BIMP091061 | Mus musculus (house mouse) | Ethinyl estradiol affects the expression of ABCB4 mRNA | |
| 10 | BIMP091061 | Mus musculus (house mouse) | Ethinyl estradiol results in decreased expression of ABCB4 mRNA | |
| 11 | BIMP091061 | Mus musculus (house mouse) | Ethinyl estradiol results in increased expression of ABCB4 mRNA | |
| 12 | BIMP090784 | Mus musculus (house mouse) | Estrone results in increased expression of ABCB4 mRNA | |
| 13 | BIMP091055 | Mus musculus (house mouse) | [lard co-treated with cholesterol, dietary co-treated with dietary sucrose co-treated with fructose co-treated with glucose co-treated with 2,4-dichlorophenoxyacetic acid] results in increased expression of ABCB4 mRNA | |
| 14 | BIMP090947 | Mus musculus (house mouse) | Cantharidin results in decreased expression of ABCB4 mRNA | |
| 15 | BIMP087829 | Mus musculus (house mouse) | [vincristine results in decreased susceptibility to vincristine] which affects the expression of ABCB4 mRNA | |
| 16 | BIMP087829 | Mus musculus (house mouse) | - |
No ref
|
| 17 | BIMP088120 | Mus musculus (house mouse) | Arsenite affects the expression of ABCB4 mRNA | |
| 18 | BIMP088644 | Mus musculus (house mouse) | Doxycycline results in decreased expression of ABCB4 mRNA | |
| 19 | BIMP088673 | Mus musculus (house mouse) | Tetracycline results in decreased expression of ABCB4 mRNA | |
| 20 | BIMP088673 | Mus musculus (house mouse) | Tetracycline results in decreased expression of ABCB4 mRNA | |
| 21 | BIMP084816 | Mus musculus (house mouse) | Licochalcone B results in increased expression of ABCB4 mRNA | |
| 22 | BIMP082880 | Mus musculus (house mouse) | Cyclosporine results in decreased expression of ABCB4 mRNA | |
| 23 | BIMP082880 | Mus musculus (house mouse) | Cyclosporine results in increased expression of ABCB4 mRNA | |
| 24 | BIMP082880 | Mus musculus (house mouse) | [glycochenodeoxycholic acid co-treated with deoxycholic acid co-treated with chenodeoxycholic acid co-treated with glycodeoxycholic acid co-treated with glycocholic acid co-treated with cyclosporine] results in decreased expression of ABCB4 mRNA | |
| 25 | BIMP082880 | Mus musculus (house mouse) | Cyclosporine results in decreased expression of ABCB4 mRNA | |
| 26 | BIMP082880 | Mus musculus (house mouse) | Cyclosporine affects the localization of ABCB4 protein mutant form|cyclosporine affects the metabolism of and affects the folding of ABCB4 protein mutant form | |
| 27 | BIMP082896 | Mus musculus (house mouse) | Oxycodone results in increased expression of ABCB4 mRNA | |
| 28 | BIMP082880 | Mus musculus (house mouse) | - |
No ref
|
| 29 | BIMP080430 | Mus musculus (house mouse) | Colforsin results in decreased expression of ABCB4 mrna|n-(2-(4-bromocinnamylamino)ethyl)-5-isoquinolinesulfonamide inhibits the reaction [colforsin results in decreased expression of ABCB4 mrna]|colforsin inhibits the reaction [doxorubicin results in increased expression of ABCB4 mrna] | |
| 30 | BIMP079116 | Mus musculus (house mouse) | Nortriptyline results in decreased activity of ABCB4 protein | |
| 31 | BIMP082224 | Mus musculus (house mouse) | Senecionine results in decreased expression of ABCB4 mRNA | |
| 32 | BIMP082095 | Mus musculus (house mouse) | Quercetin results in decreased expression of ABCB4 mRNA | |
| 33 | BIMP082126 | Mus musculus (house mouse) | Calcitriol promotes the reaction [ABCB4 protein affects the transport of adefovir] | |
| 34 | BIMP082231 | Mus musculus (house mouse) | Genistein results in decreased expression of ABCB4 mRNA | |
| 35 | BIMP082233 | Mus musculus (house mouse) | Clavulanic acid results in decreased expression of ABCB4 mRNA | |
| 36 | BIMP073529 | Mus musculus (house mouse) | Loratadine results in decreased activity of ABCB4 protein | |
| 37 | BIMP073251 | Mus musculus (house mouse) | Isoproterenol results in decreased expression of ABCB4 mRNA | |
| 38 | BIMP072841 | Mus musculus (house mouse) | Glyphosate results in increased expression of ABCB4 mRNA | |
| 39 | BIMP071726 | Mus musculus (house mouse) | Diclofenac results in decreased activity of ABCB4 protein | |
| 40 | BIMP071726 | Mus musculus (house mouse) | Diclofenac results in decreased expression of ABCB4 mRNA | |
| 41 | BIMP072198 | Mus musculus (house mouse) | [NOG protein co-treated with valproic acid co-treated with dorsomorphin co-treated with 4-(5-benzo(1,3)dioxol-5-yl-4-pyridin-2-yl-1H-imidazol-2-yl)benzamide] results in increased expression of ABCB4 mRNA | |
| 42 | BIMP072198 | Mus musculus (house mouse) | Valproic acid affects the expression of ABCB4 mRNA | |
| 43 | BIMP072198 | Mus musculus (house mouse) | Valproic acid results in decreased methylation of ABCB4 gene | |
| 44 | BIMP072198 | Mus musculus (house mouse) | Valproic acid results in increased expression of ABCB4 mRNA | |
| 45 | BIMP072198 | Mus musculus (house mouse) | Valproic acid results in increased expression of ABCB4 protein | |
| 46 | BIMP072198 | Mus musculus (house mouse) | Valproic acid results in increased expression of ABCB4 mRNA | |
| 47 | BIMP071247 | Mus musculus (house mouse) | Ciprofibrate results in increased expression of ABCB4 mrna|ciprofibrate results in increased expression of ABCB4 protein | |
| 48 | BIMP071152 | Mus musculus (house mouse) | [lard co-treated with cholesterol, dietary co-treated with dietary sucrose co-treated with fructose co-treated with glucose co-treated with 2,4-dichlorophenoxyacetic acid] results in increased expression of ABCB4 mRNA | |
| 49 | BIMP071185 | Mus musculus (house mouse) | Fumonisin B1 results in increased expression of ABCB4 mRNA | |
| 50 | BIMP071289 | Mus musculus (house mouse) | [clofibrate co-treated with acetaminophen] affects the expression of ABCB4 mrna|ppara affects the reaction [[clofibrate co-treated with acetaminophen] affects the expression of ABCB4 mrna] | |
| 51 | BIMP071289 | Mus musculus (house mouse) | Clofibrate results in increased expression of ABCB4 mRNA | |
| 52 | BIMP072777 | Mus musculus (house mouse) | Gentamicins results in decreased expression of ABCB4 mRNA | |
| 53 | BIMP072777 | Mus musculus (house mouse) | Gentamicins results in increased expression of ABCB4 mRNA | |
| 54 | BIMP072829 | Mus musculus (house mouse) | Glyburide results in increased expression of ABCB4 mRNA | |
| 55 | BIMP070286 | Mus musculus (house mouse) | [caffeine co-treated with coclaurine co-treated with aegeline co-treated with higenamine co-treated with yohimbine co-treated with hydrolyzable tannins] results in increased expression of ABCB4 mRNA | |
| 56 | BIMP068482 | Mus musculus (house mouse) | [benzo(a)pyrene co-treated with ethinyl estradiol] results in increased expression of ABCB4 mrna|benzo(a)pyrene results in increased expression of ABCB4 mRNA | |
| 57 | BIMP068482 | Mus musculus (house mouse) | Benzo(a)pyrene affects the methylation of ABCB4 intron | |
| 58 | BIMP068482 | Mus musculus (house mouse) | Benzo(a)pyrene results in decreased expression of ABCB4 mRNA | |
| 59 | BIMP068482 | Mus musculus (house mouse) | Benzo(a)pyrene results in increased expression of ABCB4 mRNA | |
| 60 | BIMP068482 | Mus musculus (house mouse) | Benzo(a)pyrene results in increased methylation of ABCB4 promoter|benzo(a)pyrene results in increased methylation of ABCB4 5' UTR | |
| 61 | BIMP070301 | Mus musculus (house mouse) | Verapamil results in decreased activity of ABCB4 protein | |
| 62 | BIMP070301 | Mus musculus (house mouse) | Verapamil results in decreased expression of ABCB4 mRNA | |
| 63 | BIMP070301 | Mus musculus (house mouse) | Verapamil results in decreased activity of ABCB4 protein | |
| 64 | BIMP070301 | Mus musculus (house mouse) | Verapamil inhibits the reaction [ABCB4 protein results in increased export of phosphatidylcholines] | |
| 65 | BIMP073605 | Mus musculus (house mouse) | Permethrin results in decreased expression of ABCB4 mRNA | |
| 66 | BIMP073605 | Mus musculus (house mouse) | [permethrin co-treated with DEET] results in increased methylation of ABCB4 gene | |
| 67 | BIMP073729 | Mus musculus (house mouse) | Methoxsalen results in decreased expression of ABCB4 mrna|methoxsalen results in decreased expression of ABCB4 protein | |
| 68 | BIMP072264 | Mus musculus (house mouse) | Ursodeoxycholic acid results in increased expression of ABCB4 mRNA | |
| 69 | BIMP072300 | Mus musculus (house mouse) | ABCB4 protein results in decreased susceptibility to doxorubicin | |
| 70 | BIMP072300 | Mus musculus (house mouse) | Colforsin inhibits the reaction [doxorubicin results in increased expression of ABCB4 mrna] | |
| 71 | BIMP072300 | Mus musculus (house mouse) | Doxorubicin results in increased expression of ABCB4 mRNA | |
| 72 | BIMP032227 | Mus musculus (house mouse) | [docetaxel results in decreased susceptibility to docetaxel] which results in increased expression of ABCB4 mRNA | |
| 73 | BIMP032379 | Mus musculus (house mouse) | 2,4-dichlorophenoxyacetic acid results in increased expression of ABCB4 mRNA | |
| 74 | BIMP032379 | Mus musculus (house mouse) | [lard co-treated with cholesterol, dietary co-treated with dietary sucrose co-treated with fructose co-treated with glucose co-treated with 2,4-dichlorophenoxyacetic acid] results in increased expression of ABCB4 mRNA | |
| 75 | BIMP028660 | Mus musculus (house mouse) | Alisol B 23-acetate promotes the reaction [1-naphthylisothiocyanate results in increased expression of ABCB4 mrna]|alisol B 23-acetate promotes the reaction [1-naphthylisothiocyanate results in increased expression of ABCB4 protein]|pregna-4,17-diene-3,16-dione inhibits the reaction [alisol B 23-acetate promotes the reaction [1-naphthylisothiocyanate results in increased expression of ABCB4 mrna]] | |
| 76 | BIMP026639 | Mus musculus (house mouse) | N-nitrosopyrrolidine results in decreased expression of ABCB4 mRNA | |
| 77 | BIMP036503 | Mus musculus (house mouse) | Schizandrin B inhibits the reaction [carbon tetrachloride results in decreased expression of ABCB4 mrna] | |
| 78 | BIMP064420 | Mus musculus (house mouse) | Aflatoxin B1 affects the expression of ABCB4 protein | |
| 79 | BIMP064420 | Mus musculus (house mouse) | [aflatoxin B1 co-treated with finrozole] results in increased expression of ABCB4 mRNA | |
| 80 | BIMP064420 | Mus musculus (house mouse) | Aflatoxin B1 results in decreased methylation of ABCB4 gene | |
| 81 | BIMP064718 | Mus musculus (house mouse) | Tacrine results in decreased activity of ABCB4 protein | |
| 82 | BIMP012975 | Mus musculus (house mouse) | 1,9-dideoxyforskolin results in decreased activity of ABCB4 protein | |
| 83 | BIMP014566 | Mus musculus (house mouse) | ABCB4 protein affects the export of sterols | |
| 84 | BIMP016529 | Mus musculus (house mouse) | [caffeine co-treated with coclaurine co-treated with aegeline co-treated with higenamine co-treated with yohimbine co-treated with hydrolyzable tannins] results in increased expression of ABCB4 mRNA | |
| 85 | BIMP067854 | Mus musculus (house mouse) | ABCB4 affects the secretion of cholic acid | |
| 86 | BIMP067854 | Mus musculus (house mouse) | Cholic acid results in increased expression of ABCB4 mRNA | |
| 87 | BIMP067854 | Mus musculus (house mouse) | Epiallopregnanolone sulfate inhibits the reaction [cholic acid results in increased expression of ABCB4 mrna] | |
| 88 | BIMP067942 | Mus musculus (house mouse) | [glycochenodeoxycholic acid co-treated with deoxycholic acid co-treated with chenodeoxycholic acid co-treated with glycodeoxycholic acid co-treated with glycocholic acid] results in increased expression of ABCB4 mrna|[glycochenodeoxycholic acid co-treated with deoxycholic acid co-treated with chenodeoxycholic acid co-treated with glycodeoxycholic acid co-treated with glycocholic acid co-treated with acetaminophen] results in decreased expression of ABCB4 mrna|[glycochenodeoxycholic acid co-treated with deoxycholic acid co-treated with chenodeoxycholic acid co-treated with glycodeoxycholic acid co-treated with glycocholic acid co-treated with cyclosporine] results in decreased expression of ABCB4 mrna|[glycochenodeoxycholic acid co-treated with deoxycholic acid co-treated with chenodeoxycholic acid co-treated with glycodeoxycholic acid co-treated with glycocholic acid co-treated with atazanavir sulfate] results in decreased expression of ABCB4 mrna|[glycochenodeoxycholic acid co-treated with deoxycholic acid co-treated with chenodeoxycholic acid co-treated with glycodeoxycholic acid co-treated with glycocholic acid co-treated with tartrazine] results in decreased expression of ABCB4 mrna|[glycochenodeoxycholic acid co-treated with deoxycholic acid co-treated with chenodeoxycholic acid co-treated with glycodeoxycholic acid co-treated with glycocholic acid co-treated with nefazodone] results in increased expression of ABCB4 mRNA | |
| 89 | BIMP067942 | Mus musculus (house mouse) | Deoxycholic acid affects the expression of ABCB4 mrna|slco1a1 protein affects the susceptibility to [deoxycholic acid affects the expression of ABCB4 mrna] | |
| 90 | BIMP067942 | Mus musculus (house mouse) | Deoxycholic acid results in increased expression of ABCB4 mRNA | |
| 91 | BIMP037961 | Mus musculus (house mouse) | [perfluorooctane sulfonic acid co-treated with cellulose] results in decreased expression of ABCB4 mRNA | |
| 92 | BIMP037097 | Mus musculus (house mouse) | Abrine results in decreased expression of ABCB4 mRNA | |
| 93 | BIMP037086 | Mus musculus (house mouse) | [caffeine co-treated with coclaurine co-treated with aegeline co-treated with higenamine co-treated with yohimbine co-treated with hydrolyzable tannins] results in increased expression of ABCB4 mRNA | |
| 94 | BIMP037221 | Mus musculus (house mouse) | Dronabinol affects the expression of ABCB4 mRNA | |
| 95 | BIMP019668 | Mus musculus (house mouse) | [bisphenol F co-treated with fulvestrant] results in increased methylation of ABCB4 gene | |
| 96 | BIMP022732 | Mus musculus (house mouse) | Tamsulosin results in decreased activity of ABCB4 protein | |
| 97 | BIMP025809 | Mus musculus (house mouse) | - |
No ref
|
| 98 | BIMP022067 | Mus musculus (house mouse) | ABCB4 protein affects the export of glutathione | |
| 99 | BIMP016724 | Mus musculus (house mouse) | [NOG protein co-treated with valproic acid co-treated with dorsomorphin co-treated with 4-(5-benzo(1,3)dioxol-5-yl-4-pyridin-2-yl-1H-imidazol-2-yl)benzamide] results in increased expression of ABCB4 mRNA | |
| 100 | BIMP094277 | Mus musculus (house mouse) | Bisphenol A results in decreased expression of ABCB4 mRNA | |
| 101 | BIMP094277 | Mus musculus (house mouse) | Bisphenol A results in increased expression of ABCB4 mRNA | |
| 102 | BIMP094277 | Mus musculus (house mouse) | Bisphenol A results in decreased expression of ABCB4 mRNA | |
| 103 | BIMP094277 | Mus musculus (house mouse) | Bisphenol A results in decreased expression of ABCB4 mRNA | |
| 104 | BIMP094277 | Mus musculus (house mouse) | Bisphenol A results in increased expression of ABCB4 mRNA | |
| 105 | BIMP091585 | Mus musculus (house mouse) | Cycloheximide inhibits the reaction [tetradecanoylphorbol acetate results in decreased expression of ABCB4 mrna] | |
| 106 | BIMP105476 | Mus musculus (house mouse) | Lithocholic acid results in increased expression of ABCB4 mRNA | |
| 107 | BIMP105101 | Mus musculus (house mouse) | Perfluorobutyric acid results in increased expression of ABCB4 mRNA | |
| 108 | BIMP103258 | Mus musculus (house mouse) | Benzo(e)pyrene results in decreased methylation of ABCB4 intron | |
| 109 | BIMP102866 | Mus musculus (house mouse) | [polyethyleneimine binds to gold] which results in decreased expression of ABCB4 mRNA | |
| 110 | BIMP101295 | Mus musculus (house mouse) | Diethylhexyl phthalate results in increased expression of ABCB4 mRNA | |
| 111 | BIMP101071 | Mus musculus (house mouse) | Furan results in increased expression of ABCB4 mRNA | |
| 112 | BIMP101994 | Mus musculus (house mouse) | Dimethyl phthalate results in decreased expression of ABCB4 mRNA | |
| 113 | BIMP095782 | Mus musculus (house mouse) | Methyleugenol results in decreased expression of ABCB4 mRNA | |
| 114 | BIMP100881 | Mus musculus (house mouse) | 1,3-butadiene results in decreased expression of ABCB4 mRNA | |
| 115 | BIMP093437 | Mus musculus (house mouse) | Cannabidiol results in decreased expression of ABCB4 mRNA | |
| 116 | BIMP093430 | Mus musculus (house mouse) | Pregna-4,17-diene-3,16-dione inhibits the reaction [alisol B 23-acetate promotes the reaction [1-naphthylisothiocyanate results in increased expression of ABCB4 mrna]] | |
| 117 | BIMP094240 | Mus musculus (house mouse) | Dichloroacetic acid results in increased expression of ABCB4 mRNA | |
| 118 | BIMP094661 | Mus musculus (house mouse) | 1,2-dithiol-3-thione results in decreased expression of ABCB4 mRNA | |
| 119 | BIMP095241 | Mus musculus (house mouse) | Ethanol results in increased expression of ABCB4 mRNA |