Molecular Targets : Dataset Browser

BIMP_ID	Target Name	Gene	Organism	Action	Source URL
BIMP105476	ABCB1B	Abcb1b	Mus musculus (house mouse)	Lithocholic acid results in increased expression of ABCB1B mRNA	https://ctdbase.org/detail.go?type=gene&acc=18669
BIMP105027	ABCB1B	Abcb1b	Homo sapiens (human)	Curcumin results in decreased expression of ABCB1B mRNA	https://ctdbase.org/detail.go?type=gene&acc=18669
BIMP105027	ABCB1B	Abcb1b	Mus musculus (house mouse)	2-(4-morpholinyl)-8-phenyl-4H-1-benzopyran-4-one promotes the reaction [curcumin results in decreased expression of ABCB1B protein]\|curcumin results in decreased expression of ABCB1B protein\|curcumin inhibits the reaction [[NFKB1 protein binds to RELA protein] which results in increased expression of ABCB1B mrna]\|curcumin results in decreased expression of ABCB1B mrna\|[curcumin results in decreased expression of ABCB1B protein] which results in increased susceptibility to doxorubicin	https://ctdbase.org/detail.go?type=gene&acc=18669
BIMP101295	ABCB1B	Abcb1b	Mus musculus (house mouse)	Diethylhexyl phthalate results in increased expression of ABCB1B mrna\|ppara protein promotes the reaction [diethylhexyl phthalate results in increased expression of ABCB1B mrna]	https://ctdbase.org/detail.go?type=gene&acc=18669
BIMP101295	ABCB1B	Abcb1b	Mus musculus (house mouse)	[tetrachlorodibenzodioxin co-treated with 2,4,5,2',4',5'-hexachlorobiphenyl co-treated with diethylhexyl phthalate co-treated with bisphenol A] results in increased expression of ABCB1B mRNA	https://ctdbase.org/detail.go?type=gene&acc=18669
BIMP101071	ABCB1B	Abcb1b	Rattus norvegicus (Norway rat)	Furan results in increased expression of ABCB1B mRNA	https://ctdbase.org/detail.go?type=gene&acc=18669
BIMP094277	ABCB1B	Abcb1b	Mus musculus (house mouse)	Bisphenol A results in decreased expression of ABCB1B mRNA	https://ctdbase.org/detail.go?type=gene&acc=18669
BIMP094277	ABCB1B	Abcb1b	Mus musculus (house mouse)	[tetrachlorodibenzodioxin co-treated with 2,4,5,2',4',5'-hexachlorobiphenyl co-treated with diethylhexyl phthalate co-treated with bisphenol A] results in increased expression of ABCB1B mRNA	https://ctdbase.org/detail.go?type=gene&acc=18669
BIMP094277	ABCB1B	Abcb1b	Rattus norvegicus (Norway rat)	Bisphenol A results in decreased expression of ABCB1B mRNA	https://ctdbase.org/detail.go?type=gene&acc=18669
BIMP094277	ABCB1B	Abcb1b	Rattus norvegicus (Norway rat)	Bisphenol A results in increased expression of ABCB1B mRNA	https://ctdbase.org/detail.go?type=gene&acc=18669
BIMP071726	ABCB1B	Abcb1b	Homo sapiens (human)	Diclofenac results in decreased expression of ABCB1B mrna\|diclofenac results in increased expression of ABCB1B mRNA	https://ctdbase.org/detail.go?type=gene&acc=18669
BIMP071166	ABCB1B	Abcb1b	Mus musculus (house mouse)	ABCB1B protein affects the uptake of digoxin	https://ctdbase.org/detail.go?type=gene&acc=18669
BIMP071247	ABCB1B	Abcb1b	Mus musculus (house mouse)	Ciprofibrate results in increased expression of ABCB1B mRNA	https://ctdbase.org/detail.go?type=gene&acc=18669
BIMP071736	ABCB1B	Abcb1b	Rattus norvegicus (Norway rat)	ABCB1B protein affects the uptake of quinine analog	https://ctdbase.org/detail.go?type=gene&acc=18669
BIMP071851	ABCB1B	Abcb1b	Mus musculus (house mouse)	[methionine deficiency co-treated with choline deficiency co-treated with folic acid deficiency] results in increased expression of ABCB1B mRNA	https://ctdbase.org/detail.go?type=gene&acc=18669
BIMP071851	ABCB1B	Abcb1b	Rattus norvegicus (Norway rat)	[methionine deficiency co-treated with choline deficiency] results in increased expression of ABCB1B mRNA	https://ctdbase.org/detail.go?type=gene&acc=18669
BIMP072262	ABCB1B	Abcb1b	Mus musculus (house mouse)	Tetrachloroethylene results in increased expression of ABCB1B mRNA	https://ctdbase.org/detail.go?type=gene&acc=18669
BIMP072300	ABCB1B	Abcb1b	Mus musculus (house mouse)	ABCB1B gene mutant form results in increased susceptibility to doxorubicin	https://ctdbase.org/detail.go?type=gene&acc=18669
BIMP072300	ABCB1B	Abcb1b	Mus musculus (house mouse)	ABCB1B protein affects the transport of doxorubicin	https://ctdbase.org/detail.go?type=gene&acc=18669
BIMP072300	ABCB1B	Abcb1b	Mus musculus (house mouse)	[curcumin results in decreased expression of ABCB1B protein] which results in increased susceptibility to doxorubicin	https://ctdbase.org/detail.go?type=gene&acc=18669
BIMP072300	ABCB1B	Abcb1b	Mus musculus (house mouse)	Lipopolysaccharides affects the reaction [ABCB1B protein results in increased secretion of doxorubicin]	https://ctdbase.org/detail.go?type=gene&acc=18669
BIMP072300	ABCB1B	Abcb1b	Rattus norvegicus (Norway rat)	Doxorubicin results in increased expression of ABCB1B mRNA	https://ctdbase.org/detail.go?type=gene&acc=18669
BIMP072300	ABCB1B	Abcb1b	Rattus norvegicus (Norway rat)	Doxorubicin results in increased expression of ABCB1B protein	https://ctdbase.org/detail.go?type=gene&acc=18669
BIMP072654	ABCB1B	Abcb1b	Rattus norvegicus (Norway rat)	[[ABCB1A gene mutant form co-treated with ABCB1B gene mutant form] affects the susceptibility to fluoxetine] which affects the abundance of olanzapine\|[[abcb1a gene mutant form co-treated with ABCB1B gene mutant form] affects the susceptibility to fluoxetine] which results in increased uptake of olanzapine\|[abcb1a gene mutant form co-treated with ABCB1B gene mutant form] affects the susceptibility to fluoxetine	https://ctdbase.org/detail.go?type=gene&acc=18669
BIMP072777	ABCB1B	Abcb1b	Rattus norvegicus (Norway rat)	Gentamicins results in increased expression of ABCB1B mRNA	https://ctdbase.org/detail.go?type=gene&acc=18669

BIMP105476

ABCB1B

Abcb1b

Mus musculus (house mouse)

Lithocholic acid results in increased expression of ABCB1B mRNA