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Interactions between compounds and specific gene/protein targets.
| BIMP_ID | Target Name | Gene | Organism | Action | Source URL |
|---|---|---|---|---|---|
|
ABCB11
|
Homo sapiens (human)
|
Pregna-4,17-diene-3,16-dione inhibits the reaction [alisol B 23-acetate results in increased expression of ABCB11 protein]|alisol B 23-acetate results in increased expression of ABCB11 protein
|
https://ctdbase.org/detail.go?type=gene&acc=8647
|
||
|
ABCB11
|
Mus musculus (house mouse)
|
Alisol B 23-acetate inhibits the reaction [ethinyl estradiol results in decreased expression of ABCB11 mrna]|alisol B 23-acetate inhibits the reaction [ethinyl estradiol results in decreased expression of ABCB11 protein]|pregna-4,17-diene-3,16-dione inhibits the reaction [alisol B 23-acetate inhibits the reaction [ethinyl estradiol results in decreased expression of ABCB11 mrna]]
|
https://ctdbase.org/detail.go?type=gene&acc=8647
|
||
|
ABCB11
|
Mus musculus (house mouse)
|
Alisol B 23-acetate promotes the reaction [1-naphthylisothiocyanate results in increased expression of ABCB11 protein]|alisol B 23-acetate promotes the reaction [1-naphthylisothiocyanate results in increased expression of ABCB11 mrna]|pregna-4,17-diene-3,16-dione inhibits the reaction [alisol B 23-acetate promotes the reaction [1-naphthylisothiocyanate results in increased expression of ABCB11 mrna]]
|
https://ctdbase.org/detail.go?type=gene&acc=8647
|
||
|
ABCB11
|
Mus musculus (house mouse)
|
Alisol B 23-acetate promotes the reaction [carbon tetrachloride results in increased expression of ABCB11 mrna]
|
https://ctdbase.org/detail.go?type=gene&acc=8647
|
||
|
ABCB11
|
Mus musculus (house mouse)
|
Alisol B 23-acetate results in increased expression of ABCB11 mrna|pregna-4,17-diene-3,16-dione inhibits the reaction [alisol B 23-acetate results in increased expression of ABCB11 mrna]
|
https://ctdbase.org/detail.go?type=gene&acc=8647
|
||
|
ABCB11
|
Mus musculus (house mouse)
|
Alisol B 23-acetate results in increased expression of ABCB11 protein
|
https://ctdbase.org/detail.go?type=gene&acc=8647
|
||
|
ABCB11
|
Mus musculus (house mouse)
|
[furan co-treated with rhodioloside] results in increased expression of ABCB11 mRNA
|
https://ctdbase.org/detail.go?type=gene&acc=8647
|
||
|
ABCB11
|
Homo sapiens (human)
|
Cryptotanshinone inhibits the reaction [ABCB11 protein results in increased transport of taurodeoxycholic acid]
|
https://ctdbase.org/detail.go?type=gene&acc=8647
|
||
|
ABCB11
|
Mus musculus (house mouse)
|
[vancomycin co-treated with imipenem] results in increased expression of ABCB11 mRNA
|
https://ctdbase.org/detail.go?type=gene&acc=8647
|
||
|
ABCB11
|
Mus musculus (house mouse)
|
[vancomycin co-treated with neomycin co-treated with ampicillin co-treated with metronidazole co-treated with amphotericin B] results in increased expression of ABCB11 mRNA
|
https://ctdbase.org/detail.go?type=gene&acc=8647
|
||
|
ABCB11
|
Homo sapiens (human)
|
Glycyrrhizic acid results in decreased activity of ABCB11 protein|glycyrrhizic acid inhibits the reaction [ABCB11 protein results in increased transport of taurocholic acid]
|
https://ctdbase.org/detail.go?type=gene&acc=8647
|
||
|
ABCB11
|
Mus musculus (house mouse)
|
[1-naphthylisothiocyanate co-treated with allopurinol] results in increased expression of ABCB11 mRNA
|
https://ctdbase.org/detail.go?type=gene&acc=8647
|
||
|
ABCB11
|
Homo sapiens (human)
|
Cholates results in decreased activity of ABCB11 protein|cholates inhibits the reaction [ABCB11 protein results in increased transport of taurocholic acid]|cholic acid results in decreased activity of ABCB11 protein|cholic acid inhibits the reaction [ABCB11 protein results in increased transport of taurocholic acid]
|
https://ctdbase.org/detail.go?type=gene&acc=8647
|
||
|
ABCB11
|
Homo sapiens (human)
|
Cholates results in increased expression of ABCB11 mRNA
|
https://ctdbase.org/detail.go?type=gene&acc=8647
|
||
|
ABCB11
|
Rattus
|
ABCB11 protein affects the transport of cholates
|
https://ctdbase.org/detail.go?type=gene&acc=8647
|
||
|
ABCB11
|
Homo sapiens (human)
|
|
https://www.dgidb.org/genes/hgnc:42
|
||
|
ABCB11
|
Gallus gallus (chicken)
|
[T-2 toxin co-treated with cholic acid] affects the expression of ABCB11 mrna|cholic acid results in increased expression of ABCB11 mRNA
|
https://ctdbase.org/detail.go?type=gene&acc=8647
|
||
|
ABCB11
|
Homo sapiens (human)
|
Cholic acid results in increased expression of ABCB11 mRNA
|
https://ctdbase.org/detail.go?type=gene&acc=8647
|
||
|
ABCB11
|
Mus musculus (house mouse)
|
[cholic acid binds to and results in increased activity of NR1H4 protein] which results in increased expression of ABCB11 mRNA
|
https://ctdbase.org/detail.go?type=gene&acc=8647
|
||
|
ABCB11
|
Mus musculus (house mouse)
|
Cholic acid results in increased expression of ABCB11 mRNA
|
https://ctdbase.org/detail.go?type=gene&acc=8647
|
||
|
ABCB11
|
Mus musculus (house mouse)
|
Cholic acid results in increased expression of ABCB11 protein
|
https://ctdbase.org/detail.go?type=gene&acc=8647
|
||
|
ABCB11
|
Mus musculus (house mouse)
|
Epiallopregnanolone sulfate inhibits the reaction [cholic acid results in increased expression of ABCB11 mrna]
|
https://ctdbase.org/detail.go?type=gene&acc=8647
|
||
|
ABCB11
|
Mus musculus (house mouse)
|
[NR1H4 protein mutant form inhibits the reaction [cholic acid results in increased phosphorylation of NR1H4 protein]] which results in decreased expression of ABCB11 mRNA
|
https://ctdbase.org/detail.go?type=gene&acc=8647
|
||
|
ABCB11
|
Rattus norvegicus (Norway rat)
|
[cholesterol, dietary co-treated with cholic acid] results in increased expression of ABCB11 mrna|cholic acid results in increased expression of ABCB11 mRNA
|
https://ctdbase.org/detail.go?type=gene&acc=8647
|
||
|
ABCB11
|
Homo sapiens (human)
|
Deoxycholic acid results in increased expression of ABCB11 mRNA
|
https://ctdbase.org/detail.go?type=gene&acc=8647
|
No matching records found on this page.