SCFBio, IIT Delhi
Hauz Khas, New Delhi
BIMP
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SCFBio, IIT Delhi
Interactions between compounds and specific gene/protein targets.
| BIMP_ID | Target Name | Gene | Organism | Action | Source URL |
|---|---|---|---|---|---|
|
ABCB11
|
Homo sapiens (human)
|
Triptolide results in decreased expression of ABCB11 protein
|
https://ctdbase.org/detail.go?type=gene&acc=8647
|
||
|
ABCB11
|
Mus musculus (house mouse)
|
[triptolide co-treated with lipopolysaccharides] results in decreased expression of ABCB11 protein|obeticholic acid inhibits the reaction [[triptolide co-treated with lipopolysaccharides] results in decreased expression of ABCB11 protein]
|
https://ctdbase.org/detail.go?type=gene&acc=8647
|
||
|
ABCB11
|
Mus musculus (house mouse)
|
Triptolide results in decreased expression of ABCB11 mRNA
|
https://ctdbase.org/detail.go?type=gene&acc=8647
|
||
|
ABCB11
|
Rattus norvegicus (Norway rat)
|
Triptolide results in increased expression of ABCB11 protein
|
https://ctdbase.org/detail.go?type=gene&acc=8647
|
||
|
ABCB11
|
Rattus norvegicus (Norway rat)
|
Taurine results in increased expression of ABCB11 protein
|
https://ctdbase.org/detail.go?type=gene&acc=8647
|
||
|
ABCB11
|
Mus musculus (house mouse)
|
U 0126 inhibits the reaction [oleanolic acid results in decreased expression of ABCB11 mrna]|dorsomorphin inhibits the reaction [oleanolic acid results in decreased expression of ABCB11 mrna]|dorsomorphin inhibits the reaction [oleanolic acid results in decreased expression of ABCB11 protein]|prkaa1 protein affects the reaction [oleanolic acid results in decreased expression of ABCB11 mrna]
|
https://ctdbase.org/detail.go?type=gene&acc=8647
|
||
|
ABCB11
|
Mus musculus (house mouse)
|
HNF1A protein affects the reaction [SRT1720 inhibits the reaction [oleanolic acid results in decreased expression of ABCB11 protein]]|srt1720 inhibits the reaction [oleanolic acid results in decreased expression of ABCB11 mrna]|srt1720 inhibits the reaction [oleanolic acid results in decreased expression of ABCB11 protein]|gw 4064 inhibits the reaction [oleanolic acid results in decreased expression of ABCB11 mrna]|gw 4064 inhibits the reaction [oleanolic acid results in decreased expression of ABCB11 protein]
|
https://ctdbase.org/detail.go?type=gene&acc=8647
|
||
|
ABCB11
|
Mus musculus (house mouse)
|
Oleanolic acid results in decreased expression of ABCB11 mrna|oleanolic acid results in decreased expression of ABCB11 protein
|
https://ctdbase.org/detail.go?type=gene&acc=8647
|
||
|
ABCB11
|
Homo sapiens (human)
|
[catechin co-treated with grape seed proanthocyanidins] results in increased expression of ABCB11 mRNA
|
https://ctdbase.org/detail.go?type=gene&acc=8647
|
||
|
ABCB11
|
Homo sapiens (human)
|
Epicatechin gallate results in increased expression of ABCB11 mRNA
|
https://ctdbase.org/detail.go?type=gene&acc=8647
|
||
|
ABCB11
|
Mus musculus (house mouse)
|
Dorsomorphin inhibits the reaction [emodin results in decreased expression of ABCB11 mrna]
|
https://ctdbase.org/detail.go?type=gene&acc=8647
|
||
|
ABCB11
|
Mus musculus (house mouse)
|
Dorsomorphin inhibits the reaction [oleanolic acid results in decreased expression of ABCB11 mrna]|dorsomorphin inhibits the reaction [oleanolic acid results in decreased expression of ABCB11 protein]
|
https://ctdbase.org/detail.go?type=gene&acc=8647
|
||
|
ABCB11
|
Rattus norvegicus (Norway rat)
|
Dorsomorphin inhibits the reaction [1-naphthylisothiocyanate results in decreased expression of ABCB11 mrna]|dorsomorphin inhibits the reaction [1-naphthylisothiocyanate results in decreased expression of ABCB11 protein]
|
https://ctdbase.org/detail.go?type=gene&acc=8647
|
||
|
ABCB11
|
Rattus norvegicus (Norway rat)
|
Dorsomorphin inhibits the reaction [ethinyl estradiol results in decreased expression of ABCB11 protein]|dorsomorphin inhibits the reaction [ethinyl estradiol results in decreased expression of ABCB11 mrna]
|
https://ctdbase.org/detail.go?type=gene&acc=8647
|
||
|
ABCB11
|
Mus musculus (house mouse)
|
[1-naphthylisothiocyanate co-treated with uric acid] results in increased expression of ABCB11 mRNA
|
https://ctdbase.org/detail.go?type=gene&acc=8647
|
||
|
ABCB11
|
Rattus norvegicus (Norway rat)
|
Dioscin promotes the reaction [1-naphthylisothiocyanate results in increased expression of ABCB11 mrna]|dioscin promotes the reaction [1-naphthylisothiocyanate results in increased expression of ABCB11 protein]
|
https://ctdbase.org/detail.go?type=gene&acc=8647
|
||
|
ABCB11
|
Homo sapiens (human)
|
Erythromycin results in decreased activity of ABCB11 protein|erythromycin inhibits the reaction [ABCB11 protein results in increased transport of taurocholic acid]
|
https://ctdbase.org/detail.go?type=gene&acc=8647
|
||
|
ABCB11
|
Homo sapiens (human)
|
Vinblastine inhibits the reaction [ABCB11 protein results in increased transport of taurocholic acid]|vinblastine results in decreased activity of ABCB11 protein
|
https://ctdbase.org/detail.go?type=gene&acc=8647
|
||
|
ABCB11
|
Mus musculus (house mouse)
|
ABCB11 protein results in increased export of vinblastine|abcb11 protein results in decreased uptake of vinblastine
|
https://ctdbase.org/detail.go?type=gene&acc=8647
|
||
|
ABCB11
|
Mus musculus (house mouse)
|
8-epidiosbulbin E acetate results in decreased expression of ABCB11 protein
|
https://ctdbase.org/detail.go?type=gene&acc=8647
|
||
|
ABCB11
|
Homo sapiens (human)
|
Enzymes and coenzymes inhibits the reaction [celastrol inhibits the reaction [ABCB11 protein results in increased transport of taurodeoxycholic acid]]|celastrol inhibits the reaction [ABCB11 protein results in increased transport of taurodeoxycholic acid]
|
https://ctdbase.org/detail.go?type=gene&acc=8647
|
||
|
ABCB11
|
Mus musculus (house mouse)
|
[methionine deficiency co-treated with choline deficiency co-treated with folic acid deficiency] results in decreased expression of ABCB11 mRNA
|
https://ctdbase.org/detail.go?type=gene&acc=8647
|
||
|
ABCB11
|
Homo sapiens (human)
|
Vitamin E results in decreased expression of ABCB11 mRNA
|
https://ctdbase.org/detail.go?type=gene&acc=8647
|
||
|
ABCB11
|
Homo sapiens (human)
|
Naproxen inhibits the reaction [ABCB11 protein results in increased transport of taurocholic acid]|naproxen results in decreased activity of ABCB11 protein
|
https://ctdbase.org/detail.go?type=gene&acc=8647
|
||
|
ABCB11
|
Homo sapiens (human)
|
Aurantio-obtusin inhibits the reaction [ABCB11 protein results in increased transport of taurodeoxycholic acid]
|
https://ctdbase.org/detail.go?type=gene&acc=8647
|
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