Molecular Targets : Dataset Browser

BIMP_ID	Target Name	Gene	Organism	Action	Source URL
BIMP038077	ABCB1	ABCB1	Homo sapiens (human)	Isovitexin inhibits the reaction [ABCB1 protein results in decreased uptake of daunorubicin]\|isovitexin promotes the reaction [elacridar inhibits the reaction [ABCB1 protein results in decreased uptake of rhodamine 123]]	https://ctdbase.org/detail.go?type=gene&acc=5243
BIMP063204	ABCB1	ABCB1	Homo sapiens (human)	Glaucine results in increased activity of ABCB1 protein	https://ctdbase.org/detail.go?type=gene&acc=5243
BIMP059909	ABCB1	ABCB1	Homo sapiens (human)	Diallyl trisulfide results in decreased expression of ABCB1 protein	https://ctdbase.org/detail.go?type=gene&acc=5243
BIMP059909	ABCB1	ABCB1	Homo sapiens (human)	Diallyl trisulfide results in increased expression of ABCB1 mRNA	https://ctdbase.org/detail.go?type=gene&acc=5243
BIMP062983	ABCB1	ABCB1	Homo sapiens (human)	Diallyl disulfide results in increased expression of ABCB1 mRNA	https://ctdbase.org/detail.go?type=gene&acc=5243
BIMP037098	ABCB1	ABCB1	Homo sapiens (human)	Ar-turmerone results in increased expression of ABCB1 mRNA	https://ctdbase.org/detail.go?type=gene&acc=5243
BIMP037221	ABCB1	ABCB1	Homo sapiens (human)		https://www.dgidb.org/genes/hgnc:40
BIMP037775	ABCB1	ABCB1	Homo sapiens (human)	Dihydromyricetin inhibits the reaction [ABCB1 protein results in decreased uptake of daunorubicin]	https://ctdbase.org/detail.go?type=gene&acc=5243
BIMP064321	ABCB1	ABCB1	Homo sapiens (human)		https://www.dgidb.org/genes/hgnc:40
BIMP030937	ABCB1	ABCB1	Homo sapiens (human)	Sinensetin analog inhibits the reaction [ABCB1 protein results in increased transport of digoxin]\|sinensetin analog results in decreased activity of ABCB1 protein\|sinensetin inhibits the reaction [ABCB1 protein results in increased transport of digoxin]\|sinensetin results in decreased activity of ABCB1 protein	https://ctdbase.org/detail.go?type=gene&acc=5243
BIMP031809	ABCB1	ABCB1	Homo sapiens (human)	[phyllodulcin affects the activity of ABCB1 protein] which results in increased abundance of daunorubicin	https://ctdbase.org/detail.go?type=gene&acc=5243
BIMP032227	ABCB1	ABCB1	Homo sapiens (human)	ABCB1 gene polymorphism affects the susceptibility to docetaxel	https://ctdbase.org/detail.go?type=gene&acc=5243
BIMP032227	ABCB1	ABCB1	Homo sapiens (human)	ABCB1 mRNA results in increased susceptibility to docetaxel	https://ctdbase.org/detail.go?type=gene&acc=5243
BIMP032227	ABCB1	ABCB1	Homo sapiens (human)	ABCB1 protein affects the reaction [EGFR protein results in decreased susceptibility to docetaxel]	https://ctdbase.org/detail.go?type=gene&acc=5243
BIMP032227	ABCB1	ABCB1	Homo sapiens (human)	ABCB1 protein results in decreased susceptibility to docetaxel	https://ctdbase.org/detail.go?type=gene&acc=5243
BIMP032227	ABCB1	ABCB1	Homo sapiens (human)	Cinchonine analog inhibits the reaction [ABCB1 protein results in decreased susceptibility to docetaxel]\|quinidine inhibits the reaction [ABCB1 protein results in decreased susceptibility to docetaxel]\|cinchonine inhibits the reaction [ABCB1 protein results in decreased susceptibility to docetaxel]	https://ctdbase.org/detail.go?type=gene&acc=5243
BIMP032227	ABCB1	ABCB1	Homo sapiens (human)	Docetaxel analog binds to ABCB1 protein\|docetaxel binds to ABCB1 protein	https://ctdbase.org/detail.go?type=gene&acc=5243
BIMP032227	ABCB1	ABCB1	Homo sapiens (human)	[docetaxel results in increased expression of TP53 mrna] which results in decreased expression of ABCB1 mrna\|tp53 protein affects the reaction [docetaxel results in decreased expression of ABCB1 mrna]\|docetaxel results in decreased expression of ABCB1 mRNA	https://ctdbase.org/detail.go?type=gene&acc=5243
BIMP032227	ABCB1	ABCB1	Homo sapiens (human)	[docetaxel results in decreased susceptibility to docetaxel] which results in increased expression of ABCB1 protein\|[docetaxel results in decreased susceptibility to docetaxel] which results in increased expression of ABCB1 mRNA	https://ctdbase.org/detail.go?type=gene&acc=5243
BIMP032227	ABCB1	ABCB1	Homo sapiens (human)	[docetaxel results in increased activity of NR1I2 protein] which results in increased expression of ABCB1 mrna\|nr1i2 protein promotes the reaction [docetaxel results in increased expression of and results in increased activity of ABCB1 protein]	https://ctdbase.org/detail.go?type=gene&acc=5243
BIMP032227	ABCB1	ABCB1	Homo sapiens (human)	Docetaxel results in increased expression of ABCB1 mRNA	https://ctdbase.org/detail.go?type=gene&acc=5243
BIMP032227	ABCB1	ABCB1	Homo sapiens (human)	Docetaxel results in increased expression of ABCB1 protein	https://ctdbase.org/detail.go?type=gene&acc=5243
BIMP032227	ABCB1	ABCB1	Homo sapiens (human)	Pinostrobin inhibits the reaction [ABCB1 protein results in decreased susceptibility to docetaxel]\|tectochrysin inhibits the reaction [ABCB1 protein results in decreased susceptibility to docetaxel]	https://ctdbase.org/detail.go?type=gene&acc=5243
BIMP032228	ABCB1	ABCB1	Homo sapiens (human)		https://www.dgidb.org/genes/hgnc:40
BIMP035095	ABCB1	ABCB1	Homo sapiens (human)	10-deacetylpaclitaxel binds to ABCB1 protein	https://ctdbase.org/detail.go?type=gene&acc=5243

BIMP038077

ABCB1

Homo sapiens (human)

Isovitexin inhibits the reaction [ABCB1 protein results in decreased uptake of daunorubicin]|isovitexin promotes the reaction [elacridar inhibits the reaction [ABCB1 protein results in decreased uptake of rhodamine 123]]

https://ctdbase.org/detail.go?type=gene&acc=5243

BIMP063204

ABCB1

Homo sapiens (human)

Glaucine results in increased activity of ABCB1 protein

https://ctdbase.org/detail.go?type=gene&acc=5243

BIMP059909

ABCB1

Homo sapiens (human)

Diallyl trisulfide results in decreased expression of ABCB1 protein

https://ctdbase.org/detail.go?type=gene&acc=5243

BIMP059909

ABCB1

Homo sapiens (human)

Diallyl trisulfide results in increased expression of ABCB1 mRNA

https://ctdbase.org/detail.go?type=gene&acc=5243

BIMP062983

ABCB1

Homo sapiens (human)

Diallyl disulfide results in increased expression of ABCB1 mRNA

https://ctdbase.org/detail.go?type=gene&acc=5243

BIMP037098

ABCB1

Homo sapiens (human)

Ar-turmerone results in increased expression of ABCB1 mRNA

https://ctdbase.org/detail.go?type=gene&acc=5243

BIMP037221

ABCB1

Homo sapiens (human)

https://www.dgidb.org/genes/hgnc:40

BIMP037775

ABCB1

Homo sapiens (human)

Dihydromyricetin inhibits the reaction [ABCB1 protein results in decreased uptake of daunorubicin]

https://ctdbase.org/detail.go?type=gene&acc=5243

BIMP064321

ABCB1

Homo sapiens (human)

https://www.dgidb.org/genes/hgnc:40

BIMP030937

ABCB1

Homo sapiens (human)

Sinensetin analog inhibits the reaction [ABCB1 protein results in increased transport of digoxin]|sinensetin analog results in decreased activity of ABCB1 protein|sinensetin inhibits the reaction [ABCB1 protein results in increased transport of digoxin]|sinensetin results in decreased activity of ABCB1 protein

https://ctdbase.org/detail.go?type=gene&acc=5243

BIMP031809

ABCB1

Homo sapiens (human)

[phyllodulcin affects the activity of ABCB1 protein] which results in increased abundance of daunorubicin

https://ctdbase.org/detail.go?type=gene&acc=5243

BIMP032227

ABCB1

Homo sapiens (human)

ABCB1 gene polymorphism affects the susceptibility to docetaxel

https://ctdbase.org/detail.go?type=gene&acc=5243

BIMP032227

ABCB1

Homo sapiens (human)

ABCB1 mRNA results in increased susceptibility to docetaxel

https://ctdbase.org/detail.go?type=gene&acc=5243

BIMP032227

ABCB1

Homo sapiens (human)

ABCB1 protein affects the reaction [EGFR protein results in decreased susceptibility to docetaxel]

https://ctdbase.org/detail.go?type=gene&acc=5243

BIMP032227

ABCB1

Homo sapiens (human)

ABCB1 protein results in decreased susceptibility to docetaxel

https://ctdbase.org/detail.go?type=gene&acc=5243

BIMP032227

ABCB1

Homo sapiens (human)

Cinchonine analog inhibits the reaction [ABCB1 protein results in decreased susceptibility to docetaxel]|quinidine inhibits the reaction [ABCB1 protein results in decreased susceptibility to docetaxel]|cinchonine inhibits the reaction [ABCB1 protein results in decreased susceptibility to docetaxel]

https://ctdbase.org/detail.go?type=gene&acc=5243

BIMP032227

ABCB1

Homo sapiens (human)

Docetaxel analog binds to ABCB1 protein|docetaxel binds to ABCB1 protein

https://ctdbase.org/detail.go?type=gene&acc=5243

BIMP032227

ABCB1

Homo sapiens (human)

[docetaxel results in increased expression of TP53 mrna] which results in decreased expression of ABCB1 mrna|tp53 protein affects the reaction [docetaxel results in decreased expression of ABCB1 mrna]|docetaxel results in decreased expression of ABCB1 mRNA

https://ctdbase.org/detail.go?type=gene&acc=5243

BIMP032227

ABCB1

Homo sapiens (human)

[docetaxel results in decreased susceptibility to docetaxel] which results in increased expression of ABCB1 protein|[docetaxel results in decreased susceptibility to docetaxel] which results in increased expression of ABCB1 mRNA

https://ctdbase.org/detail.go?type=gene&acc=5243

BIMP032227

ABCB1

Homo sapiens (human)

[docetaxel results in increased activity of NR1I2 protein] which results in increased expression of ABCB1 mrna|nr1i2 protein promotes the reaction [docetaxel results in increased expression of and results in increased activity of ABCB1 protein]

https://ctdbase.org/detail.go?type=gene&acc=5243

BIMP032227

ABCB1

Homo sapiens (human)

Docetaxel results in increased expression of ABCB1 mRNA

https://ctdbase.org/detail.go?type=gene&acc=5243

BIMP032227

ABCB1

Homo sapiens (human)

Docetaxel results in increased expression of ABCB1 protein

https://ctdbase.org/detail.go?type=gene&acc=5243

BIMP032227

ABCB1

Homo sapiens (human)

Pinostrobin inhibits the reaction [ABCB1 protein results in decreased susceptibility to docetaxel]|tectochrysin inhibits the reaction [ABCB1 protein results in decreased susceptibility to docetaxel]

https://ctdbase.org/detail.go?type=gene&acc=5243

BIMP032228

ABCB1

Homo sapiens (human)

https://www.dgidb.org/genes/hgnc:40

BIMP035095

ABCB1

Homo sapiens (human)

10-deacetylpaclitaxel binds to ABCB1 protein

https://ctdbase.org/detail.go?type=gene&acc=5243