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Interactions between compounds and specific gene/protein targets.
| BIMP_ID | Target Name | Gene | Organism | Action | Source URL |
|---|---|---|---|---|---|
|
ABCB1
|
Homo sapiens (human)
|
Naproxen affects the expression of ABCB1 mRNA
|
https://ctdbase.org/detail.go?type=gene&acc=5243
|
||
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ABCB1
|
Homo sapiens (human)
|
ABCB1 protein results in increased transport of digoxigenin
|
https://ctdbase.org/detail.go?type=gene&acc=5243
|
||
|
ABCB1
|
Homo sapiens (human)
|
Capsaicin results in increased expression of ABCB1 mrna|capsaicin affects the reaction [ABCB1 protein results in increased export of digoxin]|capsaicin results in increased expression of ABCB1 protein
|
https://ctdbase.org/detail.go?type=gene&acc=5243
|
||
|
ABCB1
|
Homo sapiens (human)
|
|
https://www.dgidb.org/genes/hgnc:40
|
||
|
ABCB1
|
Homo sapiens (human)
|
Aurapten promotes the reaction [ABCB1 protein results in increased import of daunorubicin]|aurapten promotes the reaction [ABCB1 protein results in increased hydrolysis of adenosine triphosphate]
|
https://ctdbase.org/detail.go?type=gene&acc=5243
|
||
|
ABCB1
|
Homo sapiens (human)
|
Evodiamine inhibits the reaction [TNF protein results in increased expression of ABCB1 protein]
|
https://ctdbase.org/detail.go?type=gene&acc=5243
|
||
|
ABCB1
|
Homo sapiens (human)
|
|
https://www.dgidb.org/genes/hgnc:40
|
||
|
ABCB1
|
Homo sapiens (human)
|
Vancomycin results in decreased expression of and affects the localization of ABCB1 protein|cilastatin inhibits the reaction [vancomycin results in decreased expression of and affects the localization of ABCB1 protein]
|
https://ctdbase.org/detail.go?type=gene&acc=5243
|
||
|
ABCB1
|
Homo sapiens (human)
|
Rhodioloside affects the reaction [ABCB1 protein results in increased transport of digoxin]
|
https://ctdbase.org/detail.go?type=gene&acc=5243
|
||
|
ABCB1
|
Homo sapiens (human)
|
|
https://www.dgidb.org/genes/hgnc:40
|
||
|
ABCB1
|
Homo sapiens (human)
|
Aflatoxin B1 results in decreased methylation of ABCB1 gene|aflatoxin B1 results in increased expression of ABCB1 mRNA
|
https://ctdbase.org/detail.go?type=gene&acc=5243
|
||
|
ABCB1
|
Homo sapiens (human)
|
Aflatoxin B1 results in increased methylation of ABCB1 intron
|
https://ctdbase.org/detail.go?type=gene&acc=5243
|
||
|
ABCB1
|
Rattus norvegicus (Norway rat)
|
Sildenafil citrate inhibits the reaction [[aflatoxin B1 co-treated with ethanol] results in increased expression of ABCB1 mrna]|[aflatoxin B1 co-treated with ethanol] results in increased expression of ABCB1 mRNA
|
https://ctdbase.org/detail.go?type=gene&acc=5243
|
||
|
ABCB1
|
Homo sapiens (human)
|
|
https://www.dgidb.org/genes/hgnc:40
|
||
|
ABCB1
|
Homo sapiens (human)
|
Demecolcine inhibits the reaction [verapamil analog results in increased activity of ABCB1 protein mutant form]|demecolcine results in increased activity of ABCB1 protein mutant form
|
https://ctdbase.org/detail.go?type=gene&acc=5243
|
||
|
ABCB1
|
Homo sapiens (human)
|
Troleandomycin inhibits the reaction [ABCB1 protein results in increased secretion of fluorexon]|troleandomycin inhibits the reaction [ABCB1 protein results in increased secretion of vinblastine]
|
https://ctdbase.org/detail.go?type=gene&acc=5243
|
||
|
ABCB10
|
Homo sapiens (human)
|
Aflatoxin B1 results in increased methylation of ABCB10 intron
|
https://ctdbase.org/detail.go?type=gene&acc=23456
|
||
|
ABCB10
|
Rattus norvegicus (Norway rat)
|
Aflatoxin B1 results in decreased expression of ABCB10 mRNA
|
https://ctdbase.org/detail.go?type=gene&acc=23456
|
||
|
ABCB10
|
Homo sapiens (human)
|
Atrazine results in decreased expression of ABCB10 mRNA
|
https://ctdbase.org/detail.go?type=gene&acc=23456
|
||
|
ABCB10
|
Homo sapiens (human)
|
Aristolochic acid I results in decreased expression of ABCB10 mRNA
|
https://ctdbase.org/detail.go?type=gene&acc=23456
|
||
|
ABCB10
|
Mus musculus (house mouse)
|
[methionine deficiency co-treated with choline deficiency co-treated with folic acid deficiency] results in decreased expression of ABCB10 mRNA
|
https://ctdbase.org/detail.go?type=gene&acc=23456
|
||
|
ABCB10
|
Homo sapiens (human)
|
Abrine results in decreased expression of ABCB10 mRNA
|
https://ctdbase.org/detail.go?type=gene&acc=23456
|
||
|
ABCB10
|
Mus musculus (house mouse)
|
[perfluorooctane sulfonic acid co-treated with cellulose] results in decreased expression of ABCB10 mRNA
|
https://ctdbase.org/detail.go?type=gene&acc=23456
|
||
|
ABCB10
|
Rattus norvegicus (Norway rat)
|
Acetamide results in decreased expression of ABCB10 mRNA
|
https://ctdbase.org/detail.go?type=gene&acc=23456
|
||
|
ABCB10
|
Homo sapiens (human)
|
Calcitriol results in decreased expression of ABCB10 mRNA
|
https://ctdbase.org/detail.go?type=gene&acc=23456
|
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