Molecular Targets : Dataset Browser

BIMP_ID	Target Name	Gene	Organism	Action	Source URL
BIMP025809	ABCB1	ABCB1	Homo sapiens (human)		https://www.dgidb.org/genes/hgnc:40
BIMP022174	ABCB1	ABCB1	Homo sapiens (human)	Erythromycin inhibits the reaction [ABCB1 protein results in increased secretion of vinblastine]	https://ctdbase.org/detail.go?type=gene&acc=5243
BIMP022174	ABCB1	ABCB1	Homo sapiens (human)	Erythromycin inhibits the reaction [ABCB1 protein results in increased transport of quinidinium]	https://ctdbase.org/detail.go?type=gene&acc=5243
BIMP022174	ABCB1	ABCB1	Rattus norvegicus (Norway rat)	ABCB1 protein affects the transport of erythromycin	https://ctdbase.org/detail.go?type=gene&acc=5243
BIMP022174	ABCB1	ABCB1	Homo sapiens (human)	Erythromycin results in decreased activity of ABCB1 protein	https://ctdbase.org/detail.go?type=gene&acc=5243
BIMP022174	ABCB1	ABCB1	Homo sapiens (human)		https://www.dgidb.org/genes/hgnc:40
BIMP022826	ABCB1	ABCB1	Homo sapiens (human)	Erythrosine results in decreased activity of ABCB1 protein	https://ctdbase.org/detail.go?type=gene&acc=5243
BIMP021585	ABCB1	ABCB1	Homo sapiens (human)	[glabridin affects the activity of ABCB1 protein] which results in increased abundance of daunorubicin	https://ctdbase.org/detail.go?type=gene&acc=5243
BIMP021632	ABCB1	ABCB1	Homo sapiens (human)	Dorsomorphin inhibits the reaction [rubimaillin results in decreased expression of ABCB1 mrna]\|rubimaillin inhibits the reaction [RELA protein results in increased expression of ABCB1 protein]\|rubimaillin results in decreased expression of ABCB1 mrna\|rubimaillin results in decreased expression of ABCB1 protein	https://ctdbase.org/detail.go?type=gene&acc=5243
BIMP022067	ABCB1	ABCB1	Homo sapiens (human)	Glutathione inhibits the reaction [hydrogen peroxide affects the expression of ABCB1 mrna]\|glutathione inhibits the reaction [ethanol results in increased expression of ABCB1 mrna]\|glutathione inhibits the reaction [doxorubicin results in increased expression of ABCB1 mrna]	https://ctdbase.org/detail.go?type=gene&acc=5243
BIMP022067	ABCB1	ABCB1	Homo sapiens (human)	Glutathione inhibits the reaction [titanium dioxide results in increased expression of ABCB1 mrna]	https://ctdbase.org/detail.go?type=gene&acc=5243
BIMP016724	ABCB1	ABCB1	Homo sapiens (human)	Dorsomorphin inhibits the reaction [rubimaillin results in decreased expression of ABCB1 mrna]	https://ctdbase.org/detail.go?type=gene&acc=5243
BIMP017089	ABCB1	ABCB1	Homo sapiens (human)	Allyl sulfide results in increased expression of ABCB1 mRNA	https://ctdbase.org/detail.go?type=gene&acc=5243
BIMP017190	ABCB1	ABCB1	Homo sapiens (human)	Protoapigenone analog results in decreased expression of ABCB1 protein	https://ctdbase.org/detail.go?type=gene&acc=5243
BIMP017628	ABCB1	ABCB1	Homo sapiens (human)	4-cumylphenol results in increased expression of ABCB1 mRNA	https://ctdbase.org/detail.go?type=gene&acc=5243
BIMP013162	ABCB1	ABCB1	Homo sapiens (human)	Deoxyglucose inhibits the reaction [ABCB1 protein results in increased export of diazinon]	https://ctdbase.org/detail.go?type=gene&acc=5243
BIMP015925	ABCB1	ABCB1	Homo sapiens (human)	3-hydroxyflavone results in increased expression of ABCB1 mRNA	https://ctdbase.org/detail.go?type=gene&acc=5243
BIMP016143	ABCB1	ABCB1	Rattus norvegicus (Norway rat)	Toluene affects the expression of ABCB1 mRNA	https://ctdbase.org/detail.go?type=gene&acc=5243
BIMP011758	ABCB1	ABCB1	Homo sapiens (human)	Abietic acid inhibits the reaction [ABCB1 protein results in increased uptake of digoxin]	https://ctdbase.org/detail.go?type=gene&acc=5243
BIMP007782	ABCB1	ABCB1	Homo sapiens (human)	Cepharanthine results in decreased activity of ABCB1 protein	https://ctdbase.org/detail.go?type=gene&acc=5243
BIMP001962	ABCB1	ABCB1	Homo sapiens (human)	Glycyrrhetinic acid inhibits the reaction [ABCB1 protein results in increased uptake of digoxin]	https://ctdbase.org/detail.go?type=gene&acc=5243
BIMP001962	ABCB1	ABCB1	Homo sapiens (human)	Glycyrrhetinic acid inhibits the reaction [verapamil results in increased activity of ABCB1 protein]\|[glycyrrhetinic acid affects the activity of ABCB1 protein] which results in increased abundance of daunorubicin\|[glycyrrhetinic acid affects the activity of ABCB1 protein] which affects the susceptibility to vinblastine	https://ctdbase.org/detail.go?type=gene&acc=5243
BIMP011298	ABCB1	ABCB1	Homo sapiens (human)	Butyrates results in increased expression of ABCB1 mRNA	https://ctdbase.org/detail.go?type=gene&acc=5243
BIMP012327	ABCB1	ABCB1	Homo sapiens (human)	Flavone results in increased activity of ABCB1 protein\|flavone promotes the reaction [elacridar inhibits the reaction [ABCB1 protein results in decreased uptake of daunorubicin]]\|flavone results in decreased expression of ABCB1 protein\|flavone inhibits the reaction [ABCB1 protein results in decreased uptake of rhodamine 123]\|flavone inhibits the reaction [ABCB1 protein results in decreased uptake of daunorubicin]	https://ctdbase.org/detail.go?type=gene&acc=5243
BIMP016421	ABCB1	ABCB1	Homo sapiens (human)	Terpinolene inhibits the reaction [ABCB1 protein results in increased uptake of digoxin]	https://ctdbase.org/detail.go?type=gene&acc=5243

BIMP025809

ABCB1

Homo sapiens (human)

https://www.dgidb.org/genes/hgnc:40

BIMP022174

ABCB1

Homo sapiens (human)

Erythromycin inhibits the reaction [ABCB1 protein results in increased secretion of vinblastine]

https://ctdbase.org/detail.go?type=gene&acc=5243

BIMP022174

ABCB1

Homo sapiens (human)

Erythromycin inhibits the reaction [ABCB1 protein results in increased transport of quinidinium]

https://ctdbase.org/detail.go?type=gene&acc=5243

BIMP022174

ABCB1

Rattus norvegicus (Norway rat)

ABCB1 protein affects the transport of erythromycin

https://ctdbase.org/detail.go?type=gene&acc=5243

BIMP022174

ABCB1

Homo sapiens (human)

Erythromycin results in decreased activity of ABCB1 protein

https://ctdbase.org/detail.go?type=gene&acc=5243

BIMP022174

ABCB1

Homo sapiens (human)

https://www.dgidb.org/genes/hgnc:40

BIMP022826

ABCB1

Homo sapiens (human)

Erythrosine results in decreased activity of ABCB1 protein

https://ctdbase.org/detail.go?type=gene&acc=5243

BIMP021585

ABCB1

Homo sapiens (human)

[glabridin affects the activity of ABCB1 protein] which results in increased abundance of daunorubicin

https://ctdbase.org/detail.go?type=gene&acc=5243

BIMP021632

ABCB1

Homo sapiens (human)

Dorsomorphin inhibits the reaction [rubimaillin results in decreased expression of ABCB1 mrna]|rubimaillin inhibits the reaction [RELA protein results in increased expression of ABCB1 protein]|rubimaillin results in decreased expression of ABCB1 mrna|rubimaillin results in decreased expression of ABCB1 protein

https://ctdbase.org/detail.go?type=gene&acc=5243

BIMP022067

ABCB1

Homo sapiens (human)

Glutathione inhibits the reaction [hydrogen peroxide affects the expression of ABCB1 mrna]|glutathione inhibits the reaction [ethanol results in increased expression of ABCB1 mrna]|glutathione inhibits the reaction [doxorubicin results in increased expression of ABCB1 mrna]

https://ctdbase.org/detail.go?type=gene&acc=5243

BIMP022067

ABCB1

Homo sapiens (human)

Glutathione inhibits the reaction [titanium dioxide results in increased expression of ABCB1 mrna]

https://ctdbase.org/detail.go?type=gene&acc=5243

BIMP016724

ABCB1

Homo sapiens (human)

Dorsomorphin inhibits the reaction [rubimaillin results in decreased expression of ABCB1 mrna]

https://ctdbase.org/detail.go?type=gene&acc=5243

BIMP017089

ABCB1

Homo sapiens (human)

Allyl sulfide results in increased expression of ABCB1 mRNA

https://ctdbase.org/detail.go?type=gene&acc=5243

BIMP017190

ABCB1

Homo sapiens (human)

Protoapigenone analog results in decreased expression of ABCB1 protein

https://ctdbase.org/detail.go?type=gene&acc=5243

BIMP017628

ABCB1

Homo sapiens (human)

4-cumylphenol results in increased expression of ABCB1 mRNA

https://ctdbase.org/detail.go?type=gene&acc=5243

BIMP013162

ABCB1

Homo sapiens (human)

Deoxyglucose inhibits the reaction [ABCB1 protein results in increased export of diazinon]

https://ctdbase.org/detail.go?type=gene&acc=5243

BIMP015925

ABCB1

Homo sapiens (human)

3-hydroxyflavone results in increased expression of ABCB1 mRNA

https://ctdbase.org/detail.go?type=gene&acc=5243

BIMP016143

ABCB1

Rattus norvegicus (Norway rat)

Toluene affects the expression of ABCB1 mRNA

https://ctdbase.org/detail.go?type=gene&acc=5243

BIMP011758

ABCB1

Homo sapiens (human)

Abietic acid inhibits the reaction [ABCB1 protein results in increased uptake of digoxin]

https://ctdbase.org/detail.go?type=gene&acc=5243

BIMP007782

ABCB1

Homo sapiens (human)

Cepharanthine results in decreased activity of ABCB1 protein

https://ctdbase.org/detail.go?type=gene&acc=5243

BIMP001962

ABCB1

Homo sapiens (human)

Glycyrrhetinic acid inhibits the reaction [ABCB1 protein results in increased uptake of digoxin]

https://ctdbase.org/detail.go?type=gene&acc=5243

BIMP001962

ABCB1

Homo sapiens (human)

Glycyrrhetinic acid inhibits the reaction [verapamil results in increased activity of ABCB1 protein]|[glycyrrhetinic acid affects the activity of ABCB1 protein] which results in increased abundance of daunorubicin|[glycyrrhetinic acid affects the activity of ABCB1 protein] which affects the susceptibility to vinblastine

https://ctdbase.org/detail.go?type=gene&acc=5243

BIMP011298

ABCB1

Homo sapiens (human)

Butyrates results in increased expression of ABCB1 mRNA

https://ctdbase.org/detail.go?type=gene&acc=5243

BIMP012327

ABCB1

Homo sapiens (human)

Flavone results in increased activity of ABCB1 protein|flavone promotes the reaction [elacridar inhibits the reaction [ABCB1 protein results in decreased uptake of daunorubicin]]|flavone results in decreased expression of ABCB1 protein|flavone inhibits the reaction [ABCB1 protein results in decreased uptake of rhodamine 123]|flavone inhibits the reaction [ABCB1 protein results in decreased uptake of daunorubicin]

https://ctdbase.org/detail.go?type=gene&acc=5243

BIMP016421

ABCB1

Homo sapiens (human)

Terpinolene inhibits the reaction [ABCB1 protein results in increased uptake of digoxin]

https://ctdbase.org/detail.go?type=gene&acc=5243