Molecular Targets : Dataset Browser

BIMP_ID	Target Name	Gene	Organism	Action	Source URL
BIMP019430	ABCB1	ABCB1	Rattus norvegicus (Norway rat)	Acetylcysteine inhibits the reaction [vehicle emissions results in increased expression of and results in increased activity of ABCB1 protein]\|acetylcysteine inhibits the reaction [particulate matter results in increased expression of and results in increased activity of ABCB1 protein]	https://ctdbase.org/detail.go?type=gene&acc=5243
BIMP018678	ABCB1	ABCB1	Homo sapiens (human)	[matairesinol affects the activity of ABCB1 protein] which results in increased abundance of daunorubicin	https://ctdbase.org/detail.go?type=gene&acc=5243
BIMP018689	ABCB1	ABCB1	Homo sapiens (human)	Dioscin results in decreased expression of ABCB1 protein\|dioscin results in decreased expression of ABCB1 mrna\|dioscin results in decreased expression of ABCB1	https://ctdbase.org/detail.go?type=gene&acc=5243
BIMP018751	ABCB1	ABCB1	Homo sapiens (human)		https://www.dgidb.org/genes/hgnc:40
BIMP019233	ABCB1	ABCB1	Homo sapiens (human)	Ginkgolide B results in increased expression of ABCB1 mRNA	https://ctdbase.org/detail.go?type=gene&acc=5243
BIMP019233	ABCB1	ABCB1	Homo sapiens (human)	Sulforaphane inhibits the reaction [ginkgolide B results in increased expression of ABCB1 mrna]\|nr1i2 protein affects the reaction [ginkgolide B results in increased expression of ABCB1 mrna]	https://ctdbase.org/detail.go?type=gene&acc=5243
BIMP026425	ABCB1	ABCB1	Homo sapiens (human)	ABCB1 protein results in increased hydrolysis of guanosine triphosphate	https://ctdbase.org/detail.go?type=gene&acc=5243
BIMP021255	ABCB1	ABCB1	Homo sapiens (human)	Cannogenin thevetoside inhibits the reaction [ABCB1 protein results in increased transport of quinidinium]	https://ctdbase.org/detail.go?type=gene&acc=5243
BIMP025809	ABCB1	ABCB1	Homo sapiens (human)	Verapamil inhibits the reaction [ABCB1 protein affects the uptake of vinblastine]\|abcb1 protein affects the uptake of vinblastine	https://ctdbase.org/detail.go?type=gene&acc=5243
BIMP025809	ABCB1	ABCB1	Homo sapiens (human)	ABCB1 protein results in decreased susceptibility to vinblastine	https://ctdbase.org/detail.go?type=gene&acc=5243
BIMP025809	ABCB1	ABCB1	Homo sapiens (human)	Clotrimazole inhibits the reaction [ABCB1 protein results in increased secretion of vinblastine]\|miconazole inhibits the reaction [ABCB1 protein results in increased secretion of vinblastine]\|troleandomycin inhibits the reaction [ABCB1 protein results in increased secretion of vinblastine]\|cyclosporine inhibits the reaction [ABCB1 protein results in increased secretion of vinblastine]\|erythromycin inhibits the reaction [ABCB1 protein results in increased secretion of vinblastine]\|abcb1 protein results in increased secretion of vinblastine\|reserpine inhibits the reaction [ABCB1 protein results in increased secretion of vinblastine]\|ketoconazole inhibits the reaction [ABCB1 protein results in increased secretion of vinblastine]\|amiodarone inhibits the reaction [ABCB1 protein results in increased secretion of vinblastine]	https://ctdbase.org/detail.go?type=gene&acc=5243
BIMP025809	ABCB1	ABCB1	Homo sapiens (human)	ABCB1 protein results in increased transport of vinblastine	https://ctdbase.org/detail.go?type=gene&acc=5243
BIMP025809	ABCB1	ABCB1	Homo sapiens (human)	Carvedilol inhibits the reaction [ABCB1 protein results in increased transport of vinblastine]\|[carvedilol inhibits the reaction [ABCB1 protein results in increased transport of vinblastine]] which results in decreased susceptibility to vinblastine\|verapamil inhibits the reaction [ABCB1 protein results in increased transport of vinblastine]	https://ctdbase.org/detail.go?type=gene&acc=5243
BIMP025809	ABCB1	ABCB1	Homo sapiens (human)	Cnidiadin inhibits the reaction [ABCB1 protein results in increased export of vinblastine]	https://ctdbase.org/detail.go?type=gene&acc=5243
BIMP025809	ABCB1	ABCB1	Homo sapiens (human)	Curcumin inhibits the reaction [ABCB1 protein results in decreased susceptibility to vinblastine]\|curcumin analog inhibits the reaction [ABCB1 protein results in decreased susceptibility to vinblastine]	https://ctdbase.org/detail.go?type=gene&acc=5243
BIMP025809	ABCB1	ABCB1	Homo sapiens (human)	Diazinon affects the reaction [ABCB1 protein results in increased transport of vinblastine]	https://ctdbase.org/detail.go?type=gene&acc=5243
BIMP025809	ABCB1	ABCB1	Homo sapiens (human)	Vinblastine binds to ABCB1 protein\|[elacridar binds to and results in decreased activity of ABCB1 protein] which results in decreased export of vinblastine	https://ctdbase.org/detail.go?type=gene&acc=5243
BIMP025809	ABCB1	ABCB1	Homo sapiens (human)	[glycyrrhetinic acid affects the activity of ABCB1 protein] which affects the susceptibility to vinblastine	https://ctdbase.org/detail.go?type=gene&acc=5243
BIMP025809	ABCB1	ABCB1	Homo sapiens (human)	Vinblastine results in increased expression of ABCB1 protein\|[vinblastine results in increased activity of NR1I2 protein] which results in increased expression of ABCB1 mrna\|nr1i2 protein promotes the reaction [vinblastine results in increased expression of ABCB1 protein]	https://ctdbase.org/detail.go?type=gene&acc=5243
BIMP025809	ABCB1	ABCB1	Homo sapiens (human)	Sesquiterpenes analog inhibits the reaction [ABCB1 protein results in decreased susceptibility to vinblastine]	https://ctdbase.org/detail.go?type=gene&acc=5243
BIMP025809	ABCB1	ABCB1	Homo sapiens (human)	[sodium arsenite results in increased expression of ABCB1 protein] which results in decreased susceptibility to vinblastine	https://ctdbase.org/detail.go?type=gene&acc=5243
BIMP025809	ABCB1	ABCB1	Homo sapiens (human)	Vinblastine inhibits the reaction [verapamil analog results in increased activity of ABCB1 protein mutant form]\|vinblastine results in increased activity of ABCB1 protein mutant form	https://ctdbase.org/detail.go?type=gene&acc=5243
BIMP025809	ABCB1	ABCB1	Oncorhynchus mykiss (rainbow trout)	Vinblastine results in decreased activity of ABCB1 protein	https://ctdbase.org/detail.go?type=gene&acc=5243
BIMP025809	ABCB1	ABCB1	Orbicella franksi	Vinblastine results in increased expression of ABCB1 mRNA	https://ctdbase.org/detail.go?type=gene&acc=5243
BIMP025809	ABCB1	ABCB1	Rattus norvegicus (Norway rat)	ABCB1 protein results in decreased susceptibility to vinblastine	https://ctdbase.org/detail.go?type=gene&acc=5243

BIMP019430

ABCB1

Rattus norvegicus (Norway rat)

Acetylcysteine inhibits the reaction [vehicle emissions results in increased expression of and results in increased activity of ABCB1 protein]|acetylcysteine inhibits the reaction [particulate matter results in increased expression of and results in increased activity of ABCB1 protein]

https://ctdbase.org/detail.go?type=gene&acc=5243

BIMP018678

ABCB1

Homo sapiens (human)

[matairesinol affects the activity of ABCB1 protein] which results in increased abundance of daunorubicin

https://ctdbase.org/detail.go?type=gene&acc=5243

BIMP018689

ABCB1

Homo sapiens (human)

Dioscin results in decreased expression of ABCB1 protein|dioscin results in decreased expression of ABCB1 mrna|dioscin results in decreased expression of ABCB1

https://ctdbase.org/detail.go?type=gene&acc=5243

BIMP018751

ABCB1

Homo sapiens (human)

https://www.dgidb.org/genes/hgnc:40

BIMP019233

ABCB1

Homo sapiens (human)

Ginkgolide B results in increased expression of ABCB1 mRNA

https://ctdbase.org/detail.go?type=gene&acc=5243

BIMP019233

ABCB1

Homo sapiens (human)

Sulforaphane inhibits the reaction [ginkgolide B results in increased expression of ABCB1 mrna]|nr1i2 protein affects the reaction [ginkgolide B results in increased expression of ABCB1 mrna]

https://ctdbase.org/detail.go?type=gene&acc=5243

BIMP026425

ABCB1

Homo sapiens (human)

ABCB1 protein results in increased hydrolysis of guanosine triphosphate

https://ctdbase.org/detail.go?type=gene&acc=5243

BIMP021255

ABCB1

Homo sapiens (human)

Cannogenin thevetoside inhibits the reaction [ABCB1 protein results in increased transport of quinidinium]

https://ctdbase.org/detail.go?type=gene&acc=5243

BIMP025809

ABCB1

Homo sapiens (human)

Verapamil inhibits the reaction [ABCB1 protein affects the uptake of vinblastine]|abcb1 protein affects the uptake of vinblastine

https://ctdbase.org/detail.go?type=gene&acc=5243

BIMP025809

ABCB1

Homo sapiens (human)

ABCB1 protein results in decreased susceptibility to vinblastine

https://ctdbase.org/detail.go?type=gene&acc=5243

BIMP025809

ABCB1

Homo sapiens (human)

Clotrimazole inhibits the reaction [ABCB1 protein results in increased secretion of vinblastine]|miconazole inhibits the reaction [ABCB1 protein results in increased secretion of vinblastine]|troleandomycin inhibits the reaction [ABCB1 protein results in increased secretion of vinblastine]|cyclosporine inhibits the reaction [ABCB1 protein results in increased secretion of vinblastine]|erythromycin inhibits the reaction [ABCB1 protein results in increased secretion of vinblastine]|abcb1 protein results in increased secretion of vinblastine|reserpine inhibits the reaction [ABCB1 protein results in increased secretion of vinblastine]|ketoconazole inhibits the reaction [ABCB1 protein results in increased secretion of vinblastine]|amiodarone inhibits the reaction [ABCB1 protein results in increased secretion of vinblastine]

https://ctdbase.org/detail.go?type=gene&acc=5243

BIMP025809

ABCB1

Homo sapiens (human)

ABCB1 protein results in increased transport of vinblastine

https://ctdbase.org/detail.go?type=gene&acc=5243

BIMP025809

ABCB1

Homo sapiens (human)

Carvedilol inhibits the reaction [ABCB1 protein results in increased transport of vinblastine]|[carvedilol inhibits the reaction [ABCB1 protein results in increased transport of vinblastine]] which results in decreased susceptibility to vinblastine|verapamil inhibits the reaction [ABCB1 protein results in increased transport of vinblastine]

https://ctdbase.org/detail.go?type=gene&acc=5243

BIMP025809

ABCB1

Homo sapiens (human)

Cnidiadin inhibits the reaction [ABCB1 protein results in increased export of vinblastine]

https://ctdbase.org/detail.go?type=gene&acc=5243

BIMP025809

ABCB1

Homo sapiens (human)

Curcumin inhibits the reaction [ABCB1 protein results in decreased susceptibility to vinblastine]|curcumin analog inhibits the reaction [ABCB1 protein results in decreased susceptibility to vinblastine]

https://ctdbase.org/detail.go?type=gene&acc=5243

BIMP025809

ABCB1

Homo sapiens (human)

Diazinon affects the reaction [ABCB1 protein results in increased transport of vinblastine]

https://ctdbase.org/detail.go?type=gene&acc=5243

BIMP025809

ABCB1

Homo sapiens (human)

Vinblastine binds to ABCB1 protein|[elacridar binds to and results in decreased activity of ABCB1 protein] which results in decreased export of vinblastine

https://ctdbase.org/detail.go?type=gene&acc=5243

BIMP025809

ABCB1

Homo sapiens (human)

[glycyrrhetinic acid affects the activity of ABCB1 protein] which affects the susceptibility to vinblastine

https://ctdbase.org/detail.go?type=gene&acc=5243

BIMP025809

ABCB1

Homo sapiens (human)

Vinblastine results in increased expression of ABCB1 protein|[vinblastine results in increased activity of NR1I2 protein] which results in increased expression of ABCB1 mrna|nr1i2 protein promotes the reaction [vinblastine results in increased expression of ABCB1 protein]

https://ctdbase.org/detail.go?type=gene&acc=5243

BIMP025809

ABCB1

Homo sapiens (human)

Sesquiterpenes analog inhibits the reaction [ABCB1 protein results in decreased susceptibility to vinblastine]

https://ctdbase.org/detail.go?type=gene&acc=5243

BIMP025809

ABCB1

Homo sapiens (human)

[sodium arsenite results in increased expression of ABCB1 protein] which results in decreased susceptibility to vinblastine

https://ctdbase.org/detail.go?type=gene&acc=5243

BIMP025809

ABCB1

Homo sapiens (human)

Vinblastine inhibits the reaction [verapamil analog results in increased activity of ABCB1 protein mutant form]|vinblastine results in increased activity of ABCB1 protein mutant form

https://ctdbase.org/detail.go?type=gene&acc=5243

BIMP025809

ABCB1

Oncorhynchus mykiss (rainbow trout)

Vinblastine results in decreased activity of ABCB1 protein

https://ctdbase.org/detail.go?type=gene&acc=5243

BIMP025809

ABCB1

Orbicella franksi

Vinblastine results in increased expression of ABCB1 mRNA

https://ctdbase.org/detail.go?type=gene&acc=5243

BIMP025809

ABCB1

Rattus norvegicus (Norway rat)

ABCB1 protein results in decreased susceptibility to vinblastine

https://ctdbase.org/detail.go?type=gene&acc=5243