Molecular Targets : Dataset Browser

BIMP_ID	Target Name	Gene	Organism	Action	Source URL
BIMP073133	ABCB1	ABCB1	Homo sapiens (human)	Gallic acid results in decreased expression of ABCB1 protein	https://ctdbase.org/detail.go?type=gene&acc=5243
BIMP073081	ABCB1	ABCB1	Canis lupus familiaris (dog)	Hypericin inhibits the reaction [ABCB1 protein results in increased secretion of ritonavir]	https://ctdbase.org/detail.go?type=gene&acc=5243
BIMP073081	ABCB1	ABCB1	Homo sapiens (human)	Hypericin results in increased expression of ABCB1	https://ctdbase.org/detail.go?type=gene&acc=5243
BIMP073107	ABCB1	ABCB1	Cyprinus carpio (common carp)	Ibuprofen results in increased expression of ABCB1 mRNA	https://ctdbase.org/detail.go?type=gene&acc=5243
BIMP073107	ABCB1	ABCB1	Dreissena polymorpha	Ibuprofen results in decreased expression of ABCB1 mRNA	https://ctdbase.org/detail.go?type=gene&acc=5243
BIMP073146	ABCB1	ABCB1	Homo sapiens (human)	Indole-3-carbinol results in decreased expression of ABCB1	https://ctdbase.org/detail.go?type=gene&acc=5243
BIMP073059	ABCB1	ABCB1	Homo sapiens (human)	ABCB1 exon polymorphism affects the susceptibility to etoposide	https://ctdbase.org/detail.go?type=gene&acc=5243
BIMP073059	ABCB1	ABCB1	Homo sapiens (human)	[celecoxib results in decreased expression of ABCB1] which results in increased susceptibility to etoposide	https://ctdbase.org/detail.go?type=gene&acc=5243
BIMP073059	ABCB1	ABCB1	Homo sapiens (human)	Etoposide results in increased expression of ABCB1 mRNA	https://ctdbase.org/detail.go?type=gene&acc=5243
BIMP073059	ABCB1	ABCB1	Homo sapiens (human)	Etoposide results in increased expression of ABCB1 protein	https://ctdbase.org/detail.go?type=gene&acc=5243
BIMP073059	ABCB1	ABCB1	Homo sapiens (human)	[[[[hyaluronic acid binds to CD44 protein] which results in increased expression of and results in increased activity of EP300 protein] which results in increased acetylation of and results in increased activity of CTNNB1 protein] which results in increased expression of ABCB1 protein] inhibits the reaction [etoposide results in increased activity of CASP3 protein]\|[[[[hyaluronic acid binds to CD44 protein] which results in increased expression of and results in increased activity of EP300 protein] which results in increased acetylation of and results in increased activity of RELA protein] which results in increased expression of ABCB1 protein] inhibits the reaction [etoposide results in increased activity of CASP3 protein]	https://ctdbase.org/detail.go?type=gene&acc=5243
BIMP073059	ABCB1	ABCB1	Homo sapiens (human)	[ABCB1 protein co-treated with MGMT protein mutant form] results in decreased susceptibility to etoposide\|verapamil inhibits the reaction [[ABCB1 protein co-treated with MGMT protein mutant form] results in decreased susceptibility to etoposide]	https://ctdbase.org/detail.go?type=gene&acc=5243
BIMP073132	ABCB1	ABCB1	Homo sapiens (human)	5,3'-dihydroxy-3,6,7,8,4'-pentamethoxyflavone inhibits the reaction [[ABCB1 protein results in decreased susceptibility to doxorubicin] promotes the reaction [tetradecanoylphorbol acetate results in increased expression of ABCB1 mrna]]	https://ctdbase.org/detail.go?type=gene&acc=5243
BIMP073132	ABCB1	ABCB1	Homo sapiens (human)	[ABCB1 protein results in decreased susceptibility to doxorubicin] affects the reaction [5,3'-dihydroxy-3,6,7,8,4'-pentamethoxyflavone inhibits the reaction [tetradecanoylphorbol acetate results in increased expression of VEGFA mrna]]	https://ctdbase.org/detail.go?type=gene&acc=5243
BIMP067850	ABCB1	ABCB1	Rattus norvegicus (Norway rat)	Acetovanillone inhibits the reaction [vehicle emissions results in increased expression of and results in increased activity of ABCB1 protein]\|acetovanillone inhibits the reaction [particulate matter results in increased expression of and results in increased activity of ABCB1 protein]	https://ctdbase.org/detail.go?type=gene&acc=5243
BIMP068008	ABCB1	ABCB1	Homo sapiens (human)	Aristolochic acid I results in decreased expression of ABCB1 mRNA	https://ctdbase.org/detail.go?type=gene&acc=5243
BIMP067942	ABCB1	ABCB1	Homo sapiens (human)	Deoxycholic acid metabolite results in increased expression of ABCB1 mRNA	https://ctdbase.org/detail.go?type=gene&acc=5243
BIMP067942	ABCB1	ABCB1	Homo sapiens (human)	[glycochenodeoxycholic acid co-treated with deoxycholic acid co-treated with chenodeoxycholic acid co-treated with glycodeoxycholic acid co-treated with glycocholic acid co-treated with tartrazine] results in decreased expression of ABCB1 mrna\|[glycochenodeoxycholic acid co-treated with deoxycholic acid co-treated with chenodeoxycholic acid co-treated with glycodeoxycholic acid co-treated with glycocholic acid co-treated with atazanavir sulfate] results in decreased expression of ABCB1 mRNA	https://ctdbase.org/detail.go?type=gene&acc=5243
BIMP068022	ABCB1	ABCB1	Homo sapiens (human)	Aspirin results in increased activity of ABCB1 protein	https://ctdbase.org/detail.go?type=gene&acc=5243
BIMP068022	ABCB1	ABCB1	Homo sapiens (human)	Aspirin results in increased expression of ABCB1 protein\|[aspirin results in increased expression of ABCB1 protein] which results in decreased uptake of clopidogrel\|aspirin results in increased expression of ABCB1 mRNA	https://ctdbase.org/detail.go?type=gene&acc=5243
BIMP068028	ABCB1	ABCB1	Homo sapiens (human)		https://www.dgidb.org/genes/hgnc:40
BIMP019430	ABCB1	ABCB1	Homo sapiens (human)	Acetylcysteine affects the reaction [[gambogic acid affects the reaction [ABCB1 protein affects the susceptibility to doxorubicin]] which affects the cleavage of PARP1 protein]\|acetylcysteine affects the reaction [[gambogic acid affects the reaction [ABCB1 protein affects the susceptibility to doxorubicin]] which affects the cleavage of CASP7 protein]	https://ctdbase.org/detail.go?type=gene&acc=5243
BIMP019430	ABCB1	ABCB1	Homo sapiens (human)	Acetylcysteine inhibits the reaction [3',4',7-trihydroxyisoflavone results in decreased expression of ABCB1 mrna]	https://ctdbase.org/detail.go?type=gene&acc=5243
BIMP019430	ABCB1	ABCB1	Homo sapiens (human)	Acetylcysteine inhibits the reaction [formononetin results in increased expression of ABCB1 mrna]	https://ctdbase.org/detail.go?type=gene&acc=5243
BIMP019430	ABCB1	ABCB1	Rattus norvegicus (Norway rat)	Acetylcysteine inhibits the reaction [cadmium chloride results in increased expression of ABCB1]	https://ctdbase.org/detail.go?type=gene&acc=5243

BIMP073133

ABCB1

Homo sapiens (human)

Gallic acid results in decreased expression of ABCB1 protein

https://ctdbase.org/detail.go?type=gene&acc=5243

BIMP073081

ABCB1

Canis lupus familiaris (dog)

Hypericin inhibits the reaction [ABCB1 protein results in increased secretion of ritonavir]

https://ctdbase.org/detail.go?type=gene&acc=5243

BIMP073081

ABCB1

Homo sapiens (human)

Hypericin results in increased expression of ABCB1

https://ctdbase.org/detail.go?type=gene&acc=5243

BIMP073107

ABCB1

Cyprinus carpio (common carp)

Ibuprofen results in increased expression of ABCB1 mRNA

https://ctdbase.org/detail.go?type=gene&acc=5243

BIMP073107

ABCB1

Dreissena polymorpha

Ibuprofen results in decreased expression of ABCB1 mRNA

https://ctdbase.org/detail.go?type=gene&acc=5243

BIMP073146

ABCB1

Homo sapiens (human)

Indole-3-carbinol results in decreased expression of ABCB1

https://ctdbase.org/detail.go?type=gene&acc=5243

BIMP073059

ABCB1

Homo sapiens (human)

ABCB1 exon polymorphism affects the susceptibility to etoposide

https://ctdbase.org/detail.go?type=gene&acc=5243

BIMP073059

ABCB1

Homo sapiens (human)

[celecoxib results in decreased expression of ABCB1] which results in increased susceptibility to etoposide

https://ctdbase.org/detail.go?type=gene&acc=5243

BIMP073059

ABCB1

Homo sapiens (human)

Etoposide results in increased expression of ABCB1 mRNA

https://ctdbase.org/detail.go?type=gene&acc=5243

BIMP073059

ABCB1

Homo sapiens (human)

Etoposide results in increased expression of ABCB1 protein

https://ctdbase.org/detail.go?type=gene&acc=5243

BIMP073059

ABCB1

Homo sapiens (human)

[[[[hyaluronic acid binds to CD44 protein] which results in increased expression of and results in increased activity of EP300 protein] which results in increased acetylation of and results in increased activity of CTNNB1 protein] which results in increased expression of ABCB1 protein] inhibits the reaction [etoposide results in increased activity of CASP3 protein]|[[[[hyaluronic acid binds to CD44 protein] which results in increased expression of and results in increased activity of EP300 protein] which results in increased acetylation of and results in increased activity of RELA protein] which results in increased expression of ABCB1 protein] inhibits the reaction [etoposide results in increased activity of CASP3 protein]

https://ctdbase.org/detail.go?type=gene&acc=5243

BIMP073059

ABCB1

Homo sapiens (human)

[ABCB1 protein co-treated with MGMT protein mutant form] results in decreased susceptibility to etoposide|verapamil inhibits the reaction [[ABCB1 protein co-treated with MGMT protein mutant form] results in decreased susceptibility to etoposide]

https://ctdbase.org/detail.go?type=gene&acc=5243

BIMP073132

ABCB1

Homo sapiens (human)

5,3'-dihydroxy-3,6,7,8,4'-pentamethoxyflavone inhibits the reaction [[ABCB1 protein results in decreased susceptibility to doxorubicin] promotes the reaction [tetradecanoylphorbol acetate results in increased expression of ABCB1 mrna]]

https://ctdbase.org/detail.go?type=gene&acc=5243

BIMP073132

ABCB1

Homo sapiens (human)

[ABCB1 protein results in decreased susceptibility to doxorubicin] affects the reaction [5,3'-dihydroxy-3,6,7,8,4'-pentamethoxyflavone inhibits the reaction [tetradecanoylphorbol acetate results in increased expression of VEGFA mrna]]

https://ctdbase.org/detail.go?type=gene&acc=5243

BIMP067850

ABCB1

Rattus norvegicus (Norway rat)

Acetovanillone inhibits the reaction [vehicle emissions results in increased expression of and results in increased activity of ABCB1 protein]|acetovanillone inhibits the reaction [particulate matter results in increased expression of and results in increased activity of ABCB1 protein]

https://ctdbase.org/detail.go?type=gene&acc=5243

BIMP068008

ABCB1

Homo sapiens (human)

Aristolochic acid I results in decreased expression of ABCB1 mRNA

https://ctdbase.org/detail.go?type=gene&acc=5243

BIMP067942

ABCB1

Homo sapiens (human)

Deoxycholic acid metabolite results in increased expression of ABCB1 mRNA

https://ctdbase.org/detail.go?type=gene&acc=5243

BIMP067942

ABCB1

Homo sapiens (human)

[glycochenodeoxycholic acid co-treated with deoxycholic acid co-treated with chenodeoxycholic acid co-treated with glycodeoxycholic acid co-treated with glycocholic acid co-treated with tartrazine] results in decreased expression of ABCB1 mrna|[glycochenodeoxycholic acid co-treated with deoxycholic acid co-treated with chenodeoxycholic acid co-treated with glycodeoxycholic acid co-treated with glycocholic acid co-treated with atazanavir sulfate] results in decreased expression of ABCB1 mRNA

https://ctdbase.org/detail.go?type=gene&acc=5243

BIMP068022

ABCB1

Homo sapiens (human)

Aspirin results in increased activity of ABCB1 protein

https://ctdbase.org/detail.go?type=gene&acc=5243

BIMP068022

ABCB1

Homo sapiens (human)

Aspirin results in increased expression of ABCB1 protein|[aspirin results in increased expression of ABCB1 protein] which results in decreased uptake of clopidogrel|aspirin results in increased expression of ABCB1 mRNA

https://ctdbase.org/detail.go?type=gene&acc=5243

BIMP068028

ABCB1

Homo sapiens (human)

https://www.dgidb.org/genes/hgnc:40

BIMP019430

ABCB1

Homo sapiens (human)

Acetylcysteine affects the reaction [[gambogic acid affects the reaction [ABCB1 protein affects the susceptibility to doxorubicin]] which affects the cleavage of PARP1 protein]|acetylcysteine affects the reaction [[gambogic acid affects the reaction [ABCB1 protein affects the susceptibility to doxorubicin]] which affects the cleavage of CASP7 protein]

https://ctdbase.org/detail.go?type=gene&acc=5243

BIMP019430

ABCB1

Homo sapiens (human)

Acetylcysteine inhibits the reaction [3',4',7-trihydroxyisoflavone results in decreased expression of ABCB1 mrna]

https://ctdbase.org/detail.go?type=gene&acc=5243

BIMP019430

ABCB1

Homo sapiens (human)

Acetylcysteine inhibits the reaction [formononetin results in increased expression of ABCB1 mrna]

https://ctdbase.org/detail.go?type=gene&acc=5243

BIMP019430

ABCB1

Rattus norvegicus (Norway rat)

Acetylcysteine inhibits the reaction [cadmium chloride results in increased expression of ABCB1]

https://ctdbase.org/detail.go?type=gene&acc=5243