Molecular Targets : Dataset Browser

BIMP_ID	Target Name	Gene	Organism	Action	Source URL
BIMP078706	ABCB1	ABCB1	Homo sapiens (human)	Nifedipine results in increased expression of ABCB1 protein	https://ctdbase.org/detail.go?type=gene&acc=5243
BIMP078706	ABCB1	ABCB1	Homo sapiens (human)		https://www.dgidb.org/genes/hgnc:40
BIMP077156	ABCB1	ABCB1	Rattus norvegicus (Norway rat)	Vitamin A results in decreased expression of ABCB1 mrna\|mannitol inhibits the reaction [vitamin A results in decreased expression of ABCB1 mrna]\|6-hydroxy-2,5,7,8-tetramethylchroman-2-carboxylic acid inhibits the reaction [vitamin A results in decreased expression of ABCB1 mrna]	https://ctdbase.org/detail.go?type=gene&acc=5243
BIMP079181	ABCB1	ABCB1	Homo sapiens (human)	N-(2-cyclohexyloxy-4-nitrophenyl)methanesulfonamide results in decreased expression of ABCB1 mRNA	https://ctdbase.org/detail.go?type=gene&acc=5243
BIMP079181	ABCB1	ABCB1	Homo sapiens (human)	N-(2-cyclohexyloxy-4-nitrophenyl)methanesulfonamide results in decreased expression of ABCB1 protein	https://ctdbase.org/detail.go?type=gene&acc=5243
BIMP079181	ABCB1	ABCB1	Homo sapiens (human)	N-(2-cyclohexyloxy-4-nitrophenyl)methanesulfonamide results in increased expression of ABCB1 mRNA	https://ctdbase.org/detail.go?type=gene&acc=5243
BIMP078712	ABCB1	ABCB1	Homo sapiens (human)	Diethylstilbestrol results in decreased expression of ABCB1 protein	https://ctdbase.org/detail.go?type=gene&acc=5243
BIMP078749	ABCB1	ABCB1	Homo sapiens (human)	Elacridar inhibits the reaction [ABCB1 protein results in increased transport of huperzine a]\|verapamil inhibits the reaction [ABCB1 protein results in increased transport of huperzine A]\|ABCB1 protein results in increased transport of huperzine A	https://ctdbase.org/detail.go?type=gene&acc=5243
BIMP078764	ABCB1	ABCB1	Homo sapiens (human)		https://www.dgidb.org/genes/hgnc:40
BIMP079116	ABCB1	ABCB1	Homo sapiens (human)	ABCB1 exon SNP affects the susceptibility to nortriptyline	https://ctdbase.org/detail.go?type=gene&acc=5243
BIMP072904	ABCB1	ABCB1	Homo sapiens (human)	Zidovudine results in increased expression of ABCB1 mRNA	https://ctdbase.org/detail.go?type=gene&acc=5243
BIMP072904	ABCB1	ABCB1	Homo sapiens (human)	Zidovudine results in increased expression of ABCB1 protein	https://ctdbase.org/detail.go?type=gene&acc=5243
BIMP072841	ABCB1	ABCB1	Homo sapiens (human)	[[chlorpyrifos co-treated with decamethrin co-treated with polymarcine co-treated with glyphosate] results in decreased susceptibility to fluorouracil] which results in increased expression of ABCB1 mrna\|[[chlorpyrifos co-treated with decamethrin co-treated with polymarcine co-treated with glyphosate] results in decreased susceptibility to cisplatin] which results in increased expression of ABCB1 protein\|[[chlorpyrifos co-treated with decamethrin co-treated with polymarcine co-treated with glyphosate] results in decreased susceptibility to temozolomide] which results in increased expression of ABCB1 mrna\|[[chlorpyrifos co-treated with decamethrin co-treated with polymarcine co-treated with glyphosate] results in decreased susceptibility to fluorouracil] which results in increased expression of ABCB1 protein\|[[chlorpyrifos co-treated with decamethrin co-treated with polymarcine co-treated with glyphosate] results in decreased susceptibility to temozolomide] which results in increased expression of ABCB1 protein\|[[chlorpyrifos co-treated with decamethrin co-treated with polymarcine co-treated with glyphosate] results in decreased susceptibility to cisplatin] which results in increased expression of ABCB1 mRNA	https://ctdbase.org/detail.go?type=gene&acc=5243
BIMP072904	ABCB1	ABCB1	Homo sapiens (human)		https://www.dgidb.org/genes/hgnc:40
BIMP072986	ABCB1	ABCB1	Homo sapiens (human)		https://www.dgidb.org/genes/hgnc:40
BIMP072986	ABCB1	ABCB1	Homo sapiens (human)	ABCB1 protein results in decreased susceptibility to miltefosine\|miltefosine binds to and results in decreased activity of ABCB1 protein	https://ctdbase.org/detail.go?type=gene&acc=5243
BIMP072653	ABCB1	ABCB1	Homo sapiens (human)	ABCB1 gene SNP affects the susceptibility to [cisplatin co-treated with fluorouracil]	https://ctdbase.org/detail.go?type=gene&acc=5243
BIMP072653	ABCB1	ABCB1	Homo sapiens (human)	ABCB1 protein affects the susceptibility to [fluorouracil co-treated with epirubicin co-treated with cyclophosphamide]\|abcb1 protein affects the susceptibility to [cyclophosphamide co-treated with methotrexate co-treated with fluorouracil]	https://ctdbase.org/detail.go?type=gene&acc=5243
BIMP072653	ABCB1	ABCB1	Homo sapiens (human)	[[chlorpyrifos co-treated with decamethrin co-treated with polymarcine co-treated with glyphosate] results in decreased susceptibility to fluorouracil] which results in increased expression of ABCB1 protein\|[[chlorpyrifos co-treated with decamethrin co-treated with polymarcine co-treated with glyphosate] results in decreased susceptibility to fluorouracil] which results in increased expression of ABCB1 mRNA	https://ctdbase.org/detail.go?type=gene&acc=5243
BIMP072653	ABCB1	ABCB1	Homo sapiens (human)	Fluorouracil results in decreased expression of ABCB1 mRNA	https://ctdbase.org/detail.go?type=gene&acc=5243
BIMP072653	ABCB1	ABCB1	Homo sapiens (human)	Fluorouracil results in increased expression of ABCB1 protein	https://ctdbase.org/detail.go?type=gene&acc=5243
BIMP072653	ABCB1	ABCB1	Homo sapiens (human)	[paclitaxel results in increased expression of ABCB1] which results in decreased susceptibility to fluorouracil	https://ctdbase.org/detail.go?type=gene&acc=5243
BIMP072653	ABCB1	ABCB1	Homo sapiens (human)		https://www.dgidb.org/genes/hgnc:40
BIMP072749	ABCB1	ABCB1	Homo sapiens (human)	Gambogic acid affects the reaction [ABCB1 protein affects the susceptibility to doxorubicin]\|acetylcysteine affects the reaction [[gambogic acid affects the reaction [ABCB1 protein affects the susceptibility to doxorubicin]] which affects the cleavage of PARP1 protein]\|[gambogic acid affects the reaction [ABCB1 protein affects the susceptibility to doxorubicin]] which affects the cleavage of CASP7 protein\|acetylcysteine affects the reaction [[gambogic acid affects the reaction [ABCB1 protein affects the susceptibility to doxorubicin]] which affects the cleavage of CASP7 protein]\|[gambogic acid affects the reaction [ABCB1 protein affects the susceptibility to doxorubicin]] which affects the cleavage of PARP1 protein	https://ctdbase.org/detail.go?type=gene&acc=5243
BIMP072777	ABCB1	ABCB1	Rattus norvegicus (Norway rat)	Gentamicins results in decreased expression of ABCB1 mRNA	https://ctdbase.org/detail.go?type=gene&acc=5243

BIMP078706

ABCB1

Homo sapiens (human)

Nifedipine results in increased expression of ABCB1 protein

https://ctdbase.org/detail.go?type=gene&acc=5243

BIMP078706

ABCB1

Homo sapiens (human)

https://www.dgidb.org/genes/hgnc:40

BIMP077156

ABCB1

Rattus norvegicus (Norway rat)

Vitamin A results in decreased expression of ABCB1 mrna|mannitol inhibits the reaction [vitamin A results in decreased expression of ABCB1 mrna]|6-hydroxy-2,5,7,8-tetramethylchroman-2-carboxylic acid inhibits the reaction [vitamin A results in decreased expression of ABCB1 mrna]

https://ctdbase.org/detail.go?type=gene&acc=5243

BIMP079181

ABCB1

Homo sapiens (human)

N-(2-cyclohexyloxy-4-nitrophenyl)methanesulfonamide results in decreased expression of ABCB1 mRNA

https://ctdbase.org/detail.go?type=gene&acc=5243

BIMP079181

ABCB1

Homo sapiens (human)

N-(2-cyclohexyloxy-4-nitrophenyl)methanesulfonamide results in decreased expression of ABCB1 protein

https://ctdbase.org/detail.go?type=gene&acc=5243

BIMP079181

ABCB1

Homo sapiens (human)

N-(2-cyclohexyloxy-4-nitrophenyl)methanesulfonamide results in increased expression of ABCB1 mRNA

https://ctdbase.org/detail.go?type=gene&acc=5243

BIMP078712

ABCB1

Homo sapiens (human)

Diethylstilbestrol results in decreased expression of ABCB1 protein

https://ctdbase.org/detail.go?type=gene&acc=5243

BIMP078749

ABCB1

Homo sapiens (human)

Elacridar inhibits the reaction [ABCB1 protein results in increased transport of huperzine a]|verapamil inhibits the reaction [ABCB1 protein results in increased transport of huperzine A]|ABCB1 protein results in increased transport of huperzine A

https://ctdbase.org/detail.go?type=gene&acc=5243

BIMP078764

ABCB1

Homo sapiens (human)

https://www.dgidb.org/genes/hgnc:40

BIMP079116

ABCB1

Homo sapiens (human)

ABCB1 exon SNP affects the susceptibility to nortriptyline

https://ctdbase.org/detail.go?type=gene&acc=5243

BIMP072904

ABCB1

Homo sapiens (human)

Zidovudine results in increased expression of ABCB1 mRNA

https://ctdbase.org/detail.go?type=gene&acc=5243

BIMP072904

ABCB1

Homo sapiens (human)

Zidovudine results in increased expression of ABCB1 protein

https://ctdbase.org/detail.go?type=gene&acc=5243

BIMP072841

ABCB1

Homo sapiens (human)

[[chlorpyrifos co-treated with decamethrin co-treated with polymarcine co-treated with glyphosate] results in decreased susceptibility to fluorouracil] which results in increased expression of ABCB1 mrna|[[chlorpyrifos co-treated with decamethrin co-treated with polymarcine co-treated with glyphosate] results in decreased susceptibility to cisplatin] which results in increased expression of ABCB1 protein|[[chlorpyrifos co-treated with decamethrin co-treated with polymarcine co-treated with glyphosate] results in decreased susceptibility to temozolomide] which results in increased expression of ABCB1 mrna|[[chlorpyrifos co-treated with decamethrin co-treated with polymarcine co-treated with glyphosate] results in decreased susceptibility to fluorouracil] which results in increased expression of ABCB1 protein|[[chlorpyrifos co-treated with decamethrin co-treated with polymarcine co-treated with glyphosate] results in decreased susceptibility to temozolomide] which results in increased expression of ABCB1 protein|[[chlorpyrifos co-treated with decamethrin co-treated with polymarcine co-treated with glyphosate] results in decreased susceptibility to cisplatin] which results in increased expression of ABCB1 mRNA

https://ctdbase.org/detail.go?type=gene&acc=5243

BIMP072904

ABCB1

Homo sapiens (human)

https://www.dgidb.org/genes/hgnc:40

BIMP072986

ABCB1

Homo sapiens (human)

https://www.dgidb.org/genes/hgnc:40

BIMP072986

ABCB1

Homo sapiens (human)

ABCB1 protein results in decreased susceptibility to miltefosine|miltefosine binds to and results in decreased activity of ABCB1 protein

https://ctdbase.org/detail.go?type=gene&acc=5243

BIMP072653

ABCB1

Homo sapiens (human)

ABCB1 gene SNP affects the susceptibility to [cisplatin co-treated with fluorouracil]

https://ctdbase.org/detail.go?type=gene&acc=5243

BIMP072653

ABCB1

Homo sapiens (human)

ABCB1 protein affects the susceptibility to [fluorouracil co-treated with epirubicin co-treated with cyclophosphamide]|abcb1 protein affects the susceptibility to [cyclophosphamide co-treated with methotrexate co-treated with fluorouracil]

https://ctdbase.org/detail.go?type=gene&acc=5243

BIMP072653

ABCB1

Homo sapiens (human)

[[chlorpyrifos co-treated with decamethrin co-treated with polymarcine co-treated with glyphosate] results in decreased susceptibility to fluorouracil] which results in increased expression of ABCB1 protein|[[chlorpyrifos co-treated with decamethrin co-treated with polymarcine co-treated with glyphosate] results in decreased susceptibility to fluorouracil] which results in increased expression of ABCB1 mRNA

https://ctdbase.org/detail.go?type=gene&acc=5243

BIMP072653

ABCB1

Homo sapiens (human)

Fluorouracil results in decreased expression of ABCB1 mRNA

https://ctdbase.org/detail.go?type=gene&acc=5243

BIMP072653

ABCB1

Homo sapiens (human)

Fluorouracil results in increased expression of ABCB1 protein

https://ctdbase.org/detail.go?type=gene&acc=5243

BIMP072653

ABCB1

Homo sapiens (human)

[paclitaxel results in increased expression of ABCB1] which results in decreased susceptibility to fluorouracil

https://ctdbase.org/detail.go?type=gene&acc=5243

BIMP072653

ABCB1

Homo sapiens (human)

https://www.dgidb.org/genes/hgnc:40

BIMP072749

ABCB1

Homo sapiens (human)

Gambogic acid affects the reaction [ABCB1 protein affects the susceptibility to doxorubicin]|acetylcysteine affects the reaction [[gambogic acid affects the reaction [ABCB1 protein affects the susceptibility to doxorubicin]] which affects the cleavage of PARP1 protein]|[gambogic acid affects the reaction [ABCB1 protein affects the susceptibility to doxorubicin]] which affects the cleavage of CASP7 protein|acetylcysteine affects the reaction [[gambogic acid affects the reaction [ABCB1 protein affects the susceptibility to doxorubicin]] which affects the cleavage of CASP7 protein]|[gambogic acid affects the reaction [ABCB1 protein affects the susceptibility to doxorubicin]] which affects the cleavage of PARP1 protein

https://ctdbase.org/detail.go?type=gene&acc=5243

BIMP072777

ABCB1

Rattus norvegicus (Norway rat)

Gentamicins results in decreased expression of ABCB1 mRNA

https://ctdbase.org/detail.go?type=gene&acc=5243