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Interactions between compounds and specific gene/protein targets.
| BIMP_ID | Target Name | Gene | Organism | Action | Source URL |
|---|---|---|---|---|---|
|
ABCB1
|
Homo sapiens (human)
|
4-methoxyamphetamine results in decreased activity of ABCB1 protein
|
https://ctdbase.org/detail.go?type=gene&acc=5243
|
||
|
ABCB1
|
Homo sapiens (human)
|
[resveratrol co-treated with doxorubicin] results in decreased expression of ABCB1 mrna|[[resveratrol co-treated with doxorubicin] results in decreased expression of ABCB1 mrna] which results in increased uptake of doxorubicin
|
https://ctdbase.org/detail.go?type=gene&acc=5243
|
||
|
ABCB1
|
Homo sapiens (human)
|
[resveratrol results in increased susceptibility to doxorubicin] which results in decreased expression of ABCB1 protein|[resveratrol results in increased susceptibility to doxorubicin] which results in decreased expression of ABCB1 mRNA
|
https://ctdbase.org/detail.go?type=gene&acc=5243
|
||
|
ABCB1
|
Homo sapiens (human)
|
[rifampin binds to and results in increased activity of NR1I2 protein] promotes the reaction [ABCB1 protein results in decreased uptake of doxorubicin]
|
https://ctdbase.org/detail.go?type=gene&acc=5243
|
||
|
ABCB1
|
Homo sapiens (human)
|
Terameprocol inhibits the reaction [doxorubicin results in increased expression of ABCB1 mrna]
|
https://ctdbase.org/detail.go?type=gene&acc=5243
|
||
|
ABCB1
|
Rattus norvegicus (Norway rat)
|
Tamoxifen inhibits the reaction [doxorubicin affects the activity of ABCB1 protein]|tamoxifen affects the reaction [ABCB1 protein results in increased secretion of doxorubicin]|abcb1 protein results in increased secretion of doxorubicin|doxorubicin affects the activity of ABCB1 protein
|
https://ctdbase.org/detail.go?type=gene&acc=5243
|
||
|
ABCB1
|
Rattus norvegicus (Norway rat)
|
Doxorubicin results in increased expression of ABCB1 mRNA
|
https://ctdbase.org/detail.go?type=gene&acc=5243
|
||
|
ABCB1
|
Homo sapiens (human)
|
ABCB1 protein results in decreased susceptibility to doxorubicin
|
https://ctdbase.org/detail.go?type=gene&acc=5243
|
||
|
ABCB1
|
Homo sapiens (human)
|
ABCB1 results in decreased susceptibility to doxorubicin
|
https://ctdbase.org/detail.go?type=gene&acc=5243
|
||
|
ABCB1
|
Homo sapiens (human)
|
Ursodeoxycholic acid results in increased expression of ABCB1 mRNA
|
https://ctdbase.org/detail.go?type=gene&acc=5243
|
||
|
ABCB1
|
Homo sapiens (human)
|
7-hydroxymitragynine results in decreased activity of ABCB1 protein
|
https://ctdbase.org/detail.go?type=gene&acc=5243
|
||
|
ABCB1
|
Homo sapiens (human)
|
|
https://www.dgidb.org/genes/hgnc:40
|
||
|
ABCB1
|
Homo sapiens (human)
|
[lipopolysaccharides co-treated with resveratrol] results in decreased expression of ABCB1 mRNA
|
https://ctdbase.org/detail.go?type=gene&acc=5243
|
||
|
ABCB1
|
Homo sapiens (human)
|
[methoxy poly(ethylene glycol-co-epsilon-caprolactone) co-treated with tocophersolan co-treated with resveratrol] results in decreased expression of ABCB1 protein
|
https://ctdbase.org/detail.go?type=gene&acc=5243
|
||
|
ABCB1
|
Homo sapiens (human)
|
[resveratrol co-treated with doxorubicin] results in decreased expression of ABCB1 mrna|[[resveratrol co-treated with doxorubicin] results in decreased expression of ABCB1 mrna] which results in increased uptake of doxorubicin
|
https://ctdbase.org/detail.go?type=gene&acc=5243
|
||
|
ABCB1
|
Homo sapiens (human)
|
Resveratrol inhibits the reaction [[[[hyaluronic acid binds to CD44 protein] which results in increased expression of and results in increased activity of EP300 protein] which results in increased acetylation of and results in increased activity of RELA protein] which results in increased expression of ABCB1 mrna]|resveratrol inhibits the reaction [[[[hyaluronic acid binds to CD44 protein] which results in increased expression of and results in increased activity of EP300 protein] which results in increased acetylation of and results in increased activity of CTNNB1 protein] which results in increased expression of ABCB1 protein]|resveratrol inhibits the reaction [[[[hyaluronic acid binds to CD44 protein] which results in increased expression of and results in increased activity of EP300 protein] which results in increased acetylation of and results in increased activity of CTNNB1 protein] which results in increased expression of ABCB1 mrna]|resveratrol inhibits the reaction [[[[hyaluronic acid binds to CD44 protein] which results in increased expression of and results in increased activity of EP300 protein] which results in increased acetylation of and results in increased activity of RELA protein] which results in increased expression of ABCB1 protein]
|
https://ctdbase.org/detail.go?type=gene&acc=5243
|
||
|
ABCB1
|
Homo sapiens (human)
|
Resveratrol inhibits the reaction [rifampin results in increased expression of ABCB1 protein]|resveratrol results in decreased expression of ABCB1 protein|resveratrol results in decreased expression of ABCB1 mRNA
|
https://ctdbase.org/detail.go?type=gene&acc=5243
|
||
|
ABCB1
|
Homo sapiens (human)
|
Resveratrol results in decreased expression of ABCB1
|
https://ctdbase.org/detail.go?type=gene&acc=5243
|
||
|
ABCB1
|
Homo sapiens (human)
|
Resveratrol results in decreased expression of ABCB1 mRNA
|
https://ctdbase.org/detail.go?type=gene&acc=5243
|
||
|
ABCB1
|
Homo sapiens (human)
|
Resveratrol results in increased expression of ABCB1 protein|resveratrol results in increased expression of ABCB1 mRNA
|
https://ctdbase.org/detail.go?type=gene&acc=5243
|
||
|
ABCB1
|
Homo sapiens (human)
|
[resveratrol results in increased susceptibility to doxorubicin] which results in decreased expression of ABCB1 protein|[resveratrol results in increased susceptibility to doxorubicin] which results in decreased expression of ABCB1 mRNA
|
https://ctdbase.org/detail.go?type=gene&acc=5243
|
||
|
ABCB1
|
Homo sapiens (human)
|
Resveratrol inhibits the reaction [ABCB1 protein results in increased transport of methotrexate]
|
https://ctdbase.org/detail.go?type=gene&acc=5243
|
||
|
ABCB1
|
Homo sapiens (human)
|
|
https://www.dgidb.org/genes/hgnc:40
|
||
|
ABCB1
|
Mus musculus (house mouse)
|
Geranylgeranyl pyrophosphate inhibits the reaction [kuwanon G results in increased expression of ABCB1 protein]
|
https://ctdbase.org/detail.go?type=gene&acc=5243
|
||
|
ABCB1
|
Homo sapiens (human)
|
|
https://www.dgidb.org/genes/hgnc:40
|
No matching records found on this page.