Molecular Targets : Dataset Browser

BIMP_ID	Target Name	Gene	Organism	Action	Source URL
BIMP071712	ABCB1	ABCB1	Homo sapiens (human)	Mitotane inhibits the reaction [ABCB1 protein results in increased export of daunorubicin]\|valspodar inhibits the reaction [ABCB1 protein results in increased export of daunorubicin]	https://ctdbase.org/detail.go?type=gene&acc=5243
BIMP071712	ABCB1	ABCB1	Homo sapiens (human)	[zosuquidar trihydrochloride results in decreased activity of ABCB1 protein] which results in decreased export of daunorubicin\|[mln 8237 affects the activity of ABCB1 protein] which affects the export of daunorubicin	https://ctdbase.org/detail.go?type=gene&acc=5243
BIMP071712	ABCB1	ABCB1	Homo sapiens (human)	Sesquiterpenes analog inhibits the reaction [ABCB1 protein results in decreased susceptibility to daunorubicin]	https://ctdbase.org/detail.go?type=gene&acc=5243
BIMP071712	ABCB1	ABCB1	Ovis aries (sheep)	ABCB1 results in decreased susceptibility to daunorubicin	https://ctdbase.org/detail.go?type=gene&acc=5243
BIMP071712	ABCB1	ABCB1	Homo sapiens (human)	Dabrafenib inhibits the reaction [ABCB1 protein results in decreased susceptibility to daunorubicin]\|abcb1 protein results in decreased susceptibility to daunorubicin	https://ctdbase.org/detail.go?type=gene&acc=5243
BIMP071712	ABCB1	ABCB1	Homo sapiens (human)	Mometasone furoate inhibits the reaction [ABCB1 results in decreased susceptibility to daunorubicin]\|abcb1 results in decreased susceptibility to daunorubicin	https://ctdbase.org/detail.go?type=gene&acc=5243
BIMP072300	ABCB1	ABCB1	Bos taurus (cattle)	[valspodar results in decreased activity of ABCB1 protein] promotes the reaction [doxorubicin results in decreased secretion of hydrocortisone]	https://ctdbase.org/detail.go?type=gene&acc=5243
BIMP072300	ABCB1	ABCB1	Canis lupus familiaris (dog)	ABCB1 protein affects the susceptibility to doxorubicin\|valspodar inhibits the reaction [ABCB1 protein affects the susceptibility to doxorubicin]	https://ctdbase.org/detail.go?type=gene&acc=5243
BIMP072300	ABCB1	ABCB1	Canis lupus familiaris (dog)	Doxorubicin results in increased expression of ABCB1 protein	https://ctdbase.org/detail.go?type=gene&acc=5243
BIMP072300	ABCB1	ABCB1	Canis lupus familiaris (dog)	Valspodar inhibits the reaction [ABCB1 protein results in decreased susceptibility to doxorubicin]	https://ctdbase.org/detail.go?type=gene&acc=5243
BIMP072300	ABCB1	ABCB1	Homo sapiens (human)	[2-(1-hydroxy-4-oxocyclohexa-2,5-dienyl)pyran-4-one results in increased susceptibility to doxorubicin] which results in decreased expression of ABCB1 protein	https://ctdbase.org/detail.go?type=gene&acc=5243
BIMP072300	ABCB1	ABCB1	Homo sapiens (human)	Kaempferol inhibits the reaction [[ABCB1 protein results in decreased susceptibility to doxorubicin] promotes the reaction [tetradecanoylphorbol acetate results in increased expression of ABCB1 mrna]]\|eriodictyol inhibits the reaction [[ABCB1 protein results in decreased susceptibility to doxorubicin] promotes the reaction [tetradecanoylphorbol acetate results in increased expression of ABCB1 mrna]]\|5,3'-dihydroxy-3,6,7,8,4'-pentamethoxyflavone inhibits the reaction [[ABCB1 protein results in decreased susceptibility to doxorubicin] promotes the reaction [tetradecanoylphorbol acetate results in increased expression of ABCB1 mrna]]\|withaferin A inhibits the reaction [[ABCB1 protein results in decreased susceptibility to doxorubicin] promotes the reaction [tetradecanoylphorbol acetate results in increased expression of ABCB1 mrna]]\|quercetin inhibits the reaction [[ABCB1 protein results in decreased susceptibility to doxorubicin] promotes the reaction [tetradecanoylphorbol acetate results in increased expression of ABCB1 mrna]]\|[abcb1 protein results in decreased susceptibility to doxorubicin] promotes the reaction [tetradecanoylphorbol acetate results in increased expression of ABCB1 mrna]	https://ctdbase.org/detail.go?type=gene&acc=5243
BIMP072300	ABCB1	ABCB1	Homo sapiens (human)	ABCB1 affects the susceptibility to doxorubicin	https://ctdbase.org/detail.go?type=gene&acc=5243
BIMP072300	ABCB1	ABCB1	Homo sapiens (human)	ABCB1 mRNA results in decreased susceptibility to doxorubicin	https://ctdbase.org/detail.go?type=gene&acc=5243
BIMP072300	ABCB1	ABCB1	Homo sapiens (human)	ABCB1 mRNA results in increased susceptibility to doxorubicin	https://ctdbase.org/detail.go?type=gene&acc=5243
BIMP072300	ABCB1	ABCB1	Homo sapiens (human)	ABCB1 protein affects the reaction [doxorubicin results in decreased susceptibility to paraquat]\|[doxorubicin results in increased expression of ABCB1 protein] which results in decreased susceptibility to paraquat	https://ctdbase.org/detail.go?type=gene&acc=5243
BIMP072300	ABCB1	ABCB1	Homo sapiens (human)	ABCB1 protein affects the susceptibility to doxorubicin	https://ctdbase.org/detail.go?type=gene&acc=5243
BIMP072300	ABCB1	ABCB1	Homo sapiens (human)	ABCB1 protein affects the transport of doxorubicin	https://ctdbase.org/detail.go?type=gene&acc=5243
BIMP072300	ABCB1	ABCB1	Homo sapiens (human)	Germacrone inhibits the reaction [doxorubicin results in increased expression of ABCB1 mrna]\|germacrone inhibits the reaction [doxorubicin results in increased expression of ABCB1 protein]\|abcb1 protein inhibits the reaction [germacrone results in increased susceptibility to doxorubicin]	https://ctdbase.org/detail.go?type=gene&acc=5243
BIMP072300	ABCB1	ABCB1	Homo sapiens (human)	ABCB1 protein inhibits the reaction [ursolic acid results in increased susceptibility to doxorubicin]	https://ctdbase.org/detail.go?type=gene&acc=5243
BIMP072300	ABCB1	ABCB1	Homo sapiens (human)	[verapamil results in decreased expression of ABCB1] promotes the reaction [doxorubicin results in increased activity of CASP3 protein]\|abcb1 protein results in decreased abundance of doxorubicin\|[verapamil results in decreased expression of ABCB1] promotes the reaction [doxorubicin results in increased activity of CASP7 protein]	https://ctdbase.org/detail.go?type=gene&acc=5243
BIMP072300	ABCB1	ABCB1	Homo sapiens (human)	ABCB1 protein results in decreased export of doxorubicin\|risperidone inhibits the reaction [ABCB1 protein results in decreased export of doxorubicin]\|paliperidone palmitate inhibits the reaction [ABCB1 protein results in decreased export of doxorubicin]	https://ctdbase.org/detail.go?type=gene&acc=5243
BIMP072300	ABCB1	ABCB1	Homo sapiens (human)	ABCB1 protein results in decreased secretion of doxorubicin\|cjx1, amlodipine derivative inhibits the reaction [ABCB1 protein results in decreased secretion of doxorubicin]	https://ctdbase.org/detail.go?type=gene&acc=5243
BIMP072300	ABCB1	ABCB1	Homo sapiens (human)	ABCB1 protein results in decreased susceptibility to doxorubicin	https://ctdbase.org/detail.go?type=gene&acc=5243
BIMP072300	ABCB1	ABCB1	Homo sapiens (human)	[ABCB1 protein results in decreased susceptibility to doxorubicin] affects the reaction [5,3'-dihydroxy-3,6,7,8,4'-pentamethoxyflavone inhibits the reaction [tetradecanoylphorbol acetate results in increased expression of VEGFA mrna]]\|[abcb1 protein results in decreased susceptibility to doxorubicin] inhibits the reaction [quercetin results in increased cleavage of PARP1 protein]\|[abcb1 protein results in decreased susceptibility to doxorubicin] affects the reaction [eriodictyol inhibits the reaction [tetradecanoylphorbol acetate results in increased expression of VEGFA mrna]]	https://ctdbase.org/detail.go?type=gene&acc=5243

BIMP071712

ABCB1

Homo sapiens (human)

Mitotane inhibits the reaction [ABCB1 protein results in increased export of daunorubicin]|valspodar inhibits the reaction [ABCB1 protein results in increased export of daunorubicin]