SCFBio, IIT Delhi
Hauz Khas, New Delhi
BIMP
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SCFBio, IIT Delhi
Interactions between compounds and specific gene/protein targets.
| BIMP_ID | Target Name | Gene | Organism | Action | Source URL |
|---|---|---|---|---|---|
|
ABCB1
|
Homo sapiens (human)
|
Clotrimazole results in increased expression of ABCB1 protein
|
https://ctdbase.org/detail.go?type=gene&acc=5243
|
||
|
ABCB1
|
Rattus norvegicus (Norway rat)
|
Clofibrate results in decreased expression of ABCB1 mRNA
|
https://ctdbase.org/detail.go?type=gene&acc=5243
|
||
|
ABCB1
|
Homo sapiens (human)
|
|
https://www.dgidb.org/genes/hgnc:40
|
||
|
ABCB1
|
Homo sapiens (human)
|
Mitragynine results in decreased activity of ABCB1 protein
|
https://ctdbase.org/detail.go?type=gene&acc=5243
|
||
|
ABCB1
|
Homo sapiens (human)
|
ABCB1 protein affects the uptake of quinine analog
|
https://ctdbase.org/detail.go?type=gene&acc=5243
|
||
|
ABCB1
|
Homo sapiens (human)
|
|
https://www.dgidb.org/genes/hgnc:40
|
||
|
ABCB1
|
Homo sapiens (human)
|
4-methyl-N1-(3-phenylpropyl)benzene-1,2-diamine inhibits the reaction [daunorubicin results in increased expression of ABCB1 mrna]|[imatinib mesylate inhibits the reaction [daunorubicin results in increased expression of ABCB1 protein]] which results in decreased export of daunorubicin|daunorubicin results in increased expression of ABCB1 mrna|daunorubicin results in increased expression of ABCB1 protein|imatinib mesylate inhibits the reaction [daunorubicin results in increased expression of ABCB1 protein]|4-(4-fluorophenyl)-2-(4-hydroxyphenyl)-5-(4-pyridyl)imidazole inhibits the reaction [daunorubicin results in increased expression of ABCB1 protein]|venetoclax inhibits the reaction [daunorubicin results in increased expression of ABCB1 protein]|[venetoclax inhibits the reaction [daunorubicin results in increased expression of ABCB1 protein]] which results in decreased export of daunorubicin|4-methyl-N1-(3-phenylpropyl)benzene-1,2-diamine inhibits the reaction [daunorubicin results in increased expression of ABCB1 protein]
|
https://ctdbase.org/detail.go?type=gene&acc=5243
|
||
|
ABCB1
|
Homo sapiens (human)
|
ABCB1 protein results in decreased susceptibility to daunorubicin|enasidenib inhibits the reaction [ABCB1 protein results in increased export of daunorubicin]|zosuquidar trihydrochloride inhibits the reaction [ABCB1 protein results in increased export of daunorubicin]|enasidenib inhibits the reaction [ABCB1 protein results in decreased susceptibility to daunorubicin]|[enasidenib inhibits the reaction [ABCB1 protein results in increased export of daunorubicin]] which results in increased susceptibility to daunorubicin
|
https://ctdbase.org/detail.go?type=gene&acc=5243
|
||
|
ABCB1
|
Homo sapiens (human)
|
ABCB1 protein results in decreased uptake of daunorubicin
|
https://ctdbase.org/detail.go?type=gene&acc=5243
|
||
|
ABCB1
|
Homo sapiens (human)
|
ABCB1 protein results in increased export of daunorubicin
|
https://ctdbase.org/detail.go?type=gene&acc=5243
|
||
|
ABCB1
|
Homo sapiens (human)
|
Naringenin inhibits the reaction [ABCB1 protein results in decreased uptake of daunorubicin]|5-hydroxyflavone inhibits the reaction [elacridar inhibits the reaction [ABCB1 protein results in decreased uptake of daunorubicin]]|elacridar inhibits the reaction [ABCB1 protein results in decreased uptake of daunorubicin]|kaempferide inhibits the reaction [ABCB1 protein results in decreased uptake of daunorubicin]|5,7-dimethoxyflavone inhibits the reaction [ABCB1 protein results in decreased uptake of daunorubicin]|flavone promotes the reaction [elacridar inhibits the reaction [ABCB1 protein results in decreased uptake of daunorubicin]]|biochanin A inhibits the reaction [ABCB1 protein results in decreased uptake of daunorubicin]|silybin inhibits the reaction [ABCB1 protein results in decreased uptake of daunorubicin]|baicalein inhibits the reaction [ABCB1 protein results in decreased uptake of daunorubicin]|schaftoside inhibits the reaction [ABCB1 protein results in decreased uptake of daunorubicin]|kaempferol inhibits the reaction [ABCB1 protein results in decreased uptake of daunorubicin]|glycitein promotes the reaction [elacridar inhibits the reaction [ABCB1 protein results in decreased uptake of daunorubicin]]|luteolin inhibits the reaction [ABCB1 protein results in decreased uptake of daunorubicin]|biochanin A promotes the reaction [elacridar inhibits the reaction [ABCB1 protein results in decreased uptake of daunorubicin]]|naringenin inhibits the reaction [elacridar inhibits the reaction [ABCB1 protein results in decreased uptake of daunorubicin]]|silybin promotes the reaction [elacridar inhibits the reaction [ABCB1 protein results in decreased uptake of daunorubicin]]|baicalein inhibits the reaction [elacridar inhibits the reaction [ABCB1 protein results in decreased uptake of daunorubicin]]|quercetin inhibits the reaction [ABCB1 protein results in decreased uptake of daunorubicin]|dihydromyricetin inhibits the reaction [ABCB1 protein results in decreased uptake of daunorubicin]|puerarin inhibits the reaction [ABCB1 protein results in decreased uptake of daunorubicin]|kaempferide inhibits the reaction [elacridar inhibits the reaction [ABCB1 protein results in decreased uptake of daunorubicin]]|5-methoxyflavone inhibits the reaction [ABCB1 protein results in decreased uptake of daunorubicin]|galangin inhibits the reaction [elacridar inhibits the reaction [ABCB1 protein results in decreased uptake of daunorubicin]]|isovitexin inhibits the reaction [ABCB1 protein results in decreased uptake of daunorubicin]|tangeretin inhibits the reaction [ABCB1 protein results in decreased uptake of daunorubicin]|flavone inhibits the reaction [ABCB1 protein results in decreased uptake of daunorubicin]|glycitein inhibits the reaction [ABCB1 protein results in decreased uptake of daunorubicin]
|
https://ctdbase.org/detail.go?type=gene&acc=5243
|
||
|
ABCB1
|
Rattus norvegicus (Norway rat)
|
ABCB1 protein affects the transport of daunorubicin
|
https://ctdbase.org/detail.go?type=gene&acc=5243
|
||
|
ABCB1
|
Rattus norvegicus (Norway rat)
|
Daunorubicin inhibits the reaction [ABCB1 results in increased transport of estradiol-17 beta-glucuronide]
|
https://ctdbase.org/detail.go?type=gene&acc=5243
|
||
|
ABCB1
|
Homo sapiens (human)
|
[5-methoxypsoralen results in decreased activity of ABCB1 protein] which results in decreased export of and results in increased abundance of daunorubicin|verapamil inhibits the reaction [[methoxsalen results in decreased activity of ABCB1 protein] which results in decreased export of and results in increased abundance of daunorubicin]|verapamil inhibits the reaction [[5-methoxypsoralen results in decreased activity of ABCB1 protein] which results in decreased export of and results in increased abundance of daunorubicin]|[methoxsalen results in decreased activity of ABCB1 protein] which results in decreased export of and results in increased abundance of daunorubicin
|
https://ctdbase.org/detail.go?type=gene&acc=5243
|
||
|
ABCB1
|
Homo sapiens (human)
|
ABCB1 affects the susceptibility to daunorubicin
|
https://ctdbase.org/detail.go?type=gene&acc=5243
|
||
|
ABCB1
|
Homo sapiens (human)
|
Daunorubicin promotes the reaction [ABCB1 mutant form results in decreased expression of ABCB1 protein]|abcb1 mutant form promotes the reaction [daunorubicin results in decreased expression of ABCB1 mrna]|abcb1 mutant form promotes the reaction [daunorubicin results in decreased expression of ABCB1 protein]|magnetite nanoparticles promotes the reaction [ABCB1 mutant form promotes the reaction [daunorubicin results in decreased expression of ABCB1 protein]]|magnetite nanoparticles promotes the reaction [daunorubicin promotes the reaction [ABCB1 mutant form results in decreased expression of ABCB1 protein]]|magnetite nanoparticles promotes the reaction [ABCB1 mutant form promotes the reaction [daunorubicin results in decreased expression of ABCB1 mrna]]
|
https://ctdbase.org/detail.go?type=gene&acc=5243
|
||
|
ABCB1
|
Homo sapiens (human)
|
ABCB1 mutant form promotes the reaction [magnetite nanoparticles results in increased susceptibility to daunorubicin]|magnetite nanoparticles promotes the reaction [daunorubicin results in decreased expression of ABCB1 mrna]|daunorubicin results in decreased expression of ABCB1 mrna|daunorubicin promotes the reaction [magnetite nanoparticles results in decreased expression of ABCB1 protein]|magnetite nanoparticles promotes the reaction [ABCB1 mutant form results in increased susceptibility to daunorubicin]|magnetite nanoparticles promotes the reaction [daunorubicin results in decreased expression of ABCB1 protein]|daunorubicin results in decreased expression of ABCB1 protein|abcb1 mutant form results in increased susceptibility to daunorubicin
|
https://ctdbase.org/detail.go?type=gene&acc=5243
|
||
|
ABCB1
|
Homo sapiens (human)
|
ABCB1 protein affects the susceptibility to daunorubicin
|
https://ctdbase.org/detail.go?type=gene&acc=5243
|
||
|
ABCB1
|
Homo sapiens (human)
|
ABCB1 protein results in increased import of daunorubicin|aurapten promotes the reaction [ABCB1 protein results in increased import of daunorubicin]|nobiletin promotes the reaction [ABCB1 protein results in increased import of daunorubicin]
|
https://ctdbase.org/detail.go?type=gene&acc=5243
|
||
|
ABCB1
|
Homo sapiens (human)
|
ABCB1 protein results in increased transport of daunorubicin
|
https://ctdbase.org/detail.go?type=gene&acc=5243
|
||
|
ABCB1
|
Homo sapiens (human)
|
Desmethylazelastine inhibits the reaction [ABCB1 protein results in increased transport of daunorubicin]|azelastine inhibits the reaction [ABCB1 protein results in increased transport of daunorubicin]|amiodarone inhibits the reaction [ABCB1 protein results in increased transport of daunorubicin]|desethylamiodarone inhibits the reaction [ABCB1 protein results in increased transport of daunorubicin]
|
https://ctdbase.org/detail.go?type=gene&acc=5243
|
||
|
ABCB1
|
Homo sapiens (human)
|
[carvedilol inhibits the reaction [ABCB1 protein results in increased transport of daunorubicin]] which results in decreased susceptibility to daunorubicin|carvedilol inhibits the reaction [ABCB1 protein results in increased transport of daunorubicin]|verapamil inhibits the reaction [ABCB1 protein results in increased transport of daunorubicin]
|
https://ctdbase.org/detail.go?type=gene&acc=5243
|
||
|
ABCB1
|
Homo sapiens (human)
|
[sodium azide co-treated with iodoacetates] inhibits the reaction [ABCB1 protein results in increased export of daunorubicin]|cyclosporine inhibits the reaction [ABCB1 protein results in increased export of daunorubicin]
|
https://ctdbase.org/detail.go?type=gene&acc=5243
|
||
|
ABCB1
|
Homo sapiens (human)
|
[daunorubicin co-treated with bromotetrandrine] results in decreased expression of ABCB1 mrna|[daunorubicin co-treated with bromotetrandrine co-treated with magnetite nanoparticles] results in decreased expression of ABCB1 mRNA
|
https://ctdbase.org/detail.go?type=gene&acc=5243
|
||
|
ABCB1
|
Homo sapiens (human)
|
[glabridin affects the activity of ABCB1 protein] which results in increased abundance of daunorubicin|[phyllodulcin affects the activity of ABCB1 protein] which results in increased abundance of daunorubicin|[glycyrrhetinic acid affects the activity of ABCB1 protein] which results in increased abundance of daunorubicin|[matairesinol affects the activity of ABCB1 protein] which results in increased abundance of daunorubicin|[ginkgolic acid affects the activity of ABCB1 protein] which results in increased abundance of daunorubicin|[sesamin affects the activity of ABCB1 protein] which results in increased abundance of daunorubicin
|
https://ctdbase.org/detail.go?type=gene&acc=5243
|
No matching records found on this page.