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Interactions between compounds and specific gene/protein targets.
| BIMP_ID | Target Name | Gene | Organism | Action | Source URL |
|---|---|---|---|---|---|
|
ABCB1
|
Homo sapiens (human)
|
Quinidine results in decreased activity of ABCB1 protein
|
https://ctdbase.org/detail.go?type=gene&acc=5243
|
||
|
ABCB1
|
Homo sapiens (human)
|
ABCB1 protein results in decreased susceptibility to deoxynivalenol|deoxynivalenol inhibits the reaction [valspodar inhibits the reaction [ABCB1 protein results in increased export of calcein AM]]
|
https://ctdbase.org/detail.go?type=gene&acc=5243
|
||
|
ABCB1
|
Homo sapiens (human)
|
2-(4-morpholinyl)-8-phenyl-4H-1-benzopyran-4-one results in decreased expression of ABCB1 protein|2-(4-morpholinyl)-8-phenyl-4H-1-benzopyran-4-one results in decreased expression of ABCB1 mRNA
|
https://ctdbase.org/detail.go?type=gene&acc=5243
|
||
|
ABCB1
|
Rattus norvegicus (Norway rat)
|
2-(4-morpholinyl)-8-phenyl-4H-1-benzopyran-4-one results in decreased expression of ABCB1 protein
|
https://ctdbase.org/detail.go?type=gene&acc=5243
|
||
|
ABCB1
|
Homo sapiens (human)
|
ABCB1 protein results in increased export of loratadine
|
https://ctdbase.org/detail.go?type=gene&acc=5243
|
||
|
ABCB1
|
Homo sapiens (human)
|
NR1I2 protein promotes the reaction [indoleacetamide results in increased expression of ABCB1 mrna]|indoleacetamide promotes the reaction [NR1I2 protein binds to ABCB1 promoter]|indoleacetamide results in increased expression of ABCB1 mRNA
|
https://ctdbase.org/detail.go?type=gene&acc=5243
|
||
|
ABCB1
|
Homo sapiens (human)
|
ABCB1 protein results in increased transport of puromycin
|
https://ctdbase.org/detail.go?type=gene&acc=5243
|
||
|
ABCB1
|
Homo sapiens (human)
|
Naringenin inhibits the reaction [elacridar inhibits the reaction [ABCB1 protein results in decreased uptake of daunorubicin]]|naringenin inhibits the reaction [ABCB1 protein results in decreased uptake of daunorubicin]|naringenin promotes the reaction [elacridar inhibits the reaction [ABCB1 protein results in decreased uptake of rhodamine 123]]
|
https://ctdbase.org/detail.go?type=gene&acc=5243
|
||
|
ABCB1
|
Homo sapiens (human)
|
Naringenin results in increased expression of ABCB1 mRNA
|
https://ctdbase.org/detail.go?type=gene&acc=5243
|
||
|
ABCB1
|
Rattus norvegicus (Norway rat)
|
6-hydroxy-2,5,7,8-tetramethylchroman-2-carboxylic acid inhibits the reaction [vitamin A results in decreased expression of ABCB1 mrna]
|
https://ctdbase.org/detail.go?type=gene&acc=5243
|
||
|
ABCB1
|
Homo sapiens (human)
|
Nicardipine inhibits the reaction [ABCB1 protein results in increased transport of digoxin]
|
https://ctdbase.org/detail.go?type=gene&acc=5243
|
||
|
ABCB1
|
Homo sapiens (human)
|
Verapamil inhibits the reaction [[methoxsalen results in decreased activity of ABCB1 protein] which results in decreased export of and results in increased abundance of daunorubicin]|[methoxsalen results in decreased activity of ABCB1 protein] which results in decreased export of and results in increased abundance of daunorubicin|methoxsalen results in decreased activity of ABCB1 protein|methoxsalen results in increased expression of ABCB1 mrna|verapamil inhibits the reaction [methoxsalen results in decreased activity of ABCB1 protein]
|
https://ctdbase.org/detail.go?type=gene&acc=5243
|
||
|
ABCB1
|
Homo sapiens (human)
|
ABCB1 protein affects the reaction [metolachlor results in increased susceptibility to paclitaxel]|metolachlor results in increased activity of ABCB1 protein
|
https://ctdbase.org/detail.go?type=gene&acc=5243
|
||
|
ABCB1
|
Homo sapiens (human)
|
3',4',7-trihydroxyisoflavone inhibits the reaction [epirubicin results in increased expression of ABCB1 mrna]
|
https://ctdbase.org/detail.go?type=gene&acc=5243
|
||
|
ABCB1
|
Homo sapiens (human)
|
ABCB1 protein affects the susceptibility to [fluorouracil co-treated with epirubicin co-treated with cyclophosphamide]
|
https://ctdbase.org/detail.go?type=gene&acc=5243
|
||
|
ABCB1
|
Homo sapiens (human)
|
[epirubicin co-treated with chrysophsin] results in increased expression of ABCB1 mrna|[epirubicin analog co-treated with chrysophsin analog] results in increased expression of ABCB1 mrna|epirubicin analog results in increased expression of ABCB1 mRNA
|
https://ctdbase.org/detail.go?type=gene&acc=5243
|
||
|
ABCB1
|
Homo sapiens (human)
|
Epirubicin results in increased expression of ABCB1 mRNA
|
https://ctdbase.org/detail.go?type=gene&acc=5243
|
||
|
ABCB1
|
Homo sapiens (human)
|
Formononetin inhibits the reaction [epirubicin results in increased expression of ABCB1 mrna]
|
https://ctdbase.org/detail.go?type=gene&acc=5243
|
||
|
ABCB1
|
Rattus norvegicus (Norway rat)
|
[diethylnitrosamine co-treated with epirubicin] results in increased expression of ABCB1 protein
|
https://ctdbase.org/detail.go?type=gene&acc=5243
|
||
|
ABCB1
|
Homo sapiens (human)
|
|
https://www.dgidb.org/genes/hgnc:40
|
||
|
ABCB1
|
Bos taurus (cattle)
|
[valspodar results in decreased activity of ABCB1 protein] promotes the reaction [mitotane results in decreased secretion of hydrocortisone]
|
https://ctdbase.org/detail.go?type=gene&acc=5243
|
||
|
ABCB1
|
Homo sapiens (human)
|
Mitotane inhibits the reaction [ABCB1 protein results in increased export of daunorubicin]
|
https://ctdbase.org/detail.go?type=gene&acc=5243
|
||
|
ABCB1
|
Homo sapiens (human)
|
Mitotane results in decreased activity of ABCB1 protein
|
https://ctdbase.org/detail.go?type=gene&acc=5243
|
||
|
ABCB1
|
Homo sapiens (human)
|
Mitotane results in increased expression of ABCB1 mRNA
|
https://ctdbase.org/detail.go?type=gene&acc=5243
|
||
|
ABCB1
|
Homo sapiens (human)
|
Mitotane results in increased expression of ABCB1 mrna|mitotane results in increased expression of ABCB1 protein
|
https://ctdbase.org/detail.go?type=gene&acc=5243
|
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