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SCFBio, IIT Delhi Hauz Khas, New Delhi

Molecular Targets

Interactions between compounds and specific gene/protein targets.

Total Rows 750,454
Pages 30,019
BIMP_ID Target Name Gene Organism Action Source URL
ABCB1
Homo sapiens (human)
Valproic acid affects the expression of ABCB1 mRNA
https://ctdbase.org/detail.go?type=gene&acc=5243
ABCB1
Homo sapiens (human)
Valproic acid results in decreased activity of ABCB1 protein
https://ctdbase.org/detail.go?type=gene&acc=5243
ABCB1
Homo sapiens (human)
Valproic acid results in decreased methylation of ABCB1 gene
https://ctdbase.org/detail.go?type=gene&acc=5243
ABCB1
Homo sapiens (human)
Valproic acid results in increased expression of ABCB1 mRNA
https://ctdbase.org/detail.go?type=gene&acc=5243
ABCB1
Rattus norvegicus (Norway rat)
Valproic acid results in increased expression of ABCB1 protein
https://ctdbase.org/detail.go?type=gene&acc=5243
ABCB1
Homo sapiens (human)
https://www.dgidb.org/genes/hgnc:40
ABCB1
Homo sapiens (human)
NR1I2 protein promotes the reaction [notoginsenoside R1 results in increased expression of ABCB1 mrna]|notoginsenoside R1 results in increased expression of ABCB1 mRNA
https://ctdbase.org/detail.go?type=gene&acc=5243
ABCB1
Homo sapiens (human)
https://www.dgidb.org/genes/hgnc:40
ABCB1
Homo sapiens (human)
ABCB1 protein results in increased transport of digitoxin
https://ctdbase.org/detail.go?type=gene&acc=5243
ABCB1
Homo sapiens (human)
Digitoxin inhibits the reaction [ABCB1 protein results in increased transport of quinidinium]
https://ctdbase.org/detail.go?type=gene&acc=5243
ABCB1
Homo sapiens (human)
https://www.dgidb.org/genes/hgnc:40
ABCB1
Homo sapiens (human)
Hyperforin inhibits the reaction [ABCB1 protein results in increased secretion of ritonavir]
https://ctdbase.org/detail.go?type=gene&acc=5243
ABCB1
Homo sapiens (human)
Hyperforin results in increased expression of ABCB1
https://ctdbase.org/detail.go?type=gene&acc=5243
ABCB1
Homo sapiens (human)
Hyperforin results in increased expression of ABCB1 mRNA
https://ctdbase.org/detail.go?type=gene&acc=5243
ABCB1
Canis lupus familiaris (dog)
[verapamil results in decreased activity of ABCB1 protein] which results in decreased transport of hypaconitine|abcb1 protein results in increased transport of hypaconitine|[cyclosporine results in decreased activity of ABCB1 protein] which results in decreased transport of hypaconitine
https://ctdbase.org/detail.go?type=gene&acc=5243
ABCB1
Homo sapiens (human)
Cymarine inhibits the reaction [ABCB1 protein results in increased transport of quinidinium]
https://ctdbase.org/detail.go?type=gene&acc=5243
ABCB1
Bos taurus (cattle)
Quinidine results in decreased activity of ABCB1 protein
https://ctdbase.org/detail.go?type=gene&acc=5243
ABCB1
Heliothis virescens (tobacco budworm)
Quinidine inhibits the reaction [ABCB1 protein results in decreased susceptibility to thiodicarb]|quinidine results in decreased activity of ABCB1 protein
https://ctdbase.org/detail.go?type=gene&acc=5243
ABCB1
Heliothis virescens (tobacco budworm)
Quinidine inhibits the reaction [ABCB1 protein results in increased export of and results in decreased susceptibility to thiodicarb]
https://ctdbase.org/detail.go?type=gene&acc=5243
ABCB1
Homo sapiens (human)
ABCB1 protein affects the transport of quinidine
https://ctdbase.org/detail.go?type=gene&acc=5243
ABCB1
Homo sapiens (human)
ABCB1 protein results in increased transport of quinidine
https://ctdbase.org/detail.go?type=gene&acc=5243
ABCB1
Homo sapiens (human)
Methoxyfenozide inhibits the reaction [ABCB1 protein results in increased transport of quinidine]|tebufenozide inhibits the reaction [ABCB1 protein results in increased transport of quinidine]
https://ctdbase.org/detail.go?type=gene&acc=5243
ABCB1
Homo sapiens (human)
Quinidine binds to ABCB1 protein
https://ctdbase.org/detail.go?type=gene&acc=5243
ABCB1
Homo sapiens (human)
Quinidine inhibits the reaction [ABCB1 protein results in decreased susceptibility to paclitaxel]|quinidine inhibits the reaction [ABCB1 protein results in decreased susceptibility to docetaxel]|quinidine results in decreased expression of ABCB1 protein
https://ctdbase.org/detail.go?type=gene&acc=5243
ABCB1
Homo sapiens (human)
Quinidine binds to ABCB1 protein
https://ctdbase.org/detail.go?type=gene&acc=5243
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