Molecular Targets : Dataset Browser

BIMP_ID	Target Name	Gene	Organism	Action	Source URL
BIMP070301	ABCB1	ABCB1	Homo sapiens (human)	Verapamil inhibits the reaction [acetaminophen results in increased activity of ABCB1 protein]	https://ctdbase.org/detail.go?type=gene&acc=5243
BIMP070301	ABCB1	ABCB1	Homo sapiens (human)	Verapamil inhibits the reaction [doxorubicin results in increased activity of ABCB1 protein]	https://ctdbase.org/detail.go?type=gene&acc=5243
BIMP070301	ABCB1	ABCB1	Homo sapiens (human)	Verapamil inhibits the reaction [tangeretin results in increased activity of ABCB1 protein]\|verapamil promotes the reaction [quercetin results in increased activity of ABCB1 protein]\|verapamil promotes the reaction [galangin results in increased activity of ABCB1 protein]\|verapamil promotes the reaction [kaempferol results in increased activity of ABCB1 protein]	https://ctdbase.org/detail.go?type=gene&acc=5243
BIMP070301	ABCB1	ABCB1	Homo sapiens (human)	Verapamil promotes the reaction [ABCB1 protein mutant form binds to 8-azidoadenosine 5'-triphosphate]	https://ctdbase.org/detail.go?type=gene&acc=5243
BIMP070301	ABCB1	ABCB1	Homo sapiens (human)	Verapamil results in decreased activity of ABCB1 protein	https://ctdbase.org/detail.go?type=gene&acc=5243
BIMP070301	ABCB1	ABCB1	Homo sapiens (human)	[verapamil results in decreased activity of ABCB1 protein] which results in decreased export of calcein AM	https://ctdbase.org/detail.go?type=gene&acc=5243
BIMP070301	ABCB1	ABCB1	Homo sapiens (human)	[verapamil results in decreased activity of ABCB1 protein] which results in decreased export of topotecan	https://ctdbase.org/detail.go?type=gene&acc=5243
BIMP070301	ABCB1	ABCB1	Homo sapiens (human)	[verapamil results in decreased activity of ABCB1 protein] which results in decreased transport of benzoylmesaconine\|[verapamil results in decreased activity of ABCB1 protein] which results in decreased transport of benzoylhypaconine\|[verapamil results in decreased activity of ABCB1 protein] which results in decreased transport of mesaconitine\|[verapamil results in decreased activity of ABCB1 protein] which results in decreased transport of hypaconitine\|[verapamil results in decreased activity of ABCB1 protein] which results in decreased transport of benzoylaconine	https://ctdbase.org/detail.go?type=gene&acc=5243
BIMP070301	ABCB1	ABCB1	Homo sapiens (human)	[verapamil results in decreased activity of ABCB1 protein] which results in decreased transport of digoxin	https://ctdbase.org/detail.go?type=gene&acc=5243
BIMP070301	ABCB1	ABCB1	Homo sapiens (human)	[verapamil results in decreased activity of ABCB1 protein] which results in increased uptake of fluorexon\|[verapamil results in decreased activity of ABCB1 protein] which results in increased susceptibility to doxorubicin	https://ctdbase.org/detail.go?type=gene&acc=5243
BIMP070301	ABCB1	ABCB1	Homo sapiens (human)	[verapamil results in decreased activity of ABCB1 protein] which results in increased susceptibility to paclitaxel	https://ctdbase.org/detail.go?type=gene&acc=5243
BIMP070301	ABCB1	ABCB1	Homo sapiens (human)	Verapamil results in decreased expression of ABCB1 protein	https://ctdbase.org/detail.go?type=gene&acc=5243
BIMP070301	ABCB1	ABCB1	Homo sapiens (human)	Verapamil results in increased activity of ABCB1 protein	https://ctdbase.org/detail.go?type=gene&acc=5243
BIMP070301	ABCB1	ABCB1	Homo sapiens (human)	Verapamil results in increased expression of ABCB1 mRNA	https://ctdbase.org/detail.go?type=gene&acc=5243
BIMP070301	ABCB1	ABCB1	Mus musculus (house mouse)	[verapamil results in decreased expression of ABCB1] promotes the reaction [doxorubicin results in increased activity of CASP3 protein]\|[verapamil results in decreased expression of ABCB1] promotes the reaction [doxorubicin results in increased activity of CASP7 protein]	https://ctdbase.org/detail.go?type=gene&acc=5243
BIMP070301	ABCB1	ABCB1	Oncorhynchus mykiss (rainbow trout)	Verapamil results in decreased activity of ABCB1 protein	https://ctdbase.org/detail.go?type=gene&acc=5243
BIMP070301	ABCB1	ABCB1	Rattus	Verapamil results in decreased activity of ABCB1 protein	https://ctdbase.org/detail.go?type=gene&acc=5243
BIMP070301	ABCB1	ABCB1	Rattus norvegicus (Norway rat)	Verapamil inhibits the reaction [ABCB1 results in decreased susceptibility to cadmium chloride]	https://ctdbase.org/detail.go?type=gene&acc=5243
BIMP070301	ABCB1	ABCB1	Rattus norvegicus (Norway rat)	[verapamil results in decreased activity of ABCB1 protein] inhibits the reaction [P-glycoprotein inducer and activator TX5 results in increased export of rhodamine 123]\|verapamil results in decreased activity of ABCB1 protein	https://ctdbase.org/detail.go?type=gene&acc=5243
BIMP070301	ABCB1	ABCB1	Rattus norvegicus (Norway rat)	Verapamil results in increased activity of ABCB1 protein	https://ctdbase.org/detail.go?type=gene&acc=5243
BIMP070301	ABCB1	ABCB1	Homo sapiens (human)	Verapamil results in increased activity of ABCB1 protein\|raloxifene-6-beta-glucuronide inhibits the reaction [verapamil results in increased activity of ABCB1 protein]\|raloxifene-4'-beta-glucuronide inhibits the reaction [verapamil results in increased activity of ABCB1 protein]\|raloxifene hydrochloride inhibits the reaction [verapamil results in increased activity of ABCB1 protein]	https://ctdbase.org/detail.go?type=gene&acc=5243
BIMP070301	ABCB1	ABCB1	Homo sapiens (human)	Verapamil metabolite binds to ABCB1 protein\|verapamil binds to ABCB1 protein	https://ctdbase.org/detail.go?type=gene&acc=5243
BIMP070301	ABCB1	ABCB1	Homo sapiens (human)	Verapamil inhibits the reaction [[ABCB1 protein co-treated with MGMT protein mutant form] results in decreased susceptibility to etoposide]	https://ctdbase.org/detail.go?type=gene&acc=5243
BIMP070301	ABCB1	ABCB1	Homo sapiens (human)	Verapamil results in decreased activity of ABCB1 protein	https://ctdbase.org/detail.go?type=gene&acc=5243
BIMP072198	ABCB1	ABCB1	Homo sapiens (human)	ABCB1 protein affects the susceptibility to valproic acid	https://ctdbase.org/detail.go?type=gene&acc=5243

BIMP070301

ABCB1

Homo sapiens (human)

Verapamil inhibits the reaction [acetaminophen results in increased activity of ABCB1 protein]