Molecular Targets : Dataset Browser

BIMP_ID	Target Name	Gene	Organism	Action	Source URL
BIMP069573	ABCB1	ABCB1	Homo sapiens (human)	[cyclosporine results in decreased activity of ABCB1 protein] which results in decreased transport of benzoylmesaconine\|[verapamil results in decreased activity of ABCB1 protein] which results in decreased transport of benzoylmesaconine\|abcb1 protein results in increased transport of benzoylmesaconine	https://ctdbase.org/detail.go?type=gene&acc=5243
BIMP069148	ABCB1	ABCB1	Homo sapiens (human)		https://www.dgidb.org/genes/hgnc:40
BIMP069148	ABCB1	ABCB1	Homo sapiens (human)	Camptothecin inhibits the reaction [rifampin results in increased expression of ABCB1 mrna]\|camptothecin results in decreased expression of ABCB1 mRNA	https://ctdbase.org/detail.go?type=gene&acc=5243
BIMP069148	ABCB1	ABCB1	Homo sapiens (human)	Camptothecin results in decreased expression of ABCB1 protein	https://ctdbase.org/detail.go?type=gene&acc=5243
BIMP069062	ABCB1	ABCB1	Homo sapiens (human)	ABCB1 affects the susceptibility to benzene	https://ctdbase.org/detail.go?type=gene&acc=5243
BIMP069062	ABCB1	ABCB1	Homo sapiens (human)	Benzene results in increased expression of ABCB1 mRNA	https://ctdbase.org/detail.go?type=gene&acc=5243
BIMP070955	ABCB1	ABCB1	Homo sapiens (human)	Butyraldehyde results in increased expression of ABCB1 mRNA	https://ctdbase.org/detail.go?type=gene&acc=5243
BIMP071048	ABCB1	ABCB1	Homo sapiens (human)	Butyric acid results in increased expression of ABCB1 mRNA	https://ctdbase.org/detail.go?type=gene&acc=5243
BIMP071078	ABCB1	ABCB1	Homo sapiens (human)	Withaferin A inhibits the reaction [[ABCB1 protein results in decreased susceptibility to doxorubicin] promotes the reaction [tetradecanoylphorbol acetate results in increased expression of ABCB1 mrna]]	https://ctdbase.org/detail.go?type=gene&acc=5243
BIMP071142	ABCB1	ABCB1	Homo sapiens (human)	Chloroquine results in decreased expression of ABCB1 mRNA	https://ctdbase.org/detail.go?type=gene&acc=5243
BIMP071142	ABCB1	ABCB1	Homo sapiens (human)	Chloroquine results in decreased expression of ABCB1 protein	https://ctdbase.org/detail.go?type=gene&acc=5243
BIMP071142	ABCB1	ABCB1	Homo sapiens (human)	Bortezomib promotes the reaction [chloroquine results in decreased expression of and results in increased nitrosation of ABCB1 protein]\|chloroquine promotes the reaction [bortezomib results in decreased expression of ABCB1 mrna]\|bortezomib promotes the reaction [chloroquine results in decreased expression of ABCB1 mrna]\|chloroquine promotes the reaction [bortezomib results in decreased expression of and results in increased nitrosation of ABCB1 protein]\|chloroquine results in decreased expression of and results in increased nitrosation of ABCB1 protein	https://ctdbase.org/detail.go?type=gene&acc=5243
BIMP071142	ABCB1	ABCB1	Homo sapiens (human)	Chloroquine promotes the reaction [cisplatin results in decreased expression of ABCB1 protein]\|chloroquine promotes the reaction [cisplatin results in decreased expression of ABCB1 mrna]	https://ctdbase.org/detail.go?type=gene&acc=5243
BIMP068861	ABCB1	ABCB1	Homo sapiens (human)	Elacridar inhibits the reaction [ABCB1 protein results in increased transport of quinacrine]\|abcb1 protein results in increased transport of quinacrine	https://ctdbase.org/detail.go?type=gene&acc=5243
BIMP068606	ABCB1	ABCB1	Homo sapiens (human)	[5-methoxypsoralen results in decreased activity of ABCB1 protein] which results in decreased export of and results in increased abundance of daunorubicin\|5-methoxypsoralen results in decreased activity of ABCB1 protein\|verapamil inhibits the reaction [[5-methoxypsoralen results in decreased activity of ABCB1 protein] which results in decreased export of and results in increased abundance of daunorubicin]\|verapamil inhibits the reaction [5-methoxypsoralen results in decreased activity of ABCB1 protein]\|5-methoxypsoralen results in increased expression of ABCB1 mRNA	https://ctdbase.org/detail.go?type=gene&acc=5243
BIMP070301	ABCB1	ABCB1	Homo sapiens (human)	Verapamil inhibits the reaction [ABCB1 protein results in increased export of doxorubicin]	https://ctdbase.org/detail.go?type=gene&acc=5243
BIMP070301	ABCB1	ABCB1	Homo sapiens (human)	Verapamil inhibits the reaction [ABCB1 protein results in increased export of fluorexon]	https://ctdbase.org/detail.go?type=gene&acc=5243
BIMP070301	ABCB1	ABCB1	Homo sapiens (human)	Verapamil inhibits the reaction [ABCB1 protein results in increased export of rhodamine 123]	https://ctdbase.org/detail.go?type=gene&acc=5243
BIMP070301	ABCB1	ABCB1	Homo sapiens (human)	Verapamil inhibits the reaction [ABCB1 protein results in increased transport of cyazofamid]	https://ctdbase.org/detail.go?type=gene&acc=5243
BIMP070301	ABCB1	ABCB1	Homo sapiens (human)	Verapamil inhibits the reaction [ABCB1 protein results in increased transport of vinblastine]\|verapamil inhibits the reaction [ABCB1 protein results in increased transport of paclitaxel]\|verapamil inhibits the reaction [ABCB1 protein results in increased transport of doxorubicin]\|verapamil inhibits the reaction [ABCB1 protein results in increased transport of daunorubicin]	https://ctdbase.org/detail.go?type=gene&acc=5243
BIMP070301	ABCB1	ABCB1	Homo sapiens (human)	Verapamil inhibits the reaction [ABCB1 protein results in increased transport of digoxin]	https://ctdbase.org/detail.go?type=gene&acc=5243
BIMP070301	ABCB1	ABCB1	Homo sapiens (human)	Verapamil inhibits the reaction [ABCB1 protein results in increased transport of huperzine A]	https://ctdbase.org/detail.go?type=gene&acc=5243
BIMP070301	ABCB1	ABCB1	Homo sapiens (human)	Verapamil inhibits the reaction [ABCB1 protein results in increased transport of quinidinium]	https://ctdbase.org/detail.go?type=gene&acc=5243
BIMP070301	ABCB1	ABCB1	Homo sapiens (human)	Verapamil inhibits the reaction [ABCB1 protein results in increased transport of sulpiride]	https://ctdbase.org/detail.go?type=gene&acc=5243
BIMP070301	ABCB1	ABCB1	Homo sapiens (human)	Verapamil inhibits the reaction [ABCB1 protein results in increased uptake of digoxin]	https://ctdbase.org/detail.go?type=gene&acc=5243

BIMP069573

ABCB1

Homo sapiens (human)

[cyclosporine results in decreased activity of ABCB1 protein] which results in decreased transport of benzoylmesaconine|[verapamil results in decreased activity of ABCB1 protein] which results in decreased transport of benzoylmesaconine|abcb1 protein results in increased transport of benzoylmesaconine

https://ctdbase.org/detail.go?type=gene&acc=5243

BIMP069148

ABCB1

Homo sapiens (human)

https://www.dgidb.org/genes/hgnc:40

BIMP069148

ABCB1

Homo sapiens (human)

Camptothecin inhibits the reaction [rifampin results in increased expression of ABCB1 mrna]|camptothecin results in decreased expression of ABCB1 mRNA

https://ctdbase.org/detail.go?type=gene&acc=5243

BIMP069148

ABCB1

Homo sapiens (human)

Camptothecin results in decreased expression of ABCB1 protein

https://ctdbase.org/detail.go?type=gene&acc=5243

BIMP069062

ABCB1

Homo sapiens (human)

ABCB1 affects the susceptibility to benzene

https://ctdbase.org/detail.go?type=gene&acc=5243

BIMP069062

ABCB1

Homo sapiens (human)

Benzene results in increased expression of ABCB1 mRNA

https://ctdbase.org/detail.go?type=gene&acc=5243

BIMP070955

ABCB1

Homo sapiens (human)

Butyraldehyde results in increased expression of ABCB1 mRNA

https://ctdbase.org/detail.go?type=gene&acc=5243

BIMP071048

ABCB1

Homo sapiens (human)

Butyric acid results in increased expression of ABCB1 mRNA

https://ctdbase.org/detail.go?type=gene&acc=5243

BIMP071078

ABCB1

Homo sapiens (human)

Withaferin A inhibits the reaction [[ABCB1 protein results in decreased susceptibility to doxorubicin] promotes the reaction [tetradecanoylphorbol acetate results in increased expression of ABCB1 mrna]]

https://ctdbase.org/detail.go?type=gene&acc=5243

BIMP071142

ABCB1

Homo sapiens (human)

Chloroquine results in decreased expression of ABCB1 mRNA

https://ctdbase.org/detail.go?type=gene&acc=5243

BIMP071142

ABCB1

Homo sapiens (human)

Chloroquine results in decreased expression of ABCB1 protein

https://ctdbase.org/detail.go?type=gene&acc=5243

BIMP071142

ABCB1

Homo sapiens (human)

Bortezomib promotes the reaction [chloroquine results in decreased expression of and results in increased nitrosation of ABCB1 protein]|chloroquine promotes the reaction [bortezomib results in decreased expression of ABCB1 mrna]|bortezomib promotes the reaction [chloroquine results in decreased expression of ABCB1 mrna]|chloroquine promotes the reaction [bortezomib results in decreased expression of and results in increased nitrosation of ABCB1 protein]|chloroquine results in decreased expression of and results in increased nitrosation of ABCB1 protein

https://ctdbase.org/detail.go?type=gene&acc=5243

BIMP071142

ABCB1

Homo sapiens (human)

Chloroquine promotes the reaction [cisplatin results in decreased expression of ABCB1 protein]|chloroquine promotes the reaction [cisplatin results in decreased expression of ABCB1 mrna]

https://ctdbase.org/detail.go?type=gene&acc=5243

BIMP068861

ABCB1

Homo sapiens (human)

Elacridar inhibits the reaction [ABCB1 protein results in increased transport of quinacrine]|abcb1 protein results in increased transport of quinacrine

https://ctdbase.org/detail.go?type=gene&acc=5243

BIMP068606

ABCB1

Homo sapiens (human)

[5-methoxypsoralen results in decreased activity of ABCB1 protein] which results in decreased export of and results in increased abundance of daunorubicin|5-methoxypsoralen results in decreased activity of ABCB1 protein|verapamil inhibits the reaction [[5-methoxypsoralen results in decreased activity of ABCB1 protein] which results in decreased export of and results in increased abundance of daunorubicin]|verapamil inhibits the reaction [5-methoxypsoralen results in decreased activity of ABCB1 protein]|5-methoxypsoralen results in increased expression of ABCB1 mRNA

https://ctdbase.org/detail.go?type=gene&acc=5243

BIMP070301

ABCB1

Homo sapiens (human)

Verapamil inhibits the reaction [ABCB1 protein results in increased export of doxorubicin]

https://ctdbase.org/detail.go?type=gene&acc=5243

BIMP070301

ABCB1

Homo sapiens (human)

Verapamil inhibits the reaction [ABCB1 protein results in increased export of fluorexon]

https://ctdbase.org/detail.go?type=gene&acc=5243

BIMP070301

ABCB1

Homo sapiens (human)

Verapamil inhibits the reaction [ABCB1 protein results in increased export of rhodamine 123]

https://ctdbase.org/detail.go?type=gene&acc=5243

BIMP070301

ABCB1

Homo sapiens (human)

Verapamil inhibits the reaction [ABCB1 protein results in increased transport of cyazofamid]

https://ctdbase.org/detail.go?type=gene&acc=5243

BIMP070301

ABCB1

Homo sapiens (human)

Verapamil inhibits the reaction [ABCB1 protein results in increased transport of vinblastine]|verapamil inhibits the reaction [ABCB1 protein results in increased transport of paclitaxel]|verapamil inhibits the reaction [ABCB1 protein results in increased transport of doxorubicin]|verapamil inhibits the reaction [ABCB1 protein results in increased transport of daunorubicin]

https://ctdbase.org/detail.go?type=gene&acc=5243

BIMP070301

ABCB1

Homo sapiens (human)

Verapamil inhibits the reaction [ABCB1 protein results in increased transport of digoxin]

https://ctdbase.org/detail.go?type=gene&acc=5243

BIMP070301

ABCB1

Homo sapiens (human)

Verapamil inhibits the reaction [ABCB1 protein results in increased transport of huperzine A]

https://ctdbase.org/detail.go?type=gene&acc=5243

BIMP070301

ABCB1

Homo sapiens (human)

Verapamil inhibits the reaction [ABCB1 protein results in increased transport of quinidinium]

https://ctdbase.org/detail.go?type=gene&acc=5243

BIMP070301

ABCB1

Homo sapiens (human)

Verapamil inhibits the reaction [ABCB1 protein results in increased transport of sulpiride]

https://ctdbase.org/detail.go?type=gene&acc=5243

BIMP070301

ABCB1

Homo sapiens (human)

Verapamil inhibits the reaction [ABCB1 protein results in increased uptake of digoxin]

https://ctdbase.org/detail.go?type=gene&acc=5243