Molecular Targets : Dataset Browser

BIMP_ID	Target Name	Gene	Organism	Action	Source URL
BIMP070301	ABCB1	ABCB1	Canis lupus familiaris (dog)	[verapamil results in decreased activity of ABCB1 protein] which affects the transport of digoxin	https://ctdbase.org/detail.go?type=gene&acc=5243
BIMP070301	ABCB1	ABCB1	Dreissena polymorpha	[verapamil results in decreased activity of ABCB1 protein] which results in decreased export of calcein am\|verapamil results in decreased activity of ABCB1 protein	https://ctdbase.org/detail.go?type=gene&acc=5243
BIMP070301	ABCB1	ABCB1	Drosophila melanogaster (fruit fly)	Verapamil inhibits the reaction [[avermectin results in increased abundance of calcium] which results in increased expression of ABCB1 protein]\|verapamil results in decreased expression of ABCB1 protein	https://ctdbase.org/detail.go?type=gene&acc=5243
BIMP070301	ABCB1	ABCB1	Gallus gallus (chicken)	[verapamil results in decreased activity of ABCB1 protein] which results in increased uptake of enrofloxacin\|verapamil results in decreased activity of ABCB1 protein	https://ctdbase.org/detail.go?type=gene&acc=5243
BIMP070301	ABCB1	ABCB1	Homo sapiens (human)	ABCB1 protein results in increased transport of verapamil	https://ctdbase.org/detail.go?type=gene&acc=5243
BIMP070301	ABCB1	ABCB1	Ovis aries (sheep)	Verapamil inhibits the reaction [ABCB1 results in decreased uptake of digoxin]	https://ctdbase.org/detail.go?type=gene&acc=5243
BIMP070301	ABCB1	ABCB1	Homo sapiens (human)	Colchicine inhibits the reaction [verapamil analog results in increased activity of ABCB1 protein mutant form]\|demecolcine inhibits the reaction [verapamil analog results in increased activity of ABCB1 protein mutant form]\|vinblastine inhibits the reaction [verapamil analog results in increased activity of ABCB1 protein mutant form]\|verapamil analog results in increased activity of ABCB1 protein mutant form\|cyclosporine inhibits the reaction [verapamil analog results in increased activity of ABCB1 protein mutant form]\|verapamil inhibits the reaction [verapamil analog results in increased activity of ABCB1 protein mutant form]	https://ctdbase.org/detail.go?type=gene&acc=5243
BIMP070301	ABCB1	ABCB1	Homo sapiens (human)	Propiconazole promotes the reaction [verapamil inhibits the reaction [ABCB1 protein results in increased transport of calcein am]]\|[endosulfan co-treated with verapamil] inhibits the reaction [ABCB1 protein results in increased transport of calcein am]\|propiconazole promotes the reaction [verapamil results in decreased activity of ABCB1 protein]\|verapamil inhibits the reaction [ABCB1 protein results in increased transport of calcein am]\|[phosalone co-treated with verapamil] inhibits the reaction [ABCB1 protein results in increased transport of calcein am]\|diazinon promotes the reaction [verapamil inhibits the reaction [ABCB1 protein results in increased transport of calcein am]]\|verapamil promotes the reaction [propiconazole results in decreased activity of ABCB1 protein]\|verapamil promotes the reaction [propiconazole inhibits the reaction [ABCB1 protein results in increased transport of calcein am]]\|diazinon promotes the reaction [verapamil results in decreased activity of ABCB1 protein]\|[endosulfan co-treated with verapamil] results in decreased activity of ABCB1 protein\|[phosalone co-treated with verapamil] results in decreased activity of ABCB1 protein	https://ctdbase.org/detail.go?type=gene&acc=5243
BIMP070301	ABCB1	ABCB1	Homo sapiens (human)	Glycyrrhetinic acid inhibits the reaction [verapamil results in increased activity of ABCB1 protein]	https://ctdbase.org/detail.go?type=gene&acc=5243
BIMP070301	ABCB1	ABCB1	Homo sapiens (human)	Verapamil affects the reaction [ABCB1 protein results in increased export of tacrolimus]	https://ctdbase.org/detail.go?type=gene&acc=5243
BIMP070301	ABCB1	ABCB1	Homo sapiens (human)	Verapamil inhibits the reaction [ABCB1 protein results in increased export of fluorescent dyes]\|verapamil binds to and affects the activity of ABCB1 protein	https://ctdbase.org/detail.go?type=gene&acc=5243
BIMP070301	ABCB1	ABCB1	Homo sapiens (human)	Verapamil binds to and results in decreased activity of ABCB1 protein	https://ctdbase.org/detail.go?type=gene&acc=5243
BIMP070301	ABCB1	ABCB1	Homo sapiens (human)	[verapamil binds to and results in decreased activity of ABCB1 protein] inhibits the reaction [sodium arsenite promotes the reaction [ABCB1 protein results in increased secretion of calcein AM]]	https://ctdbase.org/detail.go?type=gene&acc=5243
BIMP070301	ABCB1	ABCB1	Homo sapiens (human)	[verapamil binds to and results in decreased activity of ABCB1 protein] which results in decreased export of digoxin	https://ctdbase.org/detail.go?type=gene&acc=5243
BIMP070301	ABCB1	ABCB1	Homo sapiens (human)	Verapamil inhibits the reaction [ABCB1 protein results in increased transport of N-cyano-1-((3,4-dimethoxyphenyl)methyl)-3,4-dihydro-6,7-dimethoxy-N'-octyl-2(1H)-isoquinoline-carboximidamide]\|[verapamil binds to and results in decreased activity of ABCB1 protein] which results in decreased transport of N-cyano-1-((3,4-dimethoxyphenyl)methyl)-3,4-dihydro-6,7-dimethoxy-N'-octyl-2(1H)-isoquinoline-carboximidamide	https://ctdbase.org/detail.go?type=gene&acc=5243
BIMP070301	ABCB1	ABCB1	Homo sapiens (human)	[verapamil co-treated with kaempferol] results in decreased expression of ABCB1 mrna\|[verapamil co-treated with kaempferol] results in decreased expression of ABCB1 protein	https://ctdbase.org/detail.go?type=gene&acc=5243
BIMP070301	ABCB1	ABCB1	Homo sapiens (human)	Verapamil inhibits the reaction [[methoxsalen results in decreased activity of ABCB1 protein] which results in decreased export of and results in increased abundance of daunorubicin]\|verapamil inhibits the reaction [[5-methoxypsoralen results in decreased activity of ABCB1 protein] which results in decreased export of and results in increased abundance of daunorubicin]\|verapamil inhibits the reaction [5-methoxypsoralen results in decreased activity of ABCB1 protein]\|verapamil inhibits the reaction [methoxsalen results in decreased activity of ABCB1 protein]	https://ctdbase.org/detail.go?type=gene&acc=5243
BIMP070301	ABCB1	ABCB1	Homo sapiens (human)	Verapamil inhibits the reaction [ABCB1 protein affects the uptake of vinblastine]	https://ctdbase.org/detail.go?type=gene&acc=5243
BIMP070301	ABCB1	ABCB1	Homo sapiens (human)	Verapamil inhibits the reaction [ABCB1 protein results in decreased abundance of quercetin]	https://ctdbase.org/detail.go?type=gene&acc=5243
BIMP070301	ABCB1	ABCB1	Homo sapiens (human)	Verapamil inhibits the reaction [ABCB1 protein results in decreased susceptibility to doxorubicin]	https://ctdbase.org/detail.go?type=gene&acc=5243
BIMP070301	ABCB1	ABCB1	Homo sapiens (human)	Verapamil inhibits the reaction [ABCB1 protein results in decreased susceptibility to paclitaxel]	https://ctdbase.org/detail.go?type=gene&acc=5243
BIMP070301	ABCB1	ABCB1	Homo sapiens (human)	Verapamil inhibits the reaction [ABCB1 protein results in decreased susceptibility to vincristine]	https://ctdbase.org/detail.go?type=gene&acc=5243
BIMP070301	ABCB1	ABCB1	Homo sapiens (human)	Verapamil inhibits the reaction [ABCB1 protein results in decreased uptake of doxorubicin]	https://ctdbase.org/detail.go?type=gene&acc=5243
BIMP070301	ABCB1	ABCB1	Homo sapiens (human)	Verapamil inhibits the reaction [ABCB1 protein results in increased export of calcein AM]	https://ctdbase.org/detail.go?type=gene&acc=5243
BIMP069171	ABCB1	ABCB1	Homo sapiens (human)	ABCB1 affects the transport of aconitine\|abcb1 results in decreased susceptibility to aconitine	https://ctdbase.org/detail.go?type=gene&acc=5243

BIMP070301

ABCB1

Canis lupus familiaris (dog)

[verapamil results in decreased activity of ABCB1 protein] which affects the transport of digoxin