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SCFBio, IIT Delhi Hauz Khas, New Delhi

Molecular Targets

Interactions between compounds and specific gene/protein targets.

Total Rows 750,454
Pages 30,019
BIMP_ID Target Name Gene Organism Action Source URL
ABAT
Homo sapiens (human)
Inhibitor
https://www.drugbank.ca/bio_entities/BE0000253
ABAT
Homo sapiens (human)
Inhibitor
https://www.drugbank.ca/bio_entities/BE0000253
ABAT
Homo sapiens (human)
http://www.t3db.ca/biodb/bio_entities/BE0000253
ABAT
Homo sapiens (human)
Tremorgenic mycotoxins are thought to inhibit gamma-aminobutyric acid (GABA) receptors, both pre- and postsynaptic, as well as inhibit transmitter breakdown at the GABA-T receptors. this would initially increase neurotransmitter levels, potentiating the GABA-induced chloride current, then lead to decreased levels of neurotransmitter in the synapse. (A2976)
http://www.t3db.ca/biodb/bio_entities/BE0000253
ABAT
Homo sapiens (human)
Tremorgenic mycotoxins are thought to inhibit gamma-aminobutyric acid (GABA) receptors, both pre- and postsynaptic, as well as inhibit transmitter breakdown at the GABA-T receptors. this would initially increase neurotransmitter levels, potentiating the GABA-induced chloride current, then lead to decreased levels of neurotransmitter in the synapse. (A2976)
http://www.t3db.ca/biodb/bio_entities/BE0000253
ABAT
Homo sapiens (human)
https://www.drugbank.ca/bio_entities/BE0000253
ABAT
Homo sapiens (human)
http://www.t3db.ca/biodb/bio_entities/BE0000253
ABAT
Homo sapiens (human)
Valproic acid binds to and inhibits GABA transaminase. the drug's anticonvulsant activity may be related to increased brain concentrations of gamma-aminobutyric acid (GABA), an inhibitory neurotransmitter in the CNS, by inhibiting enzymes that catabolize GABA or block the reuptake of GABA into glia and nerve endings. valproic acid may also work by suppressing repetitive neuronal firing through inhibition of voltage-sensitive sodium channels.
http://www.t3db.ca/biodb/bio_entities/BE0000253
Pseudomonas putida
https://www.drugbank.ca/bio_entities/BE0002978
ipk
Shigella flexneri
https://www.drugbank.ca/bio_entities/BE0001574
FUT6
Homo sapiens (human)
https://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?tag=pol&polymerid=5147
FUT6
Homo sapiens (human)
https://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?tag=pol&polymerid=5147
ispH
Escherichia coli K-12
https://www.drugbank.ca/bio_entities/BE0004045
ispH
Escherichia coli K-12
https://www.drugbank.ca/bio_entities/BE0004045
Arthrobacter sp.
https://www.drugbank.ca/bio_entities/BE0002575
Clostridium aminobutyricum
https://www.drugbank.ca/bio_entities/BE0002977
pdxA
Escherichia coli K-12
https://www.drugbank.ca/bio_entities/BE0001581
ALDH9A1
Homo sapiens (human)
https://www.drugbank.ca/bio_entities/BE0000287
42sp43
Xenopus tropicalis (tropical clawed frog)
Ethinyl estradiol results in increased expression of 42SP43 mRNA
https://ctdbase.org/detail.go?type=gene&acc=570186
42sp50
Xenopus tropicalis (tropical clawed frog)
Ethinyl estradiol results in increased expression of 42SP50 mRNA
https://ctdbase.org/detail.go?type=gene&acc=496924
42sp50.L
Xenopus laevis (African clawed frog)
Ethinyl estradiol results in decreased expression of 42SP50.L mRNA
https://ctdbase.org/detail.go?type=gene&acc=397889
4930438A08Rikl
Rattus norvegicus (Norway rat)
Atrazine affects the methylation of 4930438A08RIKL gene
https://ctdbase.org/detail.go?type=gene&acc=287305
4930474N05Rikl1
Rattus norvegicus (Norway rat)
Indole-3-carbinol affects the expression of 4930474N05RIKL1 mRNA
https://ctdbase.org/detail.go?type=gene&acc=502163
4930488N24Rikl
Rattus norvegicus (Norway rat)
Aflatoxin B1 results in increased mutagenesis of 4930488N24RIKL gene
https://ctdbase.org/detail.go?type=gene&acc=685793
4930519F16Rikl
Rattus norvegicus (Norway rat)
Bisphenol A results in decreased expression of 4930519F16RIKL mRNA
https://ctdbase.org/detail.go?type=gene&acc=100361639
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