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Interactions between compounds and specific gene/protein targets.
| BIMP_ID | Target Name | Gene | Organism | Action | Source URL |
|---|---|---|---|---|---|
|
ABAT
|
Homo sapiens (human)
|
Inhibitor
|
https://www.drugbank.ca/bio_entities/BE0000253
|
||
|
ABAT
|
Homo sapiens (human)
|
Inhibitor
|
https://www.drugbank.ca/bio_entities/BE0000253
|
||
|
ABAT
|
Homo sapiens (human)
|
|
http://www.t3db.ca/biodb/bio_entities/BE0000253
|
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|
ABAT
|
Homo sapiens (human)
|
Tremorgenic mycotoxins are thought to inhibit gamma-aminobutyric acid (GABA) receptors, both pre- and postsynaptic, as well as inhibit transmitter breakdown at the GABA-T receptors. this would initially increase neurotransmitter levels, potentiating the GABA-induced chloride current, then lead to decreased levels of neurotransmitter in the synapse. (A2976)
|
http://www.t3db.ca/biodb/bio_entities/BE0000253
|
||
|
ABAT
|
Homo sapiens (human)
|
Tremorgenic mycotoxins are thought to inhibit gamma-aminobutyric acid (GABA) receptors, both pre- and postsynaptic, as well as inhibit transmitter breakdown at the GABA-T receptors. this would initially increase neurotransmitter levels, potentiating the GABA-induced chloride current, then lead to decreased levels of neurotransmitter in the synapse. (A2976)
|
http://www.t3db.ca/biodb/bio_entities/BE0000253
|
||
|
ABAT
|
Homo sapiens (human)
|
|
https://www.drugbank.ca/bio_entities/BE0000253
|
||
|
ABAT
|
Homo sapiens (human)
|
|
http://www.t3db.ca/biodb/bio_entities/BE0000253
|
||
|
ABAT
|
Homo sapiens (human)
|
Valproic acid binds to and inhibits GABA transaminase. the drug's anticonvulsant activity may be related to increased brain concentrations of gamma-aminobutyric acid (GABA), an inhibitory neurotransmitter in the CNS, by inhibiting enzymes that catabolize GABA or block the reuptake of GABA into glia and nerve endings. valproic acid may also work by suppressing repetitive neuronal firing through inhibition of voltage-sensitive sodium channels.
|
http://www.t3db.ca/biodb/bio_entities/BE0000253
|
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|
|
Pseudomonas putida
|
|
https://www.drugbank.ca/bio_entities/BE0002978
|
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|
ipk
|
Shigella flexneri
|
|
https://www.drugbank.ca/bio_entities/BE0001574
|
||
|
FUT6
|
Homo sapiens (human)
|
|
https://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?tag=pol&polymerid=5147
|
||
|
FUT6
|
Homo sapiens (human)
|
|
https://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?tag=pol&polymerid=5147
|
||
|
ispH
|
Escherichia coli K-12
|
|
https://www.drugbank.ca/bio_entities/BE0004045
|
||
|
ispH
|
Escherichia coli K-12
|
|
https://www.drugbank.ca/bio_entities/BE0004045
|
||
|
|
Arthrobacter sp.
|
|
https://www.drugbank.ca/bio_entities/BE0002575
|
||
|
|
Clostridium aminobutyricum
|
|
https://www.drugbank.ca/bio_entities/BE0002977
|
||
|
pdxA
|
Escherichia coli K-12
|
|
https://www.drugbank.ca/bio_entities/BE0001581
|
||
|
ALDH9A1
|
Homo sapiens (human)
|
|
https://www.drugbank.ca/bio_entities/BE0000287
|
||
|
42sp43
|
Xenopus tropicalis (tropical clawed frog)
|
Ethinyl estradiol results in increased expression of 42SP43 mRNA
|
https://ctdbase.org/detail.go?type=gene&acc=570186
|
||
|
42sp50
|
Xenopus tropicalis (tropical clawed frog)
|
Ethinyl estradiol results in increased expression of 42SP50 mRNA
|
https://ctdbase.org/detail.go?type=gene&acc=496924
|
||
|
42sp50.L
|
Xenopus laevis (African clawed frog)
|
Ethinyl estradiol results in decreased expression of 42SP50.L mRNA
|
https://ctdbase.org/detail.go?type=gene&acc=397889
|
||
|
4930438A08Rikl
|
Rattus norvegicus (Norway rat)
|
Atrazine affects the methylation of 4930438A08RIKL gene
|
https://ctdbase.org/detail.go?type=gene&acc=287305
|
||
|
4930474N05Rikl1
|
Rattus norvegicus (Norway rat)
|
Indole-3-carbinol affects the expression of 4930474N05RIKL1 mRNA
|
https://ctdbase.org/detail.go?type=gene&acc=502163
|
||
|
4930488N24Rikl
|
Rattus norvegicus (Norway rat)
|
Aflatoxin B1 results in increased mutagenesis of 4930488N24RIKL gene
|
https://ctdbase.org/detail.go?type=gene&acc=685793
|
||
|
4930519F16Rikl
|
Rattus norvegicus (Norway rat)
|
Bisphenol A results in decreased expression of 4930519F16RIKL mRNA
|
https://ctdbase.org/detail.go?type=gene&acc=100361639
|
No matching records found on this page.