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Interactions between compounds and specific gene/protein targets.
| BIMP_ID | Target Name | Gene | Organism | Action | Source URL |
|---|---|---|---|---|---|
|
ABL1
|
Homo sapiens (human)
|
Testosterone results in increased expression of ABL1 mrna|[testosterone co-treated with calcitriol] results in increased expression of ABL1 mRNA
|
https://ctdbase.org/detail.go?type=gene&acc=25
|
||
|
ABL1
|
Mus musculus (house mouse)
|
Ethinyl estradiol affects the expression of ABL1 mRNA
|
https://ctdbase.org/detail.go?type=gene&acc=25
|
||
|
ABL1
|
Mus musculus (house mouse)
|
Ethinyl estradiol results in increased expression of ABL1 mrna|[tetrachlorodibenzodioxin co-treated with ethinyl estradiol] results in increased expression of ABL1 mRNA
|
https://ctdbase.org/detail.go?type=gene&acc=25
|
||
|
ABL1
|
Rattus norvegicus (Norway rat)
|
Phenylephrine results in increased phosphorylation of ABL1 protein|abl1 protein affects the reaction [phenylephrine promotes the reaction [CRK protein binds to WASL protein]]|abl1 protein affects the susceptibility to phenylephrine|abl1 protein affects the reaction [phenylephrine promotes the reaction [BCAR1 protein binds to CRK protein]]|abl1 protein affects the reaction [phenylephrine results in increased phosphorylation of BCAR1 protein]
|
https://ctdbase.org/detail.go?type=gene&acc=25
|
||
|
ABL1
|
Homo sapiens (human)
|
[alvocidib co-treated with bortezomib co-treated with ABL1 protein] results in decreased phosphorylation of LYN protein|[alvocidib co-treated with bortezomib] results in decreased expression of ABL1 protein|[alvocidib co-treated with bortezomib co-treated with ABL1] results in decreased phosphorylation of CRKL protein
|
https://ctdbase.org/detail.go?type=gene&acc=25
|
||
|
ABL1
|
Gallus gallus (chicken)
|
T-2 toxin results in decreased expression of ABL1 mRNA
|
https://ctdbase.org/detail.go?type=gene&acc=25
|
||
|
ABL1
|
Homo sapiens (human)
|
|
https://www.dgidb.org/genes/hgnc:76
|
||
|
ABL1
|
Homo sapiens (human)
|
Quercetin results in decreased expression of ABL1 protein
|
https://ctdbase.org/detail.go?type=gene&acc=25
|
||
|
ABL1
|
Homo sapiens (human)
|
Calcitriol results in increased expression of ABL1 mrna|[testosterone co-treated with calcitriol] results in increased expression of ABL1 mRNA
|
https://ctdbase.org/detail.go?type=gene&acc=25
|
||
|
ABL1
|
Homo sapiens (human)
|
|
https://www.dgidb.org/genes/hgnc:76
|
||
|
ABL1
|
Homo sapiens (human)
|
[estradiol co-treated with TGFB1 protein] results in increased expression of ABL1 mRNA
|
https://ctdbase.org/detail.go?type=gene&acc=25
|
||
|
ABL1
|
Mus musculus (house mouse)
|
Cytochalasin D results in increased phosphorylation of ABL1 protein|egf protein inhibits the reaction [cytochalasin D results in increased phosphorylation of ABL1 protein]
|
https://ctdbase.org/detail.go?type=gene&acc=25
|
||
|
ABL1
|
Homo sapiens (human)
|
Sorafenib inhibits the reaction [[ABL1 protein mutant form co-treated with adenosine triphosphate] results in increased phosphorylation of CRKL protein]|[abl1 protein mutant form co-treated with adenosine triphosphate] results in increased phosphorylation of CRKL protein
|
https://ctdbase.org/detail.go?type=gene&acc=25
|
||
|
ABL1
|
Homo sapiens (human)
|
ABL1 protein mutant form results in increased chemical synthesis of adenosine triphosphate
|
https://ctdbase.org/detail.go?type=gene&acc=25
|
||
|
ABL1
|
Homo sapiens (human)
|
ABL1 protein results in increased susceptibility to estrogens
|
https://ctdbase.org/detail.go?type=gene&acc=25
|
||
|
ABL1
|
Mus musculus (house mouse)
|
Genistein results in increased expression of ABL1 mRNA
|
https://ctdbase.org/detail.go?type=gene&acc=25
|
||
|
ABL1
|
Homo sapiens (human)
|
|
https://www.dgidb.org/genes/hgnc:76
|
||
|
ABL1
|
Homo sapiens (human)
|
Rottlerin inhibits the reaction [[ABL1 protein results in increased phosphorylation of and results in decreased activity of PPARG protein] which results in increased expression of COL1A1 protein]
|
https://ctdbase.org/detail.go?type=gene&acc=25
|
||
|
ABL1
|
Homo sapiens (human)
|
Mangiferin results in decreased expression of ABL1 mRNA
|
https://ctdbase.org/detail.go?type=gene&acc=25
|
||
|
ABL2
|
Homo sapiens (human)
|
Testosterone results in decreased expression of ABL2 mRNA
|
https://ctdbase.org/detail.go?type=gene&acc=27
|
||
|
ABL2
|
Homo sapiens (human)
|
Arsenite inhibits the reaction [G3BP1 protein binds to ABL2 mrna]
|
https://ctdbase.org/detail.go?type=gene&acc=27
|
||
|
ABL2
|
Homo sapiens (human)
|
Cyclosporine results in increased expression of ABL2 mRNA
|
https://ctdbase.org/detail.go?type=gene&acc=27
|
||
|
ABL2
|
Gallus gallus (chicken)
|
T-2 toxin results in decreased expression of ABL2 mRNA
|
https://ctdbase.org/detail.go?type=gene&acc=27
|
||
|
ABL2
|
Homo sapiens (human)
|
[estradiol co-treated with TGFB1 protein] results in increased expression of ABL2 mRNA
|
https://ctdbase.org/detail.go?type=gene&acc=27
|
||
|
ABL2
|
Homo sapiens (human)
|
Estradiol results in increased expression of ABL2 mRNA
|
https://ctdbase.org/detail.go?type=gene&acc=27
|
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