Molecular Targets : Dataset Browser

BIMP_ID	Target Name	Gene	Organism	Action	Source URL
BIMP037097	ABL1	ABL1	Homo sapiens (human)	Abrine results in increased expression of ABL1 mRNA	https://ctdbase.org/detail.go?type=gene&acc=25
BIMP066605	ABL1	ABL1	Homo sapiens (human)		https://www.dgidb.org/genes/hgnc:76
BIMP066605	ABL1	ABL1	Homo sapiens (human)	Sorafenib results in decreased activity of ABL1 protein mutant form\|sorafenib inhibits the reaction [[ABL1 protein mutant form co-treated with adenosine triphosphate] results in increased phosphorylation of CRKL protein]\|sorafenib results in decreased phosphorylation of ABL1 protein mutant form	https://ctdbase.org/detail.go?type=gene&acc=25
BIMP034250	ABL1	ABL1	Homo sapiens (human)	Capsaicin results in increased expression of ABL1 mRNA	https://ctdbase.org/detail.go?type=gene&acc=25
BIMP026486	ABL1	ABL1	Mus musculus (house mouse)	[methylnitronitrosoguanidine co-treated with cadmium chloride] results in increased expression of ABL1 mrna\|[methylnitronitrosoguanidine co-treated with okadaic acid] results in increased expression of ABL1 mrna\|[methylnitronitrosoguanidine co-treated with tetradecanoylphorbol acetate] results in increased expression of ABL1 mRNA	https://ctdbase.org/detail.go?type=gene&acc=25
BIMP072841	ABL1	ABL1	Homo sapiens (human)	Glyphosate results in increased expression of ABL1 mRNA	https://ctdbase.org/detail.go?type=gene&acc=25
BIMP073133	ABL1	ABL1	Homo sapiens (human)	Gallic acid promotes the reaction [imatinib mesylate results in decreased phosphorylation of [BCR protein mutant form binds to ABL1 protein mutant form]]\|gallic acid results in decreased phosphorylation of [BCR protein mutant form binds to ABL1 protein mutant form]\|imatinib mesylate promotes the reaction [gallic acid results in decreased phosphorylation of [BCR protein mutant form binds to ABL1 protein mutant form]]	https://ctdbase.org/detail.go?type=gene&acc=25
BIMP073073	ABL1	ABL1	Homo sapiens (human)		https://www.dgidb.org/genes/hgnc:76
BIMP077135	ABL1	ABL1	Homo sapiens (human)	Resveratrol results in decreased expression of [BCR protein mutant form binds to ABL1 protein mutant form]\|purmorphamine inhibits the reaction [resveratrol results in decreased expression of [BCR protein mutant form binds to ABL1 protein mutant form]]	https://ctdbase.org/detail.go?type=gene&acc=25
BIMP078290	ABL1	ABL1	Mus musculus (house mouse)	Myrtucommulone A results in decreased expression of ABL1 mRNA	https://ctdbase.org/detail.go?type=gene&acc=25
BIMP078487	ABL1	ABL1	Mus musculus (house mouse)	Cocaine affects the expression of ABL1 mRNA	https://ctdbase.org/detail.go?type=gene&acc=25
BIMP073537	ABL1	ABL1	Homo sapiens (human)	2-(4-morpholinyl)-8-phenyl-4H-1-benzopyran-4-one inhibits the reaction [[BCR protein mutant form binds to ABL1 protein mutant form] which results in increased chemical synthesis of histamine]\|2-(4-morpholinyl)-8-phenyl-4H-1-benzopyran-4-one inhibits the reaction [[BCR protein mutant form binds to ABL1 protein mutant form] which results in increased expression of HDC mrna]	https://ctdbase.org/detail.go?type=gene&acc=25
BIMP074172	ABL1	ABL1	Homo sapiens (human)	Myristicin results in decreased expression of ABL1 mRNA	https://ctdbase.org/detail.go?type=gene&acc=25
BIMP074364	ABL1	ABL1	Homo sapiens (human)	Beta-glucans results in decreased expression of ABL1 mRNA	https://ctdbase.org/detail.go?type=gene&acc=25
BIMP072198	ABL1	ABL1	Homo sapiens (human)	Valproic acid affects the expression of ABL1 mRNA	https://ctdbase.org/detail.go?type=gene&acc=25
BIMP072198	ABL1	ABL1	Mus musculus (house mouse)	Valproic acid results in increased expression of ABL1 mRNA	https://ctdbase.org/detail.go?type=gene&acc=25
BIMP072300	ABL1	ABL1	Homo sapiens (human)	[[[doxorubicin co-treated with 2,5,7,8-tetramethyl-2R-(4R,8R,12-trimethyltridecyl)chroman-6-yloxy acetic acid] results in increased phosphorylation of ABL1 protein] which results in increased expression of TP73 protein] which results in decreased expression of BCL2 protein\|[[[doxorubicin co-treated with 2,5,7,8-tetramethyl-2R-(4R,8R,12-trimethyltridecyl)chroman-6-yloxy acetic acid] results in increased phosphorylation of ABL1 protein] which results in increased expression of TP73 protein] which results in increased expression of PMAIP1 protein\|[[[doxorubicin co-treated with 2,5,7,8-tetramethyl-2R-(4R,8R,12-trimethyltridecyl)chroman-6-yloxy acetic acid] results in increased phosphorylation of ABL1 protein] which results in increased expression of TP73 protein] which results in increased expression of FAS protein\|[doxorubicin co-treated with 2,5,7,8-tetramethyl-2R-(4R,8R,12-trimethyltridecyl)chroman-6-yloxy acetic acid] results in increased phosphorylation of ABL1 protein\|[[doxorubicin co-treated with 2,5,7,8-tetramethyl-2R-(4R,8R,12-trimethyltridecyl)chroman-6-yloxy acetic acid] results in increased phosphorylation of ABL1 protein] which results in increased expression of TP73 protein\|[[[doxorubicin co-treated with 2,5,7,8-tetramethyl-2R-(4R,8R,12-trimethyltridecyl)chroman-6-yloxy acetic acid] results in increased phosphorylation of ABL1 protein] which results in increased expression of TP73 protein] which results in increased expression of BAX protein\|[[[doxorubicin co-treated with 2,5,7,8-tetramethyl-2R-(4R,8R,12-trimethyltridecyl)chroman-6-yloxy acetic acid] results in increased phosphorylation of ABL1 protein] which results in increased expression of TP73 protein] which results in increased expression of TNFRSF10B protein	https://ctdbase.org/detail.go?type=gene&acc=25
BIMP072300	ABL1	ABL1	Homo sapiens (human)	[TP53 protein affects the susceptibility to doxorubicin] which affects the expression of ABL1 mRNA	https://ctdbase.org/detail.go?type=gene&acc=25
BIMP072381	ABL1	ABL1	Homo sapiens (human)	Coumarin results in decreased phosphorylation of ABL1 protein	https://ctdbase.org/detail.go?type=gene&acc=25
BIMP071352	ABL1	ABL1	Homo sapiens (human)		https://www.dgidb.org/genes/hgnc:76
BIMP071712	ABL1	ABL1	Homo sapiens (human)	ABL1 results in decreased susceptibility to daunorubicin	https://ctdbase.org/detail.go?type=gene&acc=25
BIMP070955	ABL1	ABL1	Homo sapiens (human)	Butyraldehyde results in decreased expression of ABL1 mRNA	https://ctdbase.org/detail.go?type=gene&acc=25
BIMP071142	ABL1	ABL1	Homo sapiens (human)	Chloroquine promotes the reaction [ABL1 protein mutant form binds to YWHAQ protein]\|chloroquine promotes the reaction [ABL1 protein mutant form binds to BECN1 protein]	https://ctdbase.org/detail.go?type=gene&acc=25
BIMP068482	ABL1	ABL1	Homo sapiens (human)	Benzo(a)pyrene affects the methylation of ABL1 5' UTR	https://ctdbase.org/detail.go?type=gene&acc=25
BIMP070286	ABL1	ABL1	Homo sapiens (human)	Caffeine affects the phosphorylation of ABL1 protein	https://ctdbase.org/detail.go?type=gene&acc=25

BIMP037097

ABL1

Homo sapiens (human)

Abrine results in increased expression of ABL1 mRNA

https://ctdbase.org/detail.go?type=gene&acc=25

BIMP066605

ABL1

Homo sapiens (human)

https://www.dgidb.org/genes/hgnc:76

BIMP066605

ABL1

Homo sapiens (human)

Sorafenib results in decreased activity of ABL1 protein mutant form|sorafenib inhibits the reaction [[ABL1 protein mutant form co-treated with adenosine triphosphate] results in increased phosphorylation of CRKL protein]|sorafenib results in decreased phosphorylation of ABL1 protein mutant form

https://ctdbase.org/detail.go?type=gene&acc=25

BIMP034250

ABL1

Homo sapiens (human)

Capsaicin results in increased expression of ABL1 mRNA

https://ctdbase.org/detail.go?type=gene&acc=25

BIMP026486

ABL1

Mus musculus (house mouse)

[methylnitronitrosoguanidine co-treated with cadmium chloride] results in increased expression of ABL1 mrna|[methylnitronitrosoguanidine co-treated with okadaic acid] results in increased expression of ABL1 mrna|[methylnitronitrosoguanidine co-treated with tetradecanoylphorbol acetate] results in increased expression of ABL1 mRNA

https://ctdbase.org/detail.go?type=gene&acc=25

BIMP072841

ABL1

Homo sapiens (human)

Glyphosate results in increased expression of ABL1 mRNA

https://ctdbase.org/detail.go?type=gene&acc=25

BIMP073133

ABL1

Homo sapiens (human)

Gallic acid promotes the reaction [imatinib mesylate results in decreased phosphorylation of [BCR protein mutant form binds to ABL1 protein mutant form]]|gallic acid results in decreased phosphorylation of [BCR protein mutant form binds to ABL1 protein mutant form]|imatinib mesylate promotes the reaction [gallic acid results in decreased phosphorylation of [BCR protein mutant form binds to ABL1 protein mutant form]]

https://ctdbase.org/detail.go?type=gene&acc=25

BIMP073073

ABL1

Homo sapiens (human)

https://www.dgidb.org/genes/hgnc:76

BIMP077135

ABL1

Homo sapiens (human)

Resveratrol results in decreased expression of [BCR protein mutant form binds to ABL1 protein mutant form]|purmorphamine inhibits the reaction [resveratrol results in decreased expression of [BCR protein mutant form binds to ABL1 protein mutant form]]

https://ctdbase.org/detail.go?type=gene&acc=25

BIMP078290

ABL1

Mus musculus (house mouse)

Myrtucommulone A results in decreased expression of ABL1 mRNA

https://ctdbase.org/detail.go?type=gene&acc=25

BIMP078487

ABL1

Mus musculus (house mouse)

Cocaine affects the expression of ABL1 mRNA

https://ctdbase.org/detail.go?type=gene&acc=25

BIMP073537

ABL1

Homo sapiens (human)

2-(4-morpholinyl)-8-phenyl-4H-1-benzopyran-4-one inhibits the reaction [[BCR protein mutant form binds to ABL1 protein mutant form] which results in increased chemical synthesis of histamine]|2-(4-morpholinyl)-8-phenyl-4H-1-benzopyran-4-one inhibits the reaction [[BCR protein mutant form binds to ABL1 protein mutant form] which results in increased expression of HDC mrna]

https://ctdbase.org/detail.go?type=gene&acc=25

BIMP074172

ABL1

Homo sapiens (human)

Myristicin results in decreased expression of ABL1 mRNA

https://ctdbase.org/detail.go?type=gene&acc=25

BIMP074364

ABL1

Homo sapiens (human)

Beta-glucans results in decreased expression of ABL1 mRNA

https://ctdbase.org/detail.go?type=gene&acc=25

BIMP072198

ABL1

Homo sapiens (human)

Valproic acid affects the expression of ABL1 mRNA

https://ctdbase.org/detail.go?type=gene&acc=25

BIMP072198

ABL1

Mus musculus (house mouse)

Valproic acid results in increased expression of ABL1 mRNA

https://ctdbase.org/detail.go?type=gene&acc=25

BIMP072300

ABL1

Homo sapiens (human)

[[[doxorubicin co-treated with 2,5,7,8-tetramethyl-2R-(4R,8R,12-trimethyltridecyl)chroman-6-yloxy acetic acid] results in increased phosphorylation of ABL1 protein] which results in increased expression of TP73 protein] which results in decreased expression of BCL2 protein|[[[doxorubicin co-treated with 2,5,7,8-tetramethyl-2R-(4R,8R,12-trimethyltridecyl)chroman-6-yloxy acetic acid] results in increased phosphorylation of ABL1 protein] which results in increased expression of TP73 protein] which results in increased expression of PMAIP1 protein|[[[doxorubicin co-treated with 2,5,7,8-tetramethyl-2R-(4R,8R,12-trimethyltridecyl)chroman-6-yloxy acetic acid] results in increased phosphorylation of ABL1 protein] which results in increased expression of TP73 protein] which results in increased expression of FAS protein|[doxorubicin co-treated with 2,5,7,8-tetramethyl-2R-(4R,8R,12-trimethyltridecyl)chroman-6-yloxy acetic acid] results in increased phosphorylation of ABL1 protein|[[doxorubicin co-treated with 2,5,7,8-tetramethyl-2R-(4R,8R,12-trimethyltridecyl)chroman-6-yloxy acetic acid] results in increased phosphorylation of ABL1 protein] which results in increased expression of TP73 protein|[[[doxorubicin co-treated with 2,5,7,8-tetramethyl-2R-(4R,8R,12-trimethyltridecyl)chroman-6-yloxy acetic acid] results in increased phosphorylation of ABL1 protein] which results in increased expression of TP73 protein] which results in increased expression of BAX protein|[[[doxorubicin co-treated with 2,5,7,8-tetramethyl-2R-(4R,8R,12-trimethyltridecyl)chroman-6-yloxy acetic acid] results in increased phosphorylation of ABL1 protein] which results in increased expression of TP73 protein] which results in increased expression of TNFRSF10B protein

https://ctdbase.org/detail.go?type=gene&acc=25

BIMP072300

ABL1

Homo sapiens (human)

[TP53 protein affects the susceptibility to doxorubicin] which affects the expression of ABL1 mRNA

https://ctdbase.org/detail.go?type=gene&acc=25

BIMP072381

ABL1

Homo sapiens (human)

Coumarin results in decreased phosphorylation of ABL1 protein

https://ctdbase.org/detail.go?type=gene&acc=25

BIMP071352

ABL1

Homo sapiens (human)

https://www.dgidb.org/genes/hgnc:76

BIMP071712

ABL1

Homo sapiens (human)

ABL1 results in decreased susceptibility to daunorubicin

https://ctdbase.org/detail.go?type=gene&acc=25

BIMP070955

ABL1

Homo sapiens (human)

Butyraldehyde results in decreased expression of ABL1 mRNA

https://ctdbase.org/detail.go?type=gene&acc=25

BIMP071142

ABL1

Homo sapiens (human)

Chloroquine promotes the reaction [ABL1 protein mutant form binds to YWHAQ protein]|chloroquine promotes the reaction [ABL1 protein mutant form binds to BECN1 protein]

https://ctdbase.org/detail.go?type=gene&acc=25

BIMP068482

ABL1

Homo sapiens (human)

Benzo(a)pyrene affects the methylation of ABL1 5' UTR

https://ctdbase.org/detail.go?type=gene&acc=25

BIMP070286

ABL1

Homo sapiens (human)

Caffeine affects the phosphorylation of ABL1 protein

https://ctdbase.org/detail.go?type=gene&acc=25