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Interactions between compounds and specific gene/protein targets.
| BIMP_ID | Target Name | Gene | Organism | Action | Source URL |
|---|---|---|---|---|---|
|
ABCC5
|
Homo sapiens (human)
|
|
https://www.dgidb.org/genes/hgnc:56
|
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ABCC5
|
Homo sapiens (human)
|
ABCC5 protein results in increased export of zidovudine
|
https://ctdbase.org/detail.go?type=gene&acc=10057
|
||
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ABCC5
|
Homo sapiens (human)
|
Zidovudine results in increased expression of ABCC5 mRNA
|
https://ctdbase.org/detail.go?type=gene&acc=10057
|
||
|
ABCC5
|
Homo sapiens (human)
|
ABCC5 protein results in increased export of zidovudine
|
https://ctdbase.org/detail.go?type=gene&acc=10057
|
||
|
ABCC5
|
Mytilus galloprovincialis (Mediterranean mussel)
|
Glyphosate results in decreased expression of ABCC5 mRNA
|
https://ctdbase.org/detail.go?type=gene&acc=10057
|
||
|
ABCC5
|
Homo sapiens (human)
|
|
https://www.dgidb.org/genes/hgnc:56
|
||
|
ABCC5
|
Homo sapiens (human)
|
[INS protein co-treated with dexamethasone co-treated with 1-methyl-3-isobutylxanthine co-treated with indomethacin co-treated with bisphenol S] results in decreased expression of ABCC5 mRNA
|
https://ctdbase.org/detail.go?type=gene&acc=10057
|
||
|
ABCC5
|
Rattus norvegicus (Norway rat)
|
Gentamicins results in increased expression of ABCC5 mRNA
|
https://ctdbase.org/detail.go?type=gene&acc=10057
|
||
|
ABCC5
|
Homo sapiens (human)
|
|
https://www.dgidb.org/genes/hgnc:56
|
||
|
ABCC5
|
Homo sapiens (human)
|
ABCC5 protein results in increased export of and results in decreased susceptibility to fluorouracil|5-nitro-2-(3-phenylpropylamino)benzoic acid inhibits the reaction [ABCC5 protein results in decreased susceptibility to fluorouracil]
|
https://ctdbase.org/detail.go?type=gene&acc=10057
|
||
|
ABCC5
|
Homo sapiens (human)
|
ABCC5 protein results in decreased susceptibility to fluorouracil
|
https://ctdbase.org/detail.go?type=gene&acc=10057
|
||
|
ABCC5
|
Homo sapiens (human)
|
Zoledronic acid results in decreased expression of ABCC5 mRNA
|
https://ctdbase.org/detail.go?type=gene&acc=10057
|
||
|
ABCC5
|
Mus musculus (house mouse)
|
[carbon tetrachloride co-treated with ethanol] results in increased expression of ABCC5 mRNA
|
https://ctdbase.org/detail.go?type=gene&acc=10057
|
||
|
ABCC5
|
Mus musculus (house mouse)
|
Lithocholic acid results in increased expression of ABCC5 protein|[lithocholic acid co-treated with oltipraz] results in increased expression of ABCC5 protein
|
https://ctdbase.org/detail.go?type=gene&acc=10057
|
||
|
ABCC5
|
Mus musculus (house mouse)
|
Lithocholic acid results in increased expression of ABCC5 mRNA
|
https://ctdbase.org/detail.go?type=gene&acc=10057
|
||
|
ABCC5
|
Mus musculus (house mouse)
|
NFE2L2 protein promotes the reaction [lithocholic acid results in increased expression of ABCC5 mrna]
|
https://ctdbase.org/detail.go?type=gene&acc=10057
|
||
|
ABCC5
|
Mus musculus (house mouse)
|
[benzo(a)pyrene co-treated with benz(a)anthracene co-treated with benzo(b)fluoranthene co-treated with chrysene] results in decreased expression of ABCC5 mRNA
|
https://ctdbase.org/detail.go?type=gene&acc=10057
|
||
|
ABCC5
|
Mus musculus (house mouse)
|
Chrysene results in decreased expression of ABCC5 mRNA
|
https://ctdbase.org/detail.go?type=gene&acc=10057
|
||
|
ABCC5
|
Rattus norvegicus (Norway rat)
|
Furan results in increased expression of ABCC5 mRNA
|
https://ctdbase.org/detail.go?type=gene&acc=10057
|
||
|
ABCC5
|
Homo sapiens (human)
|
Benzo(e)pyrene results in increased methylation of ABCC5 intron
|
https://ctdbase.org/detail.go?type=gene&acc=10057
|
||
|
ABCC5
|
Homo sapiens (human)
|
Curcumin binds to and results in decreased activity of ABCC5 protein|[curcumin analog binds to and results in decreased activity of ABCC5 protein] which results in decreased export of hyaluronic acid|curcumin inhibits the reaction [ABCC5 protein results in increased export of hyaluronic acid]|[curcumin binds to and results in decreased activity of ABCC5 protein] which results in decreased export of hyaluronic acid|curcumin analog inhibits the reaction [ABCC5 protein results in increased export of hyaluronic acid]|curcumin analog binds to and results in decreased activity of ABCC5 protein
|
https://ctdbase.org/detail.go?type=gene&acc=10057
|
||
|
ABCC5
|
Xenopus tropicalis (tropical clawed frog)
|
Dimethyl phthalate results in increased expression of ABCC5 mRNA
|
https://ctdbase.org/detail.go?type=gene&acc=10057
|
||
|
ABCC5
|
Homo sapiens (human)
|
Bisphenol A analog results in increased expression of ABCC5 mRNA
|
https://ctdbase.org/detail.go?type=gene&acc=10057
|
||
|
ABCC5
|
Homo sapiens (human)
|
Bisphenol A results in decreased expression of ABCC5 mRNA
|
https://ctdbase.org/detail.go?type=gene&acc=10057
|
||
|
ABCC5
|
Homo sapiens (human)
|
Bisphenol A results in increased expression of ABCC5 mRNA
|
https://ctdbase.org/detail.go?type=gene&acc=10057
|
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