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Interactions between compounds and specific gene/protein targets.
| BIMP_ID | Target Name | Gene | Organism | Action | Source URL |
|---|---|---|---|---|---|
|
ABCC5
|
Rattus norvegicus (Norway rat)
|
Dimethylnitrosamine results in increased expression of ABCC5 mRNA
|
https://ctdbase.org/detail.go?type=gene&acc=10057
|
||
|
ABCC5
|
Mus musculus (house mouse)
|
Dibutyl phthalate results in decreased expression of ABCC5 mrna|dibutyl phthalate results in increased expression of ABCC5 mRNA
|
https://ctdbase.org/detail.go?type=gene&acc=10057
|
||
|
ABCC5
|
Mus musculus (house mouse)
|
[methionine deficiency co-treated with choline deficiency co-treated with folic acid deficiency] results in decreased methylation of and results in increased expression of abcc5|[methionine deficiency co-treated with choline deficiency co-treated with folic acid deficiency] results in increased expression of ABCC5 mrna|[methionine deficiency co-treated with choline deficiency co-treated with folic acid deficiency] results in decreased methylation of ABCC5 gene
|
https://ctdbase.org/detail.go?type=gene&acc=10057
|
||
|
ABCC5
|
Homo sapiens (human)
|
Valproic acid affects the expression of ABCC5 mRNA
|
https://ctdbase.org/detail.go?type=gene&acc=10057
|
||
|
ABCC5
|
Homo sapiens (human)
|
Valproic acid results in increased expression of ABCC5 mRNA
|
https://ctdbase.org/detail.go?type=gene&acc=10057
|
||
|
ABCC5
|
Mus musculus (house mouse)
|
Valproic acid affects the expression of ABCC5 mRNA
|
https://ctdbase.org/detail.go?type=gene&acc=10057
|
||
|
ABCC5
|
Rattus norvegicus (Norway rat)
|
Valproic acid results in increased expression of ABCC5 mRNA
|
https://ctdbase.org/detail.go?type=gene&acc=10057
|
||
|
ABCC5
|
Homo sapiens (human)
|
Naringenin inhibits the reaction [ABCC5 protein results in decreased susceptibility to thioguanine]|naringenin inhibits the reaction [ABCC5 protein results in increased export of 2',7'-bis(carboxyethyl)-5(6)-carboxyfluorescein]
|
https://ctdbase.org/detail.go?type=gene&acc=10057
|
||
|
ABCC5
|
Sus scrofa (pig)
|
Deoxynivalenol results in decreased expression of ABCC5 mRNA
|
https://ctdbase.org/detail.go?type=gene&acc=10057
|
||
|
ABCC5
|
Homo sapiens (human)
|
2-(4-morpholinyl)-8-phenyl-4H-1-benzopyran-4-one results in decreased expression of ABCC5 protein
|
https://ctdbase.org/detail.go?type=gene&acc=10057
|
||
|
ABCC5
|
Boreogadus saida
|
[benzo(a)pyrene co-treated with ethinyl estradiol] results in decreased expression of ABCC5 mRNA
|
https://ctdbase.org/detail.go?type=gene&acc=10057
|
||
|
ABCC5
|
Homo sapiens (human)
|
Benzo(a)pyrene results in decreased methylation of ABCC5 5' utr|benzo(a)pyrene results in decreased methylation of ABCC5 promoter
|
https://ctdbase.org/detail.go?type=gene&acc=10057
|
||
|
ABCC5
|
Homo sapiens (human)
|
Benzo(a)pyrene results in increased expression of ABCC5 mRNA
|
https://ctdbase.org/detail.go?type=gene&acc=10057
|
||
|
ABCC5
|
Mus musculus (house mouse)
|
[benzo(a)pyrene co-treated with benz(a)anthracene co-treated with benzo(b)fluoranthene co-treated with chrysene] results in decreased expression of ABCC5 mRNA
|
https://ctdbase.org/detail.go?type=gene&acc=10057
|
||
|
ABCC5
|
Mus musculus (house mouse)
|
Benzo(a)pyrene results in increased expression of ABCC5 mRNA
|
https://ctdbase.org/detail.go?type=gene&acc=10057
|
||
|
ABCC5
|
Homo sapiens (human)
|
Probenecid inhibits the reaction [ABCC5 protein results in decreased susceptibility to thioguanine]|5-nitro-2-(3-phenylpropylamino)benzoic acid inhibits the reaction [ABCC5 protein results in decreased susceptibility to thioguanine]|abcc5 protein results in decreased susceptibility to thioguanine
|
https://ctdbase.org/detail.go?type=gene&acc=10057
|
||
|
ABCC5
|
Homo sapiens (human)
|
Daidzein inhibits the reaction [ABCC5 protein results in decreased susceptibility to thioguanine]|naringenin inhibits the reaction [ABCC5 protein results in decreased susceptibility to thioguanine]|hesperetin inhibits the reaction [ABCC5 protein results in decreased susceptibility to thioguanine]|quercetin inhibits the reaction [ABCC5 protein results in decreased susceptibility to thioguanine]
|
https://ctdbase.org/detail.go?type=gene&acc=10057
|
||
|
ABCC5
|
Homo sapiens (human)
|
Coumarin results in decreased phosphorylation of ABCC5 protein
|
https://ctdbase.org/detail.go?type=gene&acc=10057
|
||
|
ABCC5
|
Homo sapiens (human)
|
ABCC5 protein results in decreased susceptibility to doxorubicin
|
https://ctdbase.org/detail.go?type=gene&acc=10057
|
||
|
ABCC5
|
Homo sapiens (human)
|
[NFE2L2 protein results in increased expression of [HMOX1 protein co-treated with AKR1B10 protein co-treated with ABCC5 protein]] which results in decreased susceptibility to doxorubicin|chrysin inhibits the reaction [[NFE2L2 protein results in increased expression of [HMOX1 protein co-treated with AKR1B10 protein co-treated with ABCC5 protein]] which results in decreased susceptibility to doxorubicin]
|
https://ctdbase.org/detail.go?type=gene&acc=10057
|
||
|
ABCC5
|
Homo sapiens (human)
|
Resveratrol inhibits the reaction [ABCC5 protein results in increased export of 2',7'-bis(carboxyethyl)-5(6)-carboxyfluorescein]|abcc5 protein results in decreased susceptibility to resveratrol
|
https://ctdbase.org/detail.go?type=gene&acc=10057
|
||
|
ABCC5
|
Mus musculus (house mouse)
|
[resveratrol co-treated with HMGB1 protein] results in increased expression of ABCC5 mRNA
|
https://ctdbase.org/detail.go?type=gene&acc=10057
|
||
|
ABCC5
|
Homo sapiens (human)
|
|
https://www.dgidb.org/genes/hgnc:56
|
||
|
ABCC5
|
Rattus norvegicus (Norway rat)
|
Cocaine affects the expression of ABCC5 mRNA
|
https://ctdbase.org/detail.go?type=gene&acc=10057
|
||
|
ABCC5
|
Homo sapiens (human)
|
2-butenal results in decreased expression of ABCC5 mRNA
|
https://ctdbase.org/detail.go?type=gene&acc=10057
|
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