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Interactions between compounds and specific gene/protein targets.
| BIMP_ID | Target Name | Gene | Organism | Action | Source URL |
|---|---|---|---|---|---|
|
ABCC3
|
Homo sapiens (human)
|
Isoproterenol results in increased expression of ABCC3 mrna|isoproterenol results in decreased expression of ABCC3 mRNA
|
https://ctdbase.org/detail.go?type=gene&acc=8714
|
||
|
ABCC3
|
Mus musculus (house mouse)
|
Isoproterenol results in decreased expression of ABCC3 mRNA
|
https://ctdbase.org/detail.go?type=gene&acc=8714
|
||
|
ABCC3
|
Homo sapiens (human)
|
Deoxynivalenol results in decreased expression of ABCC3 mRNA
|
https://ctdbase.org/detail.go?type=gene&acc=8714
|
||
|
ABCC3
|
Homo sapiens (human)
|
Methoxsalen results in increased expression of ABCC3 protein
|
https://ctdbase.org/detail.go?type=gene&acc=8714
|
||
|
ABCC3
|
Rattus norvegicus (Norway rat)
|
Methoxsalen results in increased expression of ABCC3 mRNA
|
https://ctdbase.org/detail.go?type=gene&acc=8714
|
||
|
ABCC3
|
Homo sapiens (human)
|
Vitamin K 3 affects the expression of ABCC3 mRNA
|
https://ctdbase.org/detail.go?type=gene&acc=8714
|
||
|
ABCC4
|
Mus musculus (house mouse)
|
Permethrin results in increased expression of ABCC4 mRNA
|
https://ctdbase.org/detail.go?type=gene&acc=10257
|
||
|
ABCC4
|
Rattus norvegicus (Norway rat)
|
[permethrin co-treated with DEET] results in decreased methylation of ABCC4 gene
|
https://ctdbase.org/detail.go?type=gene&acc=10257
|
||
|
ABCC4
|
Homo sapiens (human)
|
Kynurenic acid inhibits the reaction [ABCC4 protein results in increased export of methotrexate]
|
https://ctdbase.org/detail.go?type=gene&acc=10257
|
||
|
ABCC4
|
Mus musculus (house mouse)
|
Isoproterenol results in increased expression of ABCC4 mRNA
|
https://ctdbase.org/detail.go?type=gene&acc=10257
|
||
|
ABCC4
|
Rattus norvegicus (Norway rat)
|
Amikacin results in decreased expression of ABCC4 mRNA
|
https://ctdbase.org/detail.go?type=gene&acc=10257
|
||
|
ABCC4
|
Rattus norvegicus (Norway rat)
|
Isoniazid results in decreased expression of ABCC4 mRNA
|
https://ctdbase.org/detail.go?type=gene&acc=10257
|
||
|
ABCC4
|
Mus musculus (house mouse)
|
Methoxsalen results in increased expression of ABCC4 mrna|methoxsalen affects the expression of ABCC4 protein
|
https://ctdbase.org/detail.go?type=gene&acc=10257
|
||
|
ABCC4
|
Homo sapiens (human)
|
Naringenin promotes the reaction [ABCC4 protein results in increased hydrolysis of adenosine triphosphate]|naringenin inhibits the reaction [ABCC4 protein results in increased export of cyclic GMP]
|
https://ctdbase.org/detail.go?type=gene&acc=10257
|
||
|
ABCC4
|
Homo sapiens (human)
|
Metribolone results in increased expression of ABCC4 mRNA
|
https://ctdbase.org/detail.go?type=gene&acc=10257
|
||
|
ABCC4
|
Homo sapiens (human)
|
Verlukast inhibits the reaction [ABCC4 protein results in decreased susceptibility to thioguanine]|quercetin inhibits the reaction [ABCC4 protein results in decreased susceptibility to thioguanine]|hesperetin inhibits the reaction [ABCC4 protein results in decreased susceptibility to thioguanine]
|
https://ctdbase.org/detail.go?type=gene&acc=10257
|
||
|
ABCC4
|
Homo sapiens (human)
|
Caffeine results in increased phosphorylation of ABCC4 protein
|
https://ctdbase.org/detail.go?type=gene&acc=10257
|
||
|
ABCC4
|
Danio rerio (zebrafish)
|
[methyl parathion co-treated with verapamil] results in increased expression of ABCC4 mRNA
|
https://ctdbase.org/detail.go?type=gene&acc=10257
|
||
|
ABCC4
|
Mus musculus (house mouse)
|
[methionine co-treated with choline co-treated with folic acid co-treated with betaine co-treated with vitamin B 12 co-treated with zinc co-treated with phenobarbital] results in increased expression of ABCC4 mRNA
|
https://ctdbase.org/detail.go?type=gene&acc=10257
|
||
|
ABCC4
|
Homo sapiens (human)
|
Benzo(a)pyrene affects the methylation of ABCC4 intron
|
https://ctdbase.org/detail.go?type=gene&acc=10257
|
||
|
ABCC4
|
Homo sapiens (human)
|
Benzo(a)pyrene results in decreased expression of ABCC4 mRNA
|
https://ctdbase.org/detail.go?type=gene&acc=10257
|
||
|
ABCC4
|
Homo sapiens (human)
|
Benzo(a)pyrene affects the methylation of ABCC4 intron|benzo(a)pyrene results in decreased methylation of ABCC4 3' utr|benzo(a)pyrene results in increased methylation of ABCC4 promoter
|
https://ctdbase.org/detail.go?type=gene&acc=10257
|
||
|
ABCC4
|
Mus musculus (house mouse)
|
[benzo(a)pyrene co-treated with dextran sulfate] results in increased expression of ABCC4 mRNA
|
https://ctdbase.org/detail.go?type=gene&acc=10257
|
||
|
ABCC4
|
Mus musculus (house mouse)
|
Benzo(a)pyrene results in increased expression of ABCC4 mRNA
|
https://ctdbase.org/detail.go?type=gene&acc=10257
|
||
|
ABCC4
|
Danio rerio (zebrafish)
|
Valproic acid affects the expression of ABCC4 mRNA
|
https://ctdbase.org/detail.go?type=gene&acc=10257
|
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