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Interactions between compounds and specific gene/protein targets.
| BIMP_ID | Target Name | Gene | Organism | Action | Source URL |
|---|---|---|---|---|---|
|
ABCC3
|
Homo sapiens (human)
|
|
https://www.dgidb.org/genes/hgnc:54
|
||
|
ABCC3
|
Homo sapiens (human)
|
MAPK14 promotes the reaction [clotrimazole results in increased expression of ABCC3 mrna]|clotrimazole results in increased expression of ABCC3 mrna|sb 203580 inhibits the reaction [clotrimazole results in increased expression of ABCC3 mrna]
|
https://ctdbase.org/detail.go?type=gene&acc=8714
|
||
|
ABCC3
|
Mus musculus (house mouse)
|
[LEP gene mutant form co-treated with methionine deficiency co-treated with choline deficiency] results in increased expression of ABCC3 mrna|[lepr gene mutant form co-treated with methionine deficiency co-treated with choline deficiency] results in increased expression of ABCC3 mrna|[lepr gene mutant form co-treated with methionine deficiency co-treated with choline deficiency] results in increased expression of ABCC3 protein
|
https://ctdbase.org/detail.go?type=gene&acc=8714
|
||
|
ABCC3
|
Mus musculus (house mouse)
|
[methionine deficiency co-treated with choline deficiency co-treated with folic acid deficiency] results in decreased expression of ABCC3 mRNA
|
https://ctdbase.org/detail.go?type=gene&acc=8714
|
||
|
ABCC3
|
Rattus norvegicus (Norway rat)
|
[methionine deficiency co-treated with choline deficiency] results in increased expression of ABCC3 protein|[methionine deficiency co-treated with choline deficiency] results in increased expression of ABCC3 mRNA
|
https://ctdbase.org/detail.go?type=gene&acc=8714
|
||
|
ABCC3
|
Rattus norvegicus (Norway rat)
|
[[methionine deficiency co-treated with choline deficiency] results in increased expression of ABCC3 protein] which results in increased export of acetaminophen metabolite
|
https://ctdbase.org/detail.go?type=gene&acc=8714
|
||
|
ABCC3
|
Mus musculus (house mouse)
|
[clofibrate binds to PPARA protein] which results in increased expression of ABCC3 mRNA
|
https://ctdbase.org/detail.go?type=gene&acc=8714
|
||
|
ABCC3
|
Mus musculus (house mouse)
|
[clofibrate co-treated with acetaminophen] affects the expression of ABCC3 mrna|ppara affects the reaction [[clofibrate co-treated with acetaminophen] affects the expression of ABCC3 mrna]
|
https://ctdbase.org/detail.go?type=gene&acc=8714
|
||
|
ABCC3
|
Mus musculus (house mouse)
|
Clofibrate results in increased expression of ABCC3 mRNA
|
https://ctdbase.org/detail.go?type=gene&acc=8714
|
||
|
ABCC3
|
Mus musculus (house mouse)
|
PPARA promotes the reaction [clofibrate results in increased expression of ABCC3 mrna]|ppara promotes the reaction [clofibrate results in increased expression of ABCC3 protein]|clofibrate results in increased expression of ABCC3 protein
|
https://ctdbase.org/detail.go?type=gene&acc=8714
|
||
|
ABCC3
|
Rattus norvegicus (Norway rat)
|
Glyburide results in increased expression of ABCC3 mRNA
|
https://ctdbase.org/detail.go?type=gene&acc=8714
|
||
|
ABCC3
|
Homo sapiens (human)
|
Indomethacin inhibits the reaction [ABCC3 protein affects the export of 5-carboxyfluorescein diacetate]
|
https://ctdbase.org/detail.go?type=gene&acc=8714
|
||
|
ABCC3
|
Homo sapiens (human)
|
Indomethacin inhibits the reaction [ABCC3 protein affects the transport of estradiol-17 beta-glucuronide]
|
https://ctdbase.org/detail.go?type=gene&acc=8714
|
||
|
ABCC3
|
Homo sapiens (human)
|
Indomethacin results in increased expression of ABCC3 protein
|
https://ctdbase.org/detail.go?type=gene&acc=8714
|
||
|
ABCC3
|
Homo sapiens (human)
|
[INS protein co-treated with dexamethasone co-treated with 1-methyl-3-isobutylxanthine co-treated with indomethacin co-treated with bisphenol A] results in decreased expression of ABCC3 mrna|[ins protein co-treated with dexamethasone co-treated with 1-methyl-3-isobutylxanthine co-treated with indomethacin co-treated with bisphenol S] results in decreased expression of ABCC3 mrna|[ins protein co-treated with dexamethasone co-treated with 1-methyl-3-isobutylxanthine co-treated with indomethacin co-treated with bisphenol F] results in decreased expression of ABCC3 mRNA
|
https://ctdbase.org/detail.go?type=gene&acc=8714
|
||
|
ABCC3
|
Homo sapiens (human)
|
Zidovudine results in increased expression of ABCC3 mRNA
|
https://ctdbase.org/detail.go?type=gene&acc=8714
|
||
|
ABCC3
|
Rattus norvegicus (Norway rat)
|
Zidovudine results in decreased expression of ABCC3 mRNA
|
https://ctdbase.org/detail.go?type=gene&acc=8714
|
||
|
ABCC3
|
Rattus norvegicus (Norway rat)
|
Indole-3-carbinol affects the expression of ABCC3 mRNA
|
https://ctdbase.org/detail.go?type=gene&acc=8714
|
||
|
ABCC3
|
Rattus norvegicus (Norway rat)
|
[indole-3-carbinol co-treated with diethylnitrosamine] results in increased expression of ABCC3 mRNA
|
https://ctdbase.org/detail.go?type=gene&acc=8714
|
||
|
ABCC3
|
Homo sapiens (human)
|
ABCC3 protein results in decreased susceptibility to etoposide
|
https://ctdbase.org/detail.go?type=gene&acc=8714
|
||
|
ABCC3
|
Homo sapiens (human)
|
|
https://www.dgidb.org/genes/hgnc:54
|
||
|
ABCC3
|
Homo sapiens (human)
|
Sodium dodecyl sulfate results in increased expression of ABCC3 mRNA
|
https://ctdbase.org/detail.go?type=gene&acc=8714
|
||
|
ABCC3
|
Rattus norvegicus (Norway rat)
|
Isoniazid results in decreased expression of ABCC3 mrna|obeticholic acid inhibits the reaction [isoniazid results in decreased expression of ABCC3 mrna]
|
https://ctdbase.org/detail.go?type=gene&acc=8714
|
||
|
ABCC3
|
Rattus norvegicus (Norway rat)
|
[lipopolysaccharides co-treated with isoniazid] results in increased expression of ABCC3 mRNA
|
https://ctdbase.org/detail.go?type=gene&acc=8714
|
||
|
ABCC3
|
Rattus norvegicus (Norway rat)
|
Amikacin results in decreased expression of ABCC3 mRNA
|
https://ctdbase.org/detail.go?type=gene&acc=8714
|
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