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SCFBio, IIT Delhi Hauz Khas, New Delhi

Molecular Targets

Interactions between compounds and specific gene/protein targets.

Total Rows 750,454
Pages 30,019
BIMP_ID Target Name Gene Organism Action Source URL
Htr6
Rattus norvegicus (Norway rat)
Full agonist
https://guidetopharmacology.org/GRAC/ObjectDisplayForward?objectId=11
HTR6
Homo sapiens (human)
Full agonist
https://guidetopharmacology.org/GRAC/ObjectDisplayForward?objectId=11
Rattus norvegicus (Norway rat)
Antagonist
https://guidetopharmacology.org/GRAC/ObjectDisplayForward?objectId=11
Htr6
Rattus norvegicus (Norway rat)
Antagonist
https://guidetopharmacology.org/GRAC/ObjectDisplayForward?objectId=11
Rattus norvegicus (Norway rat)
Antagonist
https://guidetopharmacology.org/GRAC/ObjectDisplayForward?objectId=11
Htr6
Rattus norvegicus (Norway rat)
Antagonist
https://guidetopharmacology.org/GRAC/ObjectDisplayForward?objectId=11
5-HT7
Drosophila melanogaster (fruit fly)
Bisphenol A results in decreased expression of 5-HT7 mRNA
https://ctdbase.org/detail.go?type=gene&acc=43669
Htr7
Mus musculus (house mouse)
Antagonist
https://guidetopharmacology.org/GRAC/ObjectDisplayForward?objectId=12
Htr7
Rattus norvegicus (Norway rat)
Partial agonist
https://guidetopharmacology.org/GRAC/ObjectDisplayForward?objectId=12
Htr7
Mus musculus (house mouse)
Full agonist
https://guidetopharmacology.org/GRAC/ObjectDisplayForward?objectId=12
Htr7
Rattus norvegicus (Norway rat)
Full agonist
https://guidetopharmacology.org/GRAC/ObjectDisplayForward?objectId=12
HTR7
Homo sapiens (human)
Full agonist
https://guidetopharmacology.org/GRAC/ObjectDisplayForward?objectId=12
HTR7
Homo sapiens (human)
Negative
https://guidetopharmacology.org/GRAC/ObjectDisplayForward?objectId=12
HTR7
Homo sapiens (human)
Full agonist
https://guidetopharmacology.org/GRAC/ObjectDisplayForward?objectId=12
Htr7
Rattus norvegicus (Norway rat)
Full agonist
https://guidetopharmacology.org/GRAC/ObjectDisplayForward?objectId=12
Htr7
Mus musculus (house mouse)
Full agonist
https://guidetopharmacology.org/GRAC/ObjectDisplayForward?objectId=12
Htr7
Rattus norvegicus (Norway rat)
Full agonist
https://guidetopharmacology.org/GRAC/ObjectDisplayForward?objectId=12
Htr7
Rattus norvegicus (Norway rat)
Full agonist
https://guidetopharmacology.org/GRAC/ObjectDisplayForward?objectId=12
Htr7
Mus musculus (house mouse)
Full agonist
https://guidetopharmacology.org/GRAC/ObjectDisplayForward?objectId=12
HTR7
Homo sapiens (human)
Full agonist
https://guidetopharmacology.org/GRAC/ObjectDisplayForward?objectId=12
HTR1A
Homo sapiens (human)
Agonist
https://www.drugbank.ca/bio_entities/BE0000291
HTR1A
Homo sapiens (human)
Bufotenin is a neurotoxin similar to the mushroom toxin psilocin. thus it likely acts as a partial agonist at the 5-HT2A serotonin receptor in the brain where it mimics the effects of serotonin (5-HT). it is likely also a 5-HT1A and 5-HT2A/2C agonist. (L1081, L1673)
http://www.t3db.ca/biodb/bio_entities/BE0000291
HTR1A
Homo sapiens (human)
Psilocybin is rapidly dephosphorylated in the body to psilocin which then acts as a partial agonist at the 5-HT2A serotonin receptor in the brain where it mimics the effects of serotonin (5-HT). psilocin is an 5-HT1A and 5-HT2A/2C agonist. (L1143)
http://www.t3db.ca/biodb/bio_entities/BE0000291
HTR1A
Homo sapiens (human)
http://www.t3db.ca/biodb/bio_entities/BE0000291
HTR1A
Homo sapiens (human)
Agonist
https://www.drugbank.ca/bio_entities/BE0000291
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