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SCFBio, IIT Delhi Hauz Khas, New Delhi
MOLECULAR TARGET

5-hydroxytryptamine receptor 1A

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26

Interactions

Homo sapiens (human)

Organism

HTR1A

Gene Name

Compound Associations

S.No BIMP ID Organism Action References
1 BIMP064165 Homo sapiens (human) Agonist
2 BIMP009815 Homo sapiens (human) Bufotenin is a neurotoxin similar to the mushroom toxin psilocin. thus it likely acts as a partial agonist at the 5-HT2A serotonin receptor in the brain where it mimics the effects of serotonin (5-HT). it is likely also a 5-HT1A and 5-HT2A/2C agonist. (L1081, L1673)
No ref
3 BIMP012019 Homo sapiens (human) Psilocybin is rapidly dephosphorylated in the body to psilocin which then acts as a partial agonist at the 5-HT2A serotonin receptor in the brain where it mimics the effects of serotonin (5-HT). psilocin is an 5-HT1A and 5-HT2A/2C agonist. (L1143)
No ref
4 BIMP066605 Homo sapiens (human) -
5 BIMP090555 Homo sapiens (human) -
6 BIMP081628 Homo sapiens (human) -
7 BIMP081628 Homo sapiens (human) -
8 BIMP081628 Homo sapiens (human) -
DOI
9 BIMP081628 Homo sapiens (human) -
10 BIMP078487 Homo sapiens (human) -
11 BIMP079116 Homo sapiens (human) Antagonist
12 BIMP080586 Homo sapiens (human) Other/unknown
13 BIMP079116 Homo sapiens (human) -
14 BIMP101253 Homo sapiens (human) -
15 BIMP101253 Homo sapiens (human) Agonist
16 BIMP104499 Homo sapiens (human) Agonist
17 BIMP105331 Homo sapiens (human) -
18 BIMP093437 Homo sapiens (human) Agonist
19 BIMP098141 Homo sapiens (human) -
20 BIMP091293 Homo sapiens (human) Partial agonist
21 BIMP091293 Homo sapiens (human) Aripiprazole exhibits high affinity for dopamine D2 and D3, serotonin 5-HT1A and 5- HT2A receptors, moderate affinity for dopamine D4, serotonin 5-HT2C and 5-HT7, alpha1-adrenergic and histamine H1 receptors and moderate affinity for the serotonin reuptake pump. aripiprazole has no appreciable affinity for cholinergic muscarinic receptors. aripiprazole functions as a partial agonist at the dopamine D2 and the serotonin 5-HT1A receptors, and as an antagonist at serotonin 5-HT2A receptor.
22 BIMP094590 Homo sapiens (human) Binder
23 BIMP094590 Homo sapiens (human) -
24 BIMP072654 Homo sapiens (human) -
25 BIMP071583 Homo sapiens (human) -
26 BIMP076721 Homo sapiens (human) -