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Interactions between compounds and specific gene/protein targets.
| BIMP_ID | Target Name | Gene | Organism | Action | Source URL |
|---|---|---|---|---|---|
|
ABCC2
|
Rattus norvegicus (Norway rat)
|
Boldine results in increased expression of ABCC2 mRNA
|
https://ctdbase.org/detail.go?type=gene&acc=1244
|
||
|
ABCC2
|
Mus musculus (house mouse)
|
[acetaminophen co-treated with propylene glycol] results in increased expression of ABCC2 mRNA
|
https://ctdbase.org/detail.go?type=gene&acc=1244
|
||
|
ABCC2
|
Rattus norvegicus (Norway rat)
|
Chrysophanic acid results in increased expression of ABCC2 mrna|chrysophanic acid results in increased expression of ABCC2 protein
|
https://ctdbase.org/detail.go?type=gene&acc=1244
|
||
|
ABCC2
|
Gallus gallus (chicken)
|
T-2 toxin results in decreased expression of ABCC2 mRNA
|
https://ctdbase.org/detail.go?type=gene&acc=1244
|
||
|
ABCC2
|
Danio rerio (zebrafish)
|
Cyclosporine affects the expression of ABCC2 mRNA
|
https://ctdbase.org/detail.go?type=gene&acc=1244
|
||
|
ABCC2
|
Homo sapiens (human)
|
Cyclosporine inhibits the reaction [ABCC2 protein results in increased transport of 5(6)-carboxy-2',7'-dichlorofluorescein]|cyclosporine affects the expression of ABCC2 mRNA
|
https://ctdbase.org/detail.go?type=gene&acc=1244
|
||
|
ABCC2
|
Homo sapiens (human)
|
Cyclosporine results in decreased activity of ABCC2 protein
|
https://ctdbase.org/detail.go?type=gene&acc=1244
|
||
|
ABCC2
|
Homo sapiens (human)
|
Cyclosporine results in decreased activity of ABCC2 protein|[cyclosporine results in decreased activity of ABCC2 protein] which affects the transport of 2-amino-1-methyl-6-phenylimidazo(4,5-b)pyridine
|
https://ctdbase.org/detail.go?type=gene&acc=1244
|
||
|
ABCC2
|
Homo sapiens (human)
|
[cyclosporine results in decreased activity of ABCC2 protein] which results in increased abundance of lithocholic acid
|
https://ctdbase.org/detail.go?type=gene&acc=1244
|
||
|
ABCC2
|
Homo sapiens (human)
|
Cyclosporine results in decreased expression of ABCC2 mRNA
|
https://ctdbase.org/detail.go?type=gene&acc=1244
|
||
|
ABCC2
|
Homo sapiens (human)
|
Cyclosporine results in increased expression of ABCC2 mRNA
|
https://ctdbase.org/detail.go?type=gene&acc=1244
|
||
|
ABCC2
|
Rattus norvegicus (Norway rat)
|
Cyclosporine inhibits the reaction [ABCC2 protein affects the transport of mycophenolic acid glucuronide]
|
https://ctdbase.org/detail.go?type=gene&acc=1244
|
||
|
ABCC2
|
Rattus norvegicus (Norway rat)
|
Cyclosporine inhibits the reaction [ABCC2 protein results in increased secretion of fluo-3]
|
https://ctdbase.org/detail.go?type=gene&acc=1244
|
||
|
ABCC2
|
Rattus norvegicus (Norway rat)
|
Cyclosporine results in decreased activity of ABCC2 protein
|
https://ctdbase.org/detail.go?type=gene&acc=1244
|
||
|
ABCC2
|
Rattus norvegicus (Norway rat)
|
Cyclosporine results in decreased expression of ABCC2 mRNA
|
https://ctdbase.org/detail.go?type=gene&acc=1244
|
||
|
ABCC2
|
Rattus norvegicus (Norway rat)
|
Cyclosporine results in increased expression of ABCC2 mRNA
|
https://ctdbase.org/detail.go?type=gene&acc=1244
|
||
|
ABCC2
|
Homo sapiens (human)
|
3',4',7-trihydroxyisoflavone results in decreased expression of ABCC2 mrna|cat protein inhibits the reaction [3',4',7-trihydroxyisoflavone results in decreased expression of ABCC2 mrna]|3',4',7-trihydroxyisoflavone inhibits the reaction [epirubicin results in increased expression of ABCC2 mrna]|ascorbic acid inhibits the reaction [3',4',7-trihydroxyisoflavone results in decreased expression of ABCC2 mrna]|acetylcysteine inhibits the reaction [3',4',7-trihydroxyisoflavone results in decreased expression of ABCC2 mrna]
|
https://ctdbase.org/detail.go?type=gene&acc=1244
|
||
|
ABCC2
|
Homo sapiens (human)
|
Myricetin inhibits the reaction [ABCC2 protein affects the export of vincristine]|abcc2 protein affects the export of and results in decreased susceptibility to vincristine|abcc2 protein affects the export of vincristine|myricetin inhibits the reaction [ABCC2 protein results in decreased susceptibility to vincristine]|myricetin inhibits the reaction [ABCC2 protein affects the export of and results in decreased susceptibility to vincristine]
|
https://ctdbase.org/detail.go?type=gene&acc=1244
|
||
|
ABCC2
|
Homo sapiens (human)
|
ABCC2 protein results in decreased susceptibility to vincristine
|
https://ctdbase.org/detail.go?type=gene&acc=1244
|
||
|
ABCC2
|
Homo sapiens (human)
|
[vincristine results in decreased susceptibility to vincristine] which results in increased expression of ABCC2 mRNA
|
https://ctdbase.org/detail.go?type=gene&acc=1244
|
||
|
ABCC2
|
Homo sapiens (human)
|
|
https://www.dgidb.org/genes/hgnc:53
|
||
|
ABCC2
|
Homo sapiens (human)
|
Sodium selenide inhibits the reaction [arsenite results in increased expression of ABCC2 protein]|abcc2 protein affects the transport of arsenite|sodium selenite inhibits the reaction [arsenite results in increased expression of ABCC2 protein]|abcc2 protein affects the reaction [sodium selenide results in increased transport of arsenite]
|
https://ctdbase.org/detail.go?type=gene&acc=1244
|
||
|
ABCC2
|
Homo sapiens (human)
|
Arsenite results in increased expression of ABCC2 mRNA
|
https://ctdbase.org/detail.go?type=gene&acc=1244
|
||
|
ABCC2
|
Homo sapiens (human)
|
Arsenite results in increased expression of ABCC2 protein
|
https://ctdbase.org/detail.go?type=gene&acc=1244
|
||
|
ABCC2
|
Homo sapiens (human)
|
[sodium arsenite results in increased abundance of arsenite] which results in increased expression of ABCC2 mRNA
|
https://ctdbase.org/detail.go?type=gene&acc=1244
|
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