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Interactions between compounds and specific gene/protein targets.
| BIMP_ID | Target Name | Gene | Organism | Action | Source URL |
|---|---|---|---|---|---|
|
ABCB4
|
Mus musculus (house mouse)
|
[caffeine co-treated with coclaurine co-treated with aegeline co-treated with higenamine co-treated with yohimbine co-treated with hydrolyzable tannins] results in increased expression of ABCB4 mRNA
|
https://ctdbase.org/detail.go?type=gene&acc=5244
|
||
|
ABCB4
|
Mus musculus (house mouse)
|
2,4-dichlorophenoxyacetic acid results in increased expression of ABCB4 mRNA
|
https://ctdbase.org/detail.go?type=gene&acc=5244
|
||
|
ABCB4
|
Mus musculus (house mouse)
|
[lard co-treated with cholesterol, dietary co-treated with dietary sucrose co-treated with fructose co-treated with glucose co-treated with 2,4-dichlorophenoxyacetic acid] results in increased expression of ABCB4 mRNA
|
https://ctdbase.org/detail.go?type=gene&acc=5244
|
||
|
ABCB4
|
Rattus norvegicus (Norway rat)
|
Schizandrin B inhibits the reaction [carbon tetrachloride results in decreased expression of ABCB4 mrna]
|
https://ctdbase.org/detail.go?type=gene&acc=5244
|
||
|
ABCB4
|
Mus musculus (house mouse)
|
Alisol B 23-acetate promotes the reaction [1-naphthylisothiocyanate results in increased expression of ABCB4 mrna]|alisol B 23-acetate promotes the reaction [1-naphthylisothiocyanate results in increased expression of ABCB4 protein]|pregna-4,17-diene-3,16-dione inhibits the reaction [alisol B 23-acetate promotes the reaction [1-naphthylisothiocyanate results in increased expression of ABCB4 mrna]]
|
https://ctdbase.org/detail.go?type=gene&acc=5244
|
||
|
ABCB4
|
Homo sapiens (human)
|
N-nitrosopyrrolidine results in decreased expression of ABCB4 mRNA
|
https://ctdbase.org/detail.go?type=gene&acc=5244
|
||
|
ABCB4
|
Homo sapiens (human)
|
[docetaxel results in decreased susceptibility to docetaxel] which results in increased expression of ABCB4 mRNA
|
https://ctdbase.org/detail.go?type=gene&acc=5244
|
||
|
ABCB4
|
Mus musculus (house mouse)
|
[caffeine co-treated with coclaurine co-treated with aegeline co-treated with higenamine co-treated with yohimbine co-treated with hydrolyzable tannins] results in increased expression of ABCB4 mRNA
|
https://ctdbase.org/detail.go?type=gene&acc=5244
|
||
|
ABCB4
|
Mus musculus (house mouse)
|
ABCB4 affects the secretion of cholic acid
|
https://ctdbase.org/detail.go?type=gene&acc=5244
|
||
|
ABCB4
|
Mus musculus (house mouse)
|
Cholic acid results in increased expression of ABCB4 mRNA
|
https://ctdbase.org/detail.go?type=gene&acc=5244
|
||
|
ABCB4
|
Mus musculus (house mouse)
|
Epiallopregnanolone sulfate inhibits the reaction [cholic acid results in increased expression of ABCB4 mrna]
|
https://ctdbase.org/detail.go?type=gene&acc=5244
|
||
|
ABCB4
|
Homo sapiens (human)
|
[glycochenodeoxycholic acid co-treated with deoxycholic acid co-treated with chenodeoxycholic acid co-treated with glycodeoxycholic acid co-treated with glycocholic acid] results in increased expression of ABCB4 mrna|[glycochenodeoxycholic acid co-treated with deoxycholic acid co-treated with chenodeoxycholic acid co-treated with glycodeoxycholic acid co-treated with glycocholic acid co-treated with acetaminophen] results in decreased expression of ABCB4 mrna|[glycochenodeoxycholic acid co-treated with deoxycholic acid co-treated with chenodeoxycholic acid co-treated with glycodeoxycholic acid co-treated with glycocholic acid co-treated with cyclosporine] results in decreased expression of ABCB4 mrna|[glycochenodeoxycholic acid co-treated with deoxycholic acid co-treated with chenodeoxycholic acid co-treated with glycodeoxycholic acid co-treated with glycocholic acid co-treated with atazanavir sulfate] results in decreased expression of ABCB4 mrna|[glycochenodeoxycholic acid co-treated with deoxycholic acid co-treated with chenodeoxycholic acid co-treated with glycodeoxycholic acid co-treated with glycocholic acid co-treated with tartrazine] results in decreased expression of ABCB4 mrna|[glycochenodeoxycholic acid co-treated with deoxycholic acid co-treated with chenodeoxycholic acid co-treated with glycodeoxycholic acid co-treated with glycocholic acid co-treated with nefazodone] results in increased expression of ABCB4 mRNA
|
https://ctdbase.org/detail.go?type=gene&acc=5244
|
||
|
ABCB4
|
Mus musculus (house mouse)
|
Deoxycholic acid affects the expression of ABCB4 mrna|slco1a1 protein affects the susceptibility to [deoxycholic acid affects the expression of ABCB4 mrna]
|
https://ctdbase.org/detail.go?type=gene&acc=5244
|
||
|
ABCB4
|
Mus musculus (house mouse)
|
Deoxycholic acid results in increased expression of ABCB4 mRNA
|
https://ctdbase.org/detail.go?type=gene&acc=5244
|
||
|
ABCB4
|
Mus musculus (house mouse)
|
Bisphenol A results in decreased expression of ABCB4 mRNA
|
https://ctdbase.org/detail.go?type=gene&acc=5244
|
||
|
ABCB4
|
Mus musculus (house mouse)
|
Bisphenol A results in increased expression of ABCB4 mRNA
|
https://ctdbase.org/detail.go?type=gene&acc=5244
|
||
|
ABCB4
|
Oryzias latipes (Japanese medaka)
|
Bisphenol A results in decreased expression of ABCB4 mRNA
|
https://ctdbase.org/detail.go?type=gene&acc=5244
|
||
|
ABCB4
|
Rattus norvegicus (Norway rat)
|
Bisphenol A results in decreased expression of ABCB4 mRNA
|
https://ctdbase.org/detail.go?type=gene&acc=5244
|
||
|
ABCB4
|
Rattus norvegicus (Norway rat)
|
Bisphenol A results in increased expression of ABCB4 mRNA
|
https://ctdbase.org/detail.go?type=gene&acc=5244
|
||
|
ABCB4
|
Homo sapiens (human)
|
Cycloheximide inhibits the reaction [tetradecanoylphorbol acetate results in decreased expression of ABCB4 mrna]
|
https://ctdbase.org/detail.go?type=gene&acc=5244
|
||
|
ABCB4
|
Mus musculus (house mouse)
|
Cannabidiol results in decreased expression of ABCB4 mRNA
|
https://ctdbase.org/detail.go?type=gene&acc=5244
|
||
|
ABCB4
|
Mus musculus (house mouse)
|
Pregna-4,17-diene-3,16-dione inhibits the reaction [alisol B 23-acetate promotes the reaction [1-naphthylisothiocyanate results in increased expression of ABCB4 mrna]]
|
https://ctdbase.org/detail.go?type=gene&acc=5244
|
||
|
ABCB4
|
Mus musculus (house mouse)
|
Dichloroacetic acid results in increased expression of ABCB4 mRNA
|
https://ctdbase.org/detail.go?type=gene&acc=5244
|
||
|
ABCB4
|
Rattus norvegicus (Norway rat)
|
Furan results in increased expression of ABCB4 mRNA
|
https://ctdbase.org/detail.go?type=gene&acc=5244
|
||
|
ABCB4
|
Mus musculus (house mouse)
|
Lithocholic acid results in increased expression of ABCB4 mRNA
|
https://ctdbase.org/detail.go?type=gene&acc=5244
|
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