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Interactions between compounds and specific gene/protein targets.
| BIMP_ID | Target Name | Gene | Organism | Action | Source URL |
|---|---|---|---|---|---|
|
ABCB4
|
Homo sapiens (human)
|
ABCB4 protein results in decreased susceptibility to doxorubicin
|
https://ctdbase.org/detail.go?type=gene&acc=5244
|
||
|
ABCB4
|
Homo sapiens (human)
|
Colforsin inhibits the reaction [doxorubicin results in increased expression of ABCB4 mrna]
|
https://ctdbase.org/detail.go?type=gene&acc=5244
|
||
|
ABCB4
|
Homo sapiens (human)
|
Doxorubicin results in increased expression of ABCB4 mRNA
|
https://ctdbase.org/detail.go?type=gene&acc=5244
|
||
|
ABCB4
|
Mus musculus (house mouse)
|
Ursodeoxycholic acid results in increased expression of ABCB4 mRNA
|
https://ctdbase.org/detail.go?type=gene&acc=5244
|
||
|
ABCB4
|
Homo sapiens (human)
|
[NOG protein co-treated with valproic acid co-treated with dorsomorphin co-treated with 4-(5-benzo(1,3)dioxol-5-yl-4-pyridin-2-yl-1H-imidazol-2-yl)benzamide] results in increased expression of ABCB4 mRNA
|
https://ctdbase.org/detail.go?type=gene&acc=5244
|
||
|
ABCB4
|
Homo sapiens (human)
|
Valproic acid affects the expression of ABCB4 mRNA
|
https://ctdbase.org/detail.go?type=gene&acc=5244
|
||
|
ABCB4
|
Homo sapiens (human)
|
Valproic acid results in decreased methylation of ABCB4 gene
|
https://ctdbase.org/detail.go?type=gene&acc=5244
|
||
|
ABCB4
|
Homo sapiens (human)
|
Valproic acid results in increased expression of ABCB4 mRNA
|
https://ctdbase.org/detail.go?type=gene&acc=5244
|
||
|
ABCB4
|
Homo sapiens (human)
|
Valproic acid results in increased expression of ABCB4 protein
|
https://ctdbase.org/detail.go?type=gene&acc=5244
|
||
|
ABCB4
|
Rattus norvegicus (Norway rat)
|
Valproic acid results in increased expression of ABCB4 mRNA
|
https://ctdbase.org/detail.go?type=gene&acc=5244
|
||
|
ABCB4
|
Homo sapiens (human)
|
Diclofenac results in decreased activity of ABCB4 protein
|
https://ctdbase.org/detail.go?type=gene&acc=5244
|
||
|
ABCB4
|
Homo sapiens (human)
|
Diclofenac results in decreased expression of ABCB4 mRNA
|
https://ctdbase.org/detail.go?type=gene&acc=5244
|
||
|
ABCB4
|
Mus musculus (house mouse)
|
[clofibrate co-treated with acetaminophen] affects the expression of ABCB4 mrna|ppara affects the reaction [[clofibrate co-treated with acetaminophen] affects the expression of ABCB4 mrna]
|
https://ctdbase.org/detail.go?type=gene&acc=5244
|
||
|
ABCB4
|
Mus musculus (house mouse)
|
Clofibrate results in increased expression of ABCB4 mRNA
|
https://ctdbase.org/detail.go?type=gene&acc=5244
|
||
|
ABCB4
|
Mus musculus (house mouse)
|
Ciprofibrate results in increased expression of ABCB4 mrna|ciprofibrate results in increased expression of ABCB4 protein
|
https://ctdbase.org/detail.go?type=gene&acc=5244
|
||
|
ABCB4
|
Mus musculus (house mouse)
|
Fumonisin B1 results in increased expression of ABCB4 mRNA
|
https://ctdbase.org/detail.go?type=gene&acc=5244
|
||
|
ABCB4
|
Mus musculus (house mouse)
|
[lard co-treated with cholesterol, dietary co-treated with dietary sucrose co-treated with fructose co-treated with glucose co-treated with 2,4-dichlorophenoxyacetic acid] results in increased expression of ABCB4 mRNA
|
https://ctdbase.org/detail.go?type=gene&acc=5244
|
||
|
ABCB4
|
Boreogadus saida
|
[benzo(a)pyrene co-treated with ethinyl estradiol] results in increased expression of ABCB4 mrna|benzo(a)pyrene results in increased expression of ABCB4 mRNA
|
https://ctdbase.org/detail.go?type=gene&acc=5244
|
||
|
ABCB4
|
Homo sapiens (human)
|
Benzo(a)pyrene affects the methylation of ABCB4 intron
|
https://ctdbase.org/detail.go?type=gene&acc=5244
|
||
|
ABCB4
|
Homo sapiens (human)
|
Benzo(a)pyrene results in decreased expression of ABCB4 mRNA
|
https://ctdbase.org/detail.go?type=gene&acc=5244
|
||
|
ABCB4
|
Homo sapiens (human)
|
Benzo(a)pyrene results in increased expression of ABCB4 mRNA
|
https://ctdbase.org/detail.go?type=gene&acc=5244
|
||
|
ABCB4
|
Homo sapiens (human)
|
Benzo(a)pyrene results in increased methylation of ABCB4 promoter|benzo(a)pyrene results in increased methylation of ABCB4 5' UTR
|
https://ctdbase.org/detail.go?type=gene&acc=5244
|
||
|
ABCB4
|
Mus musculus (house mouse)
|
[caffeine co-treated with coclaurine co-treated with aegeline co-treated with higenamine co-treated with yohimbine co-treated with hydrolyzable tannins] results in increased expression of ABCB4 mRNA
|
https://ctdbase.org/detail.go?type=gene&acc=5244
|
||
|
ABCB4
|
Homo sapiens (human)
|
Verapamil results in decreased activity of ABCB4 protein
|
https://ctdbase.org/detail.go?type=gene&acc=5244
|
||
|
ABCB4
|
Homo sapiens (human)
|
Verapamil results in decreased expression of ABCB4 mRNA
|
https://ctdbase.org/detail.go?type=gene&acc=5244
|
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