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Interactions between compounds and specific gene/protein targets.
| BIMP_ID | Target Name | Gene | Organism | Action | Source URL |
|---|---|---|---|---|---|
|
ABCB11
|
Homo sapiens (human)
|
Methyleugenol results in decreased expression of ABCB11 mRNA
|
https://ctdbase.org/detail.go?type=gene&acc=8647
|
||
|
ABCB11
|
Rattus norvegicus (Norway rat)
|
2,3,5,4'-tetrahydroxystilbene-2-O-beta-D-glucopyranoside affects the reaction [[emodin affects the activity of ABCB11 protein] which affects the export of taurocholic acid]|[2,3,5,4'-tetrahydroxystilbene-2-O-beta-D-glucopyranoside co-treated with emodin] results in increased expression of ABCB11 protein
|
https://ctdbase.org/detail.go?type=gene&acc=8647
|
||
|
ABCB11
|
Rattus norvegicus (Norway rat)
|
[cyproconazole co-treated with epoxiconazole co-treated with prochloraz] results in increased expression of ABCB11 mRNA
|
https://ctdbase.org/detail.go?type=gene&acc=8647
|
||
|
ABCB11
|
Homo sapiens (human)
|
Epigallocatechin gallate inhibits the reaction [chenodeoxycholic acid results in increased expression of ABCB11 mrna]|epigallocatechin gallate inhibits the reaction [GW 4064 results in increased expression of ABCB11 mrna]|epigallocatechin gallate results in increased expression of ABCB11 mRNA
|
https://ctdbase.org/detail.go?type=gene&acc=8647
|
||
|
ABCB11
|
Rattus norvegicus (Norway rat)
|
Epigallocatechin gallate results in decreased expression of ABCB11 mRNA
|
https://ctdbase.org/detail.go?type=gene&acc=8647
|
||
|
ABCB11
|
Mus musculus (house mouse)
|
Cannabidiol results in decreased expression of ABCB11 mRNA
|
https://ctdbase.org/detail.go?type=gene&acc=8647
|
||
|
ABCB11
|
Rattus norvegicus (Norway rat)
|
Ficusin results in decreased expression of ABCB11 mrna|ficusin results in decreased expression of ABCB11 protein
|
https://ctdbase.org/detail.go?type=gene&acc=8647
|
||
|
ABCB11
|
Rattus norvegicus (Norway rat)
|
Chloroform results in decreased expression of ABCB11 mRNA
|
https://ctdbase.org/detail.go?type=gene&acc=8647
|
||
|
ABCB11
|
Rattus norvegicus (Norway rat)
|
Colchicine affects the localization of ABCB11 protein
|
https://ctdbase.org/detail.go?type=gene&acc=8647
|
||
|
ABCB11
|
Mus musculus (house mouse)
|
Triptonide results in increased expression of ABCB11 mRNA
|
https://ctdbase.org/detail.go?type=gene&acc=8647
|
||
|
ABCB11
|
Homo sapiens (human)
|
[pregna-4,17-diene-3,16-dione co-treated with GW 4064] results in increased expression of ABCB11 mrna|pregna-4,17-diene-3,16-dione results in increased expression of ABCB11 mrna|[pregna-4,17-diene-3,16-dione co-treated with chenodeoxycholic acid] results in increased expression of ABCB11 mRNA
|
https://ctdbase.org/detail.go?type=gene&acc=8647
|
||
|
ABCB11
|
Homo sapiens (human)
|
Pregna-4,17-diene-3,16-dione inhibits the reaction [alisol B 23-acetate results in increased expression of ABCB11 protein]
|
https://ctdbase.org/detail.go?type=gene&acc=8647
|
||
|
ABCB11
|
Homo sapiens (human)
|
Pregna-4,17-diene-3,16-dione inhibits the reaction [bile acids and salts results in increased expression of ABCB11 mrna]|pregna-4,17-diene-3,16-dione inhibits the reaction [NR1H4 protein results in increased expression of ABCB11 mrna]
|
https://ctdbase.org/detail.go?type=gene&acc=8647
|
||
|
ABCB11
|
Homo sapiens (human)
|
Pregna-4,17-diene-3,16-dione inhibits the reaction [GW 4064 results in increased expression of ABCB11 mrna]
|
https://ctdbase.org/detail.go?type=gene&acc=8647
|
||
|
ABCB11
|
Mus musculus (house mouse)
|
Pregna-4,17-diene-3,16-dione inhibits the reaction [yangonin promotes the reaction [1-naphthylisothiocyanate results in increased expression of ABCB11 mrna]]|pregna-4,17-diene-3,16-dione inhibits the reaction [1-naphthylisothiocyanate results in increased expression of ABCB11 mrna]
|
https://ctdbase.org/detail.go?type=gene&acc=8647
|
||
|
ABCB11
|
Mus musculus (house mouse)
|
Pregna-4,17-diene-3,16-dione promotes the reaction [ethinyl estradiol results in decreased expression of ABCB11 mrna]|pregna-4,17-diene-3,16-dione inhibits the reaction [alisol B 23-acetate inhibits the reaction [ethinyl estradiol results in decreased expression of ABCB11 mrna]]
|
https://ctdbase.org/detail.go?type=gene&acc=8647
|
||
|
ABCB11
|
Mus musculus (house mouse)
|
Pregna-4,17-diene-3,16-dione inhibits the reaction [alisol B 23-acetate promotes the reaction [1-naphthylisothiocyanate results in increased expression of ABCB11 mrna]]
|
https://ctdbase.org/detail.go?type=gene&acc=8647
|
||
|
ABCB11
|
Mus musculus (house mouse)
|
Pregna-4,17-diene-3,16-dione inhibits the reaction [alisol B 23-acetate results in increased expression of ABCB11 mrna]
|
https://ctdbase.org/detail.go?type=gene&acc=8647
|
||
|
ABCB11
|
Homo sapiens (human)
|
Pregna-4,17-diene-3,16-dione results in increased expression of ABCB11 protein
|
https://ctdbase.org/detail.go?type=gene&acc=8647
|
||
|
ABCB11
|
Homo sapiens (human)
|
Efavirenz inhibits the reaction [ABCB11 protein results in increased transport of taurocholic acid]|efavirenz results in decreased activity of ABCB11 protein
|
https://ctdbase.org/detail.go?type=gene&acc=8647
|
||
|
ABCB11
|
Homo sapiens (human)
|
Tert-butylhydroperoxide results in decreased expression of ABCB11 mRNA
|
https://ctdbase.org/detail.go?type=gene&acc=8647
|
||
|
ABCB11
|
Rattus norvegicus (Norway rat)
|
1-(5-isoquinolinesulfonyl)-2-methylpiperazine inhibits the reaction [tert-butylhydroperoxide affects the localization of ABCB11 protein]|tert-butylhydroperoxide affects the localization of ABCB11 protein|bucladesine inhibits the reaction [tert-butylhydroperoxide affects the localization of ABCB11 protein]
|
https://ctdbase.org/detail.go?type=gene&acc=8647
|
||
|
ABCB11
|
Rattus norvegicus (Norway rat)
|
Bilirubin analog inhibits the reaction [tert-butylhydroperoxide affects the localization of and results in decreased activity of ABCB11 protein]|tert-butylhydroperoxide affects the localization of and results in decreased activity of ABCB11 protein
|
https://ctdbase.org/detail.go?type=gene&acc=8647
|
||
|
ABCB11
|
Homo sapiens (human)
|
[bisphenol A co-treated with fulvestrant] results in increased methylation of ABCB11 gene
|
https://ctdbase.org/detail.go?type=gene&acc=8647
|
||
|
ABCB11
|
Mus musculus (house mouse)
|
NR1H4 gene mutant form inhibits the reaction [[bisphenol A co-treated with stigmasterol] results in increased expression of ABCB11 mrna]|[bisphenol A co-treated with stigmasterol] results in increased expression of ABCB11 mRNA
|
https://ctdbase.org/detail.go?type=gene&acc=8647
|
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